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Tezepelumab Emerging Drug Insight and Market Forecast - 2032

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    Drug Pipelines

  • 30 Pages
  • September 2022
  • Region: Global
  • DelveInsight
  • ID: 5648661
“Tezepelumab Emerging Drug Insight and Market Forecast - 2032” report provides comprehensive insights about Tezepelumab for Nasal Polyposis in the 7MM. A detailed picture of the Tezepelumab for Nasal Polyposis in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan, for the study period 2019-2032 is provided in this report along with a detailed description of the Tezepelumab for Nasal Polyposis . The report provides insight about mechanism of action, dosage and administration, as well as research and development activity including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the Tezepelumab market forecast, analysis for Nasal Polyposis in the 7MM, descriptive analysis such as SWOT, analyst views, comprehensive overview of market competitors, and brief about other emerging therapies in Nasal Polyposis.

Drug Summary

AstraZeneca is developing Tezepelumab as a potential human monoclonal antibody that inhibits the action of Thymic Stromal Lymphopoietin (TSLP). TSLP is an epithelial-derived cytokine produced in response to airborne stimuli such as allergens, viruses, and diesel exhaust. It plays a key role in the initiation and persistence of airway inflammation by activating multiple downstream inflammatory pathways. TSLP expression is elevated in the airways of patients with asthma compared with healthy individuals and in nasal polyp tissue from patients with CRSwNP compared with healthy sinus tissue or that from patients with CRS without Nasal Polyposis. The presence of TSLP correlates with the number of eosinophils in nasal polyp tissue, and the activity of TSLP in polyp tissue is believed to be sufficient to trigger an inflammatory response. In patients with asthma, the level of TSLP expression in airway tissue has been shown to correlate with airway obstruction and disease severity. Tezepelumab is a human monoclonal antibody (immunoglobulin [Ig] G2λ) that binds specifically to TSLP, preventing its interaction with its heterodimeric receptor.

Tezepelumab is in a Phase III clinical trial for nasal polyps and other indications. The positive response for CRSwNP Tezepelumab was investigated in clinical trials, specifically Pathway and Navigator, which were designed for the Asthma indication.

Scope of the Report

The report provides insights into:

  • A comprehensive product overview including the Tezepelumab description, mechanism of action, dosage and administration, research and development activities in Nasal Polyposis.
  • Elaborated details on Tezepelumab regulatory milestones and other development activities have been provided in this report.
  • The report also highlights the Tezepelumab research and development activity in Nasal Polyposis details across the United States, Europe and Japan.
  • The report also covers the patents information with expiry timeline around Tezepelumab.
  • The report contains forecasted sales of Tezepelumab for Nasal Polyposis till 2032.
  • Comprehensive coverage of the late-stage emerging therapies for Nasal Polyposis.
  • The report also features the SWOT analysis with analyst views for Tezepelumab in Nasal Polyposis.

Methodology

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by the research team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

Tezepelumab Analytical Perspective

In-depth Tezepelumab Market Assessment

This report provides a detailed market assessment of Tezepelumab in Nasal Polyposis in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan. This segment of the report provides forecasted sales data from 2023 to 2032.

Tezepelumab Clinical Assessment

The report provides the clinical trials information of Tezepelumab in Nasal Polyposis covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights

  • In the coming years, the market scenario for Nasal Polyposis is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
  • The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence Tezepelumab dominance.
  • Other emerging products for Nasal Polyposis are expected to give tough market competition to Tezepelumab and launch of late-stage emerging therapies in the near future will significantly impact the market.
  • A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of Tezepelumab in Nasal Polyposis.
  • This in-depth analysis of the forecasted sales data of Tezepelumab from 2023 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the Tezepelumab in Nasal Polyposis.

Key Questions

  • What is the product type, route of administration and mechanism of action of Tezepelumab?
  • What is the clinical trial status of the study related to Tezepelumab in Nasal Polyposis and study completion date?
  • What are the key collaborations, mergers and acquisitions, licensing and other activities related to the Tezepelumab development?
  • What are the key designations that have been granted to Tezepelumab for Nasal Polyposis?
  • What is the forecasted market scenario of Tezepelumab for Nasal Polyposis?
  • What are the forecasted sales of Tezepelumab in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
  • What are the other emerging products available in Nasal Polyposis and how are they giving competition to Tezepelumab for Nasal Polyposis?
  • Which are the late-stage emerging therapies under development for the treatment of Nasal Polyposis?


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Table of Contents

1. Report Introduction
2. Tezepelumab Overview in Nasal Polyposis
2.1. Product Detail
2.2. Clinical Development
2.2.1. Clinical Studies
2.2.2. Clinical Trials Information
2.2.3. Safety and Efficacy
2.3. Other Development Activities
2.4. Product Profile
3. Competitive Landscape (Marketed Therapies)4. Competitive Landscape (Late-stage Emerging Therapies)*
5. Tezepelumab Market Assessment
5.1. Market Outlook of Tezepelumab in Nasal Polyposis
5.2. 7MM Market Analysis
5.2.1. Market Size of Tezepelumab in the 7MM for Nasal Polyposis
5.3. Country-wise Market Analysis
5.3.1. Market Size of Tezepelumab in the United States for Nasal Polyposis
5.3.2. Market Size of Tezepelumab in Germany for Nasal Polyposis
5.3.3. Market Size of Tezepelumab in France for Nasal Polyposis
5.3.4. Market Size of Tezepelumab in Italy for Nasal Polyposis
5.3.5. Market Size of Tezepelumab in Spain for Nasal Polyposis
5.3.6. Market Size of Tezepelumab in the United Kingdom for Nasal Polyposis
5.3.7. Market Size of Tezepelumab in Japan for Nasal Polyposis
6. SWOT Analysis7. Analysts’ Views
8. Appendix
8.1. Bibliography
8.2. Report Methodology
9. Publisher Capabilities10. Disclaimer11. About the Publisher12. Report Purchase Options
List of Tables
Table 1: Tezepelumab, Clinical Trial Description, 2022
Table 2: Tezepelumab : General Description
Table 3: Competitive Landscape (Marketed Therapies)
Table 4: Competitive Landscape (Late - stage Emerging Therapies)
Table 5: Tezepelumab Market Size in the 7MM, in USD million (2019-2032)
Table 6: Tezepelumab Market Size in the US, in USD million (2019-2032)
Table 7: Tezepelumab Market Size in Germany, in USD million (2019-2032)
Table 8: Tezepelumab Market Size in France, in USD million (2019-2032)
Table 9: Tezepelumab Market Size in Italy, in USD million (2019-2032)
Table 10: Tezepelumab Market Size in Spain, in USD million (2019-2032)
Table 11: Tezepelumab Market Size in the UK, in USD million (2019-2032)
Table 12: Tezepelumab Market Size in Japan, in USD million (2019-2032)
List of Figures
Figure 1: Market Size of Tezepelumab in the 7MM, in USD million (2019-2032)
Figure 2: Market Size of Tezepelumab in the United States, in USD million (2019-2032)
Figure 3: Market Size of Tezepelumab in Germany, in USD million (2019-2032)
Figure 4: Market Size of Tezepelumab in France, in USD million (2019-2032)
Figure 5: Market Size of Tezepelumab in Italy, in USD million (2019-2032)
Figure 6: Market Size of Tezepelumab in Spain, in USD million (2019-2032)
Figure 7: Market Size of Tezepelumab in United Kingdom, in USD million (2019-2032)
Figure 8: Market Size of Tezepelumab in Japan, in USD million (2019-2032)