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Epigenetics of Metabolism. Translational Epigenetics

  • Book
  • September 2022
  • Elsevier Science and Technology
  • ID: 5561981

Epigenetics of Metabolism, a new volume in the Translational Epigenetics series, comprehensively explores epigenetic changes and the regulation of nutrient metabolism related to human development and disease. Here, international leaders in the field provide a broad overview of epigenetics in bodily and cellular metabolism, including epigenetic mechanisms involved in the metabolism of carbohydrates, proteins and lipids, as well as in related diseases. Also discussed are the roles of vitamins and minerals in epigenetics of metabolism, epigenetic changes in deficiency or toxicity of micronutrients, and the effects of natural plants, phytochemicals and intestinal bacteria.

This book offers researchers, students and health care practitioners a full grounding in nutrient-gene interactions in metabolism, with applied knowledge, research methods and protocols, and clinical pathways to drive new discovery and medical outcomes.

Table of Contents

Section 1. Epigenetics in Macronutrient Metabolism 1. Carbohydrates Metabolism and Epigenetics 3. Lipids Metabolism and Epigenetics

Section 2. Roles of Micronutrient in Epigenetics of Metabolism 4. Roles of Water-Soluble Vitamins in Epigenetics of Metabolism 5. Roles of Fat-Soluble Vitamins in Epigenetics of Metabolism 6. Roles of Major Minerals in Epigenetics of Metabolism 7. Roles of Trace Minerals in Epigenetics of Metabolism

Section 3. Effects of Natural Plants or Phytochemicals on Epigenetic Changes in Disease 8. Effects of Natural Plants or Phytochemicals on Epigenetic Changes in Obesity 9. Effects of Natural Plants or Phytochemicals on Epigenetic Changes in Diabetes 10. Effects of Natural Plants or Phytochemicals on Epigenetic Changes in Cardiovascular Diseases 11. Effects of Natural Plants or Phytochemicals on Epigenetic Changes in Liver Diseases 12. Effects of Natural Plants or Phytochemicals on Epigenetic Changes in Kidney Diseases 13. Effects of Natural Plants or Phytochemicals on Epigenetic Changes in Autoimmune Diseases 14. Effects of Natural Plants or Phytochemicals on Epigenetic Changes in Cancer

Section 4. Effects of Intestinal Bacteria on Epigenetic Changes in Diseases 15. Effects of Intestinal Bacteria on Epigenetic Changes in Inflammatory Diseases 16. Effects of Intestinal Bacteria on Epigenetic Changes in Chronic Diseases 17. Effects of Intestinal Bacteria on Epigenetic Changes in Cancer

Section 5. Research Methods in Epigenetics 18. Detection of DNA Methylation 19. Detection of Histone Modification 20. Detection of Non-coding RNAs

Authors

Yuan-Xiang Pan Associate Professor, Department of Food Science and Human Nutrition (FSHN), a member of the Division of Nutritional Sciences (DNS) and Illinois Informatics Institute (I3), University of Illinois, Urbana-Champaign (UIUC), USA. He graduated with a B.S. degree in cell biology from Lanzhou University and received both his M.S. and Ph.D. in Animal Nutrition from Virginia Tech where he studied protein metabolism. He completed his postdoctoral training in nutritional control of mammalian gene expression at the University of Florida, College of Medicine. Dr. Pan's research is to understand the adaptation of epigenetic modifications in mammalian gene regulation to the environment changes, with a focus on the impact of these adaptive processes in health and disease. Dr. Pan has over 65 peer-reviewed publications and receives grant support from the NIH, the United States Department of Agriculture, and industry. Shasha Zheng Associate Professor of Nutrition, Head of MS Program in Human Molecular and Medical Nutrition, College of Health Science, California Baptist University, Riverside, CA, USA. The recipient of various NIH grants, Dr. Zheng's current research projects include the discovery of the novel SUMOylation inhibitor as anti-influenza virus agent; the impact of Native American plants as therapeutic supplements on the prevention and treatment of hypertension, hyperlipidemia, and chronic inflammatory diseases; immunological consequences of transcription factor interactions; and the effects of maternal supplements on fetal developmental programing and offspring health outcomes. She has published in such peer reviewed journals as the Journal of Cellular Biochemistry, International Journal of Public Health Science, Journal of Nutrition and Food Sciences, Journal of Immunology, Molecular and Cell Biology, and Epigenetics.?