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Progressive Fibrosing Interstitial Lung Disease (pfild) - Epidemiology Forecast - 2032

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    Report

  • 90 Pages
  • August 2022
  • Region: Global
  • DelveInsight
  • ID: 5525597
This ‘Progressive Fibrosing Interstitial Lung Disease (PF-ILD)- Epidemiology Forecast-2032' report delivers an in-depth understanding of the Progressive Fibrosing Interstitial Lung Disease, historical and forecasted epidemiology as well as the PF-ILD trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan.

Progressive Fibrosing Interstitial Lung Disease Understanding

Progressive Fibrosing Interstitial Lung Disease (PF-ILD) consists of a diverse group of interstitial lung diseases (ILDs) characterized by a similar clinical phenotype of accelerated respiratory failure, frequent disease exacerbation and earlier mortality.

Interstitial lung disease is believed to be caused by long-term exposure to hazardous materials, such as asbestos or coal dust, or it can be caused by an auto-immune disease such as rheumatoid arthritis. Once lung scarring occurs, it is generally irreversible.

Progressive Fibrosing Interstitial Lung Diseases are composed of Idiopathic Interstitial Pneumonias such as non-specific interstitial pneumonia and unclassifiable interstitial pneumonia, and inhalation lung diseases such as chronic hypersensitivity pneumonia, and connective tissue disease-associated ILD such as rheumatoid arthritis-related ILD and SSc-related ILD, and sarcoidosis and so on. Many interstitial lung diseases (ILDs) are characterized by chronic progressive fibrosis. The type-specific segmentation majorly includes, Idiopathic Interstitial Pneumonias (IIPs), Autoimmune ILDs, Hypersensitivity Pneumonitis, Sarcoidosis, and other ILDs.

Progressive Fibrosing Interstitial Lung Disease Diagnosis

Imaging tests such as X-ray and a high-resolution computed tomography (CT scan), is key to, and sometimes the first step in, the diagnosis of interstitial lung disease. The severity level of Progressive Fibrosing Interstitial Lung Disease is calculated on the basis of FVC score. However, identifying and determining the cause of interstitial lung disease can be challenging, as a large number of disorders fall into this broad category. Hence differential diagnosis is needed.

The differential diagnosis of Interstitial Lung Diseases requires a multidisciplinary approach, usually involving pulmonologist, radiologist, and pathologist. The evaluations include clinical presentation, specific history assessment, smoking status, lung function evaluation, serological test results, imaging and if required, lung biopsy.

Progressive Fibrosing Interstitial Lung Disease Epidemiology Perspective

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Total Prevalent Cases of Interstitial Lung Disease (ILD), Total Diagnosed Prevalent Cases of Interstitial Lung Disease (ILD), Type-specific Diagnosed Prevalent Cases of Interstitial Lung Disease (ILD), Total Diagnosed Prevalent Cases of Progressive Fibrosing Interstitial Lung Disease (PF-ILD), in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan, from 2019 to 2032.

Progressive Fibrosing Interstitial Lung Disease Detailed Epidemiology Segmentation

  • In the assessment done by the publisher, the estimated total diagnosed prevalent cases of Progressive Fibrosing Interstitial Lung Disease (PF-ILD) in the 7MM were 322,197 in 2021.
  • The highest total diagnosed prevalent cases of Progressive Fibrosing Interstitial Lung Disease were accounted by the US in 2021 (166,393 cases), which are expected to show a rise in the future.
  • Among the European countries, Germany had the highest diagnosed prevalent cases of PF-ILD with 31,807 cases, followed by the United Kingdom, which had prevalent population of 25,446 in 2021. On the other hand, Spain had the lowest prevalent population (17,834 cases).
  • Japan had 31,542 total diagnosed prevalent cases of Progressive Fibrosing Interstitial Lung Disease in 2021, accounting for approximately 10% in 7MM.

Scope of the Report

  • The report covers the descriptive overview of Progressive Fibrosing Interstitial Lung Disease, explaining its symptoms, grading, pathophysiology, and various diagnostic approaches.
  • The report provides insight into the 7MM historical and forecasted patient pool covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), Japan.
  • The report assesses the disease risk and burden of Progressive Fibrosing Interstitial Lung Disease.
  • The report helps to recognize the growth opportunities in the 7MM with respect to the patient population.

Report Highlights

  • 11-Year Forecast of Progressive Fibrosing Interstitial Lung Disease
  • 7MM Coverage
  • Total Diagnosed Prevalent Cases of Progressive Fibrosing Interstitial Lung Disease

Key Questions Answered

  • What are the disease risk and burden of Progressive Fibrosing Interstitial Lung Disease?
  • What is the historical Progressive Fibrosing Interstitial Lung Disease patient pool in the United States, EU5 (Germany, France, Italy, Spain, and the UK), and Japan?
  • What would be the forecasted patient pool of Progressive Fibrosing Interstitial Lung Disease at the 7MM level?
  • What will be the growth opportunities across the 7MM with respect to the patient population pertaining to Progressive Fibrosing Interstitial Lung Disease?
  • Out of the above-mentioned countries, which country would have the highest prevalent population of Progressive Fibrosing Interstitial Lung Disease during the forecast period (2022-2032)?
  • At what CAGR the population is expected to grow across the 7MM during the forecast period (2022-2032)?

Reasons to Buy

The Progressive Fibrosing Interstitial Lung Disease report will allow the user to -
  • Develop business strategies by understanding the trends shaping and driving the 7MM+ Progressive Fibrosing Interstitial Lung Disease epidemiology forecast.
  • The Progressive Fibrosing Interstitial Lung Disease epidemiology report and model were written and developed by Masters and Ph.D. level epidemiologists.
  • The Progressive Fibrosing Interstitial Lung Disease epidemiology model developed by the publisher is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over the 11-year forecast period using reputable sources.

Key Assessments

  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of Disease by segmentation
  • Factors driving growth in a specific patient population

Geographies Covered

  • The United States
  • EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan
Study Period: 2019-2032

Table of Contents

1. Key Insights2. Report Introduction
3. Progressive Fibrosing Interstitial Lung Diseases (PF-ILD) Epidemiology Overview at a Glance
3.1. Patient Share (%) Distribution of PF-ILD in 2019
3.2. Patient Share (%) Distribution of PF-ILD in 2032
4. Executive Summary of Progressive Fibrosing Interstitial Lung Diseases (PF-ILD)
5. Disease Background and Overview: Progressive Fibrosing Interstitial Lung Disease (PF-ILD)
5.1. Introduction
5.2. Types of ILDs progressing into PF-ILD
5.2.1. IPF
5.2.2. Chronic hypersensitivity pneumonitis (HP)
5.2.3. Idiopathic nonspecific interstitial pneumonia (INSIP)
5.2.4. Unclassifiable idiopathic interstitial pneumonia (unclassifiable IIPs)
5.2.5. Autoimmune interstitial lung diseases (CTD-ILDs)
5.2.6. Rheumatoid arthritis-associated interstitial lung disease (RA-ILD)
5.2.7. SSc-ILD
5.2.8. Connective tissue disease less commonly associated with PF-ILD
5.2.9. Chronic sarcoidosis
5.2.10. Exposure-related ILDs
5.3. Pathogenesis of PF-ILD
5.4. Predictors of Disease Progression
5.5. Diagnosis of Progressive-Fibrosing Interstitial Lung Disease (PF-ILD)
5.6. Diagnostic Algorithm of PF-ILD
6. Epidemiology and Patient Population
6.1. Key Findings
6.2. Methodology of Epidemiology
6.3. Assumptions and Rationale: 7MM
6.3.1. United States
6.3.2. EU5 Countries
6.3.3. Japan
6.4. Total Diagnosed Prevalent Cases of Progressive Fibrosing Interstitial Lung Disease in the 7MM
6.5. Type-specific Diagnosed Prevalent Cases of Interstitial Lung Disease in the 7MM
6.6. The United States
6.6.1. Total Prevalent Cases of ILD in the United States
6.6.2. Total Diagnosed Prevalent Cases of ILD in the United States
6.6.3. Type-specific Diagnosed Prevalent Cases of ILD in the United States
6.6.4. Total Diagnosed Prevalent cases of PF-ILD in the United States
6.7. Major Five European Countries
6.7.1. Total Prevalent Cases of ILD in the EU5
6.7.2. Total Diagnosed Prevalent Cases of ILD in the EU5
6.7.3. Type-specific Diagnosed Prevalent Cases of ILD in the EU5
6.7.4. Total Diagnosed Prevalent cases of PF-ILD in the EU-5
6.8. Japan
6.8.1. Total Prevalent Cases of ILD in Japan
6.8.2. Total Diagnosed Prevalent Cases of ILD in Japan
6.8.3. Type-specific Diagnosed Prevalent Cases of ILD in Japan
6.8.4. Total Diagnosed Prevalent cases of PF-ILD in Japan
7. Patient Journey8. Key Opinion Leaders' Views
9. Appendix
9.1. Bibliography
9.2. Report Methodology
10. Publisher Capabilities11. Disclaimer12. About the Publisher
List of Tables
Table 1: Summary of PF-ILD Epidemiology (2019-2032)
Table 2: Total Diagnosed Prevalent cases of PF-ILD in the 7MM (2019-2032)
Table 3: Type-specific Diagnosed Prevalent Cases of ILD in the 7MM (2019-2032)
Table 4: Total Prevalent Cases of ILD in the US (2019-2032)
Table 5: Total Diagnosed Prevalent Cases of ILD in the US (2019-2032)
Table 6: Type-specific Diagnosed Prevalent Cases of ILD in the US (2019-2032)
Table 7: Total Diagnosed Prevalent Cases of PF-ILD in the US (2019-2032)
Table 8: Total Prevalent Cases of ILD in the EU5 (2019-2032)
Table 9: Total Diagnosed Prevalent Cases of ILD in the EU5 (2019-2032)
Table 10: Type-specific Diagnosed Prevalent Cases of ILD in Germany (2019-2032)
Table 11: Type-specific Diagnosed Prevalent Cases of ILD in France (2019-2032)
Table 12: Type-specific Diagnosed Prevalent Cases of ILD in Italy (2019-2032)
Table 13: Type-specific Diagnosed Prevalent Cases of ILD in Spain (2019-2032)
Table 14: Type-specific Diagnosed Prevalent Cases of ILD in the UK (2019-2032)
Table 15: Type-specific Diagnosed Prevalent Cases of ILD in the EU5 (2019-2032)
Table 16: Total Diagnosed Prevalent Cases of PF-ILD in the EU5 (2019-2032)
Table 17: Total Prevalent Cases of ILD in Japan (2019-2032)
Table 18: Total Diagnosed Prevalent Cases of ILD in Japan (2019-2032)
Table 19: Type-specific Diagnosed Prevalent Cases of ILD in Japan (2019-2032)
Table 20: List of Abbreviations
List of Figures
Figure 1: ILDs with Overlapping Area Shows the Probability of Having a Progressive-Fibrosing Phenotype
Figure 2: Known and Unknowns of PF-ILDs
Figure 3: Types of ILD Most Likely to Have a Progressive-fibrosing Phenotype
Figure 4: Fibrosis of the Alveolus Wall
Figure 5: Types of CTD-ILD
Figure 6: Concepts in the Pathogenesis of RA-ILD
Figure 7: Mechanisms Involved in the Pathogenesis and Progression of Fibrosing Interstitial Lung Diseases
Figure 8: Diagnosis of ILDs that may present a Progressive Phenotype
Figure 9: Total Diagnosed Prevalent Cases of PF-ILD in the 7MM (2019-2032)
Figure 10: Type-specific Diagnosed Prevalent Cases of ILD in the 7MM (2019-2032)
Figure 11: Total Prevalent Cases of ILD in the US (2019-2032)
Figure 12: Total Diagnosed Prevalent Cases of ILD in the US (2019-2032)
Figure 13: Type-specific Diagnosed Prevalent Cases of ILD in the US (2019-2032)
Figure 14: Total Diagnosed Prevalent Cases of PF-ILD in the US (2019-2032)
Figure 15: Total Prevalent Cases of ILD in the EU5 (2019-2032)
Figure 16: Total Diagnosed Prevalent Cases of ILD in the EU5 (2019-2032)
Figure 17: Type-specific Diagnosed Prevalent Cases of ILD in the EU5 (2019-2032)
Figure 18: Total Diagnosed Prevalent Cases of PF-ILD in the EU5 (2019-2032)
Figure 19: Total Prevalent Cases of ILD in Japan (2019-2032)
Figure 20: Total Diagnosed Prevalent Cases of ILD in Japan (2019-2032)
Figure 21: Type-specific Diagnosed Prevalent Cases of ILD in Japan (2019-2032)
Figure 22: Total Diagnosed Prevalent Cases of PF-ILD in Japan (2019-2032)
Figure 23: Patient Journey