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Diagnostic Pathology: Nonneoplastic Pediatrics. Edition No. 2

  • Book

  • January 2023
  • Elsevier Health Science
  • ID: 5390361
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of nonneoplastic pediatric pathology, it incorporates the most recent clinical, pathological, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, Diagnostic Pathology: Nonneoplastic Pediatrics, second edition, is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource.
  • Provides a clear framework for a better understanding of the clinical and histopathologic appearances of more than 270 nonneoplastic entities, covering every organ system with a focus on reactive, infectious, congenital, and genetic conditions�

  • Covers significant advances in this complex field, including recent molecular discoveries and updated disease entities, new information on multiple immunologic disorders, changes and expansions to several classification systems (such as WHO, Banff, and ISSVA), and updates in other scoring systems�

  • Contains new chapters on manifestations of pediatric COVID-19 infection, tumoral calcinosis, multiple skeletal dysplasia, skeletal muscle, collagenous gastritis and colitis, adenovirus appendicitis, intestinal pseudoobstruction, disorders of sexual development, and Kikuchi disease�

  • Includes approximately 3,000 high-quality clinical and histologic images, gross pathology images, radiologic images, and full-color illustrations to help practicing and in-training pathologists reach a confident diagnosis-as well as nearly 200 additional images online�

  • Employs consistently templated chapters and bulleted content for quick, expert reference at the point of care�

  • Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud�

Table of Contents

Skin

Spongiotic and Psoriasiform Dermatoses

1 Pityriasis Rosea

2 Contact Dermatitis

3 Atopic Dermatitis

4 Perniosis

5 Seborrheic Dermatitis

Inflammatory/Interface Dermatoses

6 Erythema Multiforme and Related Disorders

7 Pityriasis Lichenoides

Vesicobullous Dermatoses

8 Acropustulosis of Infancy

9 Dermatitis Herpetiformis

10 Epidermolysis Bullosa-Inherited

11 Erythema Toxicum Neonatorum

12 Hailey-Hailey Disease

13 Chronic Bullous Disease of Childhood

14 Transient Neonatal Pustular Melanosis

Vascular and Related Diseases

15 Urticaria and Variants

16 Leukocytoclastic Vasculitis

Paniculitides

17 Erythema Nodosum

18 Subcutaneous Fat Necrosis of the Newborn

19 Sclerema Neonatorum

Connective Tissue

20 Lupus Erythematosus

21 Morphea/Scleroderma

22 Dermatomyositis

Metabolic/Deposition Diseases

23 Calcinosis Cutis

Noninfectious Granulomatous Diseases

24 Chalazion

25 Granuloma Annulare

Pilosebaceous Disease

26 Acne Vulgaris

Alopecias

27 Trichotillomania

Disorders of Epidermal Maturation and Keratinization

28 Ichthyosis

29 Darier Disease

30 Porokeratosis

31 Incontinentia Pigmenti

Disorder of Collagen

32 Aplasia Cutis Congenita

Bacterial Infections

33 Impetigo

34 Staphylococcal Scalded Skin Syndrome

35 Ecthyma

36 Necrotizing Fasciitis

37 Cat Scratch Disease

38 Atypical Mycobacterial Infections

Viral Infections

39 Molluscum Contagiosum

40 Herpesvirus

Fungal Infections

41 Candidiasis

Arthropods/Parasites

42 Bite Reactions

43 Scabies

Cysts

44 Epidermal Inclusion Cyst

45 Dermoid Cyst

Bone and Joint

Congenital/Genetic/Hereditary

46 Osteogenesis Imperfecta

47 Thanatophoric Dysplasia

Trauma/Injury/Reactive

48 Bone Fracture and Repair

49 Osteomyelitis

51 Stress and the Costochondral Junction

52 Juvenile Idiopathic Arthritis

Skeletal Muscle

Congenital/Genetic Hereditary

53 Spinal Muscular Atrophy

54 X-linked Muscular Dystrophy: Duchenne and Becker

Central Nervous System

Congenital/Genetic/Hereditary

55 Cerebral Heterotopia and Ectopia

56 Cortical Dysplasia

57 Encephalocele

58 Myelomeningocele

59 Tethered Cord

60 Arteriovenous Malformation

61 Carvernous Hemangioma

Trauma/Injury/Reactive

63 Hypoxic Ischemic Encephalopathy

64 Periventricular Leukomalacia

65 Arachnoid Cysts

66 Meningioangiomatosis

67 Germinal Matrix Hemorrhage

Infectious

68 Bacterial Meningoencephalitis

69 Fungal Meningoencephalitis

70 Viral Meningoencephalitis

71 Protozoal Meningoencephalitis

Endocrine System

Congenital/Genetic/Hereditary

72 Adrenal Cytomegaly

73 Adrenal Heterotopia

74 Adrenal Hypoplasia and Malformations

75 Adrenal Cortical Hyperplasia

76 Dyshormonogenetic Goiter

77 Ectopic Thyroid

78 Thyroglossal Duct Cyst

79 "Cystic Fibrosis, Pancreas"

Trauma/Injury/Reactive

80 Stress Reactions in the Adrenal Gland

81 Hemorrhagic Necrosis of the Adrenal Gland

82 Chronic Lymphocytic Thyroiditis

83 Graves Disease

84 Hypertrophy of Pancreatic Islets

Respiratory

Congenital/Genetic/Hereditary

85 Bronchogenic Cyst

86 Congenital Alveolar Capillary Dysplasia

87 Congenital Lobar Emphysema

88 Congenital Pulmonary Lymphangiectasis

89 Diffuse Pulmonary Lymphangiomatosis

90 Congenital Pulmonary Airway Malformation

91 Congenital Surfactant Deficiency

92 Cystic Fibrosis

93 Sequestrations

Trauma/Injury/Reactive

94 Aspiration

95 Asthma

96 Bronchopulmonary Dysplasia

97 Hyaline Membrane Disease

98 Interstitial Pulmonary Emphysema

99 Persistent Pulmonary Hypertension

100 Idiopathic Pulmonary Hemosiderosis

101 Pulmonary Venoocclusive Disease

102 Nonspecific Interstitial Pneumonia

103 Extrinsic Allergic Alveolitis

104 Eosinophilic Pneumonia

Infectious

105 Adenovirus

106 Human Metapneumovirus

107 Respiratory Syncytial Virus

108 Neuroendocrine Cell Hyperplasia of Infancy

Cardiovascular

Congenital/Genetic/Hereditary

109 Arrhythmogenic Right Ventricular Dysplasia

110 Hypertrophic Cardiomyopathy

111 Dilated Cardiomyopathy

112 Fabry Disease

113 Fatty Acid Metabolic Disorders

114 Glycogen Storage Disease

115 Mitochondrial Myopathies

Trauma/Injury/Reactive

116 Endocardial Fibroelastosis

Infectious

117 Lymphocytic Myocarditis

118 Acute Pericarditis

119 Acute Rheumatic Fever

120 Kawasaki Disease

Alimentary Canal

Esophagus

Congenital/Genetic/Hereditary

121 Inlet Patch

122 Tracheoesophageal Fistula/Esophageal Atresia

123 Esophageal Duplication Cyst

Trauma/Injury/Reactive

124 Gastroesophageal Reflux Disease

125 Eosinophilic Esophagitis

Infectious

126 Herpes Simplex Virus

127 Candida

Stomach

Trauma/Injury/Reactive

128 Chemical (Reactive) Gastropathies

129 Chronic Gastritis

130 Granulomatous Gastritis

131 Lymphocytic Gastritis

132 Eosinophilic Gastroenteritis

133 Fundic Gland Polyp

Infectious

134 Helicobacter Pylori

135 Helicobacter Heilmannii

Small Bowel

Congenital/Genetic/Hereditary

136 Small Intestine Duplication Cyst

137 Ectopic Pancreas

138 Gastric Heterotopia

139 Meckel Diverticulum

140 Microvillous Inclusion Disease

141 Primary Intestinal Lymphangiectasia

142 Abetalipoproteinemia

143 Tufting Enteropathy

144 Autoimmune Enterocolitis

Inflammatory/Immune Dysfunction

145 Celiac Disease

146 Common Variable Immunodeficiency

Infectious

147 Giardia

148 Cryptosporidium

Appendix

149 Acute Appendicitis

150 Granulomatous Appendicitis

151 Enterobius Vermicularis Appendicitis

152 Fibrous Obliteration

Colon

Congenital/Genetic/Hereditary

153 "Cystic Fibrosis, Intestinal"

154 "Colonic Duplications, Cysts, and Congenital Diverticula"

155 Hirschsprung Disease

Trauma/Injury/Reactive

156 Diversion Colitis

157 Pneumatosis Intestinalis

158 Solitary Rectal Ulcer Syndrome/Mucosal Prolapse

159 Necrotizing Enterocolitis

Inflammatoyr/Immune Dysfunction

160 Eosinophilic/Allergic Colitis

161 Focal Active Colitis

162 Crohn Disease

163 Ulcerative Colitis

Infectious

164 Cytomegalovirus

165 Entamoeba Histolytica

166 Adenovirus

167 Acute Self-Limited Infectious Colitis

168 Pseudomembranous Colitis

Liver/Gallbladder

Congenital/Genetic/Hereditary

169 Congenital Hepatic Fibrosis

170 Caroli Disease

171 Cystic Fibrosis, Hepatic

172 Dubin-Johnson Syndrome

173 Gilbert Disease

174 Progressive Familial Intrahepatic Cholestasis

175 Biliary Atresia

176 Paucity of Intrahepatic Bile Ducts (Syndromic)

177 Paucity of Intrahepatic Bile Ducts (Nonsyndromic)

178 Autoimmune Hepatitis

179 Alpha-1-Antitrypsin Deficiency

180 Glycogen Storage Diseases

181 Niemann-Pick Disease

182 Tyrosinemia

183 Gaucher Disease

184 Neonatal Hemochromatosis

185 Wilson Disease

186 Choledochal Cyst

Trauma/Injury/Reactive

187 Total Parenteral Nutrition Injury

188 Idiopathic Neonatal Hepatitis

189 Reye Syndrome

190 NASH

191 Primary Sclerosing Cholangitis

192 Venooclusive Disease

193 Drug-Related Acute Hepatitis

Infectious

194 Acute Viral Hepatitis

195 Epstein-Barr Virus

196 Herpes Simplex Virus

197 Cytomegalovirus

Genitourinary

Kidney/Urinary Tract

Glomerular Diseases

198 Congenital Nephrotic Syndrome

199 Diffuse Mesangial Sclerosis

200 Minimal Change Disease

201 Focal Segmental Glomerulosclerosis

202 Acute Postinfectious Glomerulonephritis

203 Membranoproliferative Glomerulonephritis

204 C3 Glomerulonephritis

205 Dense Deposit Dense

206 Lupus Nephritis

207 IgA Nephropathy

208 Henoch-Schonlein Purpura Nephritis

209 Thin Basement Membrane Nephropathy

210 Alport Syndrome

Tubulointerstitial Disease

211 Acute Tubular Necrosis

212 Acute Pyelonephritis

213 Tubulointerstitial Nephritis

214 Primary Hyperoxaluria

Vascular Diseases

215 Fibromuscular Dysplasia (Renal Artery Stenosis)

216 "Hemolytic Uremic Syndrome, Infection-Related and Atypical"

217 "Vasculitis, ANCA-Related"

Cystic and Developmental Diseases

218 Reflux Nephropathy

219 "Polycystic Kidney Disease, Autosomal Recessive"

220 "Polycystic Kidney Disease, Autosomal Dominant"

221 Medullary Cystic Kidney Disease/Nephronophthisis

222 Renal Dysplasia

223 Renal Tubular Dysgenesis

224 Ask-Upmark Kidney

Reproductive System

Congenital/Genetic/Hereditary

225 Accessory Breast Tissue

226 Vaginal Adenosis

227 Cryptorchidism

228 Testicular Regression Syndrome

229 Gonadal Dysgenesis

Inflammatory/Immune Dysfunction

230 Hidradenitis Suppurativa

231 Childhood Beh�et Disease

Trauma/Injury/Reactive

232 Adnexal (Ovarian) Torsion

233 Meconium Periorchitis

234 Testicular Torsion

Miscellaneous

235 Ovarian Cysts

Hematopoietic

Lymph Nodes

Reactive Lymphadenopathies

236 Reactive Follicular Hyperplasia

237 Reactive Paracortical Hyperplasia

238 Progressive Transformation of Germinal Centers

239 Hyaline Vascular Castleman Disease

240 Dermatopathic Lymphadenitis

241 Kimura Disease

242 Rosai-Dorfman Disease

Infectious Lymphadenopathies

243 Infectious Mononucleosis Lymphadenitis

244 Cat Scratch Lymphadenitis

245 Mycobacterial Infections

246 Chronic Granulomatous Lymphadenitis

247 Toxoplasma Lymphadenitis

Blood and Bone Marrow

Congenital/Genetic/Hereditary

248 Chediak-Higashi Syndrome

249 Congenital Amegakaryocytic Thrombocytopenia

250 Congenital Thrombotic Thrombocytopenia Purprua

251 Congenital Erythrocytosis

252 Diamond-Blackfan Anemia

253 Hereditary Spherocytosis

254 Hereditary Elliptocytosis

255 Fanconi Anemia

256 Pyruvate Kinase Deficiency

257 Shwachman-Diamond Syndrome

258 Severe Congenital Neutropenia and Cyclic Neutropenia

259 Sickle Cell Anemia

260 Hemophagocytic Lymphohistiocytosis

261 Thalassemia

Infectious

262 Infectious Mononucleosis Syndromes

263 Parvo B-19 Infection

Miscellaneous

264 Transient Erythroblastopenia of Childhood

Thymus

Trauma/Injury/Reactive

265 Acute Thymic Involution

Authors

Angelica R. Putnam Associate Professor of Pathology, University of Utah School of Medicine, Division of Pediatric Pathology, Primary Children's Hospital, Salt Lake City, Utah. Karen S. Thompson Professor and Chair, Department of Pathology, John A. Burns School of Medicine, University of Hawaii, Pan Pacific Pathologists, Clinical Laboratories of Hawaii, Kapiolani Medical Center for Women and Children, Honolulu, Hawaii.