MR Linac Radiotherapy. A New Personalized Treatment Approach. Advances in Magnetic Resonance Technology and Applications Volume 8

Table of Contents

1. History of development of MR-Linac
2. Basics of MR imaging for radiation oncologist -
3. MR safety for MR guided RT
4. Technical concept of current clinical MR-Linacs
5. Immobilization systems in MR guided RT
6. Use of MR-Linac as a simulator for radiotherapy department
7. Simulation workflow in MR guided RT
8. Patient reported outcomes in MR guided RT
9. Contrast use in MR guided RT
10. Treatment workflow steps in MR guided adaptive RT
11. Changing role of RTTs in MR guided RT
12. Role of MR-linac in management of brain tumors and brain metastasis
13. The role of adaptive RT in head and neck cancers and future perspective for MR guided RT
14. Use of MR-linac in peripheral and central lung tumors and metastasis
15. Current role and future perspectives in breast cancer treatment with MR-linac
16. Role of MR guided RT in management of liver tumors and metastases
17. Dose escalation in SBRT of pancreatic cancer using adaptive online RT
18. Hypofractionation and MR guided RT in management of prostate cancers
19. Use of MR-linac in management of locally recurrent prostate cancer
20. Potential role of Mr guided RT in pediatric cancers
21. Role of MR-linac in management of bone or lymph node oligometastasis
22. Future clinical use of MR-Linac.
22. Use of AI in MR-linac workflow
23. Role of radiomics in MR guided RT

Authors

Sara L. Hackett University Medical Center, Utrecht, The Randstad, The Netherlands. Sara Hackett completed her B.Sc. (Hons) in Physics and Mathematics at the University of Western Australia in 2003, was awarded a Ph.D. with Distinction in 2008 by the same institute. She trained as a Medical Physicist, specializing in Radiotherapy, and received her certification in 2010. During this period she also completed an M.Sc. in Medical Physics with the Royal Melbourne Institute of Technology. After working as a postdoctoral fellow at the Universit� catholique de Louvain and the University of Oxford, she joined the Experimental Medical Physics group at University Medical Center Utrecht (UMCU) as a postdoctoral physis fellow to work on the clinical introduction of the MR-linac.

Dr. Hackett now works as a clinical physicist at UMCU with the primary responsibility for treatment planning. The Radiotherapy department has three MR-linacs, as well as ten Agility linacs. She is involved with lung radiotherapy on the MR-linac and is supervising M.Sc. and Ph.D. students in the development of gating, tracking and real-time-adapted radiotherapy. Cem Onal Baskent University Faculty of Medicine, Department of Radiation Oncology, Ankara, Turkey. Prof. Cem Onal is the founder and Chair of the Radiation Oncology Department at Baskent University. Prof. Onal completed his residency in radiation oncology in 2004 at Hacettepe University School of Medicine in Ankara. His primary research interests are prostate cancer, breast cancer, and gynecological malignancies. He has extensive experience using intensity modulated radiotherapy and image guided radiotherapy to treat prostate cancer, as well as brachytherapy for gynecological tumors, stereotactic radiotherapy, and radiosurgery. He is the director of the MR-Linac unit and has extensive experience treating prostate cancer and abdominal tumors with MR-Linac. He is also skilled in computed tomography-guided brachytherapy, intensity modulated radiotherapy, image-guided radiotherapy, stereotactic body radiotherapy/radiosurgery, and helical tomotherapy.
He has over 150 articles published in international and national journals. He has also presented over 350 international and national abstracts at various scientific meetings. He serves as the editorial board member and peer reviewer in several journals. Enis Ozyar Department of Radiation Oncology, Acibadem MAA University, Istanbul, Turkey. Enis Ozyar M.D., graduated from Ankara University, Medical School, Ankara, Turkey in 1985 and finished his residency at Hacettepe University, School of Medicine, Department of Radiation Oncology, Ankara in 1993. He worked at the same department between 1993-2008. He obtained his associate professorship degree in 1998 and professorship degree in 2003. He was appointed as Chair and Professor of Radiation Oncology at the Acibadem MAA University, School of Medicine, Department of Radiation Oncology, Istanbul, Turkey in 2008.

Dr. Ozyar currently works at flaghship hospital - Acibadem Maslak Hospital - of the Acibadem Health Group (AHG). AHG is the largest private health care group in Turkey and have 8 Radiation Oncology centers equipped with high tech systems such as MRIdien Mr-Linac, IGRT-IMRT-SRT linac systems, robotic linacs, Gammaknife, brachytherapy and intraoperative radiotherapy. Dr. Ozyar is also working as coordinator of Radiation Oncology Centers of AHG. He is also charing Acibadem RTT school and Health Physics programme of Acibadem MAA University.

His main interest areas are head and neck cancer, prostate cancer, gynecological cancers, sterotactic radiotherapy and MR guided radiotherapy.

Dr. Ozyar published more than 100 manuscripts published in international SCI journals. His h-index is 27.