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Tamoxifen Tales

  • ID: 5308634
  • Book
  • September 2021
  • 320 Pages
  • Elsevier Science and Technology
Tamoxifen Tales: Suggestions for Scientific Survival presents a case study describing the academic journey of teams behind major advances in medical sciences, highlighting the lessons learned from this journey that are applicable to the scientific journey of the next generation of scientists. This book provides a manual on the successful mentoring of young scientists including stories describing how training experience shaped careers to become leaders in academia and the pharmaceutical industry. The book documents Professor V. Craig Jordan's 50-year career in medical sciences that led to the discovery and development of Selective Estrogen Receptor Modulators (SERMs), which became the standard of women's healthcare around the world. The SERM Raloxifene revolutionized disease treatment by simultaneously preventing breast cancer and osteoporosis. The SERM tamoxifen marked the first targeted therapy in cancer. It provides a unique account of Professor Jordan's life as a medical scientist, the only individual not in law enforcement trained as a narcotic officer by the Drug Enforcement Administration in America, and an intelligence officer in the Special Air Service (SAS). The book illustrates the versatility of a scientist in the real world with a commitment to serving societies. Tamoxifen Tales: Suggestions for Scientific Survival will be a useful and interesting book for established medical scientists, research mentors, and advanced students wanting to chart a successful and impactful research career.
  • Highlights the lessons learned from the journey behind discovery science, which are applicable to the scientific journey of the next generation of scientists
  • Provides a manual on the successful mentoring of young scientists to become leaders in academia and the pharmaceutical industry
  • Examines cancer treatment based on a personal determination to challenge at the frontiers of the science and to relate to personal life experience
  • Includes references for further research reading
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1. Leeds University: foundation of a career 2. The chance to be a PhD student at Leeds University 3. A new strategy: long-term adjuvant tamoxifen therapy first proposed at Leeds University 4. Two opportunities! 5. Academic advancement 6. Two new challenges in cancer centers 7. Four decades of discovery 8. Sliding door and serendipity 9. Closing the circle on tamoxifen tales 10. Reborn in Texas 11. Case studies: in their own words 12. Scientific survival suggestions 13. Appendices

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Jordan, V Craig
V. Craig Jordan is Professor of Breast Medical Oncology, Professor of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX. Previously, he was Scientific Director and Vice Chairman of Oncology at the Lombardi Comprehensive Cancer Center of Georgetown University. Jordan was the first to discover the breast cancer prevention properties of tamoxifen and the scientific principles for adjuvant therapy with antihormones. More recently his work has branched out into the prevention of multiple diseases in women with the discovery of the drug group, selective estrogen receptor modulator (SERMs). Currently, he plans to develop a new Hormone Replacement Therapy (HRT) for post-menopausal women that prevents breast cancer and does not increase the risk of breast cancer. In 2019 he was appointed Companion of the Most Distinguished Order of St. Michael and St. George by Queen Elizabeth II for services to women's health.
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