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Obesity - Pipeline Insight, 2021

  • ID: 5351710
  • Clinical Trials
  • June 2021
  • Region: Global
  • 60 pages
  • DelveInsight

FEATURED COMPANIES

  • 10xBio
  • Carmot Therapeutics
  • EraCal Therapeutics
  • Kintai Therapeutics
  • Novo Nordisk
  • Saniona
This “Obesity - Pipeline Insight, 2021” report provides comprehensive insights about 50+ companies and 50+ pipeline drugs in Obesity pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
  • Global coverage
Obesity Understanding

Obesity: Overview

A person whose weight is higher than what is considered as a normal weight adjusted for height is described as being overweight or having obesity. Factors that may contribute to weight gain among adults and youth include genes, eating habits, physical inactivity, TV, computer, phone, and other screen time, sleep habits, medical conditions or medications, and where and how people live, including their access to healthy foods and safe places to be active. Overweight and obesity are risk factors for many health problems such as type 2 diabetes, high blood pressure, joint problems, and gallstones, among other conditions.

"Obesity - Pipeline Insight, 2021" report by the publisher outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Obesity pipeline landscape is provided which includes the disease overview and Obesity treatment guidelines. The assessment part of the report embraces, in depth Obesity commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Obesity collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Obesity R&D. The therapies under development are focused on novel approaches to treat/improve Obesity.
Obesity Emerging Drugs Chapters

This segment of the Obesity report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Obesity Emerging Drugs

Tirzepatide: Eli Lilly and Company

Tirzepatide is a once-weekly dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that integrates the actions of both incretins into a single novel molecule. GIP is a hormone that may complement the effects of GLP-1 receptor agonists. In preclinical models, GIP has been shown to decrease food intake and increase energy expenditure therefore resulting in weight reductions, and when combined with a GLP-1 receptor agonist, may result in greater effects on glucose and body weight. Tirzepatide is in phase 3 stage of development for the treatment of obesity.

Danuglipron: Pfizer

Danuglipron (formerly PF 06882961) is an orally administered, small molecule, glucagon-like peptide 1 receptor (GLP 1R) agonist, being developed by Pfizer. The drug is currently in phase 2 stage of development for the treatment of obesity.

Noiiglutide: Jiangsu Hansoh Pharmaceutical

Noiiglutide is a glucagon-like peptide-1 (GLP-1) analogue being developed by Jiangsu Hansoh Pharmaceutical for the treatment of obesity. Currently, it is in phase 2 stage of development.

MEDI 0382: MedImmune

MEDI0382 is an oxyntomodulin-like peptide with targeted GLP-1 and glucagon receptor activity. MEDI0382 was discovered and developed in MedImmune's labs and is a dual agonist using natural amino acids. Currently, it is in phase 2 stage of development for the treatment of obesity.

Obesity: Therapeutic Assessment

This segment of the report provides insights about the different Obesity drugs segregated based on following parameters that define the scope of the report, such as:

Major Players in Obesity

There are approx. 50+ key companies which are developing the therapies for Obesity. The companies which have their Obesity drug candidates in the most advanced stage, i.e. phase III include, Eli Lilly and Company.

Phases

This report covers around 50+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration
Obesity pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical.
  • Molecule Type
Products have been categorized under various Molecule types such as
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
The drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Obesity: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Obesity therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Obesity drugs.

Obesity Report Insights
  • Obesity Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Obesity Report Assessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs
Key Questions Answered

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Obesity drugs?
  • How many Obesity drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Obesity?
  • What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Obesity therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Obesity and their status?
  • What are the key designations that have been granted to the emerging drugs?
Key Players
  • Eli Lilly and Company
  • Pfizer
  • Jiangsu Hansoh Pharmaceutical
  • MedImmune
  • Can-Fite Biopharma
  • Novo Nordisk
  • 10xBio
  • Biolingus
  • Shionogi
  • Boehringer Ingelheim
  • Saniona
  • Diasome Pharmaceuticals
  • Empros Pharma
  • Amgen
  • ERX Pharmaceuticals
  • Innovent Biologics
  • Otsuka Pharmaceutical
  • Kyowa Kirin Co., Ltd.
  • Raziel Therapeutics
  • Hanmi Pharmaceutical
  • YSOPIA Biosciences
  • Allysta Pharmaceutical
  • pH Pharma
  • Gannex Pharma
  • Neuraly, Inc.
  • NGM Biopharmaceuticals, Inc
  • Glaceum
  • Carmot Therapeutics
  • LG Chem. Life sciences
  • CohBar
  • Scohia Pharma
  • Click Therapeutics
  • YUHAN
  • UGISense AG
  • Kanion Huawe Pharmaceutical
  • OPKO Health
  • EraCal Therapeutics
  • Kintai Therapeutics
  • NovmetaPharma
Key Products
  • Tirzepatide
  • Danuglipron
  • Noiiglutide
  • MEDI 0382
  • Namodenoson
  • NN 9838
  • Polidocanol
  • BL OPUS I
  • Semaglutide subcutaneous
  • S 237648
  • NNC 01651875
  • Peptide YY
  • BI 456906
  • LY 3305677
  • Tesofensine
  • HDV Biotin
  • BI 1356225
  • EMP16-02
  • AMG 171
  • ERX1000
  • IBI362
  • AMG 133
  • BI 456906
  • NO-13065
  • Bardoxolone methyl
  • RZL-012
  • Efinopegdutide
  • Xla1
  • ALY688-SR
  • PHP-303
  • ASC 41
  • DD01
  • NGM395
  • HSG4112
  • CT-388
  • LR19156
  • LR19020
  • CB4211
  • SCO-272
  • SCO-267
  • SCO-094
  • CT-181
  • YH34160
  • YHC2129
  • YHC2134
  • CT 868
  • Metoprolol/tesofensine
  • OPK-88003
  • KTX-0200
  • NovOB
Note: Product cover images may vary from those shown

FEATURED COMPANIES

  • 10xBio
  • Carmot Therapeutics
  • EraCal Therapeutics
  • Kintai Therapeutics
  • Novo Nordisk
  • Saniona
Introduction

Executive Summary

Obesity: Overview
  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management
Pipeline Therapeutics
  • Comparative Analysis
Therapeutic Assessment
  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type
Obesity - Analytical Perspective

In-depth Commercial Assessment
  • Obesity companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Obesity Collaboration Deals
  • Company-Company Collaborations (Licensing / Partnering) Analysis
  • Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  • Comparative Analysis
Tirzepatide: Eli Lilly and Company
  • Product Description
  • Research and Development
  • Product Development Activities
Mid Stage Products (Phase II)
  • Comparative Analysis
Danuglipron: Pfizer
  • Product Description
  • Research and Development
  • Product Development Activities
Early Stage Products (Phase I)
  • Comparative Analysis
ERX1000: ERX Pharmaceuticals
  • Product Description
  • Research and Development
  • Product Development Activities
Inactive Products
  • Comparative Analysis
Obesity Key Companies

Obesity Key Products

Obesity- Unmet Needs

Obesity- Market Drivers and Barriers

Obesity- Future Perspectives and Conclusion

Obesity Analyst Views

Obesity Key Companies

Appendix

List of Tables
Table 1 Total Products for Obesity
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products

List of Figures
Figure 1 Total Products for Obesity
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
Note: Product cover images may vary from those shown
  • 10xBio
  • Allysta Pharmaceutical
  • Amgen
  • Biolingus
  • Boehringer Ingelheim
  • Can-Fite Biopharma
  • Carmot Therapeutics
  • Click Therapeutics
  • CohBar
  • Diasome Pharmaceuticals
  • Eli Lilly and Company
  • Empros Pharma
  • EraCal Therapeutics
  • ERX Pharmaceuticals
  • Gannex Pharma
  • Glaceum
  • Hanmi Pharmaceutical
  • Innovent Biologics
  • Jiangsu Hansoh Pharmaceutical
  • Kanion Huawe Pharmaceutical
  • Kintai Therapeutics
  • Kyowa Kirin Co., Ltd.
  • LG Chem. Life sciences
  • MedImmune
  • Neuraly, Inc.
  • NGM Biopharmaceuticals, Inc
  • NovmetaPharma
  • Novo Nordisk
  • OPKO Health
  • Otsuka Pharmaceutical
  • Pfizer
  • pH Pharma
  • Raziel Therapeutics
  • Saniona
  • Scohia Pharma
  • Shionogi
  • UGISense AG
  • YSOPIA Biosciences
  • YUHAN
Note: Product cover images may vary from those shown
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