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Endocarditis - Pipeline Insight, 2021

  • ID: 5237637
  • Drug Pipelines
  • February 2021
  • Region: Global
  • 60 pages
  • DelveInsight
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FEATURED COMPANIES

  • Basilea
  • ContraFect
  • MORE
This “Endocarditis - Pipeline Insight, 2021,” report provides comprehensive insights about 4+ companies and 4+ pipeline drugs in Endocarditis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Endocarditis Understanding

Endocarditis: Overview

Endocarditis, also known as infective endocarditis, is the inflammation and infection of the inner lining of the heart and heart valves which is known as the endocardium. The condition takes place with the entry of infectious organisms, such as fungi or bacteria into the bloodstream, after which they settle in the heart.

"Endocarditis - Pipeline Insight, 2021" report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Endocarditis pipeline landscape is provided which includes the disease overview and Endocarditis treatment guidelines. The assessment part of the report embraces, in depth Endocarditis commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Endocarditis collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Endocarditis R&D. The therapies under development are focused on novel approaches to treat/improve Endocarditis.
Endocarditis Emerging Drugs Chapters

This segment of the Endocarditis report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Endocarditis Emerging Drugs
  • Exebacase: ContraFect
Exebacase, also known as CF-301, is being developed by ContraFect for the first-in-class new treatment for patients with Staph aureus bacteriam including endocarditis. The Phase 2 trial of this drug showed positive results and the company plans to intiate Phase 3 trials soon. It has a rapid, specific and novel mechanism of action which targets the peptidoglycan wall of the Staph aureus bacteria. Further, many studies have also shown that Exebcase is highly effective against biofilms as well.

Endocarditis: Therapeutic Assessment

This segment of the report provides insights about the different Endocarditis drugs segregated based on following parameters that define the scope of the report, such as:

Major Players in Endocarditis

There are approx. 4+ key companies which are developing the therapies for Endocarditis. The companies which have their Endocarditis drug candidates in the mid to advanced stage, i.e. phase III and Phase II include, ContraFect and others.

The report covers around 10+ products under different phases of clinical development like
  • Mid-stage products (Phase II and Phase I/II)
  • Early-stage products (Phase I/II and Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Endocarditis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Subcutaneous
  • Intravenous
  • Oral
  • Intramuscular
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Small molecules
  • Natural metabolites
  • Monoclonal antibodies
  • Product Type
The drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Endocarditis: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Endocarditis therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Endocarditis drugs.

Endocarditis Report Insights
  • Endocarditis Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Endocarditis Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions Answered

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Endocarditis drugs?
  • How many Endocarditis drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Endocarditis?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Endocarditis therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Endocarditis and their status?
  • What are the key designations that have been granted to the emerging drugs?
Key Players
  • ContraFect
  • Basilea
Key Products
  • Exebacase
  • Ceftobiprole medocaril

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Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • Basilea
  • ContraFect
  • MORE
Introduction

Executive Summary

Endocarditis: Overview
  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management
Pipeline Therapeutics
  • Comparative Analysis
Therapeutic Assessment
  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type
Endocarditis - Analytical Perspective

In-depth Commercial Assessment
  • Endocarditis companies' collaborations, Licensing, Acquisition - Deal Value Trends
Endocarditis Collaboration Deals
  • Company-Company Collaborations (Licensing / Partnering) Analysis
  • Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  • Comparative Analysis
Exebacase: ContraFect
  • Product Description
  • Research and Development
  • Product Development Activities
Mid Stage Products (Phase II)
  • Comparative Analysis
  • Product Description
  • Research and Development
  • Product Development Activities
Pre-clinical and Discovery Stage Products
  • Comparative Analysis
  • Product Description
  • Research and Development
  • Product Development Activities
Inactive Products
  • Comparative Analysis
Endocarditis Key Companies

Endocarditis Key Products

Endocarditis - Unmet Needs

Endocarditis - Market Drivers and Barriers

Endocarditis - Future Perspectives and Conclusion

Endocarditis Analyst Views

Endocarditis Key Companies

Appendix

List of Tables
Table 1 Total Products for Endocarditis
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products

List of Figures
Figure 1 Total Products for Endocarditis
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
Note: Product cover images may vary from those shown
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  • ContraFect
  • Basilea
Note: Product cover images may vary from those shown
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