Chapters are written with the help of authoritative sources of knowledge with the goal of building a foundational understanding of novel drug delivery systems. Since the subject matter is interdisciplinary, it will be of interest to students, teachers and researchers in a broad range of fields, including pharmaceutical sciences, nanotechnology, biomedical engineering and material sciences.
Table of Contents
Chapter 1 Introduction To Nanoparticles And Nanocarriers- Amit Kumar Jain And Neha Gahlot Introduction
- Overview Of Nanoparticles (Nps)
- Structure, Morphology, And Size Analysis
- Optical Characterization
- Physicochemical Properties Of Nanoparticles
- Classification Of Nanoparticles
- Methods Of Synthesis
- Overview On Nanocarriers
- Classification
- Advantages Over Conventional Drug Delivery
- Challenges Faced By These Systems In Nanomedicine
- Applications
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgement
- References
- Sakshi Tiwari, Bina Gidwani, Priya Namdeo, Atul Tripathi, Ravindra Kumar Pandey, Shiv Shankar Shukla, Veenu Joshi, Vishal Jain, Vikas Kumar Jain And Amber Vyas Introduction
- Polymeric Nanoparticles
- Types Of Polymeric Nanoparticles
- Advantages Of Polymeric Nanoparticles
- Disadvantages Of Polymeric Nanoparticles
- Ideal Characteristics Of Polymeric Nanoparticles
- Types Of Polymers Used For Carrier System
- Mechanism Of Drug Release From Polymeric Nanoparticles
- Methods Of Preparation Of Polymeric Nanoparticles
- Pre-Existed Polymer Dispersion Method
- Solvent Evaporation Method
- Salting Out Method
- Supercritical Fluid Technology Method
- Dialysis Method
- Nanoprecipitation Method
- Monomer Polymerization Method
- Emulsion Polymerization Method
- Interfacial Polymerization Method
- Controlled Radical Polymerization Method
- Applications Of Polymeric Nanoparticles
- Cancer Imaging And Diagnosis
- Cancer Treatment
- Ocular Drug Delivery
- Vaginal Disease Treatment
- Central Nervous System (Cns) Drug Deliver
- Cardiovascular Disorders
- Bacterial And Viral Infections
- Antidotes
- Nutraceutical Agents
- Food Packaging
- Patents On Polymeric Nanoparticles
- Conclusion
- Future Prospects
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Balaga Venkata Krishna Rao, Aditi Pradhan, Sneha Singh And Abhimanyu Dev Introduction
- Specific & Targeted Nanoparticles
- Polymer-Based Nanoparticles
- Micelles
- Drug Conjugates
- Nanogels
- Dendrimers
- Nanoparticles
- Non-Polymer Based Nanoparticles
- Carbon Dots
- Carbon Nanotubes
- Quantum Dots
- Silica-Based Nanoparticles
- Nanodiamonds
- Metallic Nanoparticles
- Lipid-Based Nanoparticles
- Liposomes
- Exosomes
- Solid-Lipid Nanoparticles (Sln)
- Drug Nanocrystals
- Applications Of Targeted Therapeutic Nanoparticles
- Autoimmne And Immunodeficient Disorders
- Cardiovascular Disease
- Infectious Diseases
- Cancer
- Pulmonary Diseases
- Challenges In Nanoparticulate Drug Delivery Systems
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgement
- References
- Bina Gidwani, Varsha Sahu, Priya Namdeo, Sakshi Tiwari, Atul Tripathi, Ravindra Kumar Pandey, Shiv Shankar Shukla, Veenu Joshi, Vishal Jain, Suresh Thareja And Amber Vyas Introduction
- Importance Of Targeted Drug Delivery
- Advantages Of Nanocarriers In Drug Targeting
- Mechanism Of Drug Targeting
- Active Targeting
- First-Order Targeting/ Organ Targeting
- Second-Order Targeting/Cell Targeting
- Third-Order Targeting/ Intracellular Targeting
- Passive Targeting
- Inverse Targeting
- Physical Targeting
- Dual Targeting
- Double Targeting
- Types Of Nanocarriers For Targeting
- Lipid-Based Nanocarriers
- Polymer-Based Nanocarriers
- Non-Polymers-Based Nanocarriers
- Liposome
- Solid Lipid Nanoparticles (Slns)
- Polymeric Nanoparticles (Pnps)
- Dendrimer
- Nanoemulsion
- Quantum Dots
- Mesoporous Silica Nanoparticles
- Polymeric Micelles
- Strategies For Drug Loading In Nanocarriers Or Their Release
- Marketed Formulations, Patents, And Recent Developments
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Ashish K. Parashar, Preeti Patel, Monika Kaurav, Krishna Yadav, Dilpreet Singh, G.D. Gupta And Balak Das Kurmi Introduction
- Concept Of Nanotheranostics
- Nanomaterials As Nanotheranostics
- Types Of Nanotheranostic Systems
- Theranostic Quantum Dots
- Metallic Nanomaterials For Theranostics
- Superparamagnetic Iron Oxide Nps(Spions)
- Gold Nps As Nanotheranostic Carrier
- Carbon-Based Nanomaterials For Theranostics
- Graphene Oxide As Nanotheranostics
- Polymer-Based Theranostics Nanomaterials
- Theranostic Liposomes
- Theranostic Carbon Nanotube (Cnt)
- Polymeric Micelle Nps As Nanotheranostic
- Theranostic Dendrimers
- Polymer Conjugates
- Therapeutic Applications Of Nanotheranostics
- Applications Of Nanotheranostics In Therapy
- Photodynamic Therapy
- Photothermal Therapy
- Hyperthermia Treatment
- Applications Of Nanotheranostics For Imaging
- Optical Imaging
- Mri Imaging
- Ultrasound Imaging
- Nanotheranostics In Cancer Treatment
- Nanotheranostics For Photothermal And Photodynamic Cancer Therapy
- Engineered Mammalian Cell-Based Theranostic Agents For Cancer Therapy
- Theranostic Nanomedicine In Cardiovascular Diseases (Cvd)
- Nanotheranostics For The Imaging Of Pulmonary Diseases
- Theranostics For Treatment Of Diseases Of The Central Nervous System
- Theranostics For Treatment Of Autoimmune Diseases
- Conclusion
- Future Prospects
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Sunil K. Jain, Kuldeep Rajpoot, K. Kesavan, Awesh Yadav, Umesh Gupta And Prem N. Gupta Introduction
- Nano Approaches
- Mucoadhesion Approach
- Ph Responsive Nanoparticles
- Receptor Mediated Targeting
- Liposomes
- Nanolipobeads, Polymeric Nano-Micelles And Nanogels
- Herbal Approach
- Nanoparticulate Vaccine
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgement
- References
- Kuldeep Rajpoot, Sunil K. Jain And Saroj Dangi Rajpoot Introduction
- Physiological Aspects Of Stomach
- Factors Influencing The Activity Of Grncs In The Stomach
- Physiological Factors
Author
- Akhlesh K. Jain
- Keerti Mishra