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Highlights
Black Diamond Therapeutics Inc (Black Diamond) is a clinical-stage pharmaceutical company focused on developing therapies for oncogenic mutations in cancer patients. The company's main activities involve the establishment of MasterKey therapies designed to target families of oncogenic mutations, aiming to address genetically defined patient populations and overcome treatment resistance. Black Diamond's major clinical-stage programs include Silevertinib, a brain-penetrant, fourth-generation epidermal growth factor receptor (EGFR) MasterKey inhibitor, and BDTX-4933, a brain-penetrant, RAF MasterKey inhibitor targeting KRAS, NRAS, and BRAF alterations in solid tumors. It is also focusing on the development of BDTX-4876 for the treatment of achondroplasia or solid tumors. The company has its operations in Massachusetts and New York, the US. Black Diamond is headquartered in Cambridge, Massachusetts, the USBlack Diamond Therapeutics Inc Key Recent Developments
- May 22, 2026: Black Diamond Therapeutics to Participate in Jefferies Global Healthcare Conference
- May 19, 2026: Black Diamond Therapeutics to Host Webcast Highlighting Updated Phase 2 Results of Silevertinib in First-Line EGFRm NSCLC
- Nov 06, 2025: Black Diamond Therapeutics Reports Third Quarter 2025 Financial Results and Provides Corporate Update
- Aug 07, 2025: Black Diamond Therapeutics Announces Q2 2025 Results and Reports Corporate Update
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Table of Contents
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- Wayshine Biopharma Inc
- Voronoi, Inc.
- Verastem Inc
- Taiho Oncology Inc
- Summit Therapeutics Inc
- Shanghai Allist Pharmaceuticals Co Ltd
- Relay Therapeutics Inc
- Puma Biotechnology Inc
- Mirati Therapeutics Inc
- Merck & Co Inc
- Kinnate Biopharma Inc
- J Ints Bio Co Ltd
- Incyte Corp
- Deciphera Pharmaceuticals Inc
- Boehringer Ingelheim International GmbH
- Blueprint Medicines Corp
- Bayer AG
- AstraZeneca Plc
- Arrivent Biopharma Inc
- Akeso Inc

