Pharmaceutical Biotechnology in Drug Development

Table of Contents

1. Introduction to modern concepts in pharmaceutical biotechnology and drug development
2. Pharmacokinetic and pharmacodynamics of biotechnology products
3. Role of biotechnology in amino acids modification
4. Role of biotechnology in nucleic acid modification
5. Monoclonal antibodies: Development, characterization and therapeutic application
6. Development of nanoparticles: recent developments and future prospects
7. Production of biopharmaceuticals from genetically modified organisms
8. Metabolomics as bioanalytical approach for pharmaceutical biotechnology in drug development
9. New biological targets for drug discovery and development
10. Signaling pathways of membrane-spanning receptors for drug discovery and development

Authors

Muhammad Sajid Hamid Akash associate professor and chairman at Department of Pharmaceutical Chemistry, Government College University Faisalabad (GCUF), Pakistan.. Dr. Akash is currently working as associate professor and chairman at Department of Pharmaceutical Chemistry, Government College University Faisalabad (GCUF), Pakistan. He got his bachelor and master's degrees in pharmacy from Bahauddin Zakariya University Multan, Pakistan and PhD degree in Pharmaceutical Analysis from Zhejiang University, China. Currently, he is focusing on investigating the effect of EDCs on various molecular and metabolic pathways that are involved in metabolic disorders and the treatment strategies of these EDCs-induced metabolic disorders funded by Higher Education Commission (HEC) of Pakistan. His Research work is the cutting edge and worthy of extension in developing countries like Pakistan, where it can be most beneficial and cost-effective especially for diabetic patients. Based on his significant scientific contributions in the field of Pharmaceutical Sciences, he has been awarded "Research Productivity Award� from Pakistan Council for Science and Technology (PCST), PAS Gold Medal from Pakistan Academy of Sciences and A.R. Shakoori Gold Medal from Zoological Society of Pakistan. Kanwal Rehman Associate Professor at Department of Pharmacy in The Women University, Multan, Pakistan.. Dr. Kanwal Rehman PhD is working as Associate Professor at Department of Pharmacy in The Women University, Multan, Pakistan. Dr. Kanwal Rehman received her PhD in Pharmacology and Toxicology from Zhejiang University, Hangzhou, China in 2015. She nurtures a keen interest in pathogenesis of metabolic disorders like diabetes mellitus, obesity, and new therapeutic modalities for its treatment. Other work includes detection of environmental pollutants and their cytotoxic effects. She has published about 135 articles. She has also published 50 book chapters with international publishers and 4 books with Springer-Nature. Currently, she is focusing on the investigation of role of pharmacogenomics based upon gene polymorphism on various molecular and metabolic pathways that are involved in mitogenic disorders and treatment strategies like natural biogenic compounds against different risk factors of metabolic disorders including pancreatitis, cardiometabolic disorders and hormonal imbalance. Dr. Kanwal Rehman has also been awarded Research productivity award by Pakistan Council for Science and Technology (PCST), Pakistan. Kanwal Irshad PhD scholar at Department of Pharmaceutical Chemistry in Government College University Faisalabad, Pakistan.. Dr. Kanwal Irshad is working as PhD scholar at Department of Pharmaceutical Chemistry in Government College University Faisalabad, Pakistan. She has done her MPhil from Government College University Faisalabad, Pakistan. She completed her bachelor's (Doctor of Pharmacy) from University of Agriculture, Faisalabad. She has done excellent work on exploring the effect of arsenic on hepatoxicity and nephrotoxicity and their amelioration by bioactive compounds. She has published 5 articles and 8 book chapters with international book publishers. She has received HEC PhD indigenous scholarship for completion of PhD by Higher Education Commission (HEC) of Pakistan. Currently, she is focusing on the investigation of different molecular pathways of arsenic in neurological disorders and their treatment strategies by naturally occurring bioactive compounds. Shuqing Chen Professor, Zhejiang University; Head, Precision Medicine and Biopharmaceuticals Laboratory and Director, International Center for Precision Medicine, Zhejiang-California International NanoSystems Institute, China. Professor Chen was graduated from Zhejiang Medical University in 1983, got his Ph.D. degree in Zhejiang University and had his post-doctor training in Cornell University USA. Professor Chen now is a professor of Zhejiang University, head of the Precision Medicine & Biopharmaceuticals Laboratory, director of International Center for Precision Medicine, Zhejiang-California International NanoSystems Institute, standing committee member of the Division of Pharmacogenomics of the Chinese Pharmacological Society, committee member of the Division of Biochemical and Biotechnological Drugs of the Chinese Pharmaceutical Association, honorary chairman of the Biochemical Drugs Professional Committee of Zhejiang Pharmaceutical Association, director of Zhejiang Bioengineering Society, deputy editor-in-chief of Chinese Journal of Biochemical Pharmacy, editor of Chinese Journal of Pharmaceutical Sciences, international editor of Medical Science Monitor. Dr. Shuqing Chen published 269 articles including Cell, Advanced Materials, Biomaterials, SMALL, Clinical Cancer Research of which 148 are included in SCI/EI. He is the chief editor or editor of 16 books and textbooks. He has presided over five National Natural Science Foundation of China (including two of the State Key Program), two major sub-projects of the National Major Scientific and Technological Special Project for "Significant New Drugs Development�, and one key project of the National Key R & D Plan "Precision Medical Research�. Dr. Shuqing Chen has chaired and accomplished three scientific research, got one Second Prize award and two Third Prize award of Science & Technology Progress of Zhejiang Province.