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Amyotrophic Lateral Sclerosis (Central Nervous System) - Drugs in Development, 2021

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    Drug Pipelines

  • 945 Pages
  • September 2021
  • Region: Global
  • Global Markets Direct
  • ID: 5451348
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The publisher's latest Pharmaceutical and Healthcare disease pipeline guide, 'Amyotrophic Lateral Sclerosis - Drugs In Development, 2021', provides an overview of the Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline landscape. Amyotrophic lateral sclerosis (ALS) is the most common degenerative disease of the motor neuron system. The disorder is named for its underlying pathophysiology, with amyotrophy referring to the atrophy of muscle fibers, which are denervated as their corresponding anterior horn cells degenerate. Lateral sclerosis refers to the changes seen in the lateral columns of the spinal cord as upper motor neuron (UMN) axons in these areas degenerate and are replaced by fibrous astrocytes (gliosis). Symptoms include difficulty breathing, difficulty swallowing, head drop due to weakness of the neck muscles, muscle cramps, speech problems, such as a slow or abnormal speech pattern (slurring of words), voice changes, hoarseness, weight loss.

Report Highlights


This latest pipeline guide provides comprehensive information on the therapeutics under development for Amyotrophic Lateral Sclerosis (Central Nervous System), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and the latest news and press releases. The Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline guide also reviews of key players involved in therapeutic development for Amyotrophic Lateral Sclerosis and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Filing rejected/Withdrawn, Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical, Discovery and Unknown stages are 3, 1, 15, 37, 38, 4, 148, 59 and 2 respectively. Similarly, the Universities portfolio in Phase II, Preclinical and Discovery stages comprises 2, 36 and 12 molecules, respectively.

The Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from the publisher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope


  • The pipeline guide provides a snapshot of the global therapeutic landscape of Amyotrophic Lateral Sclerosis (Central Nervous System).
  • The pipeline guide reviews pipeline therapeutics for Amyotrophic Lateral Sclerosis (Central Nervous System) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Amyotrophic Lateral Sclerosis (Central Nervous System) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Amyotrophic Lateral Sclerosis (Central Nervous System) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Amyotrophic Lateral Sclerosis (Central Nervous System)

Reasons to Buy


  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolios and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Amyotrophic Lateral Sclerosis (Central Nervous System).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Amyotrophic Lateral Sclerosis (Central Nervous System) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

Introduction

Amyotrophic Lateral Sclerosis - Overview

Amyotrophic Lateral Sclerosis - Therapeutics Development

Amyotrophic Lateral Sclerosis - Therapeutics Assessment

Amyotrophic Lateral Sclerosis - Companies Involved in Therapeutics Development

Amyotrophic Lateral Sclerosis - Drug Profiles

Amyotrophic Lateral Sclerosis - Dormant Projects

Amyotrophic Lateral Sclerosis - Discontinued Products

Amyotrophic Lateral Sclerosis - Product Development Milestones

Appendix

List of Tables
  • Number of Products under Development for Amyotrophic Lateral Sclerosis, 2021
  • Number of Products under Development by Companies, 2021
  • Number of Products under Development by Universities/Institutes, 2021
  • Products under Development by Companies, 2021
  • Products under Development by Universities/Institutes, 2021
  • Number of Products by Stage and Target, 2021
  • Number of Products by Stage and Mechanism of Action, 2021
  • Number of Products by Stage and Route of Administration, 2021
  • Number of Products by Stage and Molecule Type, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by 1st Bio Therapeutics Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by 4B Technologies (Suzhou) Co Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Abbisko Therapeutics Co Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Above and Beyond Concierge Therapeutics LLC, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by AC Immune SA, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Aclipse One Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Aclipse Therapeutics LLC, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Actimed Therapeutics Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by AcuraStem Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Adare Pharma Solutions, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Aeterna Zentaris Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by AgoneX Biopharmaceuticals Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by AI Therapeutics Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by AL-S Pharma AG, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Alector Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Alexion Pharmaceuticals Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Allife Medical Science and Technology Co Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by AlphaCognition Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Alsonex Pty Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Amylyx Pharmaceuticals Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Anima Biotech Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Ankar Pharma SL, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Annexon Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Apellis Pharmaceuticals Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Apic Bio Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Apogenix AG, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Applied Genetic Technologies Corp, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Aquilus Pharmaceuticals Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Aquinnah Pharmaceuticals Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by ArmaGen Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by ArunA Biomedical Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Asahi Kasei Pharma Corp, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Asdera LLC, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Ashvattha Therapeutics LLC, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Astellas Pharma Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Astrogen Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Athira Pharma Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Autophagy Neurotherapeutics Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Autotac Bio Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Avanir Pharmaceuticals Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by AZTherapies Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Bach Pharma Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by BenevolentAI Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Biogen Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Biohaven Pharmaceutical Holding Company Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Bioleaders Corp, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Biorchestra Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Bloom Science Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by BrainEver SAS, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by BrainStorm Cell Therapeutics Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Calico Life Sciences LLC, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Capsida Biotherapeutics Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by CavoGene LifeSciences, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by CellCure, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Cellenkos Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by CELLnLIFE Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Cerion LLC, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Chaperone Therapeutics Inc, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Chemigen LLC, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by Chiesi Farmaceutici SpA, 2021
  • Amyotrophic Lateral Sclerosis - Pipeline by CholesteniX Ltd, 2021
  • Amyotrophic Lateral Sclerosis - Dormant Projects, 2021
  • Amyotrophic Lateral Sclerosis - Discontinued Products, 2021

List of Figures
  • Number of Products under Development for Amyotrophic Lateral Sclerosis, 2021
  • Number of Products under Development by Companies, 2021
  • Number of Products under Development by Universities/Institutes, 2021
  • Number of Products by Top 10 Targets, 2021
  • Number of Products by Stage and Top 10 Targets, 2021
  • Number of Products by Top 10 Mechanism of Actions, 2021
  • Number of Products by Stage and Top 10 Mechanism of Actions, 2021
  • Number of Products by Top 10 Routes of Administration, 2021
  • Number of Products by Stage and Top 10 Routes of Administration, 2021
  • Number of Products by Top 10 Molecule Types, 2021
  • Number of Products by Stage and Top 10 Molecule Types, 2021

Companies Mentioned

A selection of companies mentioned in this report includes:

  • 1st Bio Therapeutics Inc
  • 4B Technologies (Suzhou) Co Ltd
  • Abbisko Therapeutics Co Ltd
  • Above and Beyond Concierge Therapeutics LLC
  • AC Immune SA
  • Aclipse One Inc
  • Aclipse Therapeutics LLC
  • Actimed Therapeutics Ltd
  • AcuraStem Inc
  • Adare Pharma Solutions
  • Aeterna Zentaris Inc
  • AgoneX Biopharmaceuticals Inc
  • AI Therapeutics Inc
  • AL-S Pharma AG
  • Alector Inc
  • Alexion Pharmaceuticals Inc
  • Allife Medical Science and Technology Co Ltd
  • AlphaCognition Inc
  • Alsonex Pty Ltd
  • Amylyx Pharmaceuticals Inc
  • Anima Biotech Inc
  • Ankar Pharma SL
  • Annexon Inc
  • Apellis Pharmaceuticals Inc
  • Apic Bio Inc
  • Apogenix AG
  • Applied Genetic Technologies Corp
  • Aquilus Pharmaceuticals Inc
  • Aquinnah Pharmaceuticals Inc
  • ArmaGen Inc
  • ArunA Biomedical Inc
  • Asahi Kasei Pharma Corp
  • Asdera LLC
  • Ashvattha Therapeutics LLC
  • Astellas Pharma Inc
  • Astrogen Ltd
  • Athira Pharma Inc
  • Autophagy Neurotherapeutics Inc
  • Autotac Bio Inc
  • Avanir Pharmaceuticals Inc
  • AZTherapies Inc
  • Bach Pharma Inc
  • BenevolentAI Ltd
  • Biogen Inc
  • Biohaven Pharmaceutical Holding Company Ltd
  • Bioleaders Corp
  • Biorchestra Ltd
  • Bloom Science Inc
  • BrainEver SAS
  • BrainStorm Cell Therapeutics Inc
  • Calico Life Sciences LLC
  • Capsida Biotherapeutics Inc
  • CavoGene LifeSciences
  • CellCure
  • Cellenkos Inc
  • CELLnLIFE Inc
  • Cerion LLC
  • Chaperone Therapeutics Inc
  • Chemigen LLC
  • Chiesi Farmaceutici SpA
  • CholesteniX Ltd
  • Chronos Therapeutics Ltd
  • Clene Inc
  • Clevexel Pharma SA
  • Clinigen Group Plc
  • Coave Therapeutics
  • Cogentis Therapeutics Inc
  • Collaborative Medicinal Development LLC
  • Constant Therapeutics LLC
  • Corcept Therapeutics Inc
  • Corestem Inc
  • Coya Therapeutics Inc
  • CSPC NBP Pharmaceutical Co Ltd
  • Curatis AG
  • CuroNZ Ltd
  • Cytokinetics Inc
  • Daiichi Sankyo Co Ltd
  • Denali Therapeutics Inc
  • Dewpoint Therapeutics Inc
  • Disarm Therapeutics Inc
  • Eikonizo Therapeutics Inc
  • Eisai Co Ltd
  • Eledon Pharmaceuticals Inc
  • Eli Lilly and Co
  • Elixiron Immunotherapeutics Inc
  • Elysium Health Inc
  • EmendoBio Inc
  • Emerald Health Sciences Inc
  • ENCEFA
  • Enveda Biosciences Inc
  • Enzerna Biosciences LLC
  • Eolo Pharma
  • Epigen Biosciences Inc
  • Everfront Biotech Inc
  • Exicure Inc
  • Expansion Therapeutics Inc
  • Expesicor Inc
  • Faze medicines
  • Gene Therapy Research Institution Co Ltd
  • Genentech USA Inc
  • Generoath Co Ltd
  • Genervon Biopharmaceuticals LLC
  • Genetic Intelligence Inc
  • GeNeuro SA
  • Genuv Inc
  • Gilead Sciences Inc
  • Glialogix Inc
  • GlyTag LLC
  • GNT Pharma Co Ltd
  • Grifols SA
  • Grupo Ferrer Internacional S.A.
  • Guangzhou Magpie Pharmaceutical Co Ltd
  • Helixmith Co Ltd
  • Hemostemix Inc
  • Herantis Pharma Plc
  • Hopstem Biotechnology LLC
  • Iltoo Pharma
  • Immunity Pharma Ltd
  • Implicit Bioscience Ltd
  • ImStar Therapeutics Inc
  • InFlectis BioScience SAS
  • Inmune Bio Inc
  • InnoMedica Holding AG
  • InnoPharmaScreen Inc
  • Io Therapeutics Inc
  • Ionis Pharmaceuticals Inc
  • Iron Horse Therapeutics Inc
  • Jiangsu Ouwei Pharmaceutical Co Ltd
  • Junaxo Inc
  • K Pharma Inc
  • K-Pax Pharmaceuticals Inc
  • Kadimastem Ltd
  • Keapstone Therapeutics Ltd
  • Klogene Therapeutics Inc
  • Knopp Biosciences LLC
  • Kringle Pharma Inc
  • Kyorin Pharmaceutical Co Ltd
  • Lascco SA
  • Lauren Sciences LLC
  • LifeSplice Pharma LLC
  • Locanabio Inc
  • Longboard Pharmaceuticals Inc
  • Maas Biolab
  • Maze Therapeutics Inc
  • MedDay SA
  • MeiraGTx Holdings Plc
  • Merck & Co Inc
  • Meta-IQ ApS
  • MetVital Inc
  • MimeTech Srl
  • Mitochon Pharmaceuticals Inc
  • Mitochondria In Motion Inc
  • Mitoconix Bio Ltd
  • MitoDys Therapeutics Ltd
  • Mitsubishi Tanabe Pharma Corp
  • NeuExcell Therapeutics Inc
  • Neugen Pharma Inc
  • Neuracle Science Co Ltd
  • Neurimmune Holding AG
  • Neurodegeneration Therapeutics Inc
  • NeuroGenesis Ltd
  • Neuropath Therapeutics Ltd
  • Neuroplast BV
  • Neuropore Therapies Inc
  • NeuroSense Therapeutics Ltd
  • Neurotune AG
  • Nevrox Ltd
  • New Biotic Inc
  • Newron Pharmaceuticals SpA
  • Novartis AG
  • Novartis Gene Therapies
  • NuNerve Pty Ltd
  • OptiKira LLC
  • Orchard Therapeutics Plc
  • Orpheris Inc
  • Oxford BioMedica Plc
  • Palisade Bio, Inc
  • Parnia Stem Cell Knowledge-Based Co
  • Passage Bio Inc
  • Pfizer Inc
  • PharmaTher Holdings Ltd
  • PharmAust Ltd
  • PharmEnable Ltd
  • Pharnext SA
  • Plex Pharmaceuticals Inc
  • Priavoid GmbH
  • Prilenia Therapeutics Development Ltd
  • ProMIS Neurosciences Inc
  • Prosetta Biosciences Inc
  • Prothena Corp Plc
  • Prous Institute for Biomedical Research SA
  • PTC Therapeutics Inc
  • Q Therapeutics Inc
  • Quell Therapeutics Ltd
  • QurAlis Corporation
  • Ra Pharmaceuticals Inc
  • Rapa Therapeutics LLC
  • RASRx LLC
  • reMYND NV
  • ReoStem LLC
  • ResQ Biotech
  • Retrotope Inc
  • Revalesio Corp
  • Samus Therapeutics Inc
  • Sangamo Therapeutics Inc
  • Seelos Therapeutics, Inc.
  • Shinkei Therapeutics LLC
  • Sio Gene Therapies Inc
  • SOLA Biosciences LLC
  • Spedding Research Solutions SAS
  • Spinogenix Inc
  • Stealth BioTherapeutics Corp
  • Suzhou Auzone Biological Technology Co Ltd
  • Takara Bio Inc
  • Talon Pharmaceutical Services Inc
  • Tasly Biopharmaceuticals Co Ltd
  • Tempero Bio
  • Teva Pharmaceutical Industries Ltd
  • Thera Neuropharma Inc
  • Theragen Etex Co Ltd
  • Theratome Bio Inc
  • TikoMed AB
  • Tolerion Inc
  • Tranquis Therapeutics Inc
  • Transposon Therapeutics Inc
  • Treeway BV
  • Treventis Corp
  • Triplet Therapeutics Inc
  • Ultragenyx Pharmaceutical Inc
  • UniQure NV
  • Unity Biotechnology Inc
  • Vaxxinity Inc
  • VectorY Therapeutics Inc
  • Velvio GmbH
  • Vera Therapeutics Inc
  • Verge Genomics Inc
  • Viridian Therapeutics Inc
  • Voyager Therapeutics Inc
  • Wave Life Sciences Ltd
  • Xalud Therapeutics Inc
  • Xcelthera INC
  • Xonovo Inc
  • Yantai YenePharma Co Ltd
  • Yooyoung Pharm Co Ltd
  • Yumanity Therapeutics Inc
  • Zhittya Genesis Medicine Inc
  • ZZ Biotech LLC