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Dilated Cardiomyopathy Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update

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    Report

  • 80 Pages
  • February 2022
  • Region: Global
  • Global Markets Direct
  • ID: 5553779
1h Free Analyst Time
1h Free Analyst Time

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This pipeline guide Dilated Cardiomyopathy Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update, provides an overview of the Dilated Cardiomyopathy (Cardiovascular) pipeline landscape.

Dilated cardiomyopathy (DCM) is a condition in which the heart's ability to pump blood is decreased because the heart's main pumping chamber, the left ventricle, is enlarged and weakened. Symptoms include Fatigue and weakness, Shortness of breath (dyspnea), light-headedness, dizziness or fainting, persistent cough or wheezing, lack of appetite, sudden weight gain from fluid retention and swelling (edema) in legs, ankles and feet. Risk factors include family history, alcoholism, hypertension, cocaine abuse and metabolic disorders, such as thyroid disease or diabetes.

Report Highlights


This pipeline guide Dilated Cardiomyopathy Drugs in Development by Stages, Target, MoA, RoA, Molecule Type and Key Players, 2022 Update, provides comprehensive information on the therapeutics under development for Dilated Cardiomyopathy (Cardiovascular), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Dilated Cardiomyopathy (Cardiovascular) pipeline guide also reviews of key players involved in therapeutic development for Dilated Cardiomyopathy and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, Phase 0, Preclinical and Discovery stages are 1, 4, 2, 1, 10 and 13 respectively. Similarly, the Universities portfolio in Preclinical stages comprises 1 molecules, respectively.

Dilated Cardiomyopathy (Cardiovascular) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope


  • The pipeline guide provides a snapshot of the global therapeutic landscape of Dilated Cardiomyopathy (Cardiovascular).
  • The pipeline guide reviews pipeline therapeutics for Dilated Cardiomyopathy (Cardiovascular) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Dilated Cardiomyopathy (Cardiovascular) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Dilated Cardiomyopathy (Cardiovascular) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Dilated Cardiomyopathy (Cardiovascular)

Reasons to Buy


  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Dilated Cardiomyopathy (Cardiovascular).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Dilated Cardiomyopathy (Cardiovascular) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

IntroductionReport CoverageOverview
Therapeutics Development
  • Pipeline Overview
  • Pipeline by Companies
  • Pipeline by Universities/Institutes
  • Products under Development by Companies
  • Products under Development by Universities/Institutes

Therapeutics Assessment
  • Assessment by Target
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type

Companies Involved in Therapeutics Development
  • Avery Therapeutics Inc
  • Berlin Cures Holding AG
  • BioMarin Pharmaceutical Inc
  • BridgeBio Pharma Inc
  • Bristol-Myers Squibb Co
  • Cardior Pharmaceuticals GmbH
  • Celixir Ltd
  • CellServe GmbH
  • DiNAQOR AG
  • Dynomics Inc
  • Heartseed Inc
  • Help Therapeutics
  • iHeart Japan Corp
  • Martin Pharmaceuticals Inc
  • Maze Therapeutics Inc
  • NeoProgen Inc
  • Nuevocor Pte Ltd
  • Olagenesis Corp
  • Pfizer Inc
  • Recursion Pharmaceuticals Inc
  • Renovacor Inc
  • Shionogi & Co Ltd
  • Tenaya Therapeutics Inc

Drug Profiles
  • BC-007 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • CDR-426D - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Cell Therapy for Dilated Cardiomyopathy - Drug Profile
  • Product Description
  • Mechanism Of Action
  • danicamtiv - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • DINA-005 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • DINA-006 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • DINA-008 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • DINA-009 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • DINA-010 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • DINA-011 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • DYN-101 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • emprumapimod - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • Gene Therapy for Dilated Cardiomyopathy - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Gene Therapy for Dilated Cardiomyopathy - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Gene Therapy for Dilated Cardiomyopathy - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • Gene Therapy for Dilated Cardiomyopathy and Heart Failure - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Gene Therapy to Activate BAG3 for Dilated Cardiomyopathy - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Heartcel - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • HS-001 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • IHJ-301 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • MyCardia - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Neo-2001 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • NovoCardia - Drug Profile
  • Product Description
  • Mechanism Of Action
  • redasemtide trifluoroacetate - Drug Profile
  • Product Description
  • Mechanism Of Action
  • REN-001 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • Small Molecule for Dilated Cardiomyopathy - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Small Molecules for Dilated Cardiomyopathy - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Small Molecules for Dilated Cardiomyopathy - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • Stem Cell Therapy for Myocardial Infarction and Dilated Cardiomyopathy - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • TN-301 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • trimetazidine - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • YS-1402 - Drug Profile
  • Product Description
  • Mechanism Of Action

Dormant ProjectsProduct Development Milestones
Featured News & Press Releases
  • Jul 13, 2021: Tenaya Therapeutics unveils preclinical research supporting product candidate for rare and prevalent heart disease indications at ESC Heart Failure 2021
  • Sep 09, 2020: MyoKardia doses first patient in phase 2 clinical trial of danicamtiv in genetic dilated cardiomyopathy
  • Mar 26, 2020: MyoKardia Provides clinical trial update on Danicamtiv study
  • Oct 28, 2019: MyoKardia Announces Positive MYK-491 Data; Advancing Program into Targeted Genetic Dilated Cardiomyopathy Population
  • May 30, 2019: MyoKardia’s MYK-491 shows favourable profile in Phase Ia study
  • Apr 15, 2019: Berlin Cures announces start of Phase IIa for its DNA-based neutralizer of ß1-adrenoceptor autoantibodies
  • Dec 11, 2018: MyoKardia reports positive data from phase 1b single-ascending dose clinical trial of MYK-491 in dilated cardiomyopathy and systolic heart failure patients
  • Dec 06, 2018: Berlin Cures steering committee is assembled to facilitate the design and implementation of phase 2 study of BC 007
  • Oct 30, 2018: MyoKardia Shares Data from new research program ACT-1 at 2018 R&D Day
  • Feb 26, 2018: Heart Failure Treatment from Berlin Cures Shows Promise in Phase 1 Study
  • Feb 14, 2018: MyoKardia Begins Patient Dosing in Phase 1b Clinical Study of MYK-491 in Dilated Cardiomyopathy Patients
  • Nov 02, 2017: MyoKardia Provides Update on MYK-491
  • Sep 27, 2017: MyoKardia Provides Update on MYK-491 Clinical Progress
  • Feb 02, 2017: First Subjects Dosed in MyoKardia Phase 1 Study of Dilated Cardiomyopathy Candidate MYK-491
  • Dec 02, 2016: MyoKardia Announces Receipt of Milestone Payment from Sanofi for DCM Candidate MYK-491

Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact the Analyst
  • Disclaimer

List of Tables
  • Number of Products under Development for Dilated Cardiomyopathy, 2022
  • Number of Products under Development by Companies, 2022
  • Number of Products under Development by Universities/Institutes, 2022
  • Products under Development by Companies, 2022
  • Products under Development by Universities/Institutes, 2022
  • Number of Products by Stage and Target, 2022
  • Number of Products by Stage and Mechanism of Action, 2022
  • Number of Products by Stage and Route of Administration, 2022
  • Number of Products by Stage and Molecule Type, 2022
  • Dilated Cardiomyopathy - Pipeline by Avery Therapeutics Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by Berlin Cures Holding AG, 2022
  • Dilated Cardiomyopathy - Pipeline by BioMarin Pharmaceutical Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by BridgeBio Pharma Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by Bristol-Myers Squibb Co, 2022
  • Dilated Cardiomyopathy - Pipeline by Cardior Pharmaceuticals GmbH, 2022
  • Dilated Cardiomyopathy - Pipeline by Celixir Ltd, 2022
  • Dilated Cardiomyopathy - Pipeline by CellServe GmbH, 2022
  • Dilated Cardiomyopathy - Pipeline by DiNAQOR AG, 2022
  • Dilated Cardiomyopathy - Pipeline by Dynomics Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by Heartseed Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by Help Therapeutics, 2022
  • Dilated Cardiomyopathy - Pipeline by iHeart Japan Corp, 2022
  • Dilated Cardiomyopathy - Pipeline by Martin Pharmaceuticals Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by Maze Therapeutics Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by NeoProgen Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by Nuevocor Pte Ltd, 2022
  • Dilated Cardiomyopathy - Pipeline by Olagenesis Corp, 2022
  • Dilated Cardiomyopathy - Pipeline by Pfizer Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by Recursion Pharmaceuticals Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by Renovacor Inc, 2022
  • Dilated Cardiomyopathy - Pipeline by Shionogi & Co Ltd, 2022
  • Dilated Cardiomyopathy - Pipeline by Tenaya Therapeutics Inc, 2022
  • Dilated Cardiomyopathy - Dormant Projects, 2022

List of Figures
  • Number of Products under Development for Dilated Cardiomyopathy, 2022
  • Number of Products under Development by Companies, 2022
  • Number of Products by Targets, 2022
  • Number of Products by Stage and Targets, 2022
  • Number of Products by Mechanism of Actions, 2022
  • Number of Products by Stage and Mechanism of Actions, 2022
  • Number of Products by Routes of Administration, 2022
  • Number of Products by Stage and Routes of Administration, 2022
  • Number of Products by Molecule Types, 2022
  • Number of Products by Stage and Molecule Types, 2022

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Avery Therapeutics Inc
  • Berlin Cures Holding AG
  • BioMarin Pharmaceutical Inc
  • BridgeBio Pharma Inc
  • Bristol-Myers Squibb Co
  • Cardior Pharmaceuticals GmbH
  • Celixir Ltd
  • CellServe GmbH
  • DiNAQOR AG
  • Dynomics Inc
  • Heartseed Inc
  • Help Therapeutics
  • iHeart Japan Corp
  • Martin Pharmaceuticals Inc
  • Maze Therapeutics Inc
  • NeoProgen Inc
  • Nuevocor Pte Ltd
  • Olagenesis Corp
  • Pfizer Inc
  • Recursion Pharmaceuticals Inc
  • Renovacor Inc
  • Shionogi & Co Ltd
  • Tenaya Therapeutics Inc