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Dipeptidyl peptidase 4 inhibitors - Pipeline Insight, 2022

  • ID: 5354322
  • Report
  • January 2022
  • Region: Global
  • 60 Pages
  • DelveInsight

FEATURED COMPANIES

  • BioXcel Therapeutics
  • Boehringer Ingelheim
  • Dong-A ST
  • Recardio
This “Dipeptidyl Peptidase 4 Inhibitors - Pipeline Insight, 2022” report provides comprehensive insights about 8+ companies and 8+ pipeline drugs in Dipeptidyl Peptidase 4 Inhibitors pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered

  • Global coverage

Dipeptidyl Peptidase 4 Inhibitors Understanding

Dipeptidyl Peptidase 4 Inhibitors: Overview


Dipeptidyl-peptidase-4 (DPP4, also known as CD26) is a membrane glycoprotein that is well known for its role in the catalytic degradation of incretins. DPP4 inhibitors (DPP4i), as a class of antidiabetic medications, have been accepted worldwide, owing to their ease of administration, modest effects on HbA1c, and lack of serious side effects. DPP4 inhibition in experimental models has uniformly demonstrated cardioprotective effects.

Dipeptidyl peptidase 4 (DPP-4) inhibitors are a class of medicine that lower high blood glucose levels and may be used in the treatment of type 2 diabetes. DPP-4 inhibitors slow the inactivation and degradation of GLP-1, a hormone involved in glucose removal from the gut. DPP-4 inhibitors improve blood glucose control and reduce both fasting and postprandial (after food) blood glucose levels, without causing weight gain. They do not usually cause hypoglycemia (low blood sugar levels) unless they are combined with other therapies that cause hypoglycemia.

Report Highlights
  • The companies and academics are working to assess challenges and seek opportunities that could influence Dipeptidyl Peptidase 4 Inhibitors R&D. The therapies under development are focused on novel approaches for Dipeptidyl Peptidase 4 Inhibitors.

Dipeptidyl Peptidase 4 Inhibitors Emerging Drugs Chapters


This segment of the Dipeptidyl Peptidase 4 Inhibitors report encloses its detailed analysis of various drugs in different stages of clinical development, including phase III, II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Dipeptidyl Peptidase 4 Inhibitors Emerging Drugs

HSK7653: Haisco Pharmaceutical Group

HSK7653 is a new oral drug for the treatment of type 2 diabetes with independent intellectual property rights developed by Haisco. It is intended to be used for the treatment of type 2 diabetes. HSK7653, as a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), can increase the plasma levels of endogenous glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) Concentration, promotes insulin secretion in a glucose concentration-dependent manner, and ultimately improves blood sugar control.

It is currently in Phase III stage of development and is being developed by Haisco Pharmaceutical Group.

DA-1229: Dong-A ST

DA-1229 is an orally available small molecule agonist of the thyroid hormone receptor that is being approved for Type 2 diabetes mellitus but it is currently in Phase II stage of development for the treatment of Calcific Aortic Valve Disease and is being developed by Dong-A ST.

Dipeptidyl Peptidase 4 Inhibitors: Therapeutic Assessment


This segment of the report provides insights about the different Dipeptidyl Peptidase 4 Inhibitors drugs segregated based on following parameters that define the scope of the report, such as:

Major Players working on Dipeptidyl Peptidase 4 Inhibitors


There are approx. 8+ key companies which are developing the Dipeptidyl Peptidase 4 Inhibitors. The companies which have their Dipeptidyl Peptidase 4 Inhibitors drug candidates in the most advanced stage, i.e. Phase III include, Haisco Pharmaceutical Group.

Phases


This report covers around 8+ products under different phases of clinical development like

  • Late-stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage products (Phase I/II and Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration

Dipeptidyl Peptidase 4 Inhibitors pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

  • Infusion
  • Intradermal
  • Intramuscular
  • Intranasal
  • Intravaginal
  • Oral
  • Parenteral
  • Subcutaneous
  • Topical
  • Molecule Type

Products have been categorized under various Molecule types such as

  • Vaccines
  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Product Type

The drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Dipeptidyl Peptidase 4 Inhibitors: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase III, II, I, preclinical and discovery stage. It also analyses Dipeptidyl Peptidase 4 Inhibitors therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Dipeptidyl Peptidase 4 Inhibitors drugs.

Dipeptidyl Peptidase 4 Inhibitors Report Insights

  • Dipeptidyl Peptidase 4 Inhibitors Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Dipeptidyl Peptidase 4 Inhibitors Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions


Current Scenario and Emerging Therapies:

  • How many companies are developing Dipeptidyl Peptidase 4 Inhibitors drugs?
  • How many Dipeptidyl Peptidase 4 Inhibitors drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for Dipeptidyl Peptidase 4 Inhibitors?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Dipeptidyl Peptidase 4 Inhibitors therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Dipeptidyl Peptidase 4 Inhibitors and their status?
  • What are the key designations that have been granted to the emerging drugs?

Key Players

  • Boehringer Ingelheim
  • Haisco Pharmaceutical Group
  • BioXcel Therapeutics
  • Recardio
  • Dong-A ST
  • CSPC ZhongQi Pharmaceutical Technology
  • Chia Tai Tianqing Pharmaceutical Group

Key Products

  • Linagliptin
  • HSK7653
  • BXCL 701
  • Dutogliptin
  • DA-1229
  • DBPR108
  • TQ-F3083


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Note: Product cover images may vary from those shown

FEATURED COMPANIES

  • BioXcel Therapeutics
  • Boehringer Ingelheim
  • Dong-A ST
  • Recardio
Introduction

Executive Summary

Dipeptidyl Peptidase 4 Inhibitors: Overview
  • Structure
  • Mechanism of Action

Pipeline Therapeutics
  • Comparative Analysis

Therapeutic Assessment
  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type

Dipeptidyl Peptidase 4 Inhibitors - Analytical Perspective

In-depth Commercial Assessment
  • Dipeptidyl Peptidase 4 Inhibitors companies’ collaborations, Licensing, Acquisition -Deal Value Trends

Dipeptidyl Peptidase 4 Inhibitors Collaboration Deals
  • Company-Company Collaborations (Licensing / Partnering) Analysis
  • Company-University Collaborations (Licensing / Partnering) Analysis

Late Stage Products (Phase III)
  • Comparative Analysis

HSK7653: Haisco Pharmaceutical Group
  • Product Description
  • Research and Development
  • Product Development Activities

Mid Stage Products (Phase II)
  • Comparative Analysis

Dutogliptin: Recardio
  • Product Description
  • Research and Development
  • Product Development Activities

Early Stage Products (Phase I)
  • Comparative Analysis

Drug Name: Company Name
  • Product Description
  • Research and Development
  • Product Development Activities

Preclinical and Discovery Stage Products
  • Comparative Analysis

Drug Name: Company Name
  • Product Description
  • Research and Development
  • Product Development Activities

Inactive Products
  • Comparative Analysis

Dipeptidyl Peptidase 4 Inhibitors Key Companies

Dipeptidyl Peptidase 4 Inhibitors Key Products

Dipeptidyl Peptidase 4 Inhibitors - Unmet Needs

Dipeptidyl Peptidase 4 Inhibitors - Market Drivers and Barriers

Dipeptidyl Peptidase 4 Inhibitors - Future Perspectives and Conclusion

Dipeptidyl Peptidase 4 Inhibitors Analyst Views

Dipeptidyl Peptidase 4 Inhibitors Key Companies

Appendix


List of Tables
Table 1 Total Products for Dipeptidyl Peptidase 4 Inhibitors
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products


List of Figures
Figure 1 Total Products for Dipeptidyl Peptidase 4 Inhibitors
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products
Note: Product cover images may vary from those shown

A selection of companies mentioned in this report includes:

  • Boehringer Ingelheim
  • Haisco Pharmaceutical Group
  • BioXcel Therapeutics
  • Recardio
  • Dong-A ST
  • CSPC ZhongQi Pharmaceutical Technology
  • Chia Tai Tianqing Pharmaceutical Group
Note: Product cover images may vary from those shown