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Helicobacter Pylori Infections - Epidemiology Forecast - 2034

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    Report

  • 90 Pages
  • March 2024
  • Region: Global
  • DelveInsight
  • ID: 5525121
This ‘Helicobacter pylori Infection - Epidemiology Forecast - 2034’ report delivers an in-depth understanding of Helicobacter pylori Infection, historical and forecasted epidemiology, as well as the trends in the United States, EU4 (Germany, France, Italy, and Spain), and the United Kingdom, and Japan.

H. pylori Infection Understanding

H. pylori is a spiral-shaped, flagellated Gram-negative bacterium colonizing the human stomach lining. Although major infected persons remain asymptomatic, H. pylori infection has been directly linked to several conditions - particularly chronic gastritis, which can evolve either into peptic ulcer diseases or the development of preneoplastic lesions (intestinal metaplasia, dysplasia) and adenocarcinoma. Moreover, H. pylori infection is designated as a Class I carcinogen by the World Health Organization (WHO) and is a qualifying pathogen under the US FDA GAIN Act.

The symptoms associated with H. pylori infections are synonymous with other gastric conditions. Patients harboring the bacteria show symptoms, such as abdominal pain, nausea, vomiting, and the development of dyspepsia only after gastritis and peptic ulcer disease are initiated.

The infection is usually transmitted by the fecal-oral, gastric-oral, oral-oral, or sexual routes, and its prevalence varies widely with geography. Generally, the prevalence is higher in developing and resource-poor countries than in developed countries and is usually impacted by climatic conditions, host-microbe interaction, genetics, GI microbiota, or medication.

H. pylori Infection Diagnosis

There is no single accurate diagnostic tool or method, and the current diagnosis regime is usually a combination of invasive and noninvasive methods.

The noninvasive methods that determine eradication rates are based on the presence of bacterial enzymes, antigens, antibodies, or DNA sequences and include 13C or 14C UBT, SAT, serology, etc. In contrast, the invasive methods include endoscopy and gastric biopsy followed by RUT, histology, culture, or a clinically significant PCR.

H. pylori Infection Epidemiology Perspective by the publisher

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by total diagnosed prevalent cases of H. pylori infection, gender-specific diagnosed prevalent cases of H. pylori infection, and age-specific diagnosed prevalent cases of H. pylori infection in the 7MM covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan from 2020 to 2034.

H. pylori infection Detailed Epidemiology Segmentation

  • According to these estimates, in 2022, the total diagnosed prevalent cases of H. pylori infection in the 7MM were approximately 321,217,226 cases; these cases are expected to increase during the study period (2020-2034).
  • In 2022, the US accounted for the highest cases of diagnosed prevalent cases of H. pylori infection among the 7MM, with nearly 118,650,370 cases, expected to increase by 2034.
  • Among EU4 and the UK, France had the highest diagnosed population of H. pylori infection, with approximately 31,935,563 cases, followed by Germany and Italy in 2022. On the other hand, the UK had the lowest number of diagnosed H. pylori infection cases in 2022.
  • The gender-specific diagnosed prevalent cases of H. pylori infection in the US were nearly 56,547,145 for females and 62,103,226 for males in 2022 which are expected to increase within the forecast period.
  • Among EU4 and the UK, a higher percentage of age-specific diagnosed prevalent cases was observed in an age group above 40 years and accounted for approximately 77,628,236 cases, followed by nearly 47,855,294 cases for 20-40 years and 12,913,978 cases for the 0-20 years in 2022.
  • In 2022, Japan accounted for approximately 64,169,348 diagnosed prevalent cases of H.pylori infection out of which nearly 37,429,981 age-specific diagnosed prevalent H. pylori infection cases in the age group above 40 years, nearly 19,250,804 cases in the 20-40 years age group, and approximately 7,488,563 cases for the 0-20 years age group.

Scope of the Report

  • The report covers a descriptive overview of H. pylori infection, explaining its symptoms, pathophysiology, and various diagnostic approaches.
  • The report provides insight into the 7MM historical and forecasted patient pool covering the United States, EU4 (Germany, France, Italy, and Spain) the United Kingdom, and Japan.
  • The report assesses the disease risk and burden of H. pylori infection.
  • The report helps recognize the growth opportunities in the 7MM concerning the patient population.
  • The report provides the segmentation of the disease epidemiology for the 7MM, by total diagnosed prevalent cases of H. pylori infection, gender-specific diagnosed prevalent cases of H. pylori infection, and age-specific diagnosed prevalent cases of H. pylori infection.

Report Highlights

  • 12 years forecast of H. pylori infection
  • The 7MM Coverage
  • Total diagnosed prevalent cases of H. pylori infection
  • Gender-specific diagnosed prevalent cases of H. pylori infection
  • Age-specific diagnosed prevalent cases of H. pylori infection

Key Questions Answered

  • What are the disease risks and burdens of H. pylori infection?
  • What is the historical H. pylori infection patient pool in the United States, EU4 (Germany, France, Italy, and Spain) the United Kingdom, and Japan?
  • What would be the forecasted patient pool of H. pylori infection at the 7MM level?
  • What growth opportunities will be across the 7MM concerning the patient population with H. pylori infection?
  • Which country would have the highest diagnosed prevalent population of H. pylori infection among the countries mentioned above during the forecast period (2023-2034)?
  • At what CAGR is the population expected to grow across the 7MM forecast period (2023-2034)?

Reasons to Buy

The H. pylori infection report will allow the user to:

  • Develop business strategies by understanding the trends shaping and driving the 7MM H. pylori infection epidemiology forecast.
  • The H. pylori infection epidemiology report and model were written and developed by Masters and PhD level epidemiologists.
  • The H. pylori infection epidemiology model developed by the publisher is easy to navigate, interactive with a dashboard, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports the data presented in the report and showcases disease trends over the 12-year forecast period using reputable sources.

Key Assessments

  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of Disease by Segmentation
  • Factors Driving Growth in a Specific Patient Population

Geographies Covered

  • The United States
  • EU4 (Germany, France, Italy, and Spain) and the United Kingdom
  • Japan

Study Period: 2020-2034

Table of Contents

1. Key Insights2. Report Introduction
3. H. pylori infection Epidemiology Overview at a Glance
3.1. Patient Share (%) Distribution of H. pylori Infection in 2020
3.2. Patient Share (%) Distribution of H. pylori Infection in 2034
4. Methodology of H. pylori Infection Epidemiology5. Executive Summary of H. pylori Infection
6. Disease Background and Overview
6.1. Introduction of H. pylori Infection
6.2. Symptoms Associated with H. pylori Infection
6.3. Causes
6.4. Risk Factors
6.4.1. Socioeconomic Status and Environmental Conditions
6.4.2. Lifestyle Habits
6.4.3. Occupational Hazards
6.5. Route of Transmission
6.6. Pathophysiology of H. pylori Infection
6.6.1. Immunopathogenesis of H. pylori-induced Infection in Gastric Mucosa
6.6.2. Related Conditions and Clinical Manifestations
6.7. Diagnosis
6.7.1. Noninvasive Tests
6.7.2. Invasive Methods
7. Patient Journey
8. Epidemiology and Patient Population
8.1. Key Findings
8.2. Assumptions and Rationale: The 7MM
8.2.1. Total Diagnosed Prevalent Cases of H. pylori Infection
8.2.2. Gender-specific Diagnosed Prevalent Cases of H. pylori Infection
8.2.3. Age-specific Diagnosed Prevalent Cases of H. pylori Infection
8.3. Total Diagnosed Prevalent Cases of H. pylori Infection in the 7MM
8.4. The US
8.4.1. Total Diagnosed Prevalent Cases of H. pylori Infection in the US
8.4.2. Gender-specific Diagnosed Prevalent Cases of H. pylori Infection in the US
8.4.3. Age-specific Diagnosed Prevalent Cases of H. pylori Infection in the US
8.5. EU4 and the UK
8.5.1. Total Diagnosed Prevalent Cases of H. pylori Infection in EU4 and the UK
8.5.2. Gender-specific Diagnosed Prevalent Cases of H. pylori Infection in EU4 and the UK
8.5.3. Age-specific Diagnosed Prevalent Cases of H. pylori Infection in EU4 and the UK
8.6. Japan
8.6.1. Total Diagnosed Prevalent Cases of H. pylori Infection in Japan
8.6.2. Gender-specific Diagnosed Prevalent Cases of H. pylori Infection in Japan
8.6.3. Age-specific Diagnosed Prevalent Cases of H. pylori Infection in Japan
9. KOL Views10. Unmet Needs
11. Appendix
11.1. Bibliography
11.2. Acronyms and Abbreviations
12.3. Report Methodology
12. Publisher Capabilities13. Disclaimer14. About the Publisher
List of Tables
Table 1: Summary of Epidemiology (2020-2034)
Table 2: Diagnostic Tests for H. pylori Infection
Table 3: Recommendations for H. pylori Infection Testing for Individuals and Populations (which individuals to test)
Table 4: Total Diagnosed Prevalent Cases of H. pylori Infection in the 7MM, in thousands (2020-2034)
Table 5: Total Diagnosed Prevalent Cases of H. pylori Infection in the US, in thousands (2020-2034)
Table 6: Gender-specific Diagnosed Prevalent Cases of H. pylori Infection in the US, in thousands (2020-2034)
Table 7: Age-specific Diagnosed Prevalent Cases of H. pylori Infection in the US, in thousands (2020-2034)
Table 8: Total Diagnosed Prevalent Cases of H. pylori Infection in EU4 and the UK, in thousands (2020-2034)
Table 9: Gender-specific Diagnosed Prevalent Cases of H. pylori Infection in EU4 and the UK, in thousands (2020-2034)
Table 10: Age-specific Diagnosed Prevalent Cases of H. pylori Infection in EU4 and the UK, in thousands (2020-2034)
Table 11: Total Prevalent Cases of H. pylori infection in Japan, in thousands (2020-2034)
Table 12: Gender-specific Diagnosed Prevalent Cases of H. pylori Infection in Japan, in thousands (2020-2034)
Table 13: Age-specific Diagnosed Prevalent Cases of H. pylori Infection in Japan, in thousands (2020-2034)
List of Figures
Figure 1: Entrance and lodging of H. pylori infection in the stomach
Figure 2: Symptoms of H. pylori Infection
Figure 3: Causes of H. pylori Infection
Figure 4: Risk Factors Associated with H. pylori infection
Figure 5: Routes of Transmission of H. pylori infection
Figure 6: Pathogenesis of H. pylori infection
Figure 7: Immunopathogenesis of H. pylori infection in Gastric Mucosa
Figure 8: Conditions associated with H. pylori infection
Figure 9: Patient Journey
Figure 10: Total Diagnosed Prevalent Cases of H. pylori infection in the 7MM (2020-2034)
Figure 11: Total Diagnosed Prevalent Cases of H. pylori infection in the US (2020-2034)
Figure 12: Gender-specific Diagnosed Prevalent Cases of H. pylori infection in the US (2020-2034)
Figure 13: Age-specific Diagnosed Prevalent Cases of H. pylori infection in the US (2020-2034)
Figure 14: Total Diagnosed Prevalent Cases of H. pylori infection in EU4 and the UK (2020-2034)
Figure 15: Gender-specific Diagnosed Prevalent Cases of H. pylori infection in EU4 and the UK (2020-2034)
Figure 16: Age-specific Diagnosed Prevalent Cases of H. pylori infection in EU4 and the UK (2020-2034)
Figure 17: Total Diagnosed Prevalent Cases of H. pylori infection in Japan (2020-2034)
Figure 18: Gender-specific Diagnosed Prevalent Cases of H. pylori infection in Japan (2020-2034)
Figure 19: Age-specific Diagnosed Prevalent Cases of H. pylori infection in Japan (2020-2034)
Figure 20: Unmet Needs