Somatosensory Feedback for Neuroprosthetics covers all relevant aspects to facilitate learning, research and development in the field. The book starts with chapters reviewing the basic anatomy, physiology and psychophysics of the somatosensory system, sensorimotor control and instrumentation. Some sections are dedicated to invasive (peripheral and central, mainly cortical) and noninvasive (vibrotactile, electrotactile, etc.) approaches. Final chapters cover future technologies such as novel sensors and electrodes, safety, clinical testing, commercialization, and practical use, helping make up future prospects for this field with an emphasis on development and end-use. With contributions from renowned experts, users will find recent findings and technical details surrounding findings.
Although somatosensory system works in tandem with the motor system in biology, the majority of the prosthetics research and commercial efforts had focused on accommodating movement deficits. With the development of neuroprostheses in the last 15 years, it has become evident that somatosensory input (mainly as touch and proprioception) is essential for motor control, manipulating objects, and embodiment, in addition to its primary role for sensory perception.
- Provides a review of the somatosensory system and the latest advances in the use of somatosensory feedback for neuroprosthetics
- Analyzes many approaches to somatosensory feedback
- Provides the most detailed work on the somatosensory system, its development, and applications in real-life work
Part I: Background and fundamentals 1. Introduction to somatosensory neuroprostheses 2. Sense of touch and haptic perception 3. Proprioception for motor control 4. Sensorimotor integration in neuroprostheses 5. Electrodes and instrumentation for neurostimulation
Part II: Non-invasive methods for somatosensory feedback and modulation 6. Application with myoelectric prostheses 7. Vibrotactile psychophysics for sensory feedback in prostheses 8. Transcranial electrical stimulation for neuromodulation of somatosensory processing
Part III: Peripheral nerve implants for somatosensory feedback 9. Overview of sensory feedback in hand prostheses 10. Application with osseointegrated prostheses 11. Application with bi-directional hand prostheses 12. Another application with bi-directional hand prostheses
Part IV: Cortical implants for somatosensory feedback 13. Overview of sensory feedback to somatosensory cortex 14. Application with cortical surface electrodes in humans 15. Application with intracortical electrodes in humans 16. More extensive studies on cortical stimulation in monkeys 17. Intracortical microstimulation for tactile feedback in awake behaving rats
Part V: Future technologies 18. Novel electrodes for long-term tissue interfaces 19. Challenges in electronics and signal processing 20. Biomimetic approaches to somatosensory feedback 21. Targeted sensory reinnervation studies 22. Somatosensation in soft and anthropomorphic prosthetics 23. Prospect of data science and AI for patient-specific neuroprostheses
Part VI: Practical use of somatosensory neuroprostheses and conclusion 24. Safety and regulatory issues for clinical testing 25. Ethics, user acceptance, and commercial neuroprostheses 26. Concluding remarks
Prof. Güçlü has an engineering background (BS in 1997: control and computer engineering, Istanbul Technical University; MS in 1999: bioengineering, Syracuse University), completed PhD (2003, Syracuse University) and post-doctoral work (University of Rochester) in neuroscience mostly with specialization on the somatosensory system. He has over 20 years of experience in theoretical and experimental research involving the sense of touch in animals, humans, and for engineering applications such as neuroprosthetics and tactile sensors/displays. He has 47 articles published in refereed journals and over 100 publications in conferences. He has worked in grant projects funded by NIH, TÜBITAK, European Union and university agencies; is currently part of an EU consortium for the use of graphene electrodes in neuroprosthetics and has established Tactile Research Laboratory and the animal facility (Vivarium) at Bogaziçi University. He has taught courses on sensory systems, computational neuroscience, biophysics, and biomedical instrumentation, gave numerous lectures and provided media coverage on somatosensory feedback in neuroprosthetics.