The global viscosupplementation market size was estimated at USD 5.30 billion in 2024 and is projected to reach USD 9.39 billion by 2033, growing at a CAGR of 6.21% from 2025 to 2033. Viscosupplementation aims to alleviate joint pain and enhance the functional state of the knee.
The growing incidence of osteoarthritis plays a significant role in driving the demand for viscosupplementation. Osteoarthritis, a chronic degenerative joint disease, is the primary cause of enduring disability. It typically emerges after the age of 30 and can progress to a disabling condition within a decade of diagnosis. In March 2025, an article published in Scientific Reports analyzed osteoarthritis data from the Global Burden of Disease Study 2021. The study reported a sharp rise in global OA incidence from 20.9 million cases in 1990 to 46.6 million in 2021, with a notable increase in years lived with disability. It also highlighted growing health inequalities, with a higher burden seen among women, in high SDI countries, and regions like Asia.
The rising incidence of joint disorders is a key driver of the viscosupplementation market. Degenerative conditions are becoming more common due to aging populations and sedentary lifestyles. This is leading to greater demand for non-surgical treatment approaches that provide symptom relief. Viscosupplementation addresses this by improving joint lubrication and mobility. Healthcare systems are recognizing the cost-effectiveness of delaying surgical intervention. In November 2024, an article in Osteoarthritis and Cartilage highlighted that osteoarthritis affected 7.6% of the global population in 2020, with prevalence increasing by 132.2% over the past 30 years. Moreover, it is noted that early-onset OA cases, occurring before age 55, accounted for over half of new diagnoses and 26.1% of total YLDs.
Preference for minimally invasive treatment options is contributing to market expansion. Patients and providers are increasingly opting for procedures that offer reduced recovery time and fewer complications. Viscosupplementation aligns with these needs, supporting its adoption in routine clinical practice. Ongoing developments in formulation are also influencing uptake. Single and multiple-injection regimens are now available to accommodate different patient profiles. In April 2024, a study published in Cureus analyzed arthritis trends among U.S. adults using BRFSS data from 2019 to 2022. The findings underscored rising prevalence and disparities by demographics and health status. These insights support growing adoption of minimally invasive surgeries (MIS) for arthritis, aimed at reducing pain, complications, and recovery time.
Growing awareness among healthcare providers and structured reimbursement policies are further supporting market growth. Continued clinical validation has led to broader acceptance of viscosupplementation in standard care protocols. This is encouraging its use at earlier stages of joint degeneration. Market players are responding with expanded product offerings to meet rising clinical demand. Regional regulatory support has facilitated product availability across key markets. In January 2024, Seikagaku Corporation announced collaborations with Anika Therapeutics and two other manufacturers to enhance multi-injection viscosupplementation products using novel cross-linked hyaluronic acid technologies.
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The growing incidence of osteoarthritis plays a significant role in driving the demand for viscosupplementation. Osteoarthritis, a chronic degenerative joint disease, is the primary cause of enduring disability. It typically emerges after the age of 30 and can progress to a disabling condition within a decade of diagnosis. In March 2025, an article published in Scientific Reports analyzed osteoarthritis data from the Global Burden of Disease Study 2021. The study reported a sharp rise in global OA incidence from 20.9 million cases in 1990 to 46.6 million in 2021, with a notable increase in years lived with disability. It also highlighted growing health inequalities, with a higher burden seen among women, in high SDI countries, and regions like Asia.
The rising incidence of joint disorders is a key driver of the viscosupplementation market. Degenerative conditions are becoming more common due to aging populations and sedentary lifestyles. This is leading to greater demand for non-surgical treatment approaches that provide symptom relief. Viscosupplementation addresses this by improving joint lubrication and mobility. Healthcare systems are recognizing the cost-effectiveness of delaying surgical intervention. In November 2024, an article in Osteoarthritis and Cartilage highlighted that osteoarthritis affected 7.6% of the global population in 2020, with prevalence increasing by 132.2% over the past 30 years. Moreover, it is noted that early-onset OA cases, occurring before age 55, accounted for over half of new diagnoses and 26.1% of total YLDs.
Preference for minimally invasive treatment options is contributing to market expansion. Patients and providers are increasingly opting for procedures that offer reduced recovery time and fewer complications. Viscosupplementation aligns with these needs, supporting its adoption in routine clinical practice. Ongoing developments in formulation are also influencing uptake. Single and multiple-injection regimens are now available to accommodate different patient profiles. In April 2024, a study published in Cureus analyzed arthritis trends among U.S. adults using BRFSS data from 2019 to 2022. The findings underscored rising prevalence and disparities by demographics and health status. These insights support growing adoption of minimally invasive surgeries (MIS) for arthritis, aimed at reducing pain, complications, and recovery time.
Growing awareness among healthcare providers and structured reimbursement policies are further supporting market growth. Continued clinical validation has led to broader acceptance of viscosupplementation in standard care protocols. This is encouraging its use at earlier stages of joint degeneration. Market players are responding with expanded product offerings to meet rising clinical demand. Regional regulatory support has facilitated product availability across key markets. In January 2024, Seikagaku Corporation announced collaborations with Anika Therapeutics and two other manufacturers to enhance multi-injection viscosupplementation products using novel cross-linked hyaluronic acid technologies.
Global Viscosupplementation Market Report Segmentation
This report forecasts revenue growth at the global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, the analyst has segmented the global viscosupplementation market report based on product, end use, and region:Product Outlook (Revenue in USD Billion, 2021 - 2033)
- Single Injection
- Three Injection
- Five Injection
End Use Outlook (Revenue, USD Billion, 2021 - 2033)
- Hospitals
- Orthopedic Clinics/ASCs
Regional Outlook (Revenue, USD Billion, 2021 - 2033)
- North America
- U.S.
- Canada
- Mexico
- Europe
- UK
- France
- Germany
- Italy
- Spain
- Denmark
- Sweden
- Norway
- Asia Pacific
- China
- Japan
- India
- South Korea
- Australia
- Thailand
- Latin America
- Brazil
- Argentina
- Middle East & Africa
- South Africa
- Saudi Arabia
- UAE
- Kuwait
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- Comprehensive Market Analysis: Gain detailed insights into the global market across major regions and segments.
- Competitive Landscape: Explore the market presence of key players worldwide.
- Future Trends: Discover the pivotal trends and drivers shaping the future of the global market.
- Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.
This report addresses:
- Market intelligence to enable effective decision-making
- Market estimates and forecasts from 2018 to 2030
- Growth opportunities and trend analyses
- Segment and regional revenue forecasts for market assessment
- Competition strategy and market share analysis
- Product innovation listing for you to stay ahead of the curve
- COVID-19's impact and how to sustain in these fast-evolving markets
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Table of Contents
Chapter 1. Methodology and Scope
Chapter 2. Executive Summary
Chapter 3. Viscosupplementation Market Variables, Trends & Scope
Chapter 4. Viscosupplementation Market Segment Analysis, By Product, 2021 - 2033 (USD Million)
Chapter 5. Viscosupplementation Market Segment Analysis, By End Use, 2021 - 2033 (USD Million)
Chapter 6. Viscosupplementation Market Segment Analysis, By Region, 2021 - 2033 (USD Million)
Chapter 7. Competitive Landscape
List of Tables
List of Figures
Companies Mentioned
- DePuy Synthes
- Fidia Farmaceutici S.p.A
- Sanofi
- Smith & Nephew PLC
- Anika Therapeutics, Inc.
- Seikagaku Corp.
- Zimmer Biomet
- Ferring Pharmaceuticals B.V.
- Lifecore Biomedical
- LG Life Sciences Ltd.
- F.Hoffmann-La Roche Ltd.
Table Information
Report Attribute | Details |
---|---|
No. of Pages | 118 |
Published | July 2025 |
Forecast Period | 2024 - 2033 |
Estimated Market Value ( USD | $ 5.3 Billion |
Forecasted Market Value ( USD | $ 9.39 Billion |
Compound Annual Growth Rate | 6.2% |
Regions Covered | Global |
No. of Companies Mentioned | 11 |