FEATURED COMPANIES
- Affinivax
- Merck Sharp &Dohme Corp.
- Pfizer
- SK Chemicals
- Vaxcyte
This “Pneumococcal Disease - Pipeline Insight, 2021,” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in the Pneumococcal Disease pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
Pneumococcal disease is an infection caused by the bacteria Streptococcus pneumoniae or pneumococcus. Disease is most common at the extremes of age, i.e, in young children and among the elderly. There are two main types of pneumococcal disease: non invasive and invasive with noninvasive being the less serious. Non Invasive Pneumococcal disease: it occurs outside the major organs of the blood and the bacteria can cause- Bronchitis, Sinusitis. Invasive pneumococcal diseases: Invasive pneumococcal diseases (IPDs) are more serious than the noninvasive type and occur inside a major organ or in a person's blood and the bacteria can cause: Pneumonia, Meningitis and sepsis. S. pneumoniae bacteria are common in the throat and nose. Bacteria can spread through droplets in the air and do not spread through contaminated food or water.
"Pneumococcal Disease - Pipeline Insight, 2021" report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Pneumococcal Disease pipeline landscape is provided which includes the disease overview and Pneumococcal Disease treatment guidelines. The assessment part of the report embraces, in depth Pneumococcal Disease commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Pneumococcal Disease collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
This segment of the Pneumococcal Disease report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
20 Valent Pneumococcal conjugate vaccine (20vPnC): Pfizer
Pfizer's 20vPnC vaccine candidate includes capsular polysaccharide conjugates for the 13 serotypes already included in Prevnar 13® (Pneumococcal 13-valent Conjugate Vaccine[Diphtheria CRM197 Protein]). The vaccine also contains capsular polysaccharide conjugates for seven additional serotypes that cause invasive pneumococcal disease. U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation for 20vPnC for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae serotypes in the vaccine candidate in adults age 18 years or older. If approved, 20vPnC will cover more serotypes responsible for the majority of pneumococcal disease than any other pneumococcal conjugate vaccine currently licensed or currently in late-stage clinical development. Importantly, 20vPnC has shown to induce immune memory, which provides protection and efficacy against non-bacteremic pneumonia, particularly in older adults.
ASP3772: Affinivax
ASP3772 utilizes the Multiple Antigen Presenting System (MAPS) platform which is Affinivax's proprietary, next-generation vaccine technology. MAPS vaccine can present both the polysaccharide and the protein antigens to the host immune system to induce both a B- and T-cell immune response. ASP3772 is a vaccine candidate that offers the potential to provide broader protection against pneumococcal disease. It is currently in phase II stage of development by Affinivax partnership with Astellas Pharma Inc., includes 24 pneumococcal serotypes.
There are approx. 5+ key companies which are developing the therapies for Pneumococcal Disease. The companies which have their Pneumococcal Disease drug candidates in the most advanced stage, i.e. pre-registration include, Pfizer.
The drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Pneumococcal Disease therapeutic drugs key players involved in developing key drugs.
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Pneumococcal Disease drugs.
Geography Covered
- Global coverage
Pneumococcal Disease Understanding
Pneumococcal Disease: Overview
Pneumococcal disease is an infection caused by the bacteria Streptococcus pneumoniae or pneumococcus. Disease is most common at the extremes of age, i.e, in young children and among the elderly. There are two main types of pneumococcal disease: non invasive and invasive with noninvasive being the less serious. Non Invasive Pneumococcal disease: it occurs outside the major organs of the blood and the bacteria can cause- Bronchitis, Sinusitis. Invasive pneumococcal diseases: Invasive pneumococcal diseases (IPDs) are more serious than the noninvasive type and occur inside a major organ or in a person's blood and the bacteria can cause: Pneumonia, Meningitis and sepsis. S. pneumoniae bacteria are common in the throat and nose. Bacteria can spread through droplets in the air and do not spread through contaminated food or water.
"Pneumococcal Disease - Pipeline Insight, 2021" report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Pneumococcal Disease pipeline landscape is provided which includes the disease overview and Pneumococcal Disease treatment guidelines. The assessment part of the report embraces, in depth Pneumococcal Disease commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Pneumococcal Disease collaborations, licensing, mergers and acquisition, funding, designations and other product related details.
Report Highlights
- The companies and academics are working to assess challenges and seek opportunities that could influence Pneumococcal Disease R&D. The therapies under development are focused on novel approaches to treat/improve Pneumococcal Disease.
Pneumococcal Disease Emerging Drugs Chapters
This segment of the Pneumococcal Disease report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.
Pneumococcal Disease Emerging Drugs
20 Valent Pneumococcal conjugate vaccine (20vPnC): Pfizer
Pfizer's 20vPnC vaccine candidate includes capsular polysaccharide conjugates for the 13 serotypes already included in Prevnar 13® (Pneumococcal 13-valent Conjugate Vaccine[Diphtheria CRM197 Protein]). The vaccine also contains capsular polysaccharide conjugates for seven additional serotypes that cause invasive pneumococcal disease. U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation for 20vPnC for the prevention of invasive disease and pneumonia caused by Streptococcus pneumoniae serotypes in the vaccine candidate in adults age 18 years or older. If approved, 20vPnC will cover more serotypes responsible for the majority of pneumococcal disease than any other pneumococcal conjugate vaccine currently licensed or currently in late-stage clinical development. Importantly, 20vPnC has shown to induce immune memory, which provides protection and efficacy against non-bacteremic pneumonia, particularly in older adults.
ASP3772: Affinivax
ASP3772 utilizes the Multiple Antigen Presenting System (MAPS) platform which is Affinivax's proprietary, next-generation vaccine technology. MAPS vaccine can present both the polysaccharide and the protein antigens to the host immune system to induce both a B- and T-cell immune response. ASP3772 is a vaccine candidate that offers the potential to provide broader protection against pneumococcal disease. It is currently in phase II stage of development by Affinivax partnership with Astellas Pharma Inc., includes 24 pneumococcal serotypes.
Pneumococcal Disease: Therapeutic Assessment
This segment of the report provides insights about the different Pneumococcal Disease drugs segregated based on following parameters that define the scope of the report, such as:
Major Players in Pneumococcal Disease
There are approx. 5+ key companies which are developing the therapies for Pneumococcal Disease. The companies which have their Pneumococcal Disease drug candidates in the most advanced stage, i.e. pre-registration include, Pfizer.
Phases
The report covers around 5+ products under different phases of clinical development like
- Late stage products (Phase III)
- Mid-stage products (Phase II and Phase I/II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
- Route of Administration
The Pneumococcal Disease pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
- Intravenous
- Subcutaneous
- Topical.
- Molecule Type
Products have been categorized under various Molecule types such as
- Peptides
- Vaccines
- Gene therapy
- Product Type
The drugs have been categorized under various product types like Mono, Combination and Mono/Combination.
Pneumococcal Disease: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Pneumococcal Disease therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Pneumococcal Disease drugs.
Pneumococcal Disease Report Insights
- Pneumococcal Disease Pipeline Analysis
- Therapeutic Assessment
- Unmet Needs
- Impact of Drugs
Pneumococcal Disease Report Assessment
- Pipeline Product Profiles
- Therapeutic Assessment
- Pipeline Assessment
- Inactive drugs assessment
- Unmet Needs
Key Questions Answered
Current Treatment Scenario and Emerging Therapies:
- How many companies are developing Pneumococcal Disease drugs?
- How many Pneumococcal Disease drugs are developed by each company?
- How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Pneumococcal Disease?
- What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Pneumococcal Disease therapeutics?
- What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
- What are the clinical studies going on for Pneumococcal Disease and their status?
- What are the key designations that have been granted to the emerging drugs?
Key Players
- Pfizer
- Affinivax
- Merck Sharp &Dohme Corp.
- Vaxcyte
- SK Chemicals
Key Products
- 20vPnC
- V114
- ASP3772
- VAX-A1
- Pneumococcal vaccine conjugate
Note: Product cover images may vary from those shown
FEATURED COMPANIES
- Affinivax
- Merck Sharp &Dohme Corp.
- Pfizer
- SK Chemicals
- Vaxcyte
IntroductionExecutive SummaryPneumococcal Disease - Analytical PerspectivePneumococcal Disease Key CompaniesPneumococcal Disease Key ProductsPneumococcal Disease - Unmet NeedsPneumococcal Disease - Market Drivers and BarriersPneumococcal Disease - Future Perspectives and ConclusionPneumococcal Disease Analyst ViewsPneumococcal Disease Key CompaniesAppendix
Pneumococcal Disease: Overview
Pipeline Therapeutics
Therapeutic Assessment
In-depth Commercial Assessment
Pneumococcal Disease Collaboration Deals
Late Stage Products (Pre-registration)
Mid Stage Products (Phase II)
ASP3772: Affinivax
Early Stage Products (Phase I)
Drug Name: Company Name
Inactive Products
List of Tables
List of Figures
Note: Product cover images may vary from those shown
A selection of companies mentioned in this report includes:
- Pfizer
- Affinivax
- Merck Sharp &Dohme Corp.
- Vaxcyte
- SK Chemicals
Note: Product cover images may vary from those shown