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Black Seeds (Nigella sativa). Pharmacological and Therapeutic Applications

  • Book

  • September 2021
  • Elsevier Science and Technology
  • ID: 5308604

Black Seeds (Nigella sativa) is a comprehensive resource covering all aspects of this medicinal plant, well-known for its positive effects in many human ailments. It has been used to promote health and fight diseases, and has been found to have antioxidant, antihypertensive, anti-diabetic, anti-inflammatory, and analgesic effects. It has also been known to have antimicrobial, anticancer, neuro-protectant, cardio protectant, immunomodulator, hepatic protectant characteristics. Thymoquinone, the active compound of the plant, also exhibits these protective qualities against many disorders. This book summarizes the effect of this plant on all the organ systems of the body. Black Seeds (Nigella sativa) is a comprehensive resource for researchers working in pharmacology, food chemistry and pharmaceutical chemistry, both in industry and academia.

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Table of Contents

1. History and traditional uses of Black seeds (Nigella sativa)

2. Nigella sativa: From Chemistry to Medicine

3. Nigella sativa, a cure for every disease: Phytochemistry, Biological Activities and Clinical Trials

4. A Review of Nigella sativa and its Active Principles as Anticancer Agents

5. Dermatological effects of Nigella sativa: A cosmetic and therapeutic approach

6. Nigella sativa and its chemical constituents: A promising approach against neurodegenerative disorders

7. A Meta-analysis of Nigella sativa in Respiratory Disorders

8. Nigella sativa and its active principles: Potential food for healthy living

9. Therapeutic effects of Nigella sativa on hormonal dysfunctions

10. The cardio protective effect of thymoquinone from Nigella sativa

11. Black seeds of Nigella Sativa: a remedy for advanced cancer therapeutics with special reference to nanotechnology

12. Nigella sativa as a Therapeutic Candidate for Arthritis and Related Disorders

13. Therapeutic potential of Nigella sativa in the Prevention of Aggregation and Glycation of Proteins

14. Role of Nigella sativa as immunomodulator

15. Gastrointestinal abnormalities and Nigella sativa: A Narrative Review of Preclinical and Clinical Studies

16. Anti-viral effects of black seeds: Effect on COVID-19

17. Black Seed (Nigella Sativa): Pharmacological and Therapeutic Applications in endocrine dysfunction

18. Nigella sativa and Prevention of Nephrotoxicity: A Comprehensive update

19. Nigella sativa: A promise for industrial and agricultural economic growth

Authors

Andleeb Khan Assistant Professor, Jazan University, Saudi Arabia. Andleeb Khan (Ph.D.) is Assistant Professor at Jazan University, Saudi Arabia. She has completed her doctorate from Jamia Hamdard, New Delhi, India in Toxicology with specialization in natural and active constituents from plants for prevention of Alzheimer's Disease. She has teaching and research experience of more than ten years in neurodegenerative disorders and their prevention with medicinal plants, their active principles and nanoformulations. She has published her research in national and international journals and contributed many book chapters with international publishers including Springer Nature and Elsevier. Currently, Dr. Khan is engaged in studying the molecular mechanism of Azheimer's disease, Ischemic stroke, Parkinson's Disease and their prevention by various active principles from natural sources and nanoformulations. Muneeb U Rehman College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Muneeb U Rehman (Ph.D.) is a Faculty member at College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. He holds a doctorate in Toxicology (specialization in cancer biology and natural product research) from Jamia Hamdard, New Delhi, India. Dr. Rehman has more than 10 years of research and teaching experience in the field of toxicology, cancer biology, natural product pharmacology and pharmacogenomics. He is the recipient of several national and international fellowships and awards. He has published more than 100 research papers in peer-reviewed, international journals, and has 5 edited books and 30 book chapters. Dr. Rehman is on the editorial boards and is a reviewer of several high-impact, international scientific journals. He is also a life member of various international societies and organizations. Currently, Dr. Rehman is engaged in studying the molecular mechanisms of cancer prevention by natural products and the role of pharmacogenomics and toxicogenomics in evaluating the effectiveness and safety of drugs.