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Plant Bioactives as Natural Panacea against Age-Induced Diseases. Nutraceuticals and Functional Lead Compounds for Drug Development. Drug Discovery Update

  • Book
  • October 2022
  • Elsevier Science and Technology
  • ID: 5576583

Plant Bioactives as Natural Panacea Against Age-induced Diseases: Nutraceuticals and Functional Lead Compounds for Drug Development presents comprehensive information on the complications of aging and the bioactive phytochemicals that in specific herbal formulations, including beverages, can mitigate them. The book extensively describes the current information on the role of plant bioactive components in delaying or preventing the aging process and associated complications, while also covering different strategies and scientific evidence of possible synergistic effects of these studies, enabling the formulation of more effective natural drugs to intervene in aging and associated events.

Chapters cover the broad areas of plant bioactive compounds in promoting healthy aging and longevity, including balancing glucose homeostasis, in cognitive impairments, age-related diseases, food trends and the anti-aging diet in Asia and other regions, as well as the social and economic impact of dietary patterns in aging interventions. Written by a team of global experts.

Table of Contents

1. Aging principles and interventional perspectives (Invited article from renowned expert of gerontology) 2. Anti-aging strategies, plant bioactives and drug development: Current insights 3. Nutrigenomics, plant bioactives and healthy aging 4. Plant bioactives in balancing glucose homeostasis during aging and related diseases 5. Plant bioactives in immune modulation and its role in anti-aging 6. Plant bioactives, genes and longevity 7. Hormetic effects of plant bioactives on healthy aging and longevity 8. Anti-aging effect of polyphenols: possibilities and challenges 9. Plant polyphenols in balancing the redox state during aging 10. Mechanisms involved in prevention of dementia and promotion of healthy aging by resveratrol 11. An insight into plant polyphenols in prevention of brain aging 12. Plant polyphenols in regulation of ion channels during aging and induced diseases 13. Tea catechins as potent antioxidant and anti-inflammatory agents: possibilities of drug development to promote healthy aging 14. Functional foods, bioactives and cognitive impairments during aging 15. Functional foods in improving bone health during aging 16. Dietary restriction, vegetarian diet and aging intervention 17. Plant bioactives as promising therapeutic agents in Parkinson's disease targeting oxidative stress during aging 18. Novel plant bioactives, their anti-aging potencies: Reality and promises 19. Use of nanotechnology in refining the anti-aging activities of plant bioactives 20. Trends in plant based anti-aging diets in different continents of the world 21. Functional foods in clinical trials in aging intervention 22. Plant bioactives, aging research and drug industry: procedures and challenges


Kanti Bhooshan Pandey AcSIR; CSIR-Central Salt and Marine Chemicals Research Institute, Bhavnagar, India. Dr. Kanti Bhooshan Pandey is a Senior Scientist and Assistant Professor in the Faculty of Biological Sciences, AcSIR; CSIR-Central Salt and Marine Chemicals Research Institute, Gujarat, India. He is doctorate in Biochemistry. His research expertise includes clinical biochemistry, food biochemistry, molecular cell biology, and Gerontology. He has done significant work on investigation of molecular mechanisms of action of plant-derived polyphenols, a major constituent in food and vital in nutrition point of view. He is working to investigate human aging impairments at molecular level including cellular signaling. He has designed a new protocol in cell biology and investigated a novel mechanism of action of bioactive compounds involved in cellular homeostasis and ascorbate recycling. His findings have found commercial applications. Dr. Pandey is the recipient of many national and international fellowships and has been authored more than 57 research papers and book chapters. He is in the editorial/advisory board of many reputed international journals. Maitree Suttajit Maitree Suttajit, Phayao Province Thailand. Dr. Maitree Suttajit is Professor Emeritus previously at School of Medicine, Chiangmai University and later at School of Medical Sciences, University of Phayao, Thailand. He was Dean of this School between 2010-2015 and currently acts as a Research Advisor. He got his Ph.D from SUNY/Buffalo, USA in 1971. His active research has been on functional foods, and phytochemicals such as pigmented rice, perilla (Nga-mon), omega fatty acids, flavonoids, anthocyanidins, rosmarinic acid as well as antioxidants and anti-inflammation and antiaging activities. He has published more than 100 research papers and many book chapters with reputed international publishers. He was the Chairman organizing the first international conference on Innovation of Functional Foods in Asia (IFFA2018), Phayao, Thailand which was reported as "The innovation of functional foods in Asia: IFFA 2018", Asia Pacific J. Clin. Nutri. Sept.2019, 28(2):419-426. Dr. Maitree is in the editorial/review /coordinating/committee of many international journals.