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Cell Based Assay & High Content Screening Markets. Forecasts by User and Product. With Executive and Consultant Guides. 2023 to 2027

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    Report

  • 295 Pages
  • September 2023
  • Region: Global
  • Howe Sound Research
  • ID: 5572427

Post pandemic conditions bode well for Cell Based Assay and High Content Screening Markets

Cell Based Assays are a mainstay of drug development and scientific research, and now, post pandemic, research activity is taking off. On top of this new technology is allowing Cell Based Assays to be used to measure any aspect of cell function. This market just keeps on growing with no end in sight. The workhorse of the pharmaceutical industry is becoming a central player in biotechnology.

This is a complex area but this readable report will bring the entire management team up to speed, on both the technology and the opportunity. The technology is moving faster than the market. Genomics and Immunology are playing a role too. Find the opportunities and the pitfalls. Understand growth expectations and the ultimate potential market size.

Table of Contents

1. Market Guides  
1.1 Situation Analysis  
1.2 Guide for Executives and Marketing Staff  
1.3 Guide for Investment Analysts and Management Consultants  

2. Introduction and Market Definition  
2.1 What are Cell Based Assays?  
2.2 Clinical Trial Failures  
2.2.1 Immuno-oncology Plays a Leading Role in Cell Based Assays  
2.3 Infectious Disease Will Play a Larger Role  
2.4 Market Definition  
2.4.1 Market Size  
2.4.2 Currency  
2.4.3 Years  
2.5 Methodology  
2.5.1 Authors  
2.5.2 Sources  
2.6 U.S. Medical Market and Pharmaceutical Research Spending - Perspective  
1.5.1 U.S. Expenditures for Pharmaceutical Research  

3. Cell Based Assays -  Guide to Technology  
3.1 Cell Cultures  
3.1.1 Cell Lines  
3.1.2 Primary Cells  
3.1.3 Stem Cells  
3.1.4 iPSC’s -  The Special Case  
3.2 Cell Assays  
3.3 Cell Viability Assays  
3.4 Cell Proliferation Assays  
3.5 Cytotoxicity Assays  
3.6 Cell Senescence Assays  
3.7 Apoptosis  
3.8 Autophagy  
3.9 Necrosis  
3.10 Oxidative Stress  
3.11 2D vs. 3D  
3.12 Signalling Pathways, GPCR  
3.13 Immune Regulation & Inhibition  
3.14 Reporter Gene Technology  
3.15 CBA Design & Development  
3.16 Cell Based Assays -  The Takeaway  

4. Industry Overview  
4.1 Players in a Dynamic Market  
4.1.1 Academic Research Lab  
4.1.2 Contract Research Organization  
4.1.3 Genomic Instrumentation Supplier  
4.1.4 Cell Separation and Viewing Supplier  
4.1.5 Cell Line and Reagent Supplier  
4.1.6 Pharmaceutical Company  
4.1.7 Audit Body  
4.1.8 Certification Body 

5. Market Trends  
5.1 Factors Driving Growth  
5.1.1 Candidate Growth  
5.1.2 Immuno-oncology  
5.1.3 Genomic Blizzard  
5.1.4 Technology Convergence  
5.1.5 The Insurance Effect  
5.2 Factors Limiting Growth  
5.2.1 CBA Development Challenges  
5.2.2 Instrument Integration  
5.2.3 Protocols  
5.3  Technology Development  
5.3.1 3D Assays  
5.3.2 Automation  
5.3.3 Software  
5.3.4 Primary Cells  
5.3.5 Signaling and Reporter Genes  
5.3.6 The Next Five Years 

6. Cell Based Assays Recent Developments  
6.1 Recent Developments - Importance and How to Use This Section
6.1.1 Importance of These Developments
6.1.2 How to Use This Section  
6.2 Charles River Laboratories Acquires SAMDI Tech  
6.3 Axion BioSystems Launches New High-Throughput Live-Cell Imaging Platform  
6.4 Fujifilm’s Life Sciences Invests in PhenoVista Biosciences  
6.5 Nucleai Launches New Multiplex Imaging Spatial Analysis Solution
6.6 BIO-TECHNE ANNOUNCES MULTI-OMIC RNASCOPE ASSAYS
6.7 Indivumed, CellPhenomics Partner on Cancer Drug Target Research
6.8 Synthego to Accelerate Drug Discovery
6.9 Long COVID Detected By Cell-Based Assay  
6.10 Nanolive closes a USD 20 million Funding Round 
6.11 Depixus Seeks to Commercialize 'Magnetic Tweezers' for Drug Discovery 
6.12 BioAuxilium Research Expands its Cell Signaling Assay Portfolio
6.13 Droplet Genomics Debuts New Microfluidic Screening Platform 
6.14 DLP Plus Single-Cell Sequencing Method Spreads From Canada to Cancer Labs Worldwide
6.15 Secondcell Bio to Make Creation of Cell Lines Easy 
6.16 Nanolitre‐scale cell assays developed with droplet microarraymass spec 
6.17 Thermo Fisher Scientific Acquires Cell Sorting Technology
6.18 Cellink to Distribute Phasefocus High-Content Cell Imaging Platform
6.19 Axxam and FUJIFILM Cellular Dynamics Announce Strategic Alliance
6.20 Cancer Genetics to Acquire Organoid Startup Stemonix  
6.21 Curi Bio Acquires Artificial Intelligence Firm Dana Solutions 
6.22 CRISPR Screens Uncover Novel Cancer Therapy Targets 
6.23 ERS Genomics Licenses CRISPR-Cas9 Patents to Axxam
6.24 New Transcriptomics Assay Facilitates Compound Screens  
6.25 Carta Biosciences Betting on Gene Interaction Mapping
6.26 High-throughput Identifies cancer drug candidates  
6.27 Velabs Therapeutics partners with Alytas Therapeutics to develop a novel immune-based therapy for obesity 
6.28 InSphero platform selected to test Cyclerion's sGC stimulator technology  
6.29 OcellO to provide in vitro research services to Merus
6.30 Charles River Laboratories to acquire Citoxlab 
6.31 Reaction Biology Corporation Purchases ProQinase GmbH  

7. Profiles of Key Cell Based Assay Companies  
7.1 Abcam 
7.2 Agilent/Dako
7.3 Aurora Biomed  
7.4 Axxam
7.5 Beckman Coulter Diagnostics
7.6 Becton, Dickinson and Company  
7.7 Berkley Lights
7.8 BioIVT  
7.9 Bio-Rad Laboratories, Inc. 
7.10 BioTek Instruments
7.11 BioVision, Inc.
7.12 BMG Labtech
7.13 Cell Biolabs, Inc.
7.14 Cell Signaling Technology, Inc. 
7.15 Charles River Laboratories 
7.16 Cisbio Bioassays
7.17 Corning, Inc.  
7.18 Cytek Biosciences
7.19 Cytovale
7.20 Enzo Biochem
7.21 Eurofins DiscoverX Corporation  
7.22 Evotec AG
7.23 Excellerate Bioscience
7.24 Fujifilm Cellular Dynamics International
7.25 Genedata
7.26 Hemogenix
7.27 Invivogen 
7.28 Leica Biosystems 
7.29 Lonza Group Ltd.  
7.30 Luminex Corp (DiaSorin)  
7.31 Merck & Co., Inc 
7.32 Miltenyi Biotec 
7.33 Molecular Devices
7.34 Nanion
7.35 Ncardia  
7.36 New England Biolabs, Inc. 
7.37 Novogene Bioinformatics Technology Co., Ltd.  
7.38 Olympus
7.39 Origene Technologies  
7.40 Perkin Elmer 
7.41 Promega
7.42 Qiagen 
7.43 Reaction Biology. 
7.44 Recursion Pharma
7.45 Roche Diagnostics
7.46 Sartorius  
7.47 Sartorius-ForteBio. 
7.48 Sartorius-IntelliCyt  
7.49 Singleron Biotechnologies 
7.50 Sony Biotechnology
7.51 SPT Labtech 
7.52 Stemcells Technologies Canada Inc.
7.53 Tecan
7.54 Thermo Fisher Scientific Inc.
7.55 Vitro Biopharma

8. Global Market Size 
8.1 Global Market Overview by Country 
8.1.1 Table -  Global Market by Country  
8.1.2 Chart -  Global Market by Country  
8.2 Global Market by User -  Overview  
8.2.1 Table -  Global Market by User  
8.2.2 Chart -  Global Market by User -  Base/End Year Comparison  
8.2.3 Chart -  Global Market by User -  Base Year  
8.2.4 Chart -  Global Market by User -  End Year 
8.2.5 Chart -  Global Market by User -  Share by Year  
8.3 Global Market by Product Class -  Overview  
8.3.1 Table -  Global Market by Product Class  
8.3.2 Chart -  Global Market by Product Class -  Base/End Year Comparison  
8.3.3 Chart -  Global Market by Product Class -  Base Year  
8.3.4 Chart -  Global Market by Product Class -  End Year  
8.3.5 Chart -  Global Market by Product Class -  Share by Year  

9. Global Market by User Type 
9.1 Pharma  
9.1.1 Table Pharma -  by Country  
9.1.2 Chart -  Pharma Growth  
9.2 Research  
9.2.1 Table Research -  by Country  
9.2.2 Chart -  Research Growth  
9.3 Industry/Cosmetic  
9.3.1 Table Industry/Cosmetic -  by Country  
9.3.2 Chart -  Industry/Cosmetic Growth  

10. Cell Based Assay by Product Class 
10.1 Instrument  
10.1.1 Table Instrument -  by Country  
10.1.2 Chart -  Instrument Growth  
10.2 Reagent  
10.2.1 Table Reagent -  by Country  
10.2.2 Chart -  Reagent Growth  
10.3 Services  
10.3.1 Table Services -  by Country  
10.3.2 Chart -  Services Growth  
10.4 Software  
10.4.1 Table Software -  by Country  
10.4.2 Chart -  Software Growth  

11. Appendices  
11.1 FDA Cancer Drug Approvals by Year  
11.2 Clinical Trials Started 2010 to 2016  
11.3 Share of Pharma R&D by Country  

List of Tables
Table 1: The Large Variety of Cell Lines  
Table 2: Some Common Viability Assays  
Table 3: Oxidative Stress Related Diseases  
Table 4: Important Signaling Pathways  
Table 5: Market Players by Type  
Table 6: Five Factors Driving Growth  
Table 7: Three Factors Limiting Growth  
Table 8: Global Market by Region  
Table 9: Global Market by User  
Table 10: Global Market by Product Class  
Table 11: Pharma by Country  
Table 12: Research by Country  
Table 13: Industry/Cosmetic by Country  
Table 14: Instrument by Country  
Table 15: Reagent by Country  
Table 16: Services by Country  
Table 17: Software by Country  

List of Figures
Figure 1: Reasons for Clinical Failure by Phase  
Figure 2: Immunotherapy Clinical Trial Growth  
Figure 3: Pharmaceutical Research Expenditures 2001 to 2017 ($Billion)  
Figure 4: Oxidative Stress and Free Radical Toxicity  
Figure 5: FDA Cancer Drug Approvals  
Figure 6: The Changing Approach to Cancer Diagnostics  
Figure 7: Growth rates of Cell Based Assays by Product Class  
Figure 8:  Global Market Share Chart  
Figure 9: Global Market by User -  Base vs. End Year  
Figure 10: Global Market by User Base Year  
Figure 11: Global Market by User End Year  
Figure 12 User Share by Year  
Figure 13: Global Market by Product Class -  Base vs. End Year  
Figure 14: Global Market by Product Class Base Year  
Figure 15: Global Market by Product Class End Year  
Figure 16: Product Class Share by Year 
Figure 17: Pharma Growth  
Figure 18: Research Growth  
Figure 19: Industry/Cosmetic Growth  
Figure 20: Instrument Growth  
Figure 21: Reagent Growth  
Figure 22: Services Growth  
Figure 23: Software Growth  
Figure 24: FDA Cancer Drug Approvals by Year  
Figure 25: Clinical Trials for Immunotherapy by Year  
Figure 26: Share of Pharma R&D by Country

Samples

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Companies Mentioned

  • Abcam  
  • Agilent
  • Aurora Instruments Ltd.  
  • Axxam  
  • Beckman Coulter Diagnostics  
  • Becton, Dickinson and Company  
  • Bio-Rad Laboratories, Inc.  
  • BioIVT  
  • BioTek Instruments  
  • BioVision, Inc.  
  •  BMG Labtech  
  • Cell Biolabs, Inc.  
  • Cell Signaling Technology, Inc.  
  • Charles River Laboratories  
  • Cisbio Bioassays  
  • Corning, Inc.  
  • Cytovale  
  • Enzo Life Sciences, Inc.  
  • Eurofins DiscoverX Corporation  
  • Evotec AG  
  • Excellerate Bioscience  
  • Fujifilm Cellular Dynamics International  
  • Genedata  
  • Hemogenix  
  • Horizon Discovery  
  • Invivogen  
  • Leica Biosystems  
  • Lonza Group Ltd.  
  • Luminex Corp  
  • Merck & Co., Inc  
  • Miltenyi Biotec  
  • Molecular Devices  
  • Nanion 
  • Ncardia  
  • New England Biolabs, Inc.  
  • Olympus  
  • Origene Technologies  
  • Perkin Elmer  Promega  
  • Qiagen Gmbh 
  • Reaction Biology 
  • Recursion Pharma  
  • Roche Diagnostics  
  • Sartorius  
  • Sartorius-ForteBio 
  • Sartorius-IntelliCyt  
  • Sony Biotechnology  
  • SPT Labtech  
  • Stemcells Technologies Canada Inc.  
  • Tecan  
  • Thermo Fisher Scientific Inc.  
  •  Vitro Biopharma  

Methodology

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