Next-generation sequencing refers to the deep, high-throughput, in-parallel DNA sequencing technologies developed a couple of decades after the Sanger DNA sequencing method first emerged in 1977. It is a massively parallel sequencing technology that offers scalability, ultra-high throughput, and high speed to determine the order of nucleotides in the entire genome. DNA pre-sequencing is one of the most significant steps in the overall sequencing protocol as it involves the preparation of the sample for the subsequent sequencing reaction. Further, the expansion of the worldwide next-generation sequencing market is majorly driven by a rise in genome mapping programs, a rise in applications of next-generation sequencing; an increase in healthcare expenditure; and technological advancements in sequencing platforms. According to the publisher, The Next Generation Sequencing Market will reach US$ 34.8 Billion by 2027.
Impact of COVID-19 Pandemic
The potential advantage of NGS diagnostic technology was to determining the genetic sequence of a virus and helping scientists understand the change of the virus. Throughout the COVID-19 pandemic, government authorities worldwide are constantly working with the private sector to bring NGS technology the potential diagnostic tool within the market. In 2020, the (US FDA) United States Food and Drug Administration issued an emergency use authorized (EUA) to Illumina Inc. for the first COVID-19 diagnostic test adopting NGS technology. The FDA approved the Illumina COVID Seq Test for the qualitative detection of SARS-CoV-2 RNA.
Based on Type
Next-Generation Sequencing Market includes Targeted Re-sequencing (TPS/WES), RNA-Sequencing, Whole Genome Sequencing, Chip-Sequencing, De Novo Sequencing, and Methyl-Sequencing. Targeted Re-sequencing holds the largest market share; the technology allows economic options for WGS (World Geodetic System) and facilitates the in-depth study of genomic regions. RNA-based targeted sequencing is expected to witness lucrative growth in the coming years due to the growing demand for differential expression analysis. As per this report, the Next-generation Sequencing Industry will grow with a CAGR of 22.94% during2020 - 2027.
Moreover, in recent years, NGS has been considered the most potent tool in diagnostics and research to understand the treatment regimen for various diseases, including cancer, infectious diseases and cardiovascular diseases. In cancer diagnostics, due to the widespread adoption of liquid biopsies, there has been a significant increase in the utilization of NGS technologies. These technologies utilize cell-free circulating tumour DNA (ctDNA) as a non-invasive cancer biomarker for real-time cancer monitoring and detection.
NGS is steadily being integrated into user verticals like Academic and Research Institutes, Biopharmaceutical Industry, Diagnostics Industry, Governments Agencies, Hospitals and Clinics. The academic and Biopharmaceutical Industry dominates the NGS industry. Academic created the most significant revenue to the high usage of the next-generation sequencing platforms for basic research programs within universities and institutes. As per this study, Next-generation sequencing Market Size was US$ 8.2 Billion in 2020.
In addition, Next-generation sequencing informatics Services are used in clinical applications of NGS, technological advancements in NGS informatics tools, growing preference toward personalized medicines and early disease diagnosis, and the increasing demand for NGS services and investments by key companies.
The key players include Illumina, Thermo Fisher Scientific, Pacific Biosciences, Oxford Nanopore Technologies, and Roche. They were operating in the global next-generation sequencing market. In 2020, Illumina Inc. acquired GRAIL, a healthcare company focused on multi-cancer early detection, for cash and stock consideration of US$ 8 Billion upon closing of the transaction.
This latest report “Next-generation sequencing Market by Types of Test (Targeted Re-sequencing (TPS/WES), RNA-Sequencing, Whole Genome Sequencing, ChIP-Sequencing, De Novo Sequencing, and Methyl-Sequencing) by Disease (Reproductive Health NGS test, NGS Test Market (Rare Disease Diagnostics), Cancer (Risk Prediction, therapy Selection & Response), Metabolic Immune (Diagnostic), Cardiovascular NGS Test Market, Others NGS Test Market) by Informatics (NGS Informatics Services, Primary and Secondary Data Analysis Tools, Computing, Storage, Biological Interpretation and Reporting Tools, LIMS (Laboratory Information Management System) by End User (Academic and Research Institutes, Biopharmaceutical Industry, Diagnostics Industry, Governments Agencies, Hospitals and Clinics); provides a detailed analysis of Next-generation sequencing Industry.
Types of Test - Next Generation Sequencing Market have been covered from 6 viewpoints:
1. Targeted Re-sequencing (TPS/WES)
2. RNA-Sequencing
3. Whole Genome Sequencing
4. ChIP-Sequencing
5. De Novo Sequencing
6. Methyl-Sequencing
Disease - Global Next Generation Sequencing Test Market have been covered from 6 viewpoints:
1. Reproductive Health NGS test
2. NGS Test Market (Rare Disease Diagnostics)
3. Cancer (Risk Prediction, therapy Selection & Response)
4. Metabolic Immune (Diagnostic)
5. Cardiovascular NGS Test Market
6. Others NGS Test Market
Informatics - Global Next Generation Sequencing Market have been covered from 6 viewpoints:
1. NGS Informatics Services
2. Primary and Secondary Data Analysis Tools
3. Storage
4. Computing
5. Biological Interpretation and Reporting Tools
6. LIMS (Laboratory Information Management System)
End User - Global Next Generation Sequencing Market have been covered from 5 viewpoints:
1. Academic and Research Institutes
2. Biopharmaceutical Industry
3. Diagnostics Industry
4. Governments Agencies
5. Hospitals and Clinics
Company Insights:
- Overview
- Recent Development
Companies Covered:
1. Illumina
2. Thermo Fisher Scientific
3. Pacific Biosciences
4. Oxford Nanopore Technologies
5. Roche
What is the estimated value of the Global Next Generation Sequencing Market?
What is the growth rate of the Global Next Generation Sequencing Market?
What is the forecasted size of the Global Next Generation Sequencing Market?
Who are the key companies in the Global Next Generation Sequencing Market?
| Report Attribute | Details |
|---|---|
| No. of Pages | 135 |
| Published | August 2021 |
| Forecast Period | 2020 - 2027 |
| Estimated Market Value ( USD | $ 8.2 Billion |
| Forecasted Market Value ( USD | $ 34.8 Billion |
| Compound Annual Growth Rate | 22.9% |
| Regions Covered | Global |
| No. of Companies Mentioned | 5 |
Table of Contents
1. Introduction2. Research Methodology3. Executive Summary
Companies Mentioned
- Illumina
- Thermo Fisher Scientific
- Pacific Biosciences
- Oxford Nanopore Technologies
- Roche
Methodology
In this report, for analyzing the future trends for the studied market during the forecast period, the publisher has incorporated rigorous statistical and econometric methods, further scrutinized by secondary, primary sources and by in-house experts, supported through their extensive data intelligence repository. The market is studied holistically from both demand and supply-side perspectives. This is carried out to analyze both end-user and producer behavior patterns, in the review period, which affects price, demand and consumption trends. As the study demands to analyze the long-term nature of the market, the identification of factors influencing the market is based on the fundamentality of the study market.
Through secondary and primary researches, which largely include interviews with industry participants, reliable statistics, and regional intelligence, are identified and are transformed to quantitative data through data extraction, and further applied for inferential purposes. The publisher's in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. These analytical tools and models sanitize the data & statistics and enhance the accuracy of their recommendations and advice.
Primary Research
The primary purpose of this phase is to extract qualitative information regarding the market from the key industry leaders. The primary research efforts include reaching out to participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions. The publisher also established professional corporate relations with various companies that allow us greater flexibility for reaching out to industry participants and commentators for interviews and discussions, fulfilling the following functions:
- Validates and improves the data quality and strengthens research proceeds
- Further develop the analyst team’s market understanding and expertise
- Supplies authentic information about market size, share, growth, and forecast
The researcher's primary research interview and discussion panels are typically composed of the most experienced industry members. These participants include, however, are not limited to:
- Chief executives and VPs of leading corporations specific to the industry
- Product and sales managers or country heads; channel partners and top level distributors; banking, investment, and valuation experts
- Key opinion leaders (KOLs)
Secondary Research
The publisher refers to a broad array of industry sources for their secondary research, which typically includes, however, is not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Patent and regulatory databases for understanding of technical & legal developments
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic new articles, webcasts, and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecasts
LOADING...
