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Discovery and Development of Anti-Breast Cancer Agents from Natural Products. Natural Product Drug Discovery

  • Book

  • June 2021
  • Elsevier Science and Technology
  • ID: 5308539

Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields.

Discovery and Development of Anti-Breast Cancer Agents from Natural Products will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for breast cancer, highlighting a number of key structures from natural products and exploring possible future developments in the area.

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Table of Contents

1. Discovery and Development of Anti-Breast Cancerous Agents From Natural Products: An Overview
2. Epothilones A and B: The 16-Membered Natural Macrolides as a Fascinating Template for Antibreast Cancer Drug Discovery
3. Anti-Breast Cancer Terpenoids of Natural Origins
4. Vinca Alkaloids as Chemotherapeutic Agents Against Breast Cancer
5. Cannabinoids and Breast Cancer
6. Carotenoids as Tools in Breast Cancer Therapy
7. Flavonoids as Inducers of Apoptosis and Autophagy in Breast Cancer
8. Phytoestrogens as Novel Therapeutic Molecules Against Breast Cancer
9. Chemopreventive and Therapeutic Potential of Natural Agents and Their Combinations for Breast Cancer
10. Nanoparticles for Delivering Natural Product Chemotherapeutics to Breast Cancer Cells
11. Molecular Mechanisms Underlying Breast Cancer and Role of Plant Products in Targeted Therapy

Authors

Goutam Brahmachari Goutam Brahmachari, PhD
Full Professor, Organic Chemistry, Department of Chemistry,
Visva-Bharati (a Central University), Santiniketan, West Bengal, India. Born on April 14, 1969 in Barala, a village in the district of Murshidabad (West Bengal, India), Goutam Brahmachari had his early education in his native place. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher Secondary Education (WBCHSE). Then he moved to Visva-Bharati (a Central University founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, he completed his master's in 1992 with a specialization in organic chemistry. After that, receiving his Ph.D. in 1997 in chemistry from the same university, he joined his alma mater the very next year and currently holds the position of a full professor of chemistry since 2011. The research interests of Prof. Brahmachari's group include natural products chemistry, synthetic organic chemistry, green chemistry, and the medicinal chemistry of natural and natural product-inspired synthetic molecules. With about 23 years of experience in teaching and research, he has produced 235 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and green chemistry. He has already authored/edited 26 books published by internationally reputed major publishing houses, namely, Elsevier Science (The Netherlands), Academic Press (Oxford), Wiley-VCH (Germany), Alpha Science International (Oxford), De Gruyter (Germany), World Scientific (Singapore), CRC Press (Taylor & Francis Group, USA), Royal Society of Chemistry (Cambridge), etc. Prof. Brahmachari serves as a life member for the Indian Association for the Cultivation of Science (IACS), Indian Science Congress Association (ISCA), Kolkata, and Chemical Research Society of India (CRSI), Bangalore. He has also been serving as an associate editor for Current Green Chemistry.

Prof. Brahmachari serves as the founder series editor of Elsevier Book Series' Natural Product Drug Discovery. He is an elected fellow of the Royal Society of Chemistry, and a recipient of CRSI (Chemical Research Society of India) Bronze Medal, 2021 (contributions to research in chemistry), INSA (Indian National Science Academy) Teachers Award, 2019, Dr. Kalam Best Teaching Faculty Award, 2017, and Academic Brilliance Award, 2015 (Excellence in Research). Prof. Brahmachari was featured in the World's Top 2% Scientists (organic chemistry category) in 2020 and 2021 and the AD Scientific Index 2022 World Ranking of Scientists, 2022.