Bioinformatics allows researchers to answer biological questions with advanced computational methods which involves the application of statistics and mathematical modeling. Structural bioinformatics enables the prediction and analysis of 3D structures of macromolecules while Computer Aided Drug Designing (CADD) assists scientists to design effective active molecules against diseases. However, the concepts in structural bioinformatics and CADD can be complex to understand for students and educated laymen.
This quick guideline is intended as a basic manual for beginner students and instructors involved in bioinformatics and computational chemistry courses. Readers will learn the basics of structural bioinformatics, primary and secondary analysis and prediction, structural visualization, structural analysis and molecular docking. Therefore, the book is a useful handbook for aspiring scholars who wish to learn the basic concepts in computational analysis of biomolecules.
This quick guideline is intended as a basic manual for beginner students and instructors involved in bioinformatics and computational chemistry courses. Readers will learn the basics of structural bioinformatics, primary and secondary analysis and prediction, structural visualization, structural analysis and molecular docking. Therefore, the book is a useful handbook for aspiring scholars who wish to learn the basic concepts in computational analysis of biomolecules.
Table of Contents
Chapter 1 Introduction to Structural Bioinformatics
Chapter 2 Protein Primary Sequence Analysis
Chapter 3 Secondary Structure Analyses
Chapter 4 3D Structure Prediction
Chapter 5 Protein 3D Structure Assessment, Evaluation, and Validation
Chapter 6 Ligand-Based Computational Molecular Docking Analysis
Chapter 7 Protein-Ligand Interactions
Subject Index
Author
- Sheikh Arslan Sehgal
- Rana Adnan Tahir
- Muhammad Waqas
