G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes.
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Table of Contents
Preface Arun K. Shukla 1. Computational and experimental approaches to probe GPCR activation and signaling Paulina Dragan, Alessandro Atzei, Swapnil Ganesh Sanmukh and Dorota Latek 2. Adrenergic receptors in breast cancer Cecilia P�rez Pi�ero, Ezequiel Mariano Rivero, Luc�a Gargiulo, Mar�a Sol Rodr�guez, Carlos David Bruque, Ariana Bruzzone and Isabel Alicia L�thy 3. Tools for adapting to a complex habitat: G-protein coupled receptors in Trichoderma Monika Schmoll and Wolfgang Hinterdobler 4. Targeting G protein-coupled receptors for alleviating neuropathic pain Poonam Kumari, Anubhav Yadav, Monika Patel and Prem N. Yadav 5. Crosstalk between neurons and glia through G-protein coupled receptors: Insights from Caenorhabditis elegans Pratima Pandey, Gazaldeep Kaur and Kavita Babu 6. Cardiovascular GPCR regulation by regulator of G protein signaling proteins Anastasios Lymperopoulos, Malka S. Suster and Jordana I. Borges 7. The interaction, mechanism and function of GPR158-RGS7 cross-talk Shradha Darira and Laurie P. Sutton 8. Taste GPCRs and their ligands Nitzan Dubovski, Fabrizio Fierro, Eitan Margulis, Yaron Ben Shoshan-Galeczki, Lior Peri and Masha Y. Niv 9. Palmitoylation and G-protein coupled receptors Georges Chaloub and Peter J. McCormick
