The global scaffold technology market was valued at $1,026.0 million in 2021, and is projected to reach $5,095.3 million by 2031, registering a CAGR of 18.0% from 2022 to 2031.
Tissue engineering covers a wide range of applications that repair or replace the portion of damaged tissue. There are three components of tissue engineering such as stem cells, scaffold, and signalizing molecules. Scaffold is used for the growth and development of cells as well as for providing mechanical strength to the cells. Moreover, scaffold-based platforms in 3D cell culture are used to alter the cell culture procedure by providing a surface on which the cells can easily impart 3D growth.
In scaffold technology, the cells are grown within extracellular matrix or synthetic materials. Cell adhesion, proliferation, and activation depend on scaffold material properties and scaffold characteristics. To accomplish the required mechanical function and rate of new-tissue formation, different characteristics, such as materials, degradation kinetic, and scaffold properties, should be altered to match the specific application.
Pore distribution, porosity, and exposed surface area of the scaffold can influence the architecture of the extracellular matrix, penetration, rate of penetration of cells, and the final effectiveness of regenerative process. The growth of the global scaffold technology market is majorly driven by rise in demand for body reconstruction procedures and tissue engineering, increase in usage of biomaterials, and growth of technological advancement of scaffold technology.
However, high costs associated with implementation and emergence of scaffold-free technology for cell culturing are expected to hamper the growth of the market. On the contrary, increase in expenditure on R&D by governments in developing countries has high growth potential in these countries.
The scaffold technology market is categorized on the basis of product type, type, application, end user, and region. Depending on product type, the market is divided into natural scaffold and synthetic scaffold. By type, the scaffold technology market is divided into macro-porous scaffolds, micro-porous scaffolds, nano-porous scaffolds, and solid scaffolds. By application, the market is fragmented into cancer cell research, stem cell research, drug discovery, and regenerative medicine. By end user, the market is classified into biotechnology & pharmaceutical companies, contract research laboratories, and academic institutes. Region wise, the market is analyzed across North America (the U.S., Canada, and Mexico), Europe (Germany, France, the UK, and Rest of Europe), Asia-Pacific (Japan, China, India, Australia, and Rest of Asia-Pacific), and LAMEA (Brazil, Saudi Arabia, South Africa, and Rest of LAMEA).
North America accounted for the largest market share in the viral clearance market in 2021 and is expected to retain its dominance throughout the forecast period. This is primarily attributed to increase in demand for biopharmaceutical and upsurge in demand for advanced technologies in the purification of recombinant proteins produced by animal cell cultures to create high-value products of modern biotechnology.
The report provides a comprehensive competitive analysis of prominent market players such as 3D Biotek LLC, Bico Group, Agilent Technologies, Inc. (Biotek), BioVison Incorporated, Corning Incorporated, Merck KGaA (Sigmaaldrich), PromoCell GmbH, Reprocell, Incorporation, Synthecon, Incorporated, and Thermo Fisher Scientific Inc.
An in-depth analysis of various regions is anticipated to provide a detailed understanding of the current trends to enable stakeholders to formulate region-specific plans.
Tissue engineering covers a wide range of applications that repair or replace the portion of damaged tissue. There are three components of tissue engineering such as stem cells, scaffold, and signalizing molecules. Scaffold is used for the growth and development of cells as well as for providing mechanical strength to the cells. Moreover, scaffold-based platforms in 3D cell culture are used to alter the cell culture procedure by providing a surface on which the cells can easily impart 3D growth.
In scaffold technology, the cells are grown within extracellular matrix or synthetic materials. Cell adhesion, proliferation, and activation depend on scaffold material properties and scaffold characteristics. To accomplish the required mechanical function and rate of new-tissue formation, different characteristics, such as materials, degradation kinetic, and scaffold properties, should be altered to match the specific application.
Pore distribution, porosity, and exposed surface area of the scaffold can influence the architecture of the extracellular matrix, penetration, rate of penetration of cells, and the final effectiveness of regenerative process. The growth of the global scaffold technology market is majorly driven by rise in demand for body reconstruction procedures and tissue engineering, increase in usage of biomaterials, and growth of technological advancement of scaffold technology.
However, high costs associated with implementation and emergence of scaffold-free technology for cell culturing are expected to hamper the growth of the market. On the contrary, increase in expenditure on R&D by governments in developing countries has high growth potential in these countries.
The scaffold technology market is categorized on the basis of product type, type, application, end user, and region. Depending on product type, the market is divided into natural scaffold and synthetic scaffold. By type, the scaffold technology market is divided into macro-porous scaffolds, micro-porous scaffolds, nano-porous scaffolds, and solid scaffolds. By application, the market is fragmented into cancer cell research, stem cell research, drug discovery, and regenerative medicine. By end user, the market is classified into biotechnology & pharmaceutical companies, contract research laboratories, and academic institutes. Region wise, the market is analyzed across North America (the U.S., Canada, and Mexico), Europe (Germany, France, the UK, and Rest of Europe), Asia-Pacific (Japan, China, India, Australia, and Rest of Asia-Pacific), and LAMEA (Brazil, Saudi Arabia, South Africa, and Rest of LAMEA).
North America accounted for the largest market share in the viral clearance market in 2021 and is expected to retain its dominance throughout the forecast period. This is primarily attributed to increase in demand for biopharmaceutical and upsurge in demand for advanced technologies in the purification of recombinant proteins produced by animal cell cultures to create high-value products of modern biotechnology.
The report provides a comprehensive competitive analysis of prominent market players such as 3D Biotek LLC, Bico Group, Agilent Technologies, Inc. (Biotek), BioVison Incorporated, Corning Incorporated, Merck KGaA (Sigmaaldrich), PromoCell GmbH, Reprocell, Incorporation, Synthecon, Incorporated, and Thermo Fisher Scientific Inc.
KEY BENEFITS FOR STAKEHOLDERS
- This report provides a detailed quantitative analysis of the current market trends and future estimations from 2021 to 2031, which assists to identify the prevailing market opportunities.
An in-depth analysis of various regions is anticipated to provide a detailed understanding of the current trends to enable stakeholders to formulate region-specific plans.
- A comprehensive analysis of the factors that drive and restrain the growth of the scaffold technology market is provided.
- An extensive analysis of various regions provides insights that allow companies to strategically plan their business moves.
Key Market Segments
By Product Type
- Natural Scaffold
- Sythetic Scaffold
By Type
- Macro-Porous Scaffolds
- Micro-Porous Scaffolds
- Nano-Porous Scaffolds
- Solid Scaffolds
By Application
- Drug discovery
- Regenerative medicine
- Cancer cell research
- Stem cell research
By End User
- Biotechnology pharmaceutical companies
- Contract Research laboratories
- Academic Institutes
By Region
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- United Kingdom
- Rest of Europe
- Asia-Pacific
- Japan
- China
- India
- Australia
- Rest of Asia-Pacific
- LAMEA
- Brazil
- Saudi Arabia
- South Africa
- Rest of LAMEA
Key Market Players
- 3D Biotek, LLC
- Bico Group
- Avantor, Inc.
- Becton, Dickinson, and Company
- Corning Incorporated
- InSphero AG
- Lonza Group Ltd.
- Synthecon Incorporated
- Thermo Fisher Scientific Inc.
- ReproCELL Incorporated
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Table of Contents
CHAPTER 1: INTRODUCTION
CHAPTER 2: EXECUTIVE SUMMARY
CHAPTER 3: MARKET OVERVIEW
CHAPTER 4: SCAFFOLD TECHNOLOGY MARKET, BY PRODUCT TYPE
CHAPTER 5: SCAFFOLD TECHNOLOGY MARKET, BY TYPE
CHAPTER 6: SCAFFOLD TECHNOLOGY MARKET, BY APPLICATION
CHAPTER 7: SCAFFOLD TECHNOLOGY MARKET, BY END USER
CHAPTER 8: SCAFFOLD TECHNOLOGY MARKET, BY REGION
CHAPTER 9: COMPANY LANDSCAPE
CHAPTER 10: COMPANY PROFILES
List of Tables
List of Figures
Executive Summary
According to the report, titled, “Scaffold Technology Market," the scaffold technology market was valued at $1.02 billion in 2021, and is estimated to reach $5.09 billion by 2031, growing at a CAGR of 18% from 2022 to 2031.Scaffolds mimic the extracellular matrix of the native tissue, recapitulating the in vivo milieu and allowing cells to influence their own microenvironments. They usually serve purposes such as allow cell attachment and migration, deliver & retain cells and biochemical factors, and exert certain mechanical & biological influences to modify the behavior of the cell phase.
In addition, scaffold can act as a delivery vehicle for exogenous cells and matrix for cell adhesion to facilitate certain unit cell processes (for example, mitosis, synthesis, migration) of cells in vivo or for cells seeded in vitro. It also serves as a barrier to prevent the infiltration of surrounding tissue that may impede the process of regeneration. Scaffold technology technique is gaining popularity in the healthcare research sector, owing to increased demand for body reconstruction procedures and tissue engineering.
Scaffold is a biomaterial that initiates tissue growth in regenerative medicine, and its presence allows cells to generate biological structural components of the extracellular matrix in culture environment. Moreover, natural polymers scaffold shows better fit to the microenvironment of tissues and promotes desirable cellular responses, degradability, and biocompatibility.
Depending on product type, the natural scaffold segment dominated the market in 2021, and is expected to continue this trend throughout the forecast period, owing to growing research in the field of tissue engineering and regenerative medicine to develop novel scaffolds for remodeling of biological tissues.
Based on type, the micro-porous scaffolds segment holds the largest market share, owing to advantages offered by micro-porous scaffold such as high product demand in tissue engineering for liver, bladder, nerve, skin, bone, cartilage, and ligament. Moreover, micro-porous scaffold enables organ-on-a-chip technology to enhance in vivo wound healing. Therefore, this segment is expected to dominate the product segment during the forecast period.
On the basis of application, the regenerative medicine segment is estimated to be the fastest-growing segment during the forecast period owing to successful advancements in regenerative medicine therapies.
Based on end user, the market is segmented into biotechnology & pharmaceutical companies, contract research laboratories, and academic institutes. The academic institutes segment dominated the scaffold technology market size in 2021, registering a CAGR of 18.2% from 2022 to 2031. This growth is attributed to upsurge in collaborations between academic institutions and biotechnology & pharmaceutical companies worldwide.
Several companies collaborate with the laboratories for conducting basic research to eventually reducing the overall time required for the completion of the research. Contract research laboratories segment is expected to grow rapidly by 2031, registering a CAGR of 18.6% during the forecast period, owing to the increased need to provide diagnostic services to biopharmaceutical companies and research laboratories for performing research activities.
By region, North America accounted for the largest market share in 2021, and is anticipated to maintain its dominance from 2022 to 2031 due to the presence of large pharmaceutical and biotechnology companies that use scaffold technology in 3D culture in collaboration with research institutes and clinical laboratories for developing regenerative medicines and drug discovery & development. Furthermore, rise in demand for organ transplantation and surge in R&D activities focused on technologically advanced solutions are predicted to fuel the adoption of 3D cell culture practices in the region.
In addition, surge in incidences of cancer has led the government to increase the funding and grants for R&D in the field of cancer, which may have a positive impact on the scaffold technology market trends. Moreover, strategic expansion of biotechnological and pharmaceutical companies has led to launch of advanced products, which is expected to augment the market growth in the coming years.
The report provides a comprehensive analysis of the key players that operate in the global scaffold technology market. The key companies profiled in the report include 3D Biotek LLC, Advanced Biomatrix, Inc., Agilent Technologies, Inc. (Biotek), BioVison, Incorporated, Corning Incorporated, Merck KGaA (Sigmaaldrich), PromoCell GmbH, Reprocell, Incorporation, Synthecon, Incorporated, and Thermo Fisher Scientific Inc.
Key Findings of the Study
- On the basis of product type, the natural scaffolds segment held 62.86% share in the global Scaffold Technology Market growth in 2021.
- On the basis of type, the micro-porous scaffolds segment held the largest market share in 2021, and is expected to remain dominant throughout the forecast period.
- On the basis of application, the cancer research segment held the largest market share in 2021, and is expected to remain dominant throughout the forecast period.
- On the basis of end user, the academic institutes segment held the largest share in biodegradable scaffold industry in 2021, and is expected to remain dominant throughout the forecast period.
- Region-wise, North America dominated the scaffold technology market share in 2021, and is expected to be dominant during the forecast period, owing to rise in incidences of cancer, increase in number of organ transplantation, and expansion of biotechnology & pharmaceutical companies.
Companies Mentioned
- 3D Biotek, LLC
- Bico Group
- Avantor, Inc.
- Becton, Dickinson, and Company
- Corning Incorporated
- Insphero AG
- Lonza Group Ltd.
- Synthecon Incorporated
- Thermo Fisher Scientific Inc.
- Reprocell Incorporated
Methodology
The analyst offers exhaustive research and analysis based on a wide variety of factual inputs, which largely include interviews with industry participants, reliable statistics, and regional intelligence. The in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. The primary research efforts include reaching out participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions.
They are also in professional corporate relations with various companies that allow them greater flexibility for reaching out to industry participants and commentators for interviews and discussions.
They also refer to a broad array of industry sources for their secondary research, which typically include; however, not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic news articles and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecast
Furthermore, the accuracy of the data will be analyzed and validated by conducting additional primaries with various industry experts and KOLs. They also provide robust post-sales support to clients.
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Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 254 |
| Published | July 2022 |
| Forecast Period | 2021 - 2031 |
| Estimated Market Value ( USD | $ 1026 million |
| Forecasted Market Value ( USD | $ 5095.3 million |
| Compound Annual Growth Rate | 17.4% |
| Regions Covered | Global |
| No. of Companies Mentioned | 10 |
