The global prime editing and CRISPR market was valued at $2,694.2 million in 2020, and is estimated to reach $23,493.0 million by 2030, growing at a CAGR of 24.3% from 2021 to 2030.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology is a genetic tool used for editing of genome. Prime editing is considered as the developed version of CRISPR/Cas9 genome editing technology. It is a genome editing technology, which uses fusion protein of Cas9-nickase and reverse transcriptase for treatment of genetic defects. It is a new molecular gadget capable of removing and cutting any base pair and adding long segments of DNA without breaking both strands of the helix. Prime editing and CRISPR are used as molecular scissors to develop new therapies for treatment of chronic and genetic diseases. This technology helps in the treatment of rare genetic disease such as sickle cell anemia, cystic fibrosis, correction in point mutation and chronic disease such as lung cancer.
The global prime editing and CRISPR market is majorly driven by an alarming increase in prevalence of genomic and chronic diseases such as sickle cell anemia, cystic fibrosis and lung cancer; rise in government funds for genomic projects; surge in demand for genetically mutated crops; advancements in R&D of genes; and rise in awareness regarding genetic engineering. For instance, according to the World Health Organizations (WHO), in 2020, approximately, 10 million people dieddue to various types of cancer. As per data published by a Cystic fibrosis foundation (Cff), in 2019, a total of 70,000 population in the world was diagnosed with cystic fibrosis and more than 1000 new cases of cystic fibrosis were reported each year. Moreover, surge in demand for genetic engineering in biomedical research and rise in need for gene editing drive growth of the market. Thus, increase in prevalence of genetic-based disease and surge in demand for gene manipulation are the factors expected to propel growth of the market.
Rise in funding from private & government organizations to genomic project and increase in application in genetically mutated crops are the major factors that drive the growth of the global prime editing and CRISPR market. Moreover, surge in incidences of diseases such as cancer significantly contributes toward the market growth, owing to the fact that gene insertion and deletion technique is used in treatment of several chronic diseases. Rise in genomic research activities acts as a key driving force of the global market. Furthermore, governments are taking multiple initiatives to support regenerative medical research, which is expected to boost the market growth. Moreover, in 2021, SingHealth Duke-NUS Academic Medical Centre launched advanced regenerative medicine and introduced cellular therapy to enhance patient care. The project aims to explore regenerative cell therapy for treatment of blood cancers, heart failure, and eye degeneration. On the contrary, advancements in R&D for genetic engineering technology in emerging nations are anticipated to provide lucrative opportunities for the market expansion. For instance, in 2021, Scientist at US San Francisco, UC Berkeley launched first clinical trial of CRISPR gene correction therapy in patients suffering from sickle cell disease.
On the contrary, lack of safety concerns and ethical issues regarding gene editing in human germline are the factors anticipated to hinder the market growth during the forecast period. Decrease in cost of DNA is sequenced, which leads to enhancement of genomic research project and increase in research expenditure. This encourages many key players to enter emerging markets, thus offering a lucrative growth opportunity for the prime editing and CRISPR market.
The global prime editing and CRISPR market is segmented into service, application, end user, and region. By service, the market is categorized into cell line engineering, genome regulation, gene editing and gene-modified cell therapy. By application, it is divided into biomedical research & therapy, agricultural research, and others. By end user, the market is bifurcated into academic institutions, biotechnology & pharma companies, and contract research organizations. Region wise, it is analyzed across North America, Europe, Asia-Pacific, and LAMEA.
Some of the major companies that operate in the global prime editing and CRISPR market are Beam Therapeutics, CRISPR Therapeutics, GenScript Biotech, Horizon Discovery, Integrated DNA Technologies (IDT), Intellia Therapeutics Inc., Inscripta, Precision Bioscience, Sangoma Therapeutics, and Synthego Corporation.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology is a genetic tool used for editing of genome. Prime editing is considered as the developed version of CRISPR/Cas9 genome editing technology. It is a genome editing technology, which uses fusion protein of Cas9-nickase and reverse transcriptase for treatment of genetic defects. It is a new molecular gadget capable of removing and cutting any base pair and adding long segments of DNA without breaking both strands of the helix. Prime editing and CRISPR are used as molecular scissors to develop new therapies for treatment of chronic and genetic diseases. This technology helps in the treatment of rare genetic disease such as sickle cell anemia, cystic fibrosis, correction in point mutation and chronic disease such as lung cancer.
The global prime editing and CRISPR market is majorly driven by an alarming increase in prevalence of genomic and chronic diseases such as sickle cell anemia, cystic fibrosis and lung cancer; rise in government funds for genomic projects; surge in demand for genetically mutated crops; advancements in R&D of genes; and rise in awareness regarding genetic engineering. For instance, according to the World Health Organizations (WHO), in 2020, approximately, 10 million people dieddue to various types of cancer. As per data published by a Cystic fibrosis foundation (Cff), in 2019, a total of 70,000 population in the world was diagnosed with cystic fibrosis and more than 1000 new cases of cystic fibrosis were reported each year. Moreover, surge in demand for genetic engineering in biomedical research and rise in need for gene editing drive growth of the market. Thus, increase in prevalence of genetic-based disease and surge in demand for gene manipulation are the factors expected to propel growth of the market.
Rise in funding from private & government organizations to genomic project and increase in application in genetically mutated crops are the major factors that drive the growth of the global prime editing and CRISPR market. Moreover, surge in incidences of diseases such as cancer significantly contributes toward the market growth, owing to the fact that gene insertion and deletion technique is used in treatment of several chronic diseases. Rise in genomic research activities acts as a key driving force of the global market. Furthermore, governments are taking multiple initiatives to support regenerative medical research, which is expected to boost the market growth. Moreover, in 2021, SingHealth Duke-NUS Academic Medical Centre launched advanced regenerative medicine and introduced cellular therapy to enhance patient care. The project aims to explore regenerative cell therapy for treatment of blood cancers, heart failure, and eye degeneration. On the contrary, advancements in R&D for genetic engineering technology in emerging nations are anticipated to provide lucrative opportunities for the market expansion. For instance, in 2021, Scientist at US San Francisco, UC Berkeley launched first clinical trial of CRISPR gene correction therapy in patients suffering from sickle cell disease.
On the contrary, lack of safety concerns and ethical issues regarding gene editing in human germline are the factors anticipated to hinder the market growth during the forecast period. Decrease in cost of DNA is sequenced, which leads to enhancement of genomic research project and increase in research expenditure. This encourages many key players to enter emerging markets, thus offering a lucrative growth opportunity for the prime editing and CRISPR market.
The global prime editing and CRISPR market is segmented into service, application, end user, and region. By service, the market is categorized into cell line engineering, genome regulation, gene editing and gene-modified cell therapy. By application, it is divided into biomedical research & therapy, agricultural research, and others. By end user, the market is bifurcated into academic institutions, biotechnology & pharma companies, and contract research organizations. Region wise, it is analyzed across North America, Europe, Asia-Pacific, and LAMEA.
Some of the major companies that operate in the global prime editing and CRISPR market are Beam Therapeutics, CRISPR Therapeutics, GenScript Biotech, Horizon Discovery, Integrated DNA Technologies (IDT), Intellia Therapeutics Inc., Inscripta, Precision Bioscience, Sangoma Therapeutics, and Synthego Corporation.
Key benefits for stakeholders
- The report provides an in-depth analysis of the global prime editing and CRISPR market size along with the current trends and future estimations to elucidate the imminent investment pockets.
- It offers market analysis from 2021 to 2030, which is expected to enable the stakeholders to capitalize on the prevailing opportunities in the market.
- A comprehensive analysis on region assists to understand the regional market and facilitate the strategic business planning and determine prevailing opportunities.
- The profiles and growth strategies of the key players are thoroughly analyzed to understand the competitive outlook of the global prime editing and CRISPR market.
KEY MARKET SEGMENTS
By Service
- Cell Line Engineering
- Genome Regulation
- Gene Editing
- Gene-Modified Cell Therapy
By Application
- Biomedical Research & Therapy
- Agricultural Research
- Others
By End User
- Academic Institutes
- Biomedical Research & Therapy
- Agricultural Research
- Others
- Biotechnology & Pharma Companies
- Biomedical Research & Therapy
- Agricultural Research
- Others
- Contract Research Organizations
- Biomedical Research & Therapy
- Agricultural Research
- Others
By Region
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- UK
- Italy
- Spain
- Rest of Europe
- Asia-Pacific
- Japan
- China
- Australia
- India
- South Korea
- Rest of Asia-Pacific
- LAMEA
- Brazil
- Saudi Arabia
- South Africa
- Rest of LAMEA
KEY MARKET PLAYERS
- Beam Therapeutics
- CRISPR Therapeutics
- GenScript Biotech
- Horizon Discovery
- Integrated DNA Technologies (IDT
- Intellia Therapeutics Inc.,
- Inscripta
- Precision Bioscience
- Sangoma Therapeutics
- Synthego Corporation
Table of Contents
CHAPTER 1: INTRODUCTION
CHAPTER 2: EXECUTIVE SUMMARY
CHAPTER 3: MARKET LANDSCAPE
CHAPTER 4: PRIME EDITING AND CRISPR MARKET, BY SERVICE
CHAPTER 5: PRIME EDITING AND CRISPR MARKET, BY APPLICATION
CHAPTER 6: PRIME EDITING AND CRISPR MARKET, BY END USER
CHAPTER 7: PRIME EDITING AND CRISPR MARKET, BY REGION
CHAPTER 8: COMPANY PROFILES
List of Tables
List of Figures
Companies Mentioned
- Beam Therapeutics
- CRISPR Therapeutics
- GenScript Biotech
- Horizon Discovery
- Integrated DNA Technologies (IDT)
- Intellia Therapeutics Inc.
- Inscripta
- Precision Bioscience
- Sangoma Therapeutics
- Synthego Corporation.
Methodology
The analyst offers exhaustive research and analysis based on a wide variety of factual inputs, which largely include interviews with industry participants, reliable statistics, and regional intelligence. The in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. The primary research efforts include reaching out participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions.
They are also in professional corporate relations with various companies that allow them greater flexibility for reaching out to industry participants and commentators for interviews and discussions.
They also refer to a broad array of industry sources for their secondary research, which typically include; however, not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic news articles and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecast
Furthermore, the accuracy of the data will be analyzed and validated by conducting additional primaries with various industry experts and KOLs. They also provide robust post-sales support to clients.
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Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 271 |
| Published | June 2021 |
| Forecast Period | 2020 - 2030 |
| Estimated Market Value ( USD | $ 2694.2 million |
| Forecasted Market Value ( USD | $ 23493 million |
| Compound Annual Growth Rate | 24.2% |
| Regions Covered | Global |
| No. of Companies Mentioned | 10 |
