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Asia Pacific Digital Pathology Market Forecast to 2028 - COVID-19 Impact and Regional Analysis By Product, Application, and End User

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    Report

  • 167 Pages
  • November 2022
  • Region: Asia Pacific
  • The Insight Partners
  • ID: 5701723
UP TO OFF until Jun 30th 2024
The digital pathology market in Asia Pacific is expected to grow from US$ 206.30 million in 2022 to US$ 426.03 million by 2028. It is estimated to grow at a CAGR of 12.8% from 2022 to 2028.

Drug development is a time-consuming and labour-intensive process. Scientists and pathologists check numerous samples to evaluate how a drug affects a specific tissue or animal. Digital pathology and artificial intelligence (AI) can be employed in this process to improve overall efficiency. Toxicological research generates a vast number of slides, and just adding digital imaging and AI to the workflow may cut down on work hours. This enables pathologists to specifically focus on slides with variations, such as lesions, which are essential to understand drug mechanisms. Moreover, digital image processing enables the extrapolation and memorization of enormous volumes of data from the image than a researcher can do. Furthermore, computers can store everything they have been programmed for, which helps create an information-rich database. Further, the process of collecting, analyzing, and sharing data becomes effortless. Digitized information can be shared with anyone and with anywhere in the world, and pathologists can access the data from remote locations as well. All these aspects result in a structured, effective, high-quality, and focused drug research. Moreover, digital pathology offers pathologists the flexibility to collaborate with anyone on significantly specialized projects, further improving drug discovery in Asia Pacific.

Pharmaceutical manufacturers are harnessing the benefits of digital pathology in drug development. For instance, in April 2022, GlaxoSmithKline (GSK) recruited PathAI to bring digital pathology AI to cancer and NASH drug development. GSK and PathAI signed a multiyear pact for joining forces to improve the drugmaker's molecule discovery and clinical trial work in NASH and across its oncology portfolio.

Market Overview

The Asia Pacific digital pathology market is segmented into China, Japan, India, Australia, South Korea, and the rest of Asia Pacific. The market growth in Asia Pacific is attributed to major factors such as the rising initiatives and support by the government of China, growing cancer cases, increasing focus by industry players in Japan, and developing healthcare infrastructure in India. Digital pathology scanner plays a vital role in the early diagnosis of cancer, and further in its treatment. Images of the cancerous tissues are obtained with the help of digital pathology scanners and analyzed with software. Progress in digital pathology systems enabled the visualization of images and the analysis of these tissues, thereby aiding in cancer treatment. According to Globocan report, in 2020, around 1,028,658 new cancer cases were found in Japan, and 420,124 cancer deaths were recorded in the country. To reduce the number of cancer cases, Japan focuses on improving the early diagnosis of cancer. Furthermore, a few national level conferences are also being arranged in the country to provide the knowledge and lectures on the various cancer diagnosis. For instance, Asia Pacific Summit on Oncology & Cancer was held in May 2017. The aim of this conference was cancer biopsy and imaging tests and diagnostics. Owing to these developments and focus by industry players in Japan the digital pathology market is likely grow in the forecast period.

Asia Pacific Digital Pathology Market Segmentation

The Asia Pacific digital pathology market is segmented into product , type , application and end user.
  • Based on product, the market is segmented into scanners, software, storage and communication systems. The scanners segment registered the largest market share in 2022.
  • Based on type, the market is segmented into human pathology, and veterinary pathology. The human pathology segment held the larger market share in 2022.
  • Based on application, the market is segmented into drug discovery, disease diagnostics, teleconsultation, and training & education. The drug discovery segment held the larger market share in 2022.
  • Based on end user, the market is segmented into pharma and biotech companies, hospital, and academic. The pharma and biotech companies segment held the largest market share in 2022.
  • Based on country, the market is segmented into Japan, China, India, Australia, South Korea, and the Rest of Asia Pacific. Japan dominated the market share in 2022. Koninklijke Philips N.V.; Nikon Corporation; PerkinElmer, Inc.; Indica Labs; 3DHISTECH Ltd.; Hamamatsu Photonics K.K.; F. Hoffmann-La Roche Ltd; Visiopharm A/S; Glencoe Software, Inc., and Danaher Corporation. are the leading companies operating in the digital pathology in the region.

Table of Contents

1. Introduction
1.1 Scope of the Study
1.2 Research Report Guidance
1.3 Market Segmentation
1.3.1 Asia Pacific Digital Pathology Market - By Product
1.3.2 Asia Pacific Digital Pathology Market - By Type
1.3.3 Asia Pacific Digital Pathology Market - By Application
1.3.4 Asia Pacific Digital Pathology Market - By End User
1.3.5 Asia Pacific Digital Pathology Market - By Country
2. Key Takeaways
3. Research Methodology
3.1 Coverage
3.2 Secondary Research
3.3 Primary Research
4. Asia Pacific Digital Pathology Market - Market Landscape
4.1 Overview
4.2 PEST Analysis
4.2.1 Asia Pacific PEST Analysis
4.3 Experts Opinion
5. Asia Pacific Digital Pathology Market - Key Market Dynamics
5.1 Market Drivers
5.1.1 Technological Advancements in Digital Pathology Systems
5.1.2 Growing Preference for Telepathology in Remote Areas
5.1.3 Use of Digital Pathology for Cancer Diagnosis
5.2 Market Restraints
5.2.1 High Cost of Digital Pathology Systems
5.2.2 Shortage of Skilled Professionals to Operate Digital Pathology Systems
5.3 Market Opportunities
5.3.1 Use of Digital Pathology in Drug Development
5.4 Future Trends
5.4.1 Use of Artificial Intelligence
5.5 Impact Analysis
6. Digital Pathology Market - Asia Pacific Analysis
6.1 Asia Pacific Digital Pathology Market Revenue Forecast and Analysis
6.1.1 Asia Pacific: Digital Pathology Market, 2019-2028 (USD Million)
7. Asia Pacific Digital Pathology Market Revenue and Forecast to 2028 - by Product
7.1 Overview
7.2 Asia Pacific Digital Pathology Market, By Product 2022 & 2028 (%)
7.2.1 Asia Pacific: Digital Pathology Market, by Product, 2019-2028 (USD Million)
7.2.2 Asia Pacific: Digital Pathology Market, by Scanners, 2019-2028 (USD Million)
7.3 Scanners
7.3.1 Overview
7.3.2 Asia Pacific Scanners Market Revenue and Forecast to 2028 (US$ Mn)
7.3.3 Integrated
7.3.3.1 Overview
7.3.3.2 Asia Pacific Integrated Market Revenue and Forecast to 2028 (US$ Mn)
7.3.4 Standalone
7.3.4.1 Overview
7.3.4.2 Asia Pacific Standalone Market Revenue and Forecast to 2028 (US$ Mn)
7.4 Software
7.4.1 Overview
7.4.2 Asia Pacific Software Market Revenue and Forecast to 2028 (US$ Mn)
7.5 Communication System
7.5.1 Overview
7.5.2 Asia Pacific Communication System Market Revenue and Forecast to 2028 (US$ Mn)
7.6 Storage
7.6.1 Overview
7.6.2 Asia Pacific Storage Market Revenue and Forecast to 2028 (US$ Mn)
8. Asia Pacific Digital Pathology Market Analysis - by Type
8.1 Overview
8.2 Asia Pacific Digital Pathology Market Revenue Share, by Type (2022 and 2028)
8.2.1 Asia Pacific: Digital Pathology Market, by Type, 2019-2028 (USD Million)
8.3 Human Pathology
8.3.1 Overview
8.3.2 Asia Pacific Human Pathology: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
8.4 Veterinary Pathology
8.4.1 Overview
8.4.2 Asia Pacific Veterinary Pathology: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
9. Asia Pacific Digital Pathology Market Analysis - by Application
9.1 Overview
9.2 Asia Pacific Digital Pathology Market, By Application 2022 & 2028 (%)
9.2.1 Asia Pacific: Digital Pathology Market, by Application, 2019-2028 (USD Million)
9.3 Drug Discovery
9.3.1 Overview
9.3.2 Asia Pacific Drug Discovery Market Revenue and Forecast to 2028 (US$ Mn)
9.4 Disease Diagnostics
9.4.1 Overview
9.4.2 Asia Pacific Disease Diagnostics Market Revenue and Forecast to 2028 (US$ Mn)
9.5 Teleconsultation
9.5.1 Overview
9.5.2 Asia Pacific Teleconsultation Market Revenue and Forecast to 2028 (US$ Mn)
9.6 Training and Education
9.6.1 Overview
9.6.2 Asia Pacific Training and Education Market Revenue and Forecast to 2028 (US$ Mn)
10. Asia Pacific Digital Pathology Market Analysis - by End User
10.1 Overview
10.2 Asia Pacific Digital Pathology Market Revenue Share, by End User (2022 and 2028)
10.2.1 Asia Pacific: Digital Pathology Market, by End User, 2019-2028 (USD Million)
10.3 Pharma and Biotech Companies
10.3.1 Overview
10.3.2 Asia Pacific Pharma and Biotech Companies: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
10.4 Hospital
10.4.1 Overview
10.4.2 Asia Pacific Hospital: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
10.5 Academic
10.5.1 Overview
10.5.2 Asia Pacific Academic: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
11. Asia Pacific Digital Pathology Market Revenue and Forecast to 2028- by Country
11.1 Asia Pacific: Digital Pathology Market
11.1.1 Overview
11.1.3 Asia Pacific: Digital Pathology Market, by Country, 2022 & 2028 (%)
11.1.4 China: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.4.1 China: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.4.2 China: Digital Pathology Market, by Product, 2019-2028 (USD Million)
11.1.4.3 China: Digital Pathology Market, by Scanners, 2019-2028 (USD Million)
11.1.4.4 China: Digital Pathology Market, by Type, 2019-2028 (USD Million)
11.1.4.5 China: Digital Pathology Market, by Application, 2019-2028 (USD Million)
11.1.4.6 China: Digital Pathology Market, by End User, 2019-2028 (USD Million)
11.1.5 Japan: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.5.1 Japan: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.5.2 Japan: Digital Pathology Market, by Product, 2019-2028 (USD Million)
11.1.5.3 Japan: Digital Pathology Market, by Scanners, 2019-2028 (USD Million)
11.1.5.4 Japan: Digital Pathology Market, by Type, 2019-2028 (USD Million)
11.1.5.5 Japan: Digital Pathology Market, by Application, 2019-2028 (USD Million)
11.1.5.6 Japan: Digital Pathology Market, by End User, 2019-2028 (USD Million)
11.1.6 India: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.6.1 India: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.6.2 India: Digital Pathology Market, by Product, 2019-2028 (USD Million)
11.1.6.3 India: Digital Pathology Market, by Scanners, 2019-2028 (USD Million)
11.1.6.4 India: Digital Pathology Market, by Type, 2019-2028 (USD Million)
11.1.6.5 India: Digital Pathology Market, by Application, 2019-2028 (USD Million)
11.1.6.6 India: Digital Pathology Market, by End User, 2019-2028 (USD Million)
11.1.7 Australia: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.7.1 Australia: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.7.2 Australia: Digital Pathology Market, by Product, 2019-2028 (USD Million)
11.1.7.3 Australia: Digital Pathology Market, by Scanners, 2019-2028 (USD Million)
11.1.7.4 Australia: Digital Pathology Market, by Type, 2019-2028 (USD Million)
11.1.7.5 Australia: Digital Pathology Market, by Application, 2019-2028 (USD Million)
11.1.7.6 Australia: Digital Pathology Market, by End User, 2019-2028 (USD Million)
11.1.8 South Korea: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.8.1 South Korea: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.8.2 South Korea: Digital Pathology Market, by Product, 2019-2028 (USD Million)
11.1.8.3 South Korea: Digital Pathology Market, by Scanners, 2019-2028 (USD Million)
11.1.8.4 South Korea: Digital Pathology Market, by Type, 2019-2028 (USD Million)
11.1.8.5 South Korea: Digital Pathology Market, by Application, 2019-2028 (USD Million)
11.1.8.6 South Korea: Digital Pathology Market, by End User, 2019-2028 (USD Million)
11.1.9 Rest of Asia Pacific: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.9.1 Rest of Asia Pacific: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
11.1.9.2 Rest of Asia Pacific: Digital Pathology Market, by Product, 2019-2028 (USD Million)
11.1.9.3 Rest of Asia Pacific: Digital Pathology Market, by Scanners, 2019-2028 (USD Million)
11.1.9.4 Rest of Asia Pacific: Digital Pathology Market, by Type, 2019-2028 (USD Million)
11.1.9.5 Rest of Asia Pacific: Digital Pathology Market, by Application, 2019-2028 (USD Million)
11.1.9.6 Rest of Asia Pacific: Digital Pathology Market, by End User, 2019-2028 (USD Million)
12. Asia Pacific Digital Pathology Market -Industry Landscape
12.1 Overview
12.2 Growth Strategies in the Asia Pacific Digital Pathology Market (%)
12.3 Organic Developments
12.3.1 Overview
12.4 Inorganic Developments
12.4.1 Overview
13. Company Profiles
13.1 Koninklijke Philips N.V.
13.1.1 Key Facts
13.1.2 Business Description
13.1.3 Products and Services
13.1.4 Financial Overview
13.1.5 SWOT Analysis
13.1.6 Key Developments
13.2 Nikon Corporation
13.2.1 Key Facts
13.2.2 Business Description
13.2.3 Products and Services
13.2.4 Financial Overview
13.2.5 SWOT Analysis
13.2.6 Key Developments
13.3 Perkin Elmer, Inc.
13.3.1 Key Facts
13.3.2 Business Description
13.3.3 Products and Services
13.3.4 Financial Overview
13.3.5 SWOT Analysis
13.3.6 Key Developments
13.4 Indica Labs
13.4.1 Key Facts
13.4.2 Business Description
13.4.3 Products and Services
13.4.4 Financial Overview
13.4.5 SWOT Analysis
13.4.6 Key Developments
13.5 3DHISTECH Ltd.
13.5.1 Key Facts
13.5.2 Business Description
13.5.3 Products and Services
13.5.4 Financial Overview
13.5.5 SWOT Analysis
13.5.6 Key Developments
13.6 Hamamatsu Photonics K.K.
13.6.1 Key Facts
13.6.2 Business Description
13.6.3 Products and Services
13.6.4 Financial Overview
13.6.5 SWOT Analysis
13.6.6 Key Developments
13.7 F. Hoffmann-La Roche Ltd
13.7.1 Key Facts
13.7.2 Business Description
13.7.3 Products and Services
13.7.4 Financial Overview
13.7.5 SWOT Analysis
13.7.6 Key Developments
13.8 Visiopharm A/S
13.8.1 Key Facts
13.8.2 Business Description
13.8.3 Products and Services
13.8.4 Financial Overview
13.8.5 SWOT Analysis
13.8.6 Key Developments
13.9 Glencoe Software, Inc.
13.9.1 Key Facts
13.9.2 Business Description
13.9.3 Products and Services
13.9.4 Financial Overview
13.9.5 SWOT Analysis
13.9.6 Key Developments
13.10 Danaher Corporation
13.10.1 Key Facts
13.10.2 Business Description
13.10.3 Products and Services
13.10.4 Financial Overview
13.10.5 SWOT Analysis
13.10.6 Key Developments
14. Appendix
14.1 About the Publisher
14.2 Glossary of Terms, Digital Pathology Market
List of Tables
Table 1. Asia Pacific: Digital Pathology Market- Revenue and Forecast to 2028 (USD Million)
Table 2. Asia Pacific: Digital Pathology Market, by Product - Revenue and Forecast to 2028 (USD Million)
Table 3. Asia Pacific: Digital Pathology Market, by Scanners - Revenue and Forecast to 2028 (USD Million)
Table 4. Asia Pacific: Digital Pathology Market, by Type - Revenue and Forecast to 2028 (USD Million)
Table 5. Asia Pacific Digital Pathology Market, by Application - Revenue and Forecast to 2028 (USD Million)
Table 6. Asia Pacific Digital Pathology Market, by End User- Revenue and Forecast to 2028 (USD Million)
Table 7. China: Digital Pathology Market, by Product - Revenue and Forecast to 2028 (USD Million)
Table 8. China: Digital Pathology Market, by Scanners - Revenue and Forecast to 2028 (USD Million)
Table 9. China: Digital Pathology Market, by Type - Revenue and Forecast to 2028 (USD Million)
Table 10. China: Digital Pathology Market, by Application - Revenue and Forecast to 2028 (USD Million)
Table 11. China: Digital Pathology Market, by End User- Revenue and Forecast to 2028 (USD Million)
Table 12. Japan: Digital Pathology Market, by Product- Revenue and Forecast to 2028 (USD Million)
Table 13. Japan: Digital Pathology Market, by Scanners- Revenue and Forecast to 2028 (USD Million)
Table 14. Japan: Digital Pathology Market, by Type- Revenue and Forecast to 2028 (USD Million)
Table 15. Japan: Digital Pathology Market, by Application- Revenue and Forecast to 2028 (USD Million)
Table 16. Japan: Digital Pathology Market, by End User - Revenue and Forecast to 2028 (USD Million)
Table 17. India: Digital Pathology Market, by Product- Revenue and Forecast to 2028 (USD Million)
Table 18. India: Digital Pathology Market, by Scanners- Revenue and Forecast to 2028 (USD Million)
Table 19. India: Digital Pathology Market, by Type- Revenue and Forecast to 2028 (USD Million)
Table 20. India: Digital Pathology Market, by Application - Revenue and Forecast to 2028 (USD Million)
Table 21. India: Digital Pathology Market, by End User- Revenue and Forecast to 2028 (USD Million)
Table 22. Australia: Digital Pathology Market, by Product - Revenue and Forecast to 2028 (USD Million)
Table 23. Australia: Digital Pathology Market, by Scanners - Revenue and Forecast to 2028 (USD Million)
Table 24. Australia: Digital Pathology Market, by Type - Revenue and Forecast to 2028 (USD Million)
Table 25. Australia: Digital Pathology Market, by Application- Revenue and Forecast to 2028 (USD Million)
Table 26. Australia: Digital Pathology Market, by End User- Revenue and Forecast to 2028 (USD Million)
Table 27. South Korea: Digital Pathology Market, by Product - Revenue and Forecast to 2028 (USD Million)
Table 28. South Korea: Digital Pathology Market, by Scanners - Revenue and Forecast to 2028 (USD Million)
Table 29. South Korea: Digital Pathology Market, by Type - Revenue and Forecast to 2028 (USD Million)
Table 30. South Korea: Digital Pathology Market, by Application - Revenue and Forecast to 2028 (USD Million)
Table 31. South Korea: Digital Pathology Market, by End User- Revenue and Forecast to 2028 (USD Million)
Table 32. Rest of Asia Pacific: Digital Pathology Market, by Product - Revenue and Forecast to 2028 (USD Million)
Table 33. Rest of Asia Pacific: Digital Pathology Market, by Scanners - Revenue and Forecast to 2028 (USD Million)
Table 34. Rest of Asia Pacific: Digital Pathology Market, by Type - Revenue and Forecast to 2028 (USD Million)
Table 35. Rest of Asia Pacific: Digital Pathology Market, by Application - Revenue and Forecast to 2028 (USD Million)
Table 36. Rest of Asia Pacific: Digital Pathology Market, by End User- Revenue and Forecast to 2028 (USD Million)
Table 37. Organic Developments in the Asia Pacific Digital Pathology Market
Table 38. Inorganic Developments in the Asia Pacific Digital Pathology Market
Table 39. Glossary of Terms, Digital Pathology Market
List of Figures
Figure 1. Asia Pacific Digital Pathology Market Segmentation
Figure 2. Asia Pacific Digital Pathology Market, By Country
Figure 3. Asia Pacific Digital Pathology Market Overview
Figure 4. Scanners Segment Held Largest Share of Product Segment in Asia Pacific Digital Pathology Market
Figure 5. India is Expected to Show Remarkable Growth During the Forecast Period
Figure 6. Asia Pacific: PEST Analysis
Figure 7. Experts Opinion
Figure 8. Impact Analysis of Drivers and Restraints
Figure 9. Asia Pacific Digital Pathology Market - Revenue Forecast and Analysis - 2020- 2028
Figure 1. Asia Pacific Digital Pathology Market, by Product 2022 & 2028 (%)
Figure 1. Asia Pacific Scanners Market Revenue and Forecasts to 2028 (US$ Mn)
Figure 1. Asia Pacific Integrated Market Revenue and Forecasts To 2028 (US$ MN)
Figure 1. Asia Pacific Standalone Market Revenue and Forecasts To 2028 (US$ MN)
Figure 1. Asia Pacific Software Market Revenue and Forecasts to 2028 (US$ Mn)
Figure 1. Asia Pacific Communication System Market Revenue and Forecasts to 2028 (US$ Mn)
Figure 1. Asia Pacific Storage Market Revenue and Forecasts to 2028 (US$ Mn)
Figure 1. Asia Pacific Digital Pathology Market Revenue Share, by Type (2022 and 2028)
Figure 1. Asia Pacific Human Pathology: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
Figure 1. Asia Pacific Veterinary Pathology: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
Figure 20. Asia Pacific Digital Pathology Market, by Application 2022 & 2028 (%)
Figure 21. Asia Pacific Drug Discovery Market Revenue and Forecasts to 2028 (US$ Mn)
Figure 22. Asia Pacific Disease Diagnostics Market Revenue and Forecasts to 2028 (US$ Mn)
Figure 23. Asia Pacific Teleconsultation Market Revenue and Forecasts to 2028 (US$ Mn)
Figure 24. Pacific Training and Education Market Revenue and Forecasts to 2028 (US$ Mn)
Figure 25. Digital Pathology Market Revenue Share, by End User (2022 and 2028)
Figure 26. Asia Pacific Pharma and Biotech Companies: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
Figure 27. Asia Pacific Hospital: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
Figure 28. Asia Pacific Academic: Digital Pathology Market - Revenue and Forecast to 2028 (US$ Million)
Figure 29. Asia Pacific: Digital Pathology Market, by Key Country - Revenue (2022) (USD Million)
Figure 30. Asia Pacific: Digital Pathology Market, by Country, 2022 & 2028 (%)
Figure 31. China: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
Figure 32. Japan: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
Figure 33. India: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
Figure 34. Australia: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
Figure 35. South Korea: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
Figure 36. Rest of Asia Pacific: Digital Pathology Market - Revenue and Forecast to 2028 (USD Million)
Figure 37. Growth Strategies in the Asia Pacific Digital Pathology Market (%)

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Koninklijke Philips N.V.
  • Nikon Corporation
  • Perkin Elmer, Inc.
  • Indica Labs
  • 3Dhistech Ltd.
  • Hamamatsu Photonics K.K.
  • F. Hoffmann-La Roche Ltd
  • Visiopharm A/S
  • Glencoe Software, Inc.
  • Danaher Corporation

Table Information