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Immunogenetics: A Molecular and Clinical Overview. Clinical Applications of Immunogenetics

  • Book

  • March 2022
  • Elsevier Science and Technology
  • ID: 5410282

Clinical Applications of Immunogenetics: Immunogenetics: A Molecular and Clinical Overview, Volume II provides readers with an exclusive, updated overview of scientific knowledge, achievements and findings in the field of immunogenetics. In thirteen chapters, the book gives insights in new advancements and approaches in viral and autoimmune diseases. Specific chapters are dedicated to immunogenetic mechanisms in the treatment of immune disorders, cancer, neurological and neurodegenerative disorders. In addition, other chapters cover immunogenomics in precision medicine, clinical medicine and transplantation. Finally, a special chapter, COVID-19: A novel challenge to human immune-genetic machinery, updates on thoughts surrounding the pandemic.

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Table of Contents

1. Immunogenetics: A significant determinant for understanding recurrent pregnancy losses
2. Type 1 diabetes: Current�immunogenetic�advancements
3. Immunogenetic approach in the understanding of human viral diseases
4. Immunogenetics: A tool for the identification of novel therapeutic targets in immune disorders
5. Immunogenetics mechanisms in the treatment of cancer
6. Immunogenomics: A potential approach for precision medicine
7. Immunogenetics in the diagnosis of clinical disorders
8. Novel insights in transplantation immunogenetics
9. Immunogenetic markers as prognostic tool of human diseases
10. COVID-19: A novel challenge to human immune-genetic machinery
11. HLA- typing: A significant immunogenetics application in clinical medicine
12 Immunogenetic mechanisms driving neurological and neurodegenerative disorders
13. Immunogenetics and its utility in therapeutics

Authors

Muneeb U Rehman College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Muneeb U Rehman (Ph.D.) is a Faculty member at College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. He holds a doctorate in Toxicology (specialization in cancer biology and natural product research) from Jamia Hamdard, New Delhi, India. Dr. Rehman has more than 10 years of research and teaching experience in the field of toxicology, cancer biology, natural product pharmacology and pharmacogenomics. He is the recipient of several national and international fellowships and awards. He has published more than 100 research papers in peer-reviewed, international journals, and has 5 edited books and 30 book chapters. Dr. Rehman is on the editorial boards and is a reviewer of several high-impact, international scientific journals. He is also a life member of various international societies and organizations. Currently, Dr. Rehman is engaged in studying the molecular mechanisms of cancer prevention by natural products and the role of pharmacogenomics and toxicogenomics in evaluating the effectiveness and safety of drugs. Azher Arafah Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Azher Arafah works in the Department of Clinical Pharmacy, College of Pharmacy at King Saud University in Riyadh, Saudi Arabia. Md. Niamat Ali Cytogenetics and Molecular Biology Laboratory, Centre of Research for Development, University of Kashmir, Srinagar, Jammu and Kashmir, India. Md. Niamat Ali (M. Phil, Ph.D.) is Director and Faculty member at Centre of Research for Development, University of Kashmir, Srinagar, India. After completing his doctorate in Zoology (Specialization in Cytogenetics and Molecular Biology), Aligarh Muslim University, Aligarh, India in 1994. He worked as Research Associate and Pool Officer (CSIR, New Delhi) at the Aligarh Muslim University, Aligarh, India till 2002. Later He joined Department of Zoology, University of Kashmir, Srinagar, India and worked there till 2013. Prof. Ali has more than 29 years of research experience and 25 years of teaching experience in Cytogenetics and Molecular Biology, Toxicogenomics, Human Genomics and Proteomics, Stem Cell Biology, Regenerative Medicine, Radiation Biology and Gene Therapy, Cell and Tissue Culture Technology and Ageing Biology, PCR and DNA Fingerprinting Technology, FISH Technology and Comet Assay and Biostatistics. He is the recipient of several fellowships and awards at both national and international levels. He is a Life Member of Indian Science Congress Association and Environmental Mutagen Society of India, India. Prof. Ali is handling many projects of national and international importance. He also has to his credit 65 research publications in peer-reviewed international journals and multiple book chapters in edited volumes with international publishers. Prof. Ali is on editorial board panel and reviewer of several high-impact international scientific journals from Springer, Elsevier and John Wiley. He also has served as Executive Editor of Journal/ Editor Souvenir and Abstract Book for Seminar and Conference/ Workshop Guide Books. Currently, Prof. Ali is involved in studying vermin-technology, eco-toxicology, fish toxicology, DNA bar-coding, cancer biology, congenital human diseases, immunogenetic mechanisms of Recurrent Pregnancy loss etc. Shafat Ali Cytogenetics and Molecular Biology Laboratory, Centre of Research for Development, University of Kashmir, Jammu and Kashmir, India. Shafat Ali (Ph.D.) pursued his BSc. from University of Kashmir and Masters in Zoology from Barkatullah Vishwavidyalaya, India. Currently he is engaged in research work for last 5 years at Cytogenetics and Molecular Biology Laboratory, Centre of Research for Development, University of Kashmir, Department of Biochemistry, Government Medical College, Srinagar, Jammu and Kashmir, and ICMR funded Multidisciplinary Research Unit, Government Medical College, Srinagar, Jammu and Kashmir, India, with specialization in the field of reproductive immunogenetics, cytokine biology, gynaecology and obstetrics, molecular biology, cancer biology and cytogenetics. He has 5 years of research experience and 5 years of teaching experience. He has more than 20 book chapters, several edited books and numerous peer-reviewed, international research publications to his credit. Mr. Ali is also the reviewer of many reputed international journals. Presently, Mr. Ali is involved in studying immunogenetic mechanisms involved in recurrent pregnancy loss