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22q11.2 Deletion Syndrome - Market Insight, Epidemiology and Market Forecast -2032

  • ID: 5457234
  • Report
  • January 2022
  • Region: Global
  • 200 Pages
  • DelveInsight

FEATURED COMPANIES

  • Enzyvant
  • Roivant Sciences
  • Sumitomo Dainippon Pharma
  • Zynerba Pharmaceuticals
This "22q11.2 Deletion Syndrome- Market Insights, Epidemiology, and Market Forecast-2032" report delivers an in-depth understanding of the 22q11.2 Deletion Syndrome, historical and forecasted epidemiology as well as the 22q11.2 Deletion Syndrome market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

The 22q11.2 Deletion Syndrome market report provides current treatment practices, emerging drugs, 22q11.2 Deletion Syndrome market share of the individual therapies, current and forecasted 22q11.2 Deletion Syndrome market Size from 2019 to 2032 segmented by seven major markets. The Report also covers current 22q11.2 Deletion Syndrome treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assesses the underlying potential of the market.

Geography Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan

Study Period: 2019-2032

22q11.2 Deletion Syndrome Disease Understanding and Treatment Algorithm


The 22q11.2 Deletion Syndrome market report gives a thorough understanding of the 22q11.2 Deletion Syndrome by including details such as disease definition, symptoms, causes, pathophysiology, diagnosis and treatment.

Diagnosis


This segment of the report covers the detailed diagnostic methods or tests for 22q11.2 Deletion Syndrome.

Treatment


It covers the details of conventional and current medical therapies available in the 22q11.2 Deletion Syndrome market for the treatment of the condition. It also provides 22q11.2 Deletion Syndrome treatment algorithms and guidelines in the United States, Europe, and Japan.

22q11.2 Deletion Syndrome Epidemiology


The 22q11.2 Deletion Syndrome epidemiology division provide insights about historical and current 22q11.2 Deletion Syndrome patient pool and forecasted trend for every seven major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of The report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

Key Findings


The disease epidemiology covered in the report provides historical as well as forecasted 22q11.2 Deletion Syndrome epidemiology scenario in the 7MM covering the United States, EU5 countries (Germany, Spain, Italy, France, and the United Kingdom), and Japan from 2019 to 2032.

Country Wise- 22q11.2 Deletion Syndrome Epidemiology


The epidemiology segment also provides the 22q11.2 Deletion Syndrome epidemiology data and findings across the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

22q11.2 Deletion Syndrome Drug Chapters


Drug chapter segment of the 22q11.2 Deletion Syndrome report encloses the detailed analysis of 22q11.2 Deletion Syndrome marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the 22q11.2 Deletion Syndrome clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.

Marketed Drugs


The report provides the details of the marketed product available for 22q11.2 Deletion Syndrome treatment.

22q11.2 Deletion Syndrome Emerging Drugs


The report provides the details of the emerging therapies under the late and mid-stage of development for 22q11.2 Deletion Syndrome treatment.

22q11.2 Deletion Syndrome Market Outlook


The 22q11.2 Deletion Syndrome market outlook of the report helps to build the detailed comprehension of the historic, current, and forecasted 22q11.2 Deletion Syndrome market trends by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.

This segment gives a thorough detail of 22q11.2 Deletion Syndrome market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria's, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

According to the publisher, 22q11.2 Deletion Syndrome market in 7MM is expected to change in the study period 2019-2032.

Key Findings


This section includes a glimpse of the 22q11.2 Deletion Syndrome market in 7MM.

The United States Market Outlook


This section provides the total 22q11.2 Deletion Syndrome market size and market size by therapies in the United States.

EU-5 Countries: Market Outlook


The total 22q11.2 Deletion Syndrome market size and market size by therapies in Germany, France, Italy, Spain, and the United Kingdom is provided in this section.

Japan Market Outlook


The total 22q11.2 Deletion Syndrome market size and market size by therapies in Japan is also mentioned.

22q11.2 Deletion Syndrome Drugs Uptake


This section focusses on the rate of uptake of the potential drugs recently launched in the 22q11.2 Deletion Syndrome market or expected to get launched in the market during the study period 2019-2032. The analysis covers 22q11.2 Deletion Syndrome market uptake by drugs; patient uptake by therapies; and sales of each drug.

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

22q11.2 Deletion Syndrome Pipeline Development Activities


The report provides insights into different therapeutic candidates in Phase II, and Phase III stage. It also analyses 22q11.2 Deletion Syndrome key players involved in developing targeted therapeutics.

Pipeline Development Activities


The report covers the detailed information of collaborations, acquisition and merger, licensing, patent details and other information for 22q11.2 Deletion Syndrome emerging therapies.

Reimbursement Scenario in 22q11.2 Deletion Syndrome


Approaching reimbursement proactively can have a positive impact both during the late stages of product development and well after product launch. In a report, we take reimbursement into consideration to identify economically attractive indications and market opportunities. When working with finite resources, the ability to select the markets with the fewest reimbursement barriers can be a critical business and price strategy.

KOL-Views


To keep up with current market trends, we take KOLs and SME's opinion working in 22q11.2 Deletion Syndrome domain through primary research to fill the data gaps and validate our secondary research. Their opinion helps to understand and validate current and emerging therapies treatment patterns or 22q11.2 Deletion Syndrome market trend. This will support the clients in potential upcoming novel treatment by identifying the overall scenario of the market and the unmet needs.

Competitive Intelligence Analysis


The publisher performs Competitive and Market Intelligence analysis of the 22q11.2 Deletion Syndrome Market by using various Competitive Intelligence tools that include - SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies etc. The inclusion of the analysis entirely depends upon the data availability.

Scope of the Report

  • The report covers the descriptive overview of 22q11.2 Deletion Syndrome, explaining its causes, signs and symptoms, pathophysiology, diagnosis and currently available therapies
  • Comprehensive insight has been provided into the 22q11.2 Deletion Syndrome epidemiology and treatment in the 7MM
  • Additionally, an all-inclusive account of both the current and emerging therapies for 22q11.2 Deletion Syndrome are provided, along with the assessment of new therapies, which will have an impact on the current treatment landscape
  • A detailed review of 22q11.2 Deletion Syndrome market; historical and forecasted is included in the report, covering drug outreach in the 7MM
  • The report provides an edge while developing business strategies, by understanding trends shaping and driving the global 22q11.2 Deletion Syndrome market

Report Highlights

  • In the coming years, 22q11.2 Deletion Syndrome market is set to change due to the rising awareness of the disease, and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market
  • The companies and academics are working to assess challenges and seek opportunities that could influence 22q11.2 Deletion Syndrome R&D. The therapies under development are focused on novel approaches to treat/improve the disease condition
  • Major players are involved in developing therapies for 22q11.2 Deletion Syndrome. Launch of emerging therapies will significantly impact the 22q11.2 Deletion Syndrome market
  • A better understanding of disease pathogenesis will also contribute to the development of novel therapeutics for 22q11.2 Deletion Syndrome
  • Our in-depth analysis of the pipeline assets across different stages of development (Phase III and Phase II), different emerging trends and comparative analysis of pipeline products with detailed clinical profiles, key cross-competition, launch date along with product development activities will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the research and development activities

22q11.2 Deletion Syndrome Report Insights

  • Patient Population
  • Therapeutic Approaches
  • 22q11.2 Deletion Syndrome Pipeline Analysis
  • 22q11.2 Deletion Syndrome Market Size and Trends
  • Market Opportunities
  • Impact of upcoming Therapies

22q11.2 Deletion Syndrome Report Key Strengths

  • 11 Years Forecast
  • 7MM Coverage
  • 22q11.2 Deletion Syndrome Epidemiology Segmentation
  • Key Cross Competition
  • Highly Analyzed Market
  • Drugs Uptake

22q11.2 Deletion Syndrome Report Assessment


Current Treatment Practices
  • Unmet Needs
  • Pipeline Product Profiles
  • Market Attractiveness
  • Market Drivers and Barriers

Key Questions Answered


Market Insights:

  • What was the 22q11.2 Deletion Syndrome market share (%) distribution in 2019 and how it would look like in 2032?
  • What would be the 22q11.2 Deletion Syndrome total market size as well as market size by therapies across the 7MM during the forecast period (2019-2032)?
  • What are the key findings pertaining to the market across 7MM and which country will have the largest 22q11.2 Deletion Syndrome market size during the forecast period (2019-2032)?
  • At what CAGR, the 22q11.2 Deletion Syndrome market is expected to grow in 7MM during the forecast period (2019-2032)?
  • What would be the 22q11.2 Deletion Syndrome market outlook across the 7MM during the forecast period (2019-2032)?
  • What would be the 22q11.2 Deletion Syndrome market growth till 2032, and what will be the resultant market Size in the year 2032?
  • How would the market drivers, barriers and future opportunities affect the market dynamics and subsequent analysis of the associated trends?

Epidemiology Insights:

  • What is the disease risk, burden and unmet needs of the 22q11.2 Deletion Syndrome?
  • What is the historical 22q11.2 Deletion Syndrome patient pool in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
  • What would be the forecasted patient pool of 22q11.2 Deletion Syndrome in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan?
  • What will be the growth opportunities in the 7MM with respect to the patient population pertaining to 22q11.2 Deletion Syndrome?
  • Out of all 7MM countries, which country would have the highest prevalent population of 22q11.2 Deletion Syndrome during the forecast period (2019-2032)?
  • At what CAGR the population is expected to grow in 7MM during the forecast period (2019-2032)?

Current Treatment Scenario, Marketed Drugs and Emerging Therapies:

  • What are the current options for the 22q11.2 Deletion Syndrome treatment, along with the approved therapy?
  • What are the current treatment guidelines for the treatment of 22q11.2 Deletion Syndrome in the USA, Europe, and Japan?
  • What are the 22q11.2 Deletion Syndrome marketed drugs and their MOA, regulatory milestones, product development activities, advantages, disadvantages, safety and efficacy, etc.?
  • How many companies are developing therapies for the treatment of 22q11.2 Deletion Syndrome?
  • How many therapies are developed by each company for 22q11.2 Deletion Syndrome treatment?
  • How many are emerging therapies in mid-stage, and late stage of development for 22q11.2 Deletion Syndrome treatment?
  • What are the key collaborations (Industry - Industry, Industry - Academia), Mergers and acquisitions, licensing activities related to the 22q11.2 Deletion Syndrome therapies?
  • What are the recent novel therapies, targets, mechanisms of action and technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for 22q11.2 Deletion Syndrome and their status?
  • What are the key designations that have been granted for the emerging therapies for 22q11.2 Deletion Syndrome?
  • What are the global historical and forecasted market of 22q11.2 Deletion Syndrome?

Reasons to Buy

  • The report will help in developing business strategies by understanding trends shaping and driving the 22q11.2 Deletion Syndrome market
  • To understand the future market competition in the 22q11.2 Deletion Syndrome market and Insightful review of the key market drivers and barriers
  • Organize sales and marketing efforts by identifying the best opportunities for 22q11.2 Deletion Syndrome in the US, Europe (Germany, Spain, Italy, France, and the United Kingdom) and Japan
  • Identification of strong upcoming players in the market will help in devising strategies that will help in getting ahead of competitors
  • Organize sales and marketing efforts by identifying the best opportunities for 22q11.2 Deletion Syndrome market
  • To understand the future market competition in the 22q11.2 Deletion Syndrome market
Note: Product cover images may vary from those shown

FEATURED COMPANIES

  • Enzyvant
  • Roivant Sciences
  • Sumitomo Dainippon Pharma
  • Zynerba Pharmaceuticals

1. Key Insights2. Executive Summary of 22q11.2 Deletion Syndrome3. Competitive Intelligence Analysis for 22q11.2 Deletion Syndrome
4. 22q11.2 Deletion Syndrome: Market Overview at a Glance
4.1. 22q11.2 Deletion Syndrome Total Market Share (%) Distribution in 2019
4.2. 22q11.2 Deletion Syndrome Total Market Share (%) Distribution in 2032
5. 22q11.2 Deletion Syndrome: Disease Background and Overview
5.1. Introduction
5.2. Sign and Symptoms
5.3. Pathophysiology
5.4. Risk Factors
5.5. Diagnosis
6. Patient Journey
7. 22q11.2 Deletion Syndrome Epidemiology and Patient Population
7.1. Epidemiology Key Findings
7.2. Assumptions and Rationale: 7MM
7.3. Epidemiology Scenario: 7MM
7.3.1. 22q11.2 Deletion Syndrome Epidemiology Scenario in the 7MM (2019-2032)
7.4. United States Epidemiology
7.4.1. 22q11.2 Deletion Syndrome Epidemiology Scenario in the United States (2019-2032)
7.5. EU-5 Country-wise Epidemiology
7.5.1. Germany Epidemiology
7.5.1.1. 22q11.2 Deletion Syndrome Epidemiology Scenario in Germany (2019-2032)
7.5.2. France Epidemiology
7.5.2.1. 22q11.2 Deletion Syndrome Epidemiology Scenario in France (2019-2032)
7.5.3. Italy Epidemiology
7.5.3.1. 22q11.2 Deletion Syndrome Epidemiology Scenario in Italy (2019-2032)
7.5.4. Spain Epidemiology
7.5.4.1. 22q11.2 Deletion Syndrome Epidemiology Scenario in Spain (2019-2032)
7.5.5. United Kingdom Epidemiology
7.5.5.1. 22q11.2 Deletion Syndrome Epidemiology Scenario in the United Kingdom (2019-2032)
7.5.6. Japan Epidemiology
7.5.6.1. 22q11.2 Deletion Syndrome Epidemiology Scenario in Japan (2019-2032)
8. Treatment Algorithm, Current Treatment, and Medical Practices
8.1. 22q11.2 Deletion Syndrome Treatment and Management
8.2. 22q11.2 Deletion Syndrome Treatment Algorithm
9. Unmet Needs10. Key Endpoints of 22q11.2 Deletion Syndrome Treatment
11. Marketed Products
11.1. List of Marketed Products in the 7MM
11.2. Drug Name: Company Name
11.2.1. Product Description
11.2.2. Regulatory Milestones
11.2.3. Other Developmental Activities
11.2.4. Pivotal Clinical Trials
11.2.5. Summary of Pivotal Clinical Trial
List to be continued in report
12. Emerging Therapies
12.1. Key Cross
12.2. Drug Name: Company Name
12.2.1. Product Description
12.2.2. Other Developmental Activities
12.2.3. Clinical Development
12.2.4. Safety and Efficacy
12.2.5. Product Profile
List to be continued in report
13. 22q11.2 Deletion Syndrome: Seven Major Market Analysis
13.1. Key Findings
13.2. 22q11.2 Deletion Syndrome Market Size in 7MM
13.3. 22q11.2 Deletion Syndrome Market Size by Therapies in the 7MM
14. Attribute analysis
15. 7MM: Market Outlook
15.1. United States: Market Size
15.1.1. 22q11.2 Deletion Syndrome Total Market Size in the United States
15.1.2. 22q11.2 Deletion Syndrome Market Size by Therapies in the United States
15.2. EU-5 countries: Market Size and Outlook
15.3. Germany Market Size
15.3.1. 22q11.2 Deletion Syndrome Total Market Size in Germany
15.3.2. 22q11.2 Deletion Syndrome Market Size by Therapies in Germany
15.4. France Market Size
15.4.1. 22q11.2 Deletion Syndrome Total Market Size in France
15.4.2. 22q11.2 Deletion Syndrome Market Size by Therapies in France
15.5. Italy Market Size
15.5.1. 22q11.2 Deletion Syndrome Total Market Size in Italy
15.5.2. 22q11.2 Deletion Syndrome Market Size by Therapies in Italy
15.6. Spain Market Size
15.6.1. 22q11.2 Deletion Syndrome Total Market Size in Spain
15.6.2. 22q11.2 Deletion Syndrome Market Size by Therapies in Spain
15.7. United Kingdom Market Size
15.7.1. 22q11.2 Deletion Syndrome Total Market Size in the United Kingdom
15.7.2. 22q11.2 Deletion Syndrome Market Size by Therapies in the United Kingdom
15.8. Japan Market Outlook
15.8.1. Japan Market Size
15.8.2. 22q11.2 Deletion Syndrome Total Market Size in Japan
15.8.3. 22q11.2 Deletion Syndrome Market Size by Therapies in Japan
16. Access and Reimbursement Overview of 22q11.2 Deletion Syndrome17. KOL Views18. Market Drivers19. Market Barriers
20. Appendix
20.1. Bibliography
20.2. Report Methodology
21. Publisher Capabilities22. Disclaimer
23. About the Publisher
*The table of contents is not exhaustive; the final content may vary.
List of Tables
Table 1: 7MM 22q11.2 Deletion Syndrome Epidemiology (2019-2032)
Table 2: 7MM 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases (2019-2032)
Table 3: 22q11.2 Deletion Syndrome Epidemiology in the United States (2019-2032)
Table 4: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in the United States (2019-2032)
Table 5: 22q11.2 Deletion Syndrome Epidemiology in Germany (2019-2032)
Table 6: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in Germany (2019-2032)
Table 7: 22q11.2 Deletion Syndrome Epidemiology in France (2019-2032)
Table 8: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in France (2019-2032)
Table 9: 22q11.2 Deletion Syndrome Epidemiology in Italy (2019-2032)
Table 10: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in Italy (2019-2032)
Table 11: 22q11.2 Deletion Syndrome Epidemiology in Spain (2019-2032)
Table 12: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in Spain (2019-2032)
Table 13: 22q11.2 Deletion Syndrome Epidemiology in the UK (2019-2032)
Table 14: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in the UK (2019-2032)
Table 15: 22q11.2 Deletion Syndrome Epidemiology in Japan (2019-2032)
Table 16: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in Japan (2019-2032)
Table 17: Drug Name, Clinical Trials by Recruitment status
Table 18: Drug Name, Clinical Trials by Zone
Table 19: Total Seven Major Market Size in USD, Million (2019-2032)
Table 20: Region-wise Market Size in USD, Million (2019-2032)
Table 21: 7MM-Market Size by Therapy in USD, Million (2019-2032)
Table 22: United States Market Size in USD, Million (2019-2032)
Table 23: United States Market Size by Therapy in USD, Million (2019-2032)
Table 24: Germany Market Size in USD, Million (2019-2032)
Table 25: Germany Market Size by Therapy in USD, Million (2019-2032)
Table 26: France Market Size in USD, Million (2019-2032)
Table 27: France Market Size by Therapy in USD, Million (2019-2032)
Table 28: Italy Market Size in USD, Million (2019-2032)
Table 29: Italy Market Size by Therapy in USD, Million (2019-2032)
Table 30: Spain Market Size in USD, Million (2019-2032)
Table 31: Spain Market Size by Therapy in USD, Million (2019-2032)
Table 32: United Kingdom Market Size in USD, Million (2019-2032)
Table 33: United Kingdom Market Size by Therapy in USD, Million (2019-2032)
Table 34: Japan Market Size in USD, Million (2019-2032)
Table 35: Japan Market Size by Therapy in USD, Million (2019-2032)
*The list of tables is not exhaustive; the final content may vary
List of Figures
Figure 1: 7MM 22q11.2 Deletion Syndrome Epidemiology (2019-2032)
Figure 2: 7MM 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases (2019-2032)
Figure 3: 22q11.2 Deletion Syndrome Epidemiology in the United States (2019-2032)
Figure 4: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in the United States (2019-2032)
Figure 5: 22q11.2 Deletion Syndrome Epidemiology in Germany (2019-2032)
Figure 6: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in Germany (2019-2032)
Figure 7: 22q11.2 Deletion Syndrome Epidemiology in France (2019-2032)
Figure 8: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in France (2019-2032)
Figure 9: 22q11.2 Deletion Syndrome Epidemiology in Italy (2019-2032)
Figure 10: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in Italy (2019-2032)
Figure 11: 22q11.2 Deletion Syndrome Epidemiology in Spain (2019-2032)
Figure 12: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in Spain (2019-2032)
Figure 13: 22q11.2 Deletion Syndrome Epidemiology in the UK (2019-2032)
Figure 14: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in the UK (2019-2032)
Figure 15: 22q11.2 Deletion Syndrome Epidemiology in Japan (2019-2032)
Figure 16: 22q11.2 Deletion Syndrome Diagnosed and Treatable Cases in Japan (2019-2032)
Figure 17: Drug Name, Clinical Trials by Recruitment status
Figure 18: Drug Name, Clinical Trials by Zone
Figure 19: Total Seven Major Market Size in USD, Million (2019-2032)
Figure 20: Region-wise Market Size in USD, Million (2019-2032)
Figure 21: 7MM-Market Size by Therapy in USD, Million (2019-2032)
Figure 22: United States Market Size in USD, Million (2019-2032)
Figure 23: United States Market Size by Therapy in USD, Million (2019-2032)
Figure 24: Germany Market Size in USD, Million (2019-2032)
Figure 25: Germany Market Size by Therapy in USD, Million (2019-2032)
Figure 26: France Market Size in USD, Million (2019-2032)
Figure 27: France Market Size by Therapy in USD, Million (2019-2032)
Figure 28: Italy Market Size in USD, Million (2019-2032)
Figure 29: Italy Market Size by Therapy in USD, Million (2019-2032)
Figure 30: Spain Market Size in USD, Million (2019-2032)
Figure 31: Spain Market Size by Therapy in USD, Million (2019-2032)
Figure 32: United Kingdom Market Size in USD, Million (2019-2032)
Figure 33: United Kingdom Market Size by Therapy in USD, Million (2019-2032)
Figure 34: Japan Market Size in USD, Million (2019-2032)
Figure 35: Japan Market Size by Therapy in USD, Million (2019-2032)
*The list of figures is not exhaustive; the final content may vary
Note: Product cover images may vary from those shown

A selection of companies mentioned in this report includes:

  • Zynerba Pharmaceuticals
  • Enzyvant
  • Roivant Sciences
  • Sumitomo Dainippon Pharma
Note: Product cover images may vary from those shown