A Clinical Guide to Inositols

Table of Contents

1. Introducing inositols and their clinical targets: physiology and pathophysiology
2. Effectiveness of Myo- and D-chiro-inositol in the treatment of metabolic disorders
3. Treating PCOS with inositols: choosing the most appropriate myo- to D-chiro-inositol ratio
4. Overcoming inositol-resistance
5. Inositol supplementation for preventing Gestational Diabetes Mellitus
6. Inositol efficacy on the incidence of adverse fetal outcomes
7. Treatments with inositols in the IVF procedures
8. Supplementation with D-chiro-inositol in women
9. Application of myo-inositol and D-chiro-inositol in andrological issues
10. Myo-inositol supplementation for subclinical hypothyroidism
11. Respiratory distress and treatment with Myo-inositol to reduce pulmonary inflammation
12. Inositols as adjuvant treatments in oncology
13. Myo-inositol supplementation restores inositol depletion induced by treatments for psychiatric and neurological conditions

Authors

Vittorio Unfer Professor, University of Modena and Reggio Emilia, Italy. Vittorio Unfer, MD, is a Professor at the Faculty of Medicine of the University of Modena and Reggio Emilia, Italy, and also works as an Obstetrics and Gynecology specialist, researcher and university lecturer. His research interests include aspects of nutrition and use of food supplements in obstetrics and gynecology clinical practice and the morphofunctional study of uterine contractile activity with previous uterine scar, the triggering mechanisms of labor, the treatment of the threatened miscarriage abortion and prevention of preterm labor in high-risk patients, the treatment of hypogonadotropic male hypogonadism with FSH, and several in-depth and comparative experimentations on the fetal maturity. Prof. Unfer was one of the first researchers studying the use of myo-inositol in the treatment for polycystic ovary syndrome; his in-depth research pointed out the beneficial effects of the myo-inositol molecule on ovarian function and metabolic parameters. He has published numerous articles in reputed journals, including Fertility and Sterility and International Journal of Molecular Sciences. Didier Dewailly Professor, Endocrinology, Reproductive Medicine, Lille University Hospital, France. Dr Didier Dewailly is professor of Endocrinology and Reproductive Medicine in the Lille University Hospital, France. Until 2017, he was head of the Department of Endocrine Gynecology and Reproductive Medicine at the H�pital Jeanne de Flandre, including an IVF unit. He is now retired from the Hospital, but he still keeps an academic position and coordinates the teaching of Medical Gynecology and Reproductive Medicine for the North-West area of France. He is redactor-in-chief of M�decine-Th�rapeutique/M�decine de la Reproduction which is the journal of the French Reproductive Medicine Society whom he is past-President. His main fields of interest in research currently are the female hyperandrogenism (Polycystic Ovary Syndrome (PCOS) and other causes) and Ovulation Disorders such as PCOS, hypothalamic amenorrhea, hypogonadotropic hypogonadism and premature ovarian failure.