Diagnosis, Management and Modeling of Neurodevelopmental Disorders: The Neuroscience of Development is a comprehensive reference on the diagnosis and management of neurodevelopment and associated disorders. The book discusses the mechanisms underlying neurological development and provides readers with a detailed introduction to the neural connections and complexities in biological circuitries, as well as the interactions between genetics, epigenetics and other micro-environmental processes. In addition, the book also examines the pharmacological and non-pharmacological interventions of development-related conditions.
Table of Contents
I. Introductory Chapters: Setting the Scene for the Neuroscience of Development 1. The brain and its structures: An overview 2. Neural tube defects: Embryonic origin, clinical features and cell survival equilibrium impact 3. Chemical substances affecting neurodevelopment 4. High-risk babies and Neurodevelopmental outcome 5. Genomic Imprinting and neurodevelopment 6. Insights from model systems: Alcohol, neurodevelopment and zebrafish 7. Early life nutrition and brain development: Maternal iodine nutrition and neurodevelopment 8. Endocrine Aspects of Development. Thyroid hormone actions in neurological processes during brain development
II. Impairments and Diseases 9. Pediatric brain tumors 10. Neurofibromatosis Type 1: From cellular phenotypes to human brain function 11. The role and development of neural crest cells 12. Spina Bifida: A Biopsychosocial Perspective 13. Diabetic ketoacidosis and neurodevelopment 14. Four-dimensional features of fetal brain: Applications to diabetes 15. Prenatally exposed to nicotine and neurodevelopment 16. Maternal methamphetamine and impact on the brain 17. Alcohol, cannabis and brain development 18. The Environmental Pollutant Trichloroethylene Disrupts Key Neural Pathways During Brain Development 19. Developmental neurotoxicity of the herbicide atrazine 20. Neurodevelopmental delays and in utero hyperemesis gravidarum 21. Neurodevelopment and Infantile Epileptic Encephalopathy-9 (EIEE9) 22. Neurodevelopment in Turner syndrome 23. Very preterm children and the impact on neurodevelopmental outcomes 24. Linking congenital heart disease and brain functional connectivity in newborns 25. Brain Growth in Congenital Heart Disease from Prenatal Environment to Adulthood 26. Linking dopamine, amphetamine and neurodevelopment 27. Developmental coordination disorder
III. Biomarkers, Screening, Methods and Diagnosis 28. Neurodevelopment and the The Ages and Stages Questionnaire, third edition (ASQ-3) 29. Screening for Attention Deficit Hyperactivity Disorder in children 30. The Mini-Mental State Pediatric Examination screening tool: Italian perspectives 31. Predictors of neurodevelopment in preterm infants: From the neonatal intensive care unit into adulthood 32. The antenatal fetal neurodevelopmental test: Uses and applications
IV: Management and Treatments 33. Pain, evaluation and management in neurodevelopmental conditions 34. Use of levetiracetam: Features and applications to neonatal seizures 35. Quetiapine treatment in paediatric scenarios 36. Treatments with cannabinoids and brain development 37. Pediatric dystonia and deep brain stimulation 38. Use of repetitive transcranial magnetic stimulation in neurodevelopment:ï¿½A narrative review 39. Cognitive behavioral therapy in children with anxiety disorders 40. Cognitive behavioral therapy for anxiety in children with autism spectrum disorder 41. Nutritional treatment in fetal alcohol spectrum disorder 42. Nurturing the Developing Brain to Reduce Neurological Delay 43. Normalizing perinatal neurological development via intervention
V. Models and Modelling 44. Microplatforms as a Model for Neurological Conditions 45. Disease models in neurodevelopmental disorders 46. Endosulfan and impact on neurodevelopment: Modelling with zebrafish (Danio rerio) 47. Neurodevelopment of the zebrafish spinal serotonin system 48. Inbred mouse model of brain development and intestinal microbiota 49. The myelin mutant taiep rat as a model of developmental disorder 50. The MAM-E17 neurodevelopmental model of schizophrenia
VI. Resources 51. Research and recommended resources in the neuroscience of development
AuthorsColin R Martin Professor of Clinical Psychobiology and Applied Psychoneuroimmunology and Clinical Director: Institute for Health and Wellbeing
University of Suffolk, Ipswich, UK. : Dr. Martin is a Professor of Mental Health at Buckinghamshire New University. He is a Registered Nurse, Chartered Health Psychologist, and a Chartered Scientist. He has published or has in press well over 250 research papers and book chapters. He is a keen book author and editor having written and/or edited several books all of which reflect his diverse academic and clinical interests that examine in-depth, the interface between mental health and physical health. These outputs include the Handbook of Behavior; Food and Nutrition (2011), Perinatal Mental Health: A Clinical Guide (2012); Nanomedicine and the Nervous System (2012), and the major reference works Comprehensive Guide to Autism (2014), Diet and Nutrition in Dementia and Cognitive Decline (2015), Comprehensive Guide to Post-Traumatic Stress Disorder (2016) and Metabolism and Pathophysiology of Bariatric Surgery: Nutrition, Procedures, Outcomes, and Adverse Effects (2017). Victor R Preedy Professor in the Department of Clinical Biochemistry at King's College Hospital, London, UK
Emeritus Professor in Faculty of Life Sciences and Medicine at King's College London, UK Visiting Professor at the University of Hull, UK. Professor Preedy has been elected as a Fellow to the following Royal Societies: The Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health and Hygiene, the Royal Society for Public Health, the Royal Society of Chemistry, and the Royal Society of Medicine. He was founding Director of the Genomics Centre at King's College London and held the post from 2006 to 2020. He is a leading expert on the science of health and has a long-standing interest in disease processes, biomarkers, and tissue pathology. He has lectured nationally and internationally. Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes. Rajkumar Rajendram Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia. Dr. Rajkumar Rajendram is a clinician scientist with a focus is on internal medicine, intensive care, and infectious diseases. He is currently a Consultant in Internal Medicine at King Abdulaziz Medical City, National Guard Heath Affairs, Riyadh, Saudi Arabia. Dr Rajendram has extensive expertise in the management of infection and recognizes that emerging infectious diseases such as Monkeypox are a significant threat to health worldwide. He was an affiliated member of The Faculty of Life Sciences and Medicine, King's College London for over twenty years and has published over 350 textbook chapters, review articles, peer-reviewed papers, and abstracts.