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Recurrent Clostridioides difficile Infection (rCDI) - Pipeline Insight, 2024

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    Drug Pipelines

  • 60 Pages
  • April 2024
  • Region: Global
  • DelveInsight
  • ID: 5692366
This “Recurrent Clostridioides difficile Infection (r CDI) - Pipeline Insight, 2024,” report provides comprehensive insights about 5+ companies and 5+ pipeline drugs in Recurrent Clostridioides difficile Infection (r CDI) pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products inthisspace.

Geography Covered

  • Global coverage

Recurrent Clostridioides difficile Infection (r CDI)Understanding

Recurrent Clostridioides difficile Infection (r CDI):Overview

Clostridioides difficile is a gram-positive bacterium that is the cause most implicated in antibiotic-associated diarrhea. The emergence of a newer hypervirulent strain North American pulsed-field gel electrophoresis type 1 (NAP1) has been attributed to the increase in incidence and severity of C. difficile infections (CDI) over the last decade. C. difficile colonizes in the large intestine of humans. Healthy adults with adequate immune response become asymptomatic carriers of the disease. Neonates also have a high rate of asymptomatic carrier rate, owing to a lack of intestinal receptors for C. difficile. The use of antibiotics alters the microbial flora of the large intestine, rendering it susceptible to infection by C. difficile, and the transmission of the disease occurs through the fecal-oral route.

Recurrent Clostridioides difficile Infection (r CDI) - Pipeline Insight, 2024 report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Recurrent Clostridioides difficile Infection (r CDI) pipeline landscape is provided which includes the disease overview and Recurrent Clostridioides difficile Infection (rCDI) treatment guidelines. The assessment part of the report embraces, in depth Recurrent Clostridioides difficile Infection (rCDI) commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, licensing, mergers and acquisition, funding, designations and other productrelateddetails.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence in Recurrent Clostridioides difficile Infection (r CDI) R&D. The therapies under development are focused on novel approaches to treat/improve in Recurrent Clostridioides difficile Infection(rCDI).

This segment of the Recurrent Clostridioides difficile Infection (r CDI) report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and pressreleases.

Recurrent Clostridioides difficile Infection (r CDI) EmergingDrugs

RBX7455: Rebiotix RBX2660 is an investigational microbiota-based live biotherapeutic studied for its potential to reduce recurrence of C. difficile infection after antibiotic treatment. RBX2660 has been granted Fast Track, Orphan, and Breakthrough Therapy designations from the U.S. Food and Drug Administration (FDA). RBX2660 was developed by Rebiotix, a Ferringcompany.

Recurrent Clostridioides difficile Infection (r CDI): TherapeuticAssessment

This segment of the report provides insights about the different Recurrent Clostridioides difficile Infection (r CDI) drugs segregated based on following parameters that define the scope of the report, suchas:

Major Players in Recurrent Clostridioides difficile Infection (rCDI)

There are approx. 5+ key companies which are developing the therapies for Recurrent Clostridioides difficile Infection (r CDI). The companies which have their Recurrent Clostridioides difficile Infection (r CDI) drug candidates in the most advanced stage, i.e. Phase IIIinclude,Rebiotix.

Phases

This report covers around 5+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates

Route of Administration

Recurrent Clostridioides difficile Infection (r CDI) pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs suchas
  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical
Molecule Type

Products have been categorized under various Molecule types such as

  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Recurrent Clostridioides difficile Infection (r CDI): Pipeline DevelopmentActivities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Recurrent Clostridioides difficile Infection (r CDI) therapeutic drugs key players involved in developing keydrugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Recurrent Clostridioides difficile Infection (r CDI)drugs.

Recurrent Clostridioides difficile Infection (r CDI) ReportInsights

  • Recurrent Clostridioides difficile Infection (r CDI) PipelineAnalysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Recurrent Clostridioides difficile Infection (r CDI) ReportAssessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Recurrent Clostridioides difficile Infection (r CDI)drugs?
  • How many Recurrent Clostridioides difficile Infection (r CDI) drugs are developed by eachcompany?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Recurrent Clostridioides difficile Infection (rCDI)?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Recurrent Clostridioides difficile Infection (rCDI)?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Recurrent Clostridioides difficile Infection (r CDI) and theirstatus?
  • What are the key designations that have been granted to the emerging drugs?

Key Players

  • Vedanta Biosciences
  • Rebiotix
  • Takeda
  • Adiso Therapeutics
  • Lumen Bioscience

Key Products

  • RBX7455
  • VE303
  • VP20621
  • ART24
  • LMN201


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Table of Contents

IntroductionExecutive Summary
Recurrent Clostridioides difficile Infection (rCDI) : Overview
  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management
Pipeline Therapeutics
  • Comparative Analysis
Therapeutic Assessment
  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type
Recurrent Clostridioides difficile Infection (rCDI) - Analytical Perspective
Late Stage Products (Phase III)
  • Comparative Analysis
RBX 7455: Rebiotix
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
  • Comparative Analysis
VP20621: Takeda
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
  • Comparative Analysis
Drug name: Company name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
  • Comparative Analysis
ADS 024: Adiso Therapeutics
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Preclinical and Discovery Stage Products
  • Comparative Analysis
Drug name: Company name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
  • Comparative Analysis
Recurrent Clostridioides difficile Infection (rCDI) Key CompaniesRecurrent Clostridioides difficile Infection (rCDI) Key ProductsRecurrent Clostridioides difficile Infection (rCDI) - Unmet NeedsRecurrent Clostridioides difficile Infection (rCDI) - Market Drivers and BarriersRecurrent Clostridioides difficile Infection (rCDI) - Future Perspectives and ConclusionRecurrent Clostridioides difficile Infection (rCDI) Analyst ViewsRecurrent Clostridioides difficile Infection (rCDI) Key CompaniesAppendix
List of Tables
Table 1 Total Products for Recurrent Clostridioides difficile Infection (rCDI)
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
List of Figures
Figure 1 Total Products for Recurrent Clostridioides difficile Infection (rCDI)
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Vedanta Biosciences
  • Rebiotix
  • Takeda
  • Adiso Therapeutics
  • Lumen Bioscience