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Synthetic Small Molecule API Market Size, Share & Trends Analysis Report by Manufacturer (In-house, Outsourced), by Application (Cardiology, Oncology), by Region, and Segment Forecasts, 2022-2030

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    Report

  • 90 Pages
  • September 2022
  • Region: Global
  • Grand View Research
  • ID: 5665117
The global synthetic small molecule API market size is expected to reach USD 217.17 billion by 2030. The market is expected to register a CAGR of 5.73% from 2022 to 2030. This can be attributed to the increasing demand for pharmaceuticals and new small molecule-based drugs globally. Moreover, small molecules API offers versatility between dosage forms and has an easier means of purification, which makes it more acceptable and increases the demand.

There is an increasing dominance of synthetic drugs in the pharmaceutical industry, which is expected to propel the requirement of raw materials such as small molecule APIs for production. Moreover, technological advancements related to the enhancement of existing products are expected to provide new opportunities for small molecule therapeutics. For instance, in March 2022, Evonik launched the new EUDRATECSoluFlow technology that enhances the solubility of oral small molecules.

The market is driven by positive government support for the production of APIs in various regions, particularly in Asia, where the majority of API manufacturers are dependent on the supply of API for the production of synthetic small molecule APIs. There has been an increasing focus on outsourcing activities for API production. For instance, in April 2020, for managing COVID-19, Wavelength Pharmaceuticals expanded the supply of key drug ingredients for certain pharmaceutical products needed to manage respiratory critical care patients and launched API CDMO services. Emerging markets such as China, India, and Southeast Asia represent significant opportunities for growth.

The investment in new and complex technologies is relatively low for Asian manufacturers as they are more focused on less complex molecules that can be produced in bulk. Thus, the investment in high-yielding, low-cost technologies is an alternative for manufacturers in other developed regions such as Europe and North America to avoid competitive pressure.

Key players operating in the market are focusing on collaboration for the production of potent API products. For instance, in August 2021, Almac Sciences signed an agreement with Pila Pharma for the production of the API XEN-D0501, a highly potent and selective small molecule TRPV1 antagonist. Moreover, CDMOs are constantly evolving by expanding their capacities to meet the heightened demand for synthetic drugs. For instance, in April 2022, AGC Inc. announced the expansion of its Spanish facility by 7500 m2 for synthetic pharmaceutical production, which is expected to enhance the demand for synthetic small molecule active pharmaceutical ingredients in the region.

Synthetic Small Molecule API Market Report Highlights

  • The growth of the overall market is attributed to the increasing production of pharmaceuticals with the increased demand for raw material
  • The API market is witnessing a key shift with the rise in the preference for CDMOs for the production of synthetic small molecule active pharmaceutical ingredients in bulk
  • By manufacturer, the outsourced segment is expected to witness lucrative growth over the forecast period owing to a dependency of small and mid-sized companies on outsourcing for commercial production
  • The cardiology appolication segment dominated the market in 2021. This is attributed to the increasing prevalence of target diseases
  • North America dominated the market in 2021 due to the presence of key players and rising support from the government for enhancing the API manufacturing capacity of the region


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Table of Contents

Chapter 1 Synthetic Small Molecule API Market: Methodology And Scope
1.1 Market Segmentation
1.1.1 Segment Scope
1.1.2 Regional Scope
1.1.3 Estimates And Forecast Timeline
1.2 Research Methodology
1.3 Information Procurement
1.3.1 Purchased Database
1.3.2 Internal database
1.3.3 Secondary Sources
1.3.4 Primary Research
1.3.5 Details Of Primary Research
1.4 Information Or Data Analysis
1.4.1 Data Analysis Models
1.5 Market Formulation & Validation
1.6 Model Details
1.6.1 Commodity Flow Analysis
1.6.1.1 Approach 1: Commodity Flow Approach
1.6.1.2 Approach 2: Country Wise Market Estimation Using Bottom Up Approach
1.6.1.3 Approach 2: Country Wise Market Estimation Using Top Down Approach
1.7 Global Market: CAGR Calculation
1.8 Regional Market: CAGR Calculation
1.9 List Of Secondary Sources
1.10 Objectives
1.10.1 Objective 1:
1.10.2 Objective 2:
1.11 List of Abbreviations
Chapter 2 Synthetic Small Molecule API Market: Executive Summary
2.1 Synthetic Small Molecule API Market: Market Outlook
2.1.1 Market Summary
Chapter 3 Synthetic Small Molecule API Market: Industry Outlook
3.1 Market Lineage Outlook
3.1.1 Parent Market Lineage Outlook
3.1.2 Related/Ancillary Market Outlook
3.2 Penetration & Growth Prospect Mapping
3.3 Market Dynamics
3.3.1 Market Drivers
3.3.1.1 High growth of the pharmaceutical industry
3.3.1.2 Rising R&D and launch of novel molecules
3.3.1.3 Increased outsourcing of API production
3.3.1.4 Growing geriatric population
3.3.1.5 Escalating prevalence of chronic diseases
3.3.2 Market restraint Analysis
3.3.2.1 Emergence of biologics
3.3.2.2 High dependence on Asian nations for production
3.4 SWOT Analysis, By Factor (Political & Legal, Economic and Technological)
3.5 Industry Analysis - Porter’s
3.6 Reimbursement & Regulatory Scenario
3.7 Major Deals & Strategic Alliances
3.7.1 New Product Launch
3.7.2 Acquisition
3.7.3 Expansion
3.7.4 Partnerships
3.7.5 Marketing & Promotions
Chapter 4 Synthetic Small Molecule API Market: Competitive Landscape
4.1 Recent developments & impact analysis, by key market participants
4.1.1 Ansoff Matrix
4.2 Company Categorization
4.2.1 Innovators
4.2.1.1 Market Differentiators
4.3 Vendor Landscape
4.3.1 List Of Key Distributors And Channel Partners
4.3.2 Key Customers
4.3.3 Key Company Market Share Analysis, 2021
4.4 Public Companies
4.4.1 Competitive Dashboard Analysis
4.5 Private Companies
4.5.1 List Of Key Emerging Companies
4.6 Regional Network Map
Chapter 5 Synthetic Small Molecule API Market: Manufacturer Business Analysis
5.1 Synthetic Small Molecule API Market: Manufacturer Movement Analysis
5.2 In-house
5.2.1 Market estimates and forecast, 2018 - 2030 (USD Billion) (Volume, in Metric Tons)
5.3 Outsourced
5.3.1 Market estimates and forecast, 2018 - 2030 (USD Billion)(Volume, in Metric Tons)
Chapter 6 Synthetic Small Molecule API Market: Application Business Analysis
6.1 Synthetic Small Molecule API Market: Application Movement Analysis
6.2 Cardiology
6.2.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
6.3 Oncology
6.3.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
6.4 CNS and Neurology
6.4.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
6.5 Orthopedic
6.5.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
6.6 Endocrinology
6.6.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
6.7 Pulmonology
6.7.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
6.8 Gastroenterology
6.8.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
6.9 Nephrology
6.9.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
6.10 Opthalmology
6.10.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
6.11 Others
6.11.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
Chapter 7 Synthetic Small Molecule API Market: Regional Business Analysis
7.1 Market Share Analysis by Country, 2021 & 2030
7.1.1 North America
7.1.1.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.1.2 U.S.
7.1.1.2.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.1.3 Canada
7.1.1.3.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.2 Europe
7.1.2.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.2.2 U.K.
7.1.2.2.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.2.3 Germany
7.1.2.3.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.2.4 France
7.1.2.4.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.2.5 Italy
7.1.2.5.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.2.6 Spain
7.1.2.6.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.3 Asia Pacific
7.1.3.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.3.2 Japan
7.1.3.2.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.3.3 China
7.1.3.3.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.3.4 India
7.1.3.4.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.3.5 South Korea
7.1.3.5.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.3.6 Australia
7.1.3.6.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.4 Latin America
7.1.4.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.4.2 Brazil
7.1.4.2.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.4.3 Mexico
7.1.4.3.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.4.4 Argentina
7.1.4.4.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.5 Middle East & Africa
7.1.5.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.5.2 South Africa
7.1.5.2.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.5.3 Saudi Arabia
7.1.5.3.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
7.1.5.4 UAE
7.1.5.4.1 Market estimates and forecast, 2018 - 2030 (USD Billion)
Chapter 8 Synthetic Small Molecule API Market: Company Profiling
8.1 Company Profiles
8.1.1 AbbVie, Inc.
8.1.1.1 Company overview
8.1.1.2 Financial performance
8.1.1.3 Product benchmarking
8.1.1.4 Strategic initiatives
8.1.2 Bristol-Myers Squibb Company
8.1.2.1 Company overview
8.1.2.2 Financial performance
8.1.2.3 Product benchmarking
8.1.2.4 Strategic initiatives
8.1.3 Boehringer Ingelheim International GmbH
8.1.3.1 Company overview
8.1.3.2 Financial performance
8.1.3.3 Product benchmarking
8.1.3.4 Strategic initiatives
8.1.4 Cipla Inc.
8.1.4.1 Company overview
8.1.4.2 Financial performance
8.1.4.3 Product benchmarking
8.1.4.4 Strategic initiatives
8.1.5 Teva Pharmaceutical Industries Ltd.
8.1.5.1 Company overview
8.1.5.2 Financial performance
8.1.5.3 Product benchmarking
8.1.5.4 Strategic initiatives
8.1.6 Albemarle Corporation
8.1.6.1 Company overview
8.1.6.2 Financial performance
8.1.6.3 Product benchmarking
8.1.6.4 Strategic initiatives
8.1.7 Viatris Inc.
8.1.7.1 Company overview
8.1.7.2 Financial performance
8.1.7.3 Product benchmarking
8.1.7.4 Strategic initiatives
8.1.8 Aurobindo Pharma
8.1.8.1 Company overview
8.1.8.2 Financial performance
8.1.8.3 Product benchmarking
8.1.8.4 Strategic initiatives
8.1.9 Sun Pharmaceutical Industries Ltd.
8.1.9.1 Company overview
8.1.9.2 Financial performance
8.1.9.3 Product benchmarking
8.1.9.4 Strategic initiatives
8.1.10 Dr. Reddy’s Laboratories Ltd.
8.1.10.1 Company overview
8.1.10.2 Financial performance
8.1.10.3 Product benchmarking
8.1.10.4 Strategic initiatives
8.2 List of Other Key Players
List of Tables
Table 1 List of Secondary Sources
Table 2 List of Abbreviations
Table 3 Incidence of Diseases
Table 4 Global Synthetic Small Molecule API Market, By Region, 2018 - 2030 (USD Billion)
Table 5 Global Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 6 Global Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 7 North America Synthetic Small Molecule API Market, By Country, 2018 - 2030 (USD Billion)
Table 8 North America Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 9 North America Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 10 U.S. Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 11 U.S. Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 12 Canada Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 13 Canada Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 14 Europe Synthetic Small Molecule API Market, By Country, 2018 - 2030 (USD Billion)
Table 15 Europe Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 16 Europe Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 17 Germany Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 18 Germany Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 19 U.K. Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 20 U.K. Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 21 France Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 22 France Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 23 Italy Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 24 Italy Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 25 Spain Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 26 Spain Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 27 Asia Pacific Synthetic Small Molecule API Market, By Country, 2018 - 2030 (USD Billion)
Table 28 Asia Pacific Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 29 Asia pacific Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 30 Japan Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 31 Japan Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 32 China Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 33 China Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 34 India Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 35 India Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 36 South Korea Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 37 South Korea Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 38 Australia Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 39 Australia Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 40 Latin America Synthetic Small Molecule API Market, By Country, 2018 - 2030 (USD Billion)
Table 41 Latin America Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 42 Latin America Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 43 Brazil Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 44 Brazil Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 45 Mexico Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 46 Mexico Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 47 Argentina Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 48 Argentina Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 49 Middle East & Africa Synthetic Small Molecule API Market, By Country, 2018 - 2030 (USD Billion)
Table 50 Middle East & Africa Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 51 Middle East & Africa Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 52 Saudi Arabia Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 53 Saudi Arabia Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 54 South Africa Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 55 South Africa Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
Table 56 UAE Synthetic Small Molecule API Market, By Manufacturer, 2018 - 2030 (USD Billion)
Table 57 UAE Synthetic Small Molecule API Market, By Application, 2018 - 2030 (USD Billion)
List of Figures
Fig. 1 Synthetic small molecule API market segmentation
Fig. 2 Market research process
Fig. 3 Data triangulation techniques
Fig. 4 Primary research pattern
Fig. 5 Market research approaches
Fig. 6 Value-chain-based sizing & forecasting
Fig. 7 QFD modeling for market share assessment
Fig. 8 Market formulation & validation
Fig. 9 Synthetic Small Molecule API market snapshot
Fig. 10 Parent market outlook
Fig. 11 Related/ancillary market outlook, revenue, 2021, (USD Billion)
Fig. 12 Penetration and growth prospect mapping
Fig. 13 Synthetic small molecule API market driver impact
Fig. 14 Synthetic small molecule API market restraint impact
Fig. 15 SWOT analysis, by factor (political & legal, economic, and technological)
Fig. 16 Industry Analysis - Porter’s
Fig. 17 Strategy mapping
Fig. 18 Synthetic small molecule API market: manufacturer outlook and key takeaways
Fig. 19 Synthetic small molecule API market: manufacturer movement analysis & market share 2021 & 2030
Fig. 20 In-house market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 21 Outsourced market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 22 Synthetic small molecule API market: application outlook and key takeaways
Fig. 23 Synthetic small molecule API market: application movement analysis & market share 2021 & 2030
Fig. 24 Cardiology market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 25 Oncology market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 26 CNS and Neurology market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 27 Orthopedic market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 28 Endocrinology market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 29 Pulmonology market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 30 Gastroenterology market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 31 Nephrology market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 32 Ophthalmology market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 33 Others market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 34 Small Molecule API: Regional outlook and key takeaways
Fig. 35 Regional outlook, 2021 & 2030
Fig. 36 North America
Fig. 37 North America market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 38 U.S.
Fig. 39 U.S. market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 40 Canada
Fig. 41 Canada market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 42 Europe
Fig. 43 Europe market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 44 U.K.
Fig. 45 U.K. market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 46 Germany
Fig. 47 Germany market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 48 France
Fig. 49 France market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 50 Italy
Fig. 51 Italy market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 52 Spain
Fig. 53 Spain market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 54 Asia Pacific
Fig. 55 Asia Pacific market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 56 Japan
Fig. 57 Japan market estimates and forecast, 2018 - 2030(USD Billion)
Fig. 58 China
Fig. 59 China market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 60 India
Fig. 61 India market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 62 South Korea
Fig. 63 South Korea market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 64 Australia
Fig. 65 Australia market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 66 Latin America
Fig. 67 Latin America market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 68 Brazil
Fig. 69 Brazil market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 70 Mexico
Fig. 71 Mexico market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 72 Argentina
Fig. 73 Argentina market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 74 Middle East & Africa
Fig. 75 MEA market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 76 South Africa
Fig. 77 South Africa market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 78 Saudi Arabia
Fig. 79 Saudi Arabia market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 80 UAE
Fig. 81 UAE market estimates and forecast, 2018 - 2030 (USD Billion)
Fig. 82 Ansoff Matrix
Fig. 83 Market differentiators
Fig. 84 Key company market share analysis, 2021
Fig. 85 Company market position analysis
Fig. 86 Competitive dashboard analysis
Fig. 87 Regional network map

Companies Mentioned

  • Abbvie, Inc.
  • Bristol-Myers Squibb Company
  • Boehringer Ingelheim International GmbH
  • Cipla Inc.
  • Teva Pharmaceutical Industries Ltd.
  • Albemarle Corporation
  • Viatris Inc.
  • Aurobindo Pharma
  • Sun Pharmaceutical Industries Ltd.
  • Dr. Reddy’S Laboratories Ltd.

Methodology

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