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Frontotemporal Dementia (FTD) - Epidemiology Forecast - 2032

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    Report

  • 79 Pages
  • September 2022
  • Region: Global
  • DelveInsight
  • ID: 5525871
This ‘Frontotemporal Dementia (FTD) - Epidemiology Forecast-2032' report delivers an in-depth understanding of FTD, historical and forecasted epidemiology as well as FTD trends in the United States, the EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan.

Frontotemporal Dementia Disease Understanding

FTD is a term used to describe a group of neurocognitive disorders that encompass progressive dysfunction in executive functioning, behavior, and language. There are three types of frontotemporal disorders (FTD): behavioral variant frontotemporal dementia (bvFTD), primary progressive aphasia (PPA), and movement disorders.

FTD occurs when brain cells in the frontal or temporal lobes die due to the build-up of abnormal proteins, leading to abnormal brain function, and more cell deaths result in brain atrophy. Many possible symptoms can result, including unusual behaviors, emotional problems, trouble communicating, difficulty with work, or difficulty with walking.

Frontotemporal Dementia Diagnosis

FTD can be hard to diagnose as it displays clinical symptoms that can be mistaken for other dementias or psychiatric disorders. The average time from symptom onset to accurate diagnosis is about 3.6 years. Diagnosis of FTD currently includes Imaging and blood or cerebrospinal fluid studies.

A ‘definite' diagnosis of FTD is still based on neuropathology confirmation postmortem. Diagnostic markers currently used for FTD include imaging and blood or cerebrospinal fluid studies. They may best serve a diagnostic role when used in a multimodal approach to achieve a ‘definite' diagnosis of FTD in the living patient as soon as possible.

Frontotemporal Dementia Epidemiology Perspective

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Diagnosed Prevalent Cases of Frontotemporal Dementia (FTD), Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia (FTD) and Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia (FTD) in the 7MM covering the United States, the EU5 countries (Germany, France, Italy, Spain, and the United Kingdom) and Japan from 2019 to 2032.

Key Findings

  • Total diagnosed prevalent cases of FTD in the 7MM was found to be 128,570 in 2021, which might increase by the end of 2032. These cases are expected to increase at a CAGR of 0.3% during study period (2019-2032).
  • Among 7MM, the United States has the highest prevalent cases of FTD with 58,960 cases in 2021.
  • On the basis of type-specific diagnosed prevalent cases of FTD, bvFTD accounted for highest number of cases in 2021 with 35,846 cases in the United States.
  • Among the European countries, Germany had the highest diagnosed prevalent population of FTD with 14,856 cases, followed by the France with 11,983 cases in 2021. On the other hand, Spain had the lowest diagnosed prevalent population.
  • Japan accounted for 11,845 diagnosed prevalent cases of FTD in the year 2021 which are expected to decrease during the forecasted period (2022-2032).

Scope of the Report

  • The report covers the descriptive overview of FTD, explaining its symptoms, etiology, pathogenesis, and various diagnostic approaches.
  • The report provides insight into the 7MM historical and forecasted patient pool covering the United States, EU5 countries (Germany, France, Italy, Spain, and the United Kingdom), and Japan.
  • The report assesses the disease risk and burden of FTD.
  • The report helps to recognize the growth opportunities in the 7MM with respect to the patient population.
  • The report provides the segmentation of the disease epidemiology for 7MM diagnosed prevalent cases of frontotemporal dementia, type-specific diagnosed prevalent cases of frontotemporal dementia, and gene-specific diagnosed prevalent cases of frontotemporal dementia.

Report Highlights

  • 11-Year Forecast of Frontotemporal Dementia
  • The 7MM Coverage
  • Total diagnosed prevalent cases of Frontotemporal Dementia
  • Type-specific prevalent cases of Frontotemporal Dementia
  • Gene-specific prevalent cases of Frontotemporal Dementia

Key Questions Answered

  • What are the disease risk and burdens of Frontotemporal Dementia?
  • What is the historical Frontotemporal Dementia patient pool in the United States, the EU5 (Germany, France, Italy, Spain, and the UK), and Japan?
  • What would be the forecasted patient pool of Frontotemporal Dementia at the 7MM level?
  • What will be the growth opportunities across the 7MM concerning the patient population about Frontotemporal Dementia?
  • Out of the above-mentioned countries, which country would have the highest diagnosed prevalent population of Frontotemporal Dementia during the forecast period (2022-2032)?
  • At what CAGR the population is expected to grow across the 7MM during the forecast period (2022-2032)?

Reasons to Buy

The Frontotemporal Dementia report will allow the user to -
  • Develop business strategies by understanding the trends shaping and driving the 7MM Frontotemporal Dementia epidemiology forecast.
  • The Frontotemporal Dementia epidemiology report and model were written and developed by Masters and Ph.D. level epidemiologists.
  • The Frontotemporal Dementia epidemiology model developed by the publisher is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over the 11-year forecast period using reputable sources.

Key Assessments

  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of disease by the segmentation
  • Factors driving growth in a specific patient population

Geographies Covered

  • The United States
  • The EU5 (Germany, France, Italy, Spain, and the United Kingdom)
  • Japan
Study Period: 2019-2032

Table of Contents

1. Key Insights2. Report Introduction
3. Frontotemporal Dementia (FTD) Patient Overview at a Glance
3.1. Patient Share (%) Distribution of Frontotemporal Dementia in 2019
3.2. Patient Share (%) Distribution of Frontotemporal Dementia in 2032
4. Patient Journey5. Executive Summary of Frontotemporal Dementia
6. Disease Background and Overview: Frontotemporal Dementia
6.1. Introduction
6.2. Clinical Manifestations
6.3. Causes
6.4. Pathophysiology
6.5. Genetics
6.6. Related FTD Syndromes
6.7. Diagnosis
6.7.1. Diagnostic Algorithm
6.7.2. Diagnostic Guidelines
7. Epidemiology and Patient Population
7.1. Key Findings
7.2. Methodology of Epidemiology
7.3. Assumptions and Rationale: 7MM
7.4. Total Diagnosed Prevalent Cases of Frontotemporal Dementia in the 7MM
7.5. The United States
7.5.1. Diagnosed Prevalent Cases of Frontotemporal Dementia in the United States
7.5.2. Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the United States
7.5.3. Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the United States
7.6. Major Five European Countries
7.6.1. Germany
7.6.1.1. Diagnosed Prevalent Cases of Frontotemporal Dementia in Germany
7.6.1.2. Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Germany
7.6.1.3. Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Germany
7.6.2. France
7.6.2.1. Diagnosed Prevalent Cases of Frontotemporal Dementia in France
7.6.2.2. Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in France
7.6.2.3. Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in France
7.6.3. Italy
7.6.3.1. Diagnosed Prevalent Cases of Frontotemporal Dementia in Italy
7.6.3.2. Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Italy
7.6.3.3. Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Italy
7.6.4. Spain
7.6.4.1. Diagnosed Prevalent Cases of Frontotemporal Dementia in Spain
7.6.4.2. Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Spain
7.6.4.3. Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Spain
7.6.5. The United Kingdom
7.6.5.1. Diagnosed Prevalent Cases of Frontotemporal Dementia in the United Kingdom
7.6.5.2. Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the United Kingdom
7.6.5.3. Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the United Kingdom
7.7. Japan
7.7.1. Diagnosed Prevalent Cases of Frontotemporal Dementia in Japan
7.7.2. Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Japan
7.7.3. Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Japan
8. Appendix
8.1. Bibliography
8.2. Abbreviation
8.3. Report Methodology
9. Publisher Capabilities10. Disclaimer11. About the Publisher
List of Tables
Table 1: Summary of Frontotemporal Dementia Epidemiology (2019-2032)
Table 2: FTD Neuroimaging Correlations
Table 3: Diagnostic Markers in Current Use in FTD
Table 4: Diagnostic Behavioural and Language Features of FTD Variants
Table 5: Total Diagnosed Prevalent Cases of Frontotemporal Dementia in the 7MM (2019-2032)
Table 6: Diagnosed Prevalent Cases of Frontotemporal Dementia in the United States (2019-2032)
Table 7: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the United States (2019-2032)
Table 8: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the United States (2019-2032)
Table 9: Diagnosed Prevalent Cases of Frontotemporal Dementia in Germany (2019-2032)
Table 10: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Germany(2019-2032)
Table 11: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Germany (2019-2032)
Table 12: Diagnosed Prevalent Cases of Frontotemporal Dementia in France (2019-2032)
Table 13: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in France (2019-2032)
Table 14: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in France(2019-2032)
Table 15: Diagnosed Prevalent Cases of Frontotemporal Dementia in Italy (2019-2032)
Table 16: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Italy (2019-2032)
Table 17: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Italy(2019-2032)
Table 18: Diagnosed Prevalent Cases of Frontotemporal Dementia in Spain (2019-2032)
Table 19: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Spain (2019-2032)
Table 20: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Spain (2019-2032)
Table 21: Diagnosed Prevalent Cases of Frontotemporal Dementia in the UK (2019-2032)
Table 22: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the UK(2019-2032)
Table 23: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the UK(2019-2032)
Table 24: Diagnosed Prevalent Cases of Frontotemporal Dementia in Japan (2019-2032)
Table 25: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Japan (2019-2032)
Table 26: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Japan (2019-2032)
Table 27: Abbreviations
List of Figures
Figure 1: FTD
Figure 2: Parts of Brain
Figure 3: Clinical Subtypes of FTD
Figure 4: Interstitial fibrosis
Figure 5: Standard Assessment Protocol in FTD
Figure 6: Total Diagnosed Prevalent Cases of Frontotemporal Dementia in the 7MM (2019-2032)
Figure 7: Diagnosed Prevalent Cases of Frontotemporal Dementia in the United States (2019-2032)
Figure 8: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the United States (2019-2032)
Figure 9: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the United States (2019-2032)
Figure 10: Diagnosed Prevalent Cases of Frontotemporal Dementia in Germany (2019-2032)
Figure 11: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Germany(2019-2032)
Figure 12: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Germany (2019-2032)
Figure 13: Diagnosed Prevalent Cases of Frontotemporal Dementia in France (2019-2032)
Figure 14: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in France (2019-2032)
Figure 15: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in France(2019-2032)
Figure 16: Diagnosed Prevalent Cases of Frontotemporal Dementia in Italy (2019-2032)
Figure 17: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Italy (2019-2032)
Figure 18: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Italy(2019-2032)
Figure 19: Diagnosed Prevalent Cases of Frontotemporal Dementia in Spain (2019-2032)
Figure 20: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Spain (2019-2032)
Figure 21: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Spain (2019-2032)
Figure 22: Diagnosed Prevalent Cases of Frontotemporal Dementia in the UK (2019-2032)
Figure 23: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the UK(2019-2032)
Figure 24: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in the UK(2019-2032)
Figure 25: Diagnosed Prevalent Cases of Frontotemporal Dementia in Japan (2019-2032)
Figure 26: Type-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Japan (2019-2032)
Figure 27: Gene-specific Diagnosed Prevalent Cases of Frontotemporal Dementia in Japan (2019-2032)
Figure 28: Patient Journey