The North America 3D Cell Culture Market should witness market growth of 14.7% CAGR during the forecast period (2022-2028).
Cellular communication and the formation of extracellular matrices are more similar in 3D spheroids to in vivo tissue. These matrices enable the cells to migrate within their spheroid in a manner similar to how they would move in live tissue. Therefore, spheroids are superior models for cell differentiation, migration, survival, and growth.
Moreover, 3D cell cultures provide a more accurate representation of cell polarization than 2D cultures, in which cells can only be moderately polarized. In addition, 3D-grown cells demonstrate distinct gene expression from 2D-grown cells. The third dimension of cell expansion provides an additional contact area for mechanical inputs and cell adhesion, which is required for integrin ligation, cell contraction, and even intracellular signaling.
Normal solute transport and binding to effector proteins (such as growth factors and enzymes) are dependent on the 3D cellular matrix, hence it is essential for the formation of tissue-scale solute concentration gradients. As the gene expression of 3D spheroids more closely resembles gene expression in vivo, testing gene expression of in vitro cell cultures in 3D is significantly more useful for drug toxicological screening than testing gene expression of 2D cells.
This approach allows a significant proportion of the population to be considered for the trial, hence improving the study, involvement, recruitment, and retention. Volunteers, researchers, as well as clinical research coordinators can save a tremendous amount of time, effort, and stress by participating in virtual clinical studies. Moreover, the United States market is very competitive due to the presence of various multinational firms.
The US market dominated the North America 3D Cell Culture Market by Country in 2021, and would continue to be a dominant market till 2028; thereby, achieving a market value of $888.2 million by 2028. The Canada market is poised to grow at a CAGR of 17.3% during (2022-2028). Additionally, The Mexico market should witness a CAGR of 16.3% during (2022-2028).
Based on Type, the market is segmented into Scaffold-based, Scaffold-free, Microfluidics-based, and Magnetic & Bioprinted. Based on Application, the market is segmented into Cancer & Stem Cell Research, Drug Discovery & Toxicology Testing, and Tissue Engineering & Regenerative Medicine. Based on End-user, the market is segmented into Pharmaceutical & Biotechnology Companies, Research Institutes, Cosmetic Industry, and Others. Based on countries, the market is segmented into U.S., Mexico, Canada, and Rest of North America.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Thermo Fisher Scientific, Inc., Merck Group, Avantor, Inc., Corning Incorporated, Lonza Group AG, Mimetas B.V., Insphero AG, Emulate, Inc., Tecan Group Ltd., and CN Bio Innovations Ltd.
Cellular communication and the formation of extracellular matrices are more similar in 3D spheroids to in vivo tissue. These matrices enable the cells to migrate within their spheroid in a manner similar to how they would move in live tissue. Therefore, spheroids are superior models for cell differentiation, migration, survival, and growth.
Moreover, 3D cell cultures provide a more accurate representation of cell polarization than 2D cultures, in which cells can only be moderately polarized. In addition, 3D-grown cells demonstrate distinct gene expression from 2D-grown cells. The third dimension of cell expansion provides an additional contact area for mechanical inputs and cell adhesion, which is required for integrin ligation, cell contraction, and even intracellular signaling.
Normal solute transport and binding to effector proteins (such as growth factors and enzymes) are dependent on the 3D cellular matrix, hence it is essential for the formation of tissue-scale solute concentration gradients. As the gene expression of 3D spheroids more closely resembles gene expression in vivo, testing gene expression of in vitro cell cultures in 3D is significantly more useful for drug toxicological screening than testing gene expression of 2D cells.
This approach allows a significant proportion of the population to be considered for the trial, hence improving the study, involvement, recruitment, and retention. Volunteers, researchers, as well as clinical research coordinators can save a tremendous amount of time, effort, and stress by participating in virtual clinical studies. Moreover, the United States market is very competitive due to the presence of various multinational firms.
The US market dominated the North America 3D Cell Culture Market by Country in 2021, and would continue to be a dominant market till 2028; thereby, achieving a market value of $888.2 million by 2028. The Canada market is poised to grow at a CAGR of 17.3% during (2022-2028). Additionally, The Mexico market should witness a CAGR of 16.3% during (2022-2028).
Based on Type, the market is segmented into Scaffold-based, Scaffold-free, Microfluidics-based, and Magnetic & Bioprinted. Based on Application, the market is segmented into Cancer & Stem Cell Research, Drug Discovery & Toxicology Testing, and Tissue Engineering & Regenerative Medicine. Based on End-user, the market is segmented into Pharmaceutical & Biotechnology Companies, Research Institutes, Cosmetic Industry, and Others. Based on countries, the market is segmented into U.S., Mexico, Canada, and Rest of North America.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Thermo Fisher Scientific, Inc., Merck Group, Avantor, Inc., Corning Incorporated, Lonza Group AG, Mimetas B.V., Insphero AG, Emulate, Inc., Tecan Group Ltd., and CN Bio Innovations Ltd.
Scope of the Study
By Type
- Scaffold-based
- Scaffold-free
- Microfluidics-based
- Magnetic & Bioprinted
By Application
- Cancer & Stem Cell Research
- Drug Discovery & Toxicology Testing
- Tissue Engineering & Regenerative Medicine
By End-user
- Pharmaceutical & Biotechnology Companies
- Research Institutes
- Cosmetic Industry
- Others
By Country
- US
- Canada
- Mexico
- Rest of North America
Key Market Players
List of Companies Profiled in the Report:
- Thermo Fisher Scientific, Inc.
- Merck Group
- Avantor, Inc.
- Corning Incorporated
- Lonza Group AG
- Mimetas B.V.
- Insphero AG
- Emulate, Inc.
- Tecan Group Ltd.
- CN Bio Innovations Ltd.
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Table of Contents
Chapter 1. Market Scope & Methodology
Chapter 2. Market Overview
Chapter 3. Competition Analysis - Global
Chapter 4. North America 3D Cell Culture Market by Type
Chapter 5. North America 3D Cell Culture Market by Application
Chapter 6. North America 3D Cell Culture Market by End-user
Chapter 7. North America 3D Cell Culture Market by Country
Chapter 8. Company Profiles
Companies Mentioned
- Thermo Fisher Scientific, Inc.
- Merck Group
- Avantor, Inc.
- Corning Incorporated
- Lonza Group AG
- Mimetas B.V.
- Insphero AG
- Emulate, Inc.
- Tecan Group Ltd.
- CN Bio Innovations Ltd.
Methodology
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