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Oligonucleotides: Global Markets to 2026

  • ID: 5412098
  • Report
  • August 2021
  • Region: Global
  • 88 Pages
  • BCC Research

FEATURED COMPANIES

  • Agilent Technologies Inc.
  • Biolegio B.V.
  • Customarray Inc.
  • Eurofins Scientific
  • LC Sciences Llc
  • LGC Ltd.

The global market for oligonucleotide synthesis should grow from $6.1 billion in 2021 to $10.2 billion by 2026 with a compound annual growth rate (CAGR) of 10.7% for the period of 2021-2026.

The oligonucleotide drugs market should grow from $4.3 billion in 2021 to $7.2 billion by 2026 with a compound annual growth rate (CAGR) of 11.0% for the period of 2021-2026.

The synthesized oligos market should grow from $1.1 billion in 2021 to $1.7 billion by 2026 with a compound annual growth rate (CAGR) of 9.6% for the period of 2021-2026.

Report Scope

This report covers the worldwide market for oligonucleotide synthesis, which consists of four main product types: oligonucleotide drugs, synthesized oligos, equipment and reagents, and services. Based on application, the market for oligonucleotide synthesis is divided into research and diagnostics and therapeutics.

By geography, the market in this report is divided into four regions: North America, Europe, Asia-Pacific, and Rest of the World (RoW). The report includes detailed analyses of the major countries in these regions. For market estimates, data has been provided for 2020 as the base year, with forecasts for 2021 through 2026.

The report also covers approved drugs, the oligonucleotide synthesis process, innovative research, opportunities within the market and profiles of leading companies in the oligonucleotide synthesis industry.

The Report Includes

  • 22 data tables and 20 additional tables
  • An overview of the global market for oligonucleotides
  • Estimation of the market size and analyses of global market trends, with data from 2019, 2020, estimates for 2021 and projections of compound annual growth rates (CAGRs) through 2026
  • Evaluation of current market trends, and technological advancements within the industry and market share analysis of oligonucleotides by type, application, and region
  • Information on the classifications and applications of oligonucleotides and detailed description of DNA oligos and RNA oligos synthesis
  • Details of solid-phase chemical synthesis and alternative forms of oligonucleotide synthesis processes and insights into government regulations for oligonucleotide-based drugs
  • Information on CRISPR-Cas diagnosis and therapeutic tools for SARS-CoV-2 infection, and discussion on ASO as a COVID-19 therapeutic
  • A look at the new product developments, clinical trials, patents, mergers and acquisitions and collaborations or partnership of the industry
  • Company profiles of major players of the industry, including Agilent Technologies , Eurofins Scientific, Biolegio, Merck KGaA , Integrated DNA Technologies and Thermo Fisher Scientific
Note: Product cover images may vary from those shown

FEATURED COMPANIES

  • Agilent Technologies Inc.
  • Biolegio B.V.
  • Customarray Inc.
  • Eurofins Scientific
  • LC Sciences Llc
  • LGC Ltd.

Chapter 1 Introduction

  • Study Goals and Objectives
  • Reasons for Doing this Study
  • Scope of Report
  • Information Sources
  • Methodology
  • Intended Audience
  • Geographic Breakdown
  • Analyst's Credentials
  • Custom Research
  • Related Reports

Chapter 2 Summary and Highlights

  • Market Size and Projected Growth

Chapter 3 Market Overview

  • Definitions
  • History of Oligonucleotide Synthesis
  • First Dinucleotide
  • Solid Phase Synthesis
  • Types of Oligonucleotides
  • DNA Probes
  • RNA Probes
  • Oligonucleotide Synthesis Process
  • Solid Phase Chemical Synthesis
  • Alternative Forms of Oligonucleotide Synthesis
  • Market Dynamics
  • Drivers
  • Restraints
  • Opportunities

Chapter 4 Impact of COVID-19 on the Market

  • Overview
  • Current Outlook
  • Impact of COVID-19 on the Market for Oligonucleotide Synthesis
  • CRISPR-Cas Diagnosis and Therapeutic Tools for SARS-CoV-2
  • ASO as a COVID-19 Therapeutic
  • Nucleic Acid Hybridization Using Microarray Process

Chapter 5 Market Breakdown by Product Type

  • Overview
  • Oligonucleotide Drugs
  • Market Size and Forecast
  • Market Analysis
  • Equipment and Reagents
  • Market Size and Forecast
  • Market Analysis
  • Synthesized Oligos
  • Market Size and Forecast
  • Market Analysis
  • Services
  • Market Size and Forecast
  • Market Analysis

Chapter 6 Market Breakdown by Application

  • Overview
  • Research
  • Market Size and Forecast
  • Market Analysis
  • Diagnostics and Therapeutics
  • Market Size and Forecast
  • Market Analysis

Chapter 7 Market Breakdown by Region

  • Introduction
  • North America
  • U.S.
  • Canada
  • Europe
  • Germany
  • U.K.
  • France
  • Italy
  • Spain
  • Rest of Europe
  • Asia-Pacific
  • China
  • India
  • Japan
  • Rest of Asia-Pacific
  • Rest of the World

Chapter 8 Industry Structure

  • Competitive Landscape

Chapter 9 Company Profiles

  • Agilent Technologies Inc.
  • Biolegio B.V.
  • Biolytic Lab Performance Inc.
  • Customarray Inc.
  • Eurofins Scientific
  • Integrated Dna Technologies Inc. (Danaher)
  • LC Sciences Llc
  • LGC Ltd.
  • Merck Kgaa
  • Microsynth Ag
  • Thermo Fisher Scientific Inc.

Chapter 10 Appendix: Acronyms

List of Tables
Summary Table: Global Market for Oligonucleotide Synthesis, by Product Type, Through 2026
Table 1: History of Oligonucleotide Therapeutics
Table 2: Comparison of Oligonucleotide and Polynucleotide
Table 3: Yield, Length and Coupling Efficiency of Oligonucleotide
Table 4: List of Approved Oligonucleotide Therapeutics
Table 5: Reported Coronavirus Cases and Deaths, by Country
Table 6: Global Market for Oligonucleotide Synthesis, by Product Type, Through 2026
Table 7: Global Market for Oligonucleotide Drugs, by Region, Through 2026
Table 8: Global Market for Equipment and Reagents, by Region, Through 2026
Table 9: Global Market for Synthesized Oligos, by Region, Through 2026
Table 10: Pricing of Oligo Pools, by Twist Bioscience
Table 11: Pricing for Oligo pools, by GenScript
Table 12: Global Market for Services, by Region, Through 2026
Table 13: Global Market for Oligonucleotide Synthesis, by Application, Through 2026
Table 14: Global Market for Research Applications, by Region, Through 2026
Table 15: Global Market for Diagnostic and Therapeutic Applications, by Region, Through 2026
Table 16: Global Market for Oligonucleotide Synthesis, by Region, Through 2026
Table 17: North American Market for Oligonucleotide Synthesis, by Product Type, Through 2026
Table 18: North American Market for Oligonucleotide Synthesis, by Application, Through 2026
Table 19: North American Market for Oligonucleotide Synthesis, by Country, Through 2026
Table 20: European Market for Oligonucleotide Synthesis, by Product Type, Through 2026
Table 21: European Market for Oligonucleotide Synthesis, by Application, Through 2026
Table 22: European Market for Oligonucleotide Synthesis, by Country, Through 2026
Table 23: Asia-Pacific Market for Oligonucleotide Synthesis, by Product Type, Through 2026
Table 24: Asia-Pacific Market for Oligonucleotide Synthesis, by Application, Through 2026
Table 25: Asia-Pacific Market for Oligonucleotide Synthesis, by Country, Through 2026
Table 26: RoW Market for Oligonucleotide Synthesis, by Product Type, Through 2026
Table 27: RoW Market for Oligonucleotide Synthesis, by Application, Through 2026
Table 28: Oligonucleotide Therapeutics in Clinical Trials for Oncology
Table 29: Company Sales Revenue of Oligonucleotide Drugs, 2020
Table 30: Agilent Technologies: Products and Services
Table 31: Biolegio: Products and Services
Table 32: Biolytic Lab Performance: Products and Services
Table 33: CustomArray: Products and Services
Table 34: Eurofins Scientific: Products and Services
Table 35: Integrated DNA Technologies: Products and Services
Table 36: LC Sciences: Products and Services
Table 37: LGC Ltd.: Products and Services
Table 38: Merck KGaA: Products and Services
Table 39: Microsynth AG: Products and Services
Table 40: Thermo Fisher Scientific: Products and Services
Table 41: Acronyms Used in this Report

List of Figures
Summary Figure: Global Market Shares of Oligonucleotide Synthesis, by Product Type, 2020
Figure 1: Global Market Shares of Oligonucleotide Synthesis, by Product Type, 2020
Figure 2: Global Market for Oligonucleotide Drugs, 2019-2026
Figure 3: Global Market for Oligonucleotide Drugs, by Region, 2019-2026
Figure 4: Global Market for Equipment and Reagents, 2019-2026
Figure 5: Global Market for Equipment and Reagents, by Region, 2019-2026
Figure 6: Global Market for Synthesized Oligos, 2019-2026
Figure 7: Global Market for Synthesized Oligos, by Region, 2019-2026
Figure 8: Global Market for Services, 2019-2026
Figure 9: Global Market for Services, by Region, 2019-2026
Figure 10: Global Market Shares of Oligonucleotide Synthesis, by Application, 2020
Figure 11: Global Market for Research Applications, 2019-2026
Figure 12: Global Market for Research Applications, by Region, 2019-2026
Figure 13: Global Market for Diagnostic and Therapeutic Applications, 2019-2026
Figure 14: Global Market for Diagnostics and Therapeutics, by Region, 2019-2026
Figure 15: Global Market for Oligonucleotide Synthesis, by Region, 2019-2026
Figure 16: North American Market Shares of Oligonucleotide Synthesis, by Product Type, 2020
Figure 17: North American Market Shares of Oligonucleotide Synthesis, by Application, 2020
Figure 18: North American Market Shares of Oligonucleotide Synthesis, by Country, 2020
Figure 19: U.S. Market for Oligonucleotide Synthesis, 2019-2026
Figure 20: Canadian Market for Oligonucleotide Synthesis, 2019-2026
Figure 21: European Market Shares of Oligonucleotide Synthesis, by Product Type, 2020
Figure 22: European Market Shares of Oligonucleotide Synthesis, by Application, 2020
Figure 23: European Market Shares of Oligonucleotide Synthesis, by Country, 2020
Figure 24: German Market for Oligonucleotide Synthesis, 2019-2026
Figure 25: U.K. Market for Oligonucleotide Synthesis, 2019-2026
Figure 26: French Market for Oligonucleotide Synthesis, 2019-2026
Figure 27: Italian Market for Oligonucleotide Synthesis, 2019-2026
Figure 28: Spanish Market for Oligonucleotide Synthesis, 2019-2026
Figure 29: Rest of European Market for Oligonucleotide Synthesis, 2019-2026
Figure 30: Asia-Pacific Market Shares of Oligonucleotide Synthesis, by Product Type, 2020
Figure 31: Asia-Pacific Market Shares of Oligonucleotide Synthesis, by Application, 2020
Figure 32: Asia-Pacific Market Shares of Oligonucleotide Synthesis, by Country, 2020
Figure 33: Chinese Market for Oligonucleotide Synthesis, 2019-2026
Figure 34: Indian Market for Oligonucleotide Synthesis, 2019-2026
Figure 35: Japanese Market for Oligonucleotide Synthesis, 2019-2026
Figure 36: Rest of Asia-Pacific Market for Oligonucleotide Synthesis, 2019-2026
Figure 37: RoW Market Shares of Oligonucleotide Synthesis, by Product Type, 2020
Figure 38: RoW Market Shares of Oligonucleotide Synthesis, by Application, 2020
Figure 39: Agilent Technologies: Annual Revenue, 2018-2020
Figure 40: Agilent Technologies: Revenue Shares, by Segment, 2020
Figure 41: Agilent Technologies: Revenue Shares, by Region, 2020
Figure 42: Eurofins Scientific: Annual Revenue, 2018-2020
Figure 43: Eurofins Scientific: Revenue Share, by Region, 2020
Figure 44: Merck KGaA: Annual Revenue, 2018-2020
Figure 45: Merck KGaA: Revenue Share, by Business Segment, 2020
Figure 46: Merck KGaA: Revenue Share, by Region, 2020
Figure 47: Thermo Fisher Scientific: Annual Revenue, 2018-2020
Figure 48: Thermo Fisher Scientific: Revenue Share, by Business Segment, 2020
Figure 49: Thermo Fisher Scientific: Revenue Shares, by Region, 2020

Note: Product cover images may vary from those shown

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FEATURED COMPANIES

  • Agilent Technologies Inc.
  • Biolegio B.V.
  • Customarray Inc.
  • Eurofins Scientific
  • LC Sciences Llc
  • LGC Ltd.

The term oligonucleotide is derived from the Greek word oligo, which means small or few. The base length of the oligos is usually identified as “mer,” which means “part” in the Greek language.

Oligonucleotides are short DNA/RNA strands. These can be made based on client requirements by solid-phase chemical synthesis. They are made up of 13 to 25 bases to hybridize to a complementary sequence.

These oligos are primarily used in polymerase chain reaction (PCR) as a probe but are also used in DNA-based microarray techniques, Southern blot assay, FISH (Fluorescent In Situ Hybridization), and ASO analysis.

Along with its diagnostics and research uses, oligonucleotides are also being used as therapeutic drugs for a wide range of diseases. This type of drug focuses on the gene-silencing technique, as well as splice modulation and gene activation modalities for treatment. Oligonucleotide drugs offer personalized medicine approaches to target the specific gene sequences responsible for the occurrence of a specific disease. The first approved oligonucleotide drug was Vitravene (fomivirsen) in 1998 for the treatment of cytomegalovirus retinitis (CMV). To date, more than 14 drugs have received FDA approval for therapeutic usage for the treatment of liver, spinal cord and skeletal muscle-based disorders. For oncology treatment, more than 200 oligonucleotide drugs are in various phases of clinical trials.

Note: Product cover images may vary from those shown
  • Agilent Technologies Inc.
  • Biolegio B.V.
  • Biolytic Lab Performance Inc.
  • Customarray Inc.
  • Eurofins Scientific
  • Integrated Dna Technologies Inc. (Danaher)
  • LC Sciences Llc
  • LGC Ltd.
  • Merck Kgaa
  • Microsynth Ag
  • Thermo Fisher Scientific Inc.
Note: Product cover images may vary from those shown
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