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Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood. Micro and Nano Technologies

  • Book

  • September 2021
  • Elsevier Science and Technology
  • ID: 5308585

Nanotechnology for Hematology, Blood Transfusion, and Artificial Blood outlines the fundamental design concepts and emerging applications of nanotechnology in hematology, blood transfusion and artificial blood. This book is an important reference source for materials scientists, engineers and biomedical scientists who are looking to increase their understanding of how nanotechnology can lead to more efficient blood treatments. Sections focus on how nanotechnology could offer new routes to address challenging and pressing issues facing rare blood diseases and disorders and how nanomaterials can be used as artificial cell-like systems (compartmentalized biomimetic nanocontainers), which are especially useful in drug delivery.

For artificial blood, the nanotechnological approach can fabricate artificial red blood cells, platelet substitutes, and white blood cell substitutes with their inherent enzyme and other supportive systems. In addition, nanomaterials can promote blood vessel growth and reserve red blood cells at a positive temperature.

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Table of Contents

PART 1: FUNDAMENTALS 1. Blood-nano interface: an introduction 2. Blood- nanomaterials interactions 3. Immune system nanomaterials interactions 4. Uptake by reticuloendothelial system (RES) of the injected nanoparticles 5. Biomimetic nanomedicine: an introduction 6. Transport of nanoparticles in blood flow: Mathematical simulation 7. Effect of nanoparticle on the blood coagulation system (Nanoparticle interface with the blood coagulation system) 8. Toxicity/risk assessment of nanomaterials when used in hematology, blood transfusion and artificial blood

PART 2: HEMATOLOGY 9. Lab-on-a-chip (Lab-on-a-phone) for analysis of blood (diagnosis of blood diseases) 10. Nanotechnology for blood test to predict the blood diseases or blood disorders 11.�Nanopharmacology�in translational hematology and oncology (Nanotechnology applications in hematological malignancies) 12. Target-specific ligands loaded nanomagnets�for� blood�purification (removal of pathogens without fouling of filter membranes) 13. Nanomaterials- based circulating artificial bioreactor for replacement of blood components 14. Drug delivery systems based on blood cells

PART 3: BLOOD TRANSFUSION 15. Smart blood transfusion: An introduction 16. Nanofiltration 17. Nanotechnology for the preservation of red blood cells 18. Nanotechnology for destroying blood clots

PART 4: ARTIFICIAL BLOOD 19. Artificial red blood cells 20. Platelet substitutes 21. WBC substitutes 22. Future scope

Authors

Adil Denizli Professor, Hacettepe University, Department of Chemistry, Ankara, Turkey. Adil Denizli is Professor at Hacettepe University, Department of Chemistry, Ankara, Turkey. His main research fields are molecular imprinting technologies, purification of biomolecules by chromatographic methods, detection of molecules by sensors, production of polymers with different surface and bulk properties, shape and geometries, and application of these polymers in different applications. Mariappan Rajan Assistant Professor, Department of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, India. Mariappan Rajan is currently working as an Assistant Professor in the Department of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, India. He is an experienced researcher and is mainly interested in the development of biodegradable polymeric nanocarrier systems, nanogels, nanoparticles, nanocomposite scaffolds, bio-ceramic materials and mineral substituted scaffold for Tissue engineering, Drug Delivery and Wound Dressing applications. Mohammad Feroz Alam Assistant Professor, Department of Pathology, J.N Medical College, Aligarh Muslim University, Aligarh, India. Area of interest are Hematology, Histopathology, Cancer research and Nanomedicine. Mohammad Feroz Alam M.D (Pathology) is an Assistant Professor at J.N Medical College, AMU. He has an experience of nearly 16 years in Teaching and Research work.His areas of interest are Hematology, Histopathology, Cancer research and Nanomedicine Khaliqur Rahman Associate Professor, Hematology Laboratory, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India. Khaliqur Rahman is an Associate Professor in the Hematology Laboratory at Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India. His areas of research are molecular diagnostic of hematolymphoid neoplasm and advancement in flow cytometric immunophenotyping and minimal residual disease evaluation. Tuan Anh Nguyen Senior Principal Research Scientist, Institute for Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. Tuan Anh Nguyen is Principal Research Scientist at the Institute for Tropical Technology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. His research focuses on advanced nanomaterials and nanotechnology for corrosion and materials integrity in transportation systems. His research activities include smart coatings, conducting polymers, corrosion and protection of metals/concrete, antibacterial materials, and advanced nanomaterials.