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Protein A Resin Market by Product (Agarose-based, Glass/Silica-based, Organic polymer-based), Type (Recombinant Protein A, Natural Protein A), Application (Antibody Purification, Immunoprecipitation), End User & Region - Global Forecast to 2028

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    Report

  • 145 Pages
  • April 2023
  • Region: Global
  • Markets and Markets
  • ID: 5238721

The global protein A resin market is projected to reach USD 2.1 billion by 2028 from USD 1.2 billion in 2022, growing at a CAGR of 9.8% during the forecast period. The rise in advantages offered by protein A resin to be used in therapeutics is one of the major factors anticipated to boost the market growth in the forecasting years.

The agarose-based protein A resin segment to hold the largest share of the market in 2022

On the basis of product, the protein A resin market is segmented into agarose-based protein A, glass/silica-based protein A, and organic polymer-based protein A. The agarose-based protein A segment commanded the largest share of the market in 2022, as agarose is the most widely used matrix resin for the attachment of ligands that bind proteins.

The recombinant protein A resin segment to hold the largest share of the market in 2022

On the basis of type, the protein A resin market is segmented into recombinant and natural protein A resin. The recombinant protein A segment accounted for a larger market share in 2022 and is estimated to register a higher CAGR during the forecast period. The high growth of this segment can be attributed to the increasing technological advancements for the discovery of drugs and antibody purifications.

The antibody purification segment is projected to register the highest CAGR during the forecast period

Based on application, the protein A resin market is segmented into antibody purification and immunoprecipitation. The antibody purification application segment dominated the market in 2022 and is expected to register a higher CAGR during the forecast period. The high growth of this segment can primarily be attributed to the increasing use in downstream processing of the antibodies and increasing demand for mAbs for therapeutic as well as research purposes.

The pharmaceutical & biopharmaceutical companies segment is projected to register the highest CAGR during the forecast period

The end-user market is segmented into pharmaceutical and biopharmaceutical companies, academic research institutes, and other end users. Pharmaceutical and biopharmaceutical companies accounted for the largest share of the global protein A resin market in 2022. This end-user segment is also estimated to grow at the highest CAGR during the forecast period. This can be attributed to the factors such as the increasing use of monoclonal antibodies in the therapeutic areas of different diseases like oncology, tuberculosis, and autoimmune diseases.

The market in the North America region is expected to hold significant market share for protein A resin in 2022

The protein A resin market covers five key geographies - North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. The market in the North American region is expected to hold a significant market share for protein A resin in 2022. The growth of the protein A resin market in this region can be attributed to the increasing investments in pharmaceutical R&D and government funding for R&D activities.

A breakdown of the primary participants referred to for this report is provided below:

  • By Company Type: Tier 1-48%, Tier 2-36%, and Tier 3- 16%
  • By Designation: C-level-10%, Director-level-14%, and Others-76%
  • By Region: North America-40%, Europe-32%, Asia Pacific-20%, Latin America-5%, and the Middle East & Africa-3%

The prominent players in the protein A resin market are Danaher Corporation (US), Merck KGaA (Germany), Repligen Corporation (US), Bio-Rad Laboratories, Inc. (US), Thermo Fisher Scientific Inc. (US), and Tosoh Corporation (Japan) among others.

Research Coverage

This report studies the protein A resin market based on product, type, application, end user and region. It also covers the factors affecting market growth, analyzes the various opportunities and challenges in the market, and provides details of the competitive landscape for market leaders. Furthermore, the report analyzes micro markets with respect to their individual growth trends and forecasts the revenue of the market segments with respect to five main regions (and the respective countries in these regions).

Reasons to Buy the Report 

The report will help the market leaders/new entrants in this market with information on the closest approximations of the revenue numbers for the overall C4ISR market and the subsegments. This report will help stakeholders understand the competitive landscape and gain more insights to position their businesses better and to plan suitable go-to-market strategies. The report also helps stakeholders understand the pulse of the market and provides them with information on key market drivers, restraints, challenges, and opportunities.

This report provides insights on the following pointers:

  • Analysis of key drivers (Need for enhanced integrated situational awareness to support decision making, modernization of defense capabilities to address asymmetric warfare threats, Rising Military focus on wireless connectivity and technologies), restraints (High Development and Maintenance costs of C4 System, Vulnerability to cyberattacks. Regulatory obstacles related to technology transfer), opportunities (Increasing need for interoperability between military devices/technologies. Incraesing use of AI to assist in effective decision making, Cloud computing and data storage solutions for C4ISR), and challenges (Inability of existing electronic warfare systems to address diverse threats) influencing the growth of the C4ISR market 
  • Product Development/Innovation: Detailed insights on upcoming technologies, research & development activities, and new product & service launches in the C4ISR market 
  • Market Development: Comprehensive information about lucrative markets - the report analyses the C4ISR market across varied regions 
  • Market Diversification: Exhaustive information about new products & services, untapped geographies, recent developments, and investments in the C4ISR market 
  • Competitive Assessment: In-depth assessment of market shares, growth strategies and service offerings of leading players like Lockheed Martin Corporation (US), Raytheon Technologies Corporation (US), Thales (France), BAE Systems Inc. (UK), General Dynamics Corporation (US), and Northrop Grumman (US), among others in the C4ISR market 
  • Product Development/Innovation: Detailed insights on the upcoming trends, R&D activities, and product launches in the protein A resin market
  • Market Development: Comprehensive information on lucrative emerging regions
  • Market Diversification: Exhaustive information about new products, growing geographies, and recent developments in the protein A resin market
  • Competitive Assessment: In-depth assessment of market segments, growth strategies, revenue analysis, and products of the leading market players.    

Table of Contents

1 Introduction
1.1 Study Objectives
1.2 Market Definition
1.3 Inclusions and Exclusions
Table 1 Protein a Resin Market: Inclusions and Exclusions
1.4 Markets Covered
Figure 1 Market Segmentation
1.4.1 Geographic Segmentation
1.5 Years Considered
1.6 Currency Considered
1.7 Limitations
1.8 Stakeholders
1.9 Summary of Changes

2 Research Methodology
2.1 Research Data
2.2 Recession Impact
Figure 2 Research Design
2.2.1 Secondary Research
2.2.2 Primary Research
2.2.2.1 Primary Sources
2.2.2.2 Key Industry Insights
2.2.2.3 Breakdown of Primaries
Figure 3 Breakdown of Primary Interviews: Supply-Side and Demand-Side Participants
Figure 4 Breakdown of Primary Interviews: by Company Type, Designation, and Region
2.3 Research Assumption
Figure 5 Research Methodology: Hypothesis Building
2.3.1 Bottom-Up Approach
2.3.1.1 Approach 1: Company Revenue Estimation Approach
Figure 6 Market Size Estimation: Vendor Revenue Mapping Approach
Figure 7 Analysis of Vendor Revenue Mapping
2.3.1.2 Approach 2: Customer-based Market Estimation
Figure 8 Market Size Estimation: Bottom-Up Approach
2.3.1.3 CAGR Projection
Figure 9 CAGR Projection: Supply-Side Analysis
2.4 Data Validation Approach
Figure 10 Data Triangulation Methodology
2.5 Market Share Assessment
2.6 Study Assumptions
2.7 Risk Assessment
2.7.1 Market: Risk Assessment
2.8 Growth Rate Assumptions

3 Executive Summary
Figure 11 Protein a Resin Market, by Product, 2022 vs. 2028 (USD Million)
Figure 12 Market, by Type, 2022 vs. 2028 (USD Million)
Figure 13 Market, by Application, 2022 vs. 2028 (USD Million)
Figure 14 Market, by End-user, 2022 vs. 2028 (USD Million)
Figure 15 Geographic Snapshot: Market

4 Premium Insights
4.1 Protein a Resin Market Overview
Figure 16 Increasing Demand for Pre-Packed Disposable Columns to Drive Market Growth
4.2 North America: Market, by Product, 2022 vs. 2028 (USD Million)
Figure 17 Agarose-based Protein a Segment to Dominate North American Market During Forecast Period
4.3 Asia-Pacific: Market, by End-user, 2022 vs. 2028 (USD Million)
Figure 18 Pharmaceutical and Biopharmaceutical Companies Segment to Continue to Dominate Asia-Pacific Market During Forecast Period
4.4 Geographic Snapshot of Market
Figure 19 China to Witness Highest Growth During Forecast Period

5 Market Overview
5.1 Introduction
5.2 Market Dynamics
Figure 20 Protein a Resin Market: Drivers, Restraints, Opportunities, and Challenges
5.2.1 Drivers
5.2.1.1 Growing Demand for Disposable Pre-Packed Columns
Table 2 Advantages of Pre-Packed Columns
5.2.1.2 Increasing Demand for Therapeutic Antibodies
5.2.1.3 Increasing Pharmaceutical R&D Spending
5.2.1.4 Stringent Regulatory Control in Healthcare Industry
5.2.2 Restraints
5.2.2.1 High Cost of Resins
5.2.2.2 Dearth of Skilled Professionals
5.2.3 Opportunities
5.2.3.1 Increasing Number of Cmos and Cros
5.2.4 Challenges
5.2.4.1 Regulatory Restrictions
5.2.4.2 Issues Associated with Scaling Up Production of Protein a Resins
5.3 Regulations
5.3.1 North America
5.3.1.1 US
5.3.1.2 Canada
5.3.2 Europe
5.3.3 Asia-Pacific
5.3.4 Latin America
5.3.5 Middle East & Africa
5.4 Pricing Analysis: Market
5.5 Porter's Five Forces Analysis
Table 3 Market: Porter's Five Forces Analysis
5.5.1 Threat of Substitutes
5.5.2 Bargaining Power of Suppliers
5.5.3 Bargaining Power of Buyers
5.5.4 Threat of New Entrants
5.5.5 Intensity of Competitive Rivalry

6 Protein A Resin Market, by Product
6.1 Introduction
Table 4 Market, by Product, 2020-2028 (USD Million)
6.2 Agarose-based Protein A
6.2.1 Agarose-based Protein A Segment to Dominate Market
Table 5 Agarose-based Protein A Market, by Region, 2020-2028 (USD Million)
Table 6 North America: Agarose-based Protein A Market, by Country, 2020-2028 (USD Million)
Table 7 Europe: Agarose-based Protein A Market, by Country, 2020-2028 (USD Million)
Table 8 Asia-Pacific: Agarose-based Protein A Market, by Country, 2020-2028 (USD Million)
6.3 Glass/Silica-based Protein A
6.3.1 Low Ph Tolerance of Silica-based Resins to Limit Their Market Growth
Table 9 Glass/Silica-based Protein A Market, by Region, 2020-2028 (USD Million)
Table 10 North America: Glass/Silica-based Protein A Market, by Country, 2020-2028 (USD Million)
Table 11 Europe: Glass/Silica-based Protein A Market, by Country, 2020-2028 (USD Million)
Table 12 Asia-Pacific: Glass/Silica-based Protein A Market, by Country, 2020-2028 (USD Million)
6.4 Organic Polymer-based Protein A
6.4.1 Increasing Popularity of Organic Polymers to Drive Market Growth
Table 13 Organic Polymer-based Protein A Market, by Region, 2020-2028 (USD Million)
Table 14 North America: Organic Polymer-based Protein A Market, by Country, 2020-2028 (USD Million)
Table 15 Europe: Organic Polymer-based Protein A Market, by Country, 2020-2028 (USD Million)
Table 16 Asia-Pacific: Organic Polymer-based Protein A Market, by Country, 2020-2028 (USD Million)

7 Protein A Resin Market, by Type
7.1 Introduction
Table 17 Market, by Type, 2020-2028 (USD Million)
7.2 Recombinant Protein A
7.2.1 Cost-Efficiency of Recombinant Proteins to Drive Market Growth
Table 18 Recombinant Protein A Market, by Region, 2020-2028 (USD Million)
7.3 Natural Protein A
7.3.1 Advantages of Recombinant Protein A Have Restricted Market Potential of Natural Protein A
Table 19 Natural Protein A Market, by Region, 2020-2028 (USD Million)

8 Protein A Resin Market, by Application
8.1 Introduction
Table 20 Market, by Application, 2020-2028 (USD Million)
8.2 Antibody Purification
8.2.1 Antibody Purification Segment to Dominate Market During Forecast Period
Table 21 Market for Antibody Purification, by Region, 2020-2028 (USD Million)
8.3 Immunoprecipitation
8.3.1 Immunoprecipitation Segment to Grow at Lower CAGR During Forecast Period
Table 22 Market for Immunoprecipitation, by Region, 2020-2028 (USD Million)

9 Protein A Resin Market, by End-user
9.1 Introduction
Table 23 Market, by End-user, 2020-2028 (USD Million)
9.2 Pharmaceutical and Biopharmaceutical Companies
9.2.1 Protein A Resins Extensively Used to Produce Biological Drugs
Figure 21 Spending on Pharmaceutical Research and Development, 2020-2028 (USD Billion)
Table 24 Market for Pharmaceutical and Biopharmaceutical Companies, by Region, 2020-2028 (USD Million)
9.3 Academic Research Institutes
9.3.1 Increasing R&D in Drug Discovery to Drive Use of Protein A Resins
Table 25 Market for Academic Research Institutes, by Region, 2020-2028 (USD Million)
9.4 Other End-users
Table 26 Market for Other End-users, by Region, 2020-2028 (USD Million)

10 Protein A Resin Market, by Region
10.1 Introduction
Table 27 Market, by Region, 2020-2028 (USD Million)
10.2 North America
Figure 22 North America: Protein A Resin Market Snapshot
Table 28 North America: Market, by Country, 2020-2028 (USD Million)
Table 29 North America: Market, by Product, 2020-2028 (USD Million)
Table 30 North America: Market, by Type, 2020-2028 (USD Million)
Table 31 North America: Market, by Application, 2020-2028 (USD Million)
Table 32 North America: Market, by End-user, 2020-2028 (USD Million)
10.2.1 US
10.2.1.1 Increasing R&D Investments in Pharmaceutical Industry to Propel Market Growth
Table 33 US: Market, by Product, 2020-2028 (USD Million)
10.2.2 Canada
10.2.2.1 Government Initiatives Focused on Boosting Pharmaceutical Industry to Drive Market Growth
Table 34 Canada: Market, by Product, 2020-2028 (USD Million)
10.3 Europe
Table 35 Europe: Protein A Resin Market, by Country, 2020-2028 (USD Million)
Table 36 Europe: Market, by Product, 2020-2028 (USD Million)
Table 37 Europe: Market, by Type, 2020-2028 (USD Million)
Table 38 Europe: Market, by Application, 2020-2028 (USD Million)
Table 39 Europe: Market, by End-user, 2020-2028 (USD Million)
10.3.1 Germany
10.3.1.1 Flourishing Biotechnology Industry to Drive Market Growth
Table 40 Germany: Protein A Resin Market, by Product, 2020-2028 (USD Million)
10.3.2 UK
10.3.2.1 Favorable R&D Scenario to Support Market Growth
Table 41 UK: Market, by Product, 2020-2028 (USD Million)
10.3.3 France
10.3.3.1 Favorable Healthcare Scenario to Boost Market Growth
Table 42 France: Market, by Product, 2020-2028 (USD Million)
10.3.4 Italy
10.3.4.1 Well-Established Pharmaceutical Industry to Spur Demand for Protein A Resins
Table 43 Italy: Market, by Product, 2020-2028 (USD Million)
10.3.5 Spain
10.3.5.1 Presence of a Large Number of Biotech R&D Service Providers to Support Market Growth
Table 44 Spain: Market, by Product, 2020-2028 (USD Million)
10.3.6 Rest of Europe
Table 45 Rest of Europe: Market, by Product, 2020-2028 (USD Million)
10.4 Asia-Pacific
Figure 23 Asia-Pacific: Protein A Resin Market Snapshot
Table 46 Asia-Pacific: Market, by Country, 2020-2028 (USD Million)
Table 47 Asia-Pacific: Market, by Product, 2020-2028 (USD Million)
Table 48 Asia-Pacific: Market, by Type, 2020-2028 (USD Million)
Table 49 Asia-Pacific: Market, by Application, 2020-2028 (USD Million)
Table 50 Asia-Pacific: Market, by End-user, 2020-2028 (USD Million)
10.4.1 Japan
10.4.1.1 Increasing Demand for Generic Drugs and Monoclonal Antibody Biosimilars to Drive Resin Consumption
Table 51 Japan: Market, by Product, 2020-2028 (USD Million)
10.4.2 China
10.4.2.1 Increasing Pharmaceutical R&D Spending to Drive Market Growth
Table 52 China: Market, by Product, 2020-2028 (USD Million)
10.4.3 India
10.4.3.1 Growth of Pharma and Biotech Industries to Drive Demand for Protein A Resins
Table 53 India: Protein A Resin Market, by Product, 2020-2028 (USD Million)
10.4.4 Australia
10.4.4.1 Increasing Demand for Protein-based Therapeutics for Treatment of Infectious Diseases to Drive Growth
Table 54 Australia: Market, by Product, 2020-2028 (USD Million)
10.4.5 South Korea
10.4.5.1 Developments in Biopharmaceutical Sector to Drive Market Growth
Table 55 South Korea: Market, by Product, 2020-2028 (USD Million)
10.4.6 Rest of Asia-Pacific
Table 56 Rest of Asia-Pacific: Market, by Product, 2020-2028 (USD Million)
10.5 Rest of the World
Table 57 RoW: Protein A Resin Market, by Product, 2020-2028 (USD Million)
Table 58 RoW: Market, by Type, 2020-2028 (USD Million)
Table 59 RoW: Market, by Application, 2020-2028 (USD Million)
Table 60 RoW: Market, by End-user, 2020-2028 (USD Million)

11 Competitive Landscape
11.1 Overview
11.2 Market Share Analysis
Figure 24 Protein A Resin Market Share Analysis (2021)
11.3 Competitive Leadership Mapping
11.3.1 Stars
11.3.2 Emerging Leaders
11.3.3 Pervasive Players
11.3.4 Participants
Figure 25 Market: Competitive Leadership Mapping (2022)
11.4 Competitive Scenario
11.4.1 Product Launches
Table 61 Market: Product Launches, January 2020 to February 2023
11.4.2 Deals
Table 62 Market: Deals, January 2020 to February 2023
11.4.3 Other Developments
Table 63 Market: Other Developments, January 2020 to February 2023

12 Company Profiles
12.1 Key Players
(Business Overview, Products/Services/Solutions Offered, Analyst's View, Key Strengths and Right to Win, Strategic Choices Made, Weaknesses and Competitive Threats, Recent Developments)*
12.1.1 Danaher Corporation
Table 64 Danaher Corporation: Company Overview
Figure 26 Danaher Corporation: Company Snapshot (2021)
12.1.2 Thermo Fisher Scientific
Table 65 Thermo Fisher Scientific: Company Overview
Figure 27 Thermo Fisher Scientific: Company Snapshot (2022)
12.1.3 Merck KGaA
Table 66 Merck KGaA: Company Overview
Figure 28 Merck KGaA: Company Snapshot (2022)
12.1.4 Repligen Corporation
Table 67 Repligen Corporation: Company Overview
Figure 29 Repligen Corporation: Company Snapshot (2022)
12.1.5 Tosoh Bioscience LLC
Table 68 Tosoh Bioscience LLC: Company Overview
Figure 30 Tosoh Bioscience LLC: Company Snapshot (2021)
12.1.6 Agilent Technologies, Inc.
Table 69 Agilent Technologies, Inc.: Company Overview
Figure 31 Agilent Technologies Inc.: Company Snapshot (2022)
12.1.7 Purolite
Table 70 Purolite: Company Overview
12.1.8 Perkinelmer Inc.
Table 71 Perkinelmer Inc.: Company Overview
Figure 32 Perkinelmer Inc.: Company Snapshot (2022)
12.1.9 Novasep Holding Sas
Table 72 Novasep Holding Sas: Company Overview
12.1.10 Genscript
Table 73 Genscript: Company Overview
Figure 33 Genscript: Company Snapshot (2021)
12.1.11 Bio-Rad Laboratories, Inc.
Table 74 Bio-Rad Laboratories, Inc.: Company Overview
Figure 34 Bio-Rad Laboratories, Inc.: Company Snapshot (2022)
12.1.12 Kaneka Corporation
Table 75 Kaneka Corporation: Company Overview
Figure 35 Kaneka Corporation: Company Snapshot (2021)
12.1.13 Orochem Technologies Inc.
Table 76 Orochem Technologies Inc.: Company Overview
12.1.14 Abcam PLC
Table 77 Abcam PLC.: Company Overview
12.1.15 Agarose Bead Technologies
Table 78 Agarose Bead Technologies: Company Overview
*Business Overview, Products/Services/Solutions Offered, Analyst's View, Key Strengths and Right to Win, Strategic Choices Made, Weaknesses and Competitive Threats, Recent Developments Might Not be Captured in Case of Unlisted Companies.
12.2 Other Companies
12.2.1 Avantor, Inc.
12.2.2 Jsr Lifesciences, LLC
12.2.3 Bio-Works
12.2.4 Takara Bio Inc.
12.2.5 Generon
12.2.6 Geno Technology Inc.
12.2.7 Jnc Corporation
12.2.8 Promega Corporation
12.2.9 Suzhou Nanomicro Technology Co. Ltd.
12.2.10 Transgen Biotech Co. Ltd.

13 Appendix
13.1 Discussion Guide

Companies Mentioned

  • Abcam PLC
  • Agarose Bead Technologies
  • Agilent Technologies, Inc.
  • Avantor, Inc.
  • Bio-Rad Laboratories, Inc.
  • Bio-Works
  • Danaher Corporation
  • Generon
  • Geno Technology Inc.
  • Genscript
  • JNC Corporation
  • JSR Lifesciences, LLC
  • Kaneka Corporation
  • Merck KGaA
  • Novasep Holding Sas
  • Orochem Technologies Inc.
  • Perkinelmer Inc.
  • Promega Corporation
  • Purolite
  • Repligen Corporation
  • Suzhou Nanomicro Technology Co. Ltd.
  • Takara Bio Inc.
  • Thermo Fisher Scientific
  • Tosoh Bioscience LLC
  • Transgen Biotech Co. Ltd.

Methodology

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