Smallpox Vaccine is the fastest growing segment, North America is the largest regional market
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Key Market Drivers
The increasing global incidence of monkeypox outbreaks profoundly influences the therapeutics market by creating an urgent and sustained demand for effective treatments and preventative measures. Each new surge in cases directly translates into a heightened need for antiviral drugs and vaccines to manage symptoms, prevent severe disease, and curb transmission.According to the Pan American Health Organization/WHO, in October 2024, an Epidemiological Update reported 109,699 confirmed cases of mpox globally between January 2022 and September 30, 2024, further indicating a monthly increase of 8% in new cases in September 2024 compared to August, underscoring the ongoing spread of the virus and the persistent threat it poses to public health. This rising incidence drives pharmaceutical companies to allocate resources towards research and development, aiming to innovate and expand their portfolio of monkeypox therapeutics.
Key Market Challenges
The limited availability of specifically approved therapeutic agents for monkeypox presents a substantial challenge to the growth of the Global Monkeypox Therapeutics Market. Current treatment protocols frequently depend on drugs originally developed for smallpox, which may not consistently prove optimal or widely accessible for monkeypox virus infections. This reliance creates a significant barrier to the rapid and widespread deployment of tailored interventions, particularly when considering evolving viral clades and diverse geographical spread.Key Market Trends
The global monkeypox therapeutics market is experiencing significant evolution, driven by shifts in drug development and preventative strategies. One prominent trend is the **Evolution Towards Oral Antiviral Therapeutic Options**. This movement is crucial for improving patient access, adherence, and facilitating outpatient care, thereby easing the burden on healthcare infrastructure.Oral formulations offer a more convenient alternative to intravenous treatments, which can be critical during outbreaks. For example, NanoViricides, Inc. announced in July 2025 the near-finalization of its adaptive Phase II clinical trial protocol for NV-387, a novel oral antiviral designed to treat monkeypox virus infections, highlighting the ongoing efforts to develop user-friendly treatment options. This aligns with a broader pharmaceutical industry trend where oral drug development remains a priority due to its patient-centric benefits.
Key Market Players Profiled:
- Chimerix Inc.
- SIGA Technologies, Inc.
- Emergent BioSolutions Inc.
- Bavarian Nordic A/S
- Hetero Drugs Limited
- Mylan N.V.
- Piramal Enterprises Limited
- Olon S.p.A.
- Teva Pharmaceutical Industries Limited
- CIDIC Company Limited
Report Scope:
In this report, the Global Monkeypox Therapeutics Market has been segmented into the following categories:By Treatment:
- Smallpox Vaccine
- Antivirals
- Vaccinia Immune Globulin (VIG)
By End User:
- Hospitals
- Specialty Clinics
- Ambulatory Surgical Centers
- Others
By Region:
- North America
- Europe
- Asia-Pacific
- South America
- Middle East & Africa
Competitive Landscape
Company Profiles: Detailed analysis of the major companies present in the Global Monkeypox Therapeutics Market.Available Customizations:
With the given market data, the publisher offers customizations according to a company's specific needs. The following customization options are available for the report.Company Information
- Detailed analysis and profiling of additional market players (up to five).
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Table of Contents
Companies Mentioned
The companies profiled in this Monkeypox Therapeutics market report include:- Chimerix Inc.
- SIGA Technologies, Inc.
- Emergent BioSolutions Inc.
- Bavarian Nordic A/S
- Hetero Drugs Limited
- Mylan N.V.
- Piramal Enterprises Limited
- Olon S.p.A.
- Teva Pharmaceutical Industries Limited
- CIDIC Company Limited
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 185 |
| Published | November 2025 |
| Forecast Period | 2024 - 2030 |
| Estimated Market Value ( USD | $ 87 Million |
| Forecasted Market Value ( USD | $ 145.99 Million |
| Compound Annual Growth Rate | 9.0% |
| Regions Covered | Global |
| No. of Companies Mentioned | 11 |


