The Europe Sustained Release Excipients Market should witness market growth of 8.1% CAGR during the forecast period (2022-2028).
Methacrylate polymers, which also offer gastro-resistant functionality, are frequently utilized in delayed-release dosage forms. Although the usage of two-polymer matrix systems is expanding, hydroxypropyl methylcellulose (HPMC) remains the excipient of choice in monolithic delivery systems. Matrix systems and functional coatings are the two main formulation techniques that can be used to create sustained release kinetics.
In order to produce a membrane surrounding the tablet that regulates the pace of API release in relation to the rate of coating layer evaporation through which the medicine will diffuse and dissolve, functional coatings are used. These reservoir systems are another name for such sustained release systems. This strategy can be flexible because the pores, coating type, and thickness can all be changed to alter the controlled release profile. The API is uniformly disseminated within a matrix made of polymers in formulations for sustained release based on a matrix.
Matrix systems are divided into hydrophobic and hydrophilic matrix systems based on the rate-controlling polymeric characteristics, which exhibit various release mechanisms. The API is released by diffusion through the thick gel layer and also by matrix erosion in the hydrophilic type of matrix systems. In this, the polymer hydrates and expands upon contact with the gastrointestinal medium, generating a gel layer on the system's surface. Different polymer kinds, grades, and quantities can be used to modify released kinetics, but they also depend on the solubility of the API.
Due to the aging populations, non-communicable diseases, multimorbidity, and frailty in Europe, the emergence of diseases like COVID-19 are especially pertinent. A study conducted throughout the region reported that the nations with the largest percentages of senior citizens were Finland, Italy, Greece, Portugal, and Germany. The report indicated that in these countries older people were living with disabilities on average. But the greatest rates were found in Bulgaria, Croatia, and Hungary. Additionally, the region's burden of cardiovascular diseases (CVD) goes beyond mortality. A high prevalence of the disease/disorder is observed in Eastern Europe than in the western part.
The Germany market dominated the Europe Sustained Release Excipients Market by Country in 2021; thereby, achieving a market value of $153.4 million by 2028. The UK market would showcase a CAGR of 7.2% during (2022-2028). Additionally, The France market is anticipated to grow at a CAGR of 8.9% during (2022-2028).
Based on Route of Administration, the market is segmented into Oral, Transdermal, Vaginal, Intravenous, Ophthalmic, Subcutaneous, Intramuscular, and Others. Based on Product, the market is segmented into Polymers, Minerals, Sugars, Gelatin & Chitosan, and Others. Based on Technology, the market is segmented into Targeted Delivery, Implants, Wurster Technique, Transdermal, Micro Encapsulation, and Coacervation & Others. Based on countries, the market is segmented into Germany, UK, France, Russia, Spain, Italy, and Rest of Europe.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include BASF SE, International Flavors & Fragrances, Inc., Ashland Global Holdings Inc., Evonik Industries AG, Croda International Plc, Gattefossé, Merck Group, Pfizer, Inc., Novartis AG and AstraZeneca Plc.
Methacrylate polymers, which also offer gastro-resistant functionality, are frequently utilized in delayed-release dosage forms. Although the usage of two-polymer matrix systems is expanding, hydroxypropyl methylcellulose (HPMC) remains the excipient of choice in monolithic delivery systems. Matrix systems and functional coatings are the two main formulation techniques that can be used to create sustained release kinetics.
In order to produce a membrane surrounding the tablet that regulates the pace of API release in relation to the rate of coating layer evaporation through which the medicine will diffuse and dissolve, functional coatings are used. These reservoir systems are another name for such sustained release systems. This strategy can be flexible because the pores, coating type, and thickness can all be changed to alter the controlled release profile. The API is uniformly disseminated within a matrix made of polymers in formulations for sustained release based on a matrix.
Matrix systems are divided into hydrophobic and hydrophilic matrix systems based on the rate-controlling polymeric characteristics, which exhibit various release mechanisms. The API is released by diffusion through the thick gel layer and also by matrix erosion in the hydrophilic type of matrix systems. In this, the polymer hydrates and expands upon contact with the gastrointestinal medium, generating a gel layer on the system's surface. Different polymer kinds, grades, and quantities can be used to modify released kinetics, but they also depend on the solubility of the API.
Due to the aging populations, non-communicable diseases, multimorbidity, and frailty in Europe, the emergence of diseases like COVID-19 are especially pertinent. A study conducted throughout the region reported that the nations with the largest percentages of senior citizens were Finland, Italy, Greece, Portugal, and Germany. The report indicated that in these countries older people were living with disabilities on average. But the greatest rates were found in Bulgaria, Croatia, and Hungary. Additionally, the region's burden of cardiovascular diseases (CVD) goes beyond mortality. A high prevalence of the disease/disorder is observed in Eastern Europe than in the western part.
The Germany market dominated the Europe Sustained Release Excipients Market by Country in 2021; thereby, achieving a market value of $153.4 million by 2028. The UK market would showcase a CAGR of 7.2% during (2022-2028). Additionally, The France market is anticipated to grow at a CAGR of 8.9% during (2022-2028).
Based on Route of Administration, the market is segmented into Oral, Transdermal, Vaginal, Intravenous, Ophthalmic, Subcutaneous, Intramuscular, and Others. Based on Product, the market is segmented into Polymers, Minerals, Sugars, Gelatin & Chitosan, and Others. Based on Technology, the market is segmented into Targeted Delivery, Implants, Wurster Technique, Transdermal, Micro Encapsulation, and Coacervation & Others. Based on countries, the market is segmented into Germany, UK, France, Russia, Spain, Italy, and Rest of Europe.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include BASF SE, International Flavors & Fragrances, Inc., Ashland Global Holdings Inc., Evonik Industries AG, Croda International Plc, Gattefossé, Merck Group, Pfizer, Inc., Novartis AG and AstraZeneca Plc.
Scope of the Study
By Route of Administration
- Oral
- Transdermal
- Vaginal
- Intravenous
- Ophthalmic
- Subcutaneous
- Intramuscular
- Others
By Product
- Polymers
- Minerals
- Sugars
- Gelatin & Chitosan
- Others
By Technology
- Targeted Delivery
- Implants
- Wurster Technique
- Transdermal
- Micro Encapsulation
- Coacervation & Others
By Country
- Germany
- UK
- France
- Russia
- Spain
- Italy
- Rest of Europe
Key Market Players
List of Companies Profiled in the Report:
- BASF SE
- International Flavors & Fragrances, Inc.
- Ashland Global Holdings Inc.
- Evonik Industries AG
- Croda International Plc
- Gattefossé
- Merck Group
- Pfizer, Inc.
- Novartis AG
- AstraZeneca Plc
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- Exhaustive coverage
- The highest number of market tables and figures
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Table of Contents
Chapter 1. Market Scope & Methodology
Chapter 2. Market Overview
Chapter 4. Europe Sustained Release Excipients Market by Route of Administration
Chapter 5. Europe Sustained Release Excipients Market by Product
Chapter 6. Europe Sustained Release Excipients Market by Technology
Chapter 7. Europe Sustained Release Excipients Market by Country
Chapter 8. Company Profiles
Companies Mentioned
- BASF SE
- International Flavors & Fragrances, Inc.
- Ashland Global Holdings Inc.
- Evonik Industries AG
- Croda International Plc
- Gattefossé
- Merck Group
- Pfizer, Inc.
- Novartis AG
- AstraZeneca Plc
Methodology
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