Pediatric Anesthesia: A Guide for the Non-Pediatric Anesthesia is a comprehensive, contemporary reference that addresses all aspects of pediatric anesthesia. Both students and medical practitioners – novice and experienced - will find invaluable educational and practical information in this book. The book covers the subject in two parts.
Part I covers basic information about pediatric and neonatal anatomy and physiology, pharmacology, emergency room and operating room procedures and surgery. Chapters on general anesthetic procedures in emergency rooms, operational theatres and common surgeries.
Part II covers advanced topics for practicing healthcare professionals which include anesthesia for patients with a range of common and uncommon comorbidities, considerations for critically-ill patients, genetic disorders, pain management, COVID-19 guidelines for anesthesia, patient safety and research.
The text is an essential reference for scholars and professionals affiliated with general anesthesiology and surgery specialties at all levels who want to understand anesthesia for pediatric patients.
Part I covers basic information about pediatric and neonatal anatomy and physiology, pharmacology, emergency room and operating room procedures and surgery. Chapters on general anesthetic procedures in emergency rooms, operational theatres and common surgeries.
Part II covers advanced topics for practicing healthcare professionals which include anesthesia for patients with a range of common and uncommon comorbidities, considerations for critically-ill patients, genetic disorders, pain management, COVID-19 guidelines for anesthesia, patient safety and research.
Key features:
- Basic and advanced information about pediatric and neonatal anesthesia covered in 25 chapters over two parts
- Simple and organized presentation for learners
- Contributions by expert clinicians and researchers
- Special topics included such as considerations for patients with comorbidities and genetic disorders
- References for further reading
- Detailed illustrations and tables
The text is an essential reference for scholars and professionals affiliated with general anesthesiology and surgery specialties at all levels who want to understand anesthesia for pediatric patients.
Table of Contents
CHAPTER 1 STRUCTURE-BASED DRUG DISCOVERY APPROACHES APPLIED TO SARS-COV-2 (COVID-19)1. Homology Modeling
2. Pharmacophore Modeling
3. Molecular Docking and Dynamics Simulations
4. Fragment-Based Drug Discovery
5. De Novo Drug Discovery
5. Virtual Screening (VS) and Virtual High-throughput screening (vHTS)
- CHALLENGES IN SBDD FOR SARS-COV-2
- CONCLUSION
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGMENTS
- REFERENCES
1. Lemon balm (Melissa Officinalis L.)
2. Rosemary (Rosmarinus Officinalis L.)
3. Olive leaf (Olea Europea L.)
4. Thyme Species (Origanum, Thymus & Thymbra)
5. Licorice Root (Glycyrrhiza Glabra L.)
6. Other Antiviral Medicinal Plants
- CONCLUSION AND FUTURE DIRECTIONS
- LIST OF ABBREVIATIONS
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
MAIN TARGETS OF SARS-COV AND SARS-COV-2
1. Glycoprotein Spike (S)
2. Membrane Protein (M)
3. Envelope Protein (E)
4. Nucleocapsid Protein (N)
5. 3-chymotrypsin-like Cysteine Protease (3CLpro)
6. Angiotensin-Converting Enzyme (ACE)-2
- DRUGS AND INHIBITORS AGAINST SARS
- CONCLUSION
- LIST OF ABBREVIATIONS
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
CHAPTER 4 NATURAL SOURCED TRADITIONAL INDIAN AND CHINESE MEDICINES TO COMBAT COVID-19
1. INTRODUCTION TO INDIAN AND CHINESE TRADITIONAL MEDICINETRADITIONAL DRUGS AND NATURAL SOURCED FORMULATION FOR TREATMENT OF COVID-19
2. Traditional Indian Medicines (TIM) to Combat COVID-19
3. Traditional Chinese Medicine (TCM) To Combat COVID-19
- CONCLUSION
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
1. Structure, Function, and Druggability of 3CLpro from Coronaviruses
2. Catalytic Site of 3CLpro from Coronaviruses
CORONAVIRUSES 3CLPRO AND THEIR INHIBITORS
1. Warhead Groups
2. Peptidomimetics Containing Michael Acceptors as Warhead Groups
3. Peptidomimetics Containing Aldehydes as Warhead Groups
4. Peptidomimetics Containing Keto Groups as Warheads
4.1. Fluoromethyl Ketone Group
4.2. 1,4-Peptidomimetics Containing Phthalazinediones as Warhead Groups
4.3. Peptidomimetics Containing Benzothiazolones/thiazolones as Warhead Groups 175 4.4.4. Peptidomimetics Containing α-ketoamides as Warhead Groups
4.5. Peptidomimetics Containing Nitroanilides as Warhead Groups
5. Peptidomimetics Containing Nitriles as Warhead Groups
6. Peptidomimetics Containing Aza-epoxides and Aziridines as Warhead Groups
- DRUG REPURPOSING FOR PEPTIDOMIMETICS
- FINAL CONSIDERATIONS AND FUTURE OUTLOOK
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- SUBJECT INDEX
Author
- Bharathi GourkantI
- Irwin Gratz
- Grace Dippo
