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Nanoparticles and Nanocarriers Based Pharmaceutical Formulations

  • Book

  • December 2022
  • Bentham Science Publishers Ltd
  • ID: 5716686
Nanomedicine is a rapidly expanding field because of its benefits over conventional drug delivery technology, as it offers site-specific and target-oriented delivery of therapeutic agents. Nanoparticles and Nanocarriers Based Pharmaceutical Preparations presents a structured summary of recent advances and discoveries in nanomedicine and nanocarrier-based drug delivery. The book covers several key topics in a very simple and easy to understand language. Readers will be familiarized with many types of nanocarriers that have been developed over the past decade, the pharmaceutical formulations composed of organic and inorganic materials as well as their clinical benefits.

Chapters are written with the help of authoritative sources of knowledge with the goal of building a foundational understanding of novel drug delivery systems. Since the subject matter is interdisciplinary, it will be of interest to students, teachers and researchers in a broad range of fields, including pharmaceutical sciences, nanotechnology, biomedical engineering and material sciences.

Table of Contents

Chapter 1 Introduction To Nanoparticles And Nanocarriers
  • Amit Kumar Jain And Neha Gahlot Introduction
  • Overview Of Nanoparticles (Nps)
  • Structure, Morphology, And Size Analysis
  • Optical Characterization
  • Physicochemical Properties Of Nanoparticles
  • Classification Of Nanoparticles
  • Methods Of Synthesis
  • Overview On Nanocarriers
  • Classification
  • Advantages Over Conventional Drug Delivery
  • Challenges Faced By These Systems In Nanomedicine
  • Applications
  • Conclusion
  • Consent For Publication
  • Conflict Of Interest
  • Acknowledgement
  • References
Chapter 2 Polymeric Nanoparticles As Drug Delivery System: Basic Concepts And Applications
  • Sakshi Tiwari, Bina Gidwani, Priya Namdeo, Atul Tripathi, Ravindra Kumar Pandey, Shiv Shankar Shukla, Veenu Joshi, Vishal Jain, Vikas Kumar Jain And Amber Vyas Introduction
  • Polymeric Nanoparticles
  • Types Of Polymeric Nanoparticles
  • Advantages Of Polymeric Nanoparticles
  • Disadvantages Of Polymeric Nanoparticles
  • Ideal Characteristics Of Polymeric Nanoparticles
  • Types Of Polymers Used For Carrier System
  • Mechanism Of Drug Release From Polymeric Nanoparticles
  • Methods Of Preparation Of Polymeric Nanoparticles
  • Pre-Existed Polymer Dispersion Method
  • Solvent Evaporation Method
  • Salting Out Method
  • Supercritical Fluid Technology Method
  • Dialysis Method
  • Nanoprecipitation Method
  • Monomer Polymerization Method
  • Emulsion Polymerization Method
  • Interfacial Polymerization Method
  • Controlled Radical Polymerization Method
  • Applications Of Polymeric Nanoparticles
  • Cancer Imaging And Diagnosis
  • Cancer Treatment
  • Ocular Drug Delivery
  • Vaginal Disease Treatment
  • Central Nervous System (Cns) Drug Deliver
  • Cardiovascular Disorders
  • Bacterial And Viral Infections
  • Antidotes
  • Nutraceutical Agents
  • Food Packaging
  • Patents On Polymeric Nanoparticles
  • Conclusion
  • Future Prospects
  • Consent For Publication
  • Conflict Of Interest
  • Acknowledgements
  • References
Chapter 3 An Overview On Nanoparticulate Drug Delivery System For Its Specific And Targeted Effects In Various Diseases
  • Balaga Venkata Krishna Rao, Aditi Pradhan, Sneha Singh And Abhimanyu Dev Introduction
  • Specific & Targeted Nanoparticles
  • Polymer-Based Nanoparticles
  • Micelles
  • Drug Conjugates
  • Nanogels
  • Dendrimers
  • Nanoparticles
  • Non-Polymer Based Nanoparticles
  • Carbon Dots
  • Carbon Nanotubes
  • Quantum Dots
  • Silica-Based Nanoparticles
  • Nanodiamonds
  • Metallic Nanoparticles
  • Lipid-Based Nanoparticles
  • Liposomes
  • Exosomes
  • Solid-Lipid Nanoparticles (Sln)
  • Drug Nanocrystals
  • Applications Of Targeted Therapeutic Nanoparticles
  • Autoimmne And Immunodeficient Disorders
  • Cardiovascular Disease
  • Infectious Diseases
  • Cancer
  • Pulmonary Diseases
  • Challenges In Nanoparticulate Drug Delivery Systems
  • Conclusion
  • Consent For Publication
  • Conflict Of Interest
  • Acknowledgement
  • References
  • Bina Gidwani, Varsha Sahu, Priya Namdeo, Sakshi Tiwari, Atul Tripathi, Ravindra Kumar Pandey, Shiv Shankar Shukla, Veenu Joshi, Vishal Jain, Suresh Thareja And Amber Vyas Introduction
  • Importance Of Targeted Drug Delivery
  • Advantages Of Nanocarriers In Drug Targeting
  • Mechanism Of Drug Targeting
  • Active Targeting
  • First-Order Targeting/ Organ Targeting
  • Second-Order Targeting/Cell Targeting
  • Third-Order Targeting/ Intracellular Targeting
  • Passive Targeting
  • Inverse Targeting
  • Physical Targeting
  • Dual Targeting
  • Double Targeting
  • Types Of Nanocarriers For Targeting
  • Lipid-Based Nanocarriers
  • Polymer-Based Nanocarriers
  • Non-Polymers-Based Nanocarriers
  • Liposome
  • Solid Lipid Nanoparticles (Slns)
  • Polymeric Nanoparticles (Pnps)
  • Dendrimer
  • Nanoemulsion
  • Quantum Dots
  • Mesoporous Silica Nanoparticles
  • Polymeric Micelles
  • Strategies For Drug Loading In Nanocarriers Or Their Release
  • Marketed Formulations, Patents, And Recent Developments
  • Conclusion
  • Consent For Publication
  • Conflict Of Interest
  • Acknowledgements
  • References
Chapter 5 Nanomaterials As Diagnostic Tools And Drug Carriers
  • Ashish K. Parashar, Preeti Patel, Monika Kaurav, Krishna Yadav, Dilpreet Singh, G.D. Gupta And Balak Das Kurmi Introduction
  • Concept Of Nanotheranostics
  • Nanomaterials As Nanotheranostics
  • Types Of Nanotheranostic Systems
  • Theranostic Quantum Dots
  • Metallic Nanomaterials For Theranostics
  • Superparamagnetic Iron Oxide Nps(Spions)
  • Gold Nps As Nanotheranostic Carrier
  • Carbon-Based Nanomaterials For Theranostics
  • Graphene Oxide As Nanotheranostics
  • Polymer-Based Theranostics Nanomaterials
  • Theranostic Liposomes
Chapter 4 Nanocarriers For Drug Targeting
  • Theranostic Carbon Nanotube (Cnt)
  • Polymeric Micelle Nps As Nanotheranostic
  • Theranostic Dendrimers
  • Polymer Conjugates
  • Therapeutic Applications Of Nanotheranostics
  • Applications Of Nanotheranostics In Therapy
  • Photodynamic Therapy
  • Photothermal Therapy
  • Hyperthermia Treatment
  • Applications Of Nanotheranostics For Imaging
  • Optical Imaging
  • Mri Imaging
  • Ultrasound Imaging
  • Nanotheranostics In Cancer Treatment
  • Nanotheranostics For Photothermal And Photodynamic Cancer Therapy
  • Engineered Mammalian Cell-Based Theranostic Agents For Cancer Therapy
  • Theranostic Nanomedicine In Cardiovascular Diseases (Cvd)
  • Nanotheranostics For The Imaging Of Pulmonary Diseases
  • Theranostics For Treatment Of Diseases Of The Central Nervous System
  • Theranostics For Treatment Of Autoimmune Diseases
  • Conclusion
  • Future Prospects
  • Consent For Publication
  • Conflict Of Interest
  • Acknowledgements
  • References
Chapter 6 Targeting Potential Of Nanocarriers For Efficient Treatment Of H. Pylori Infection
  • Sunil K. Jain, Kuldeep Rajpoot, K. Kesavan, Awesh Yadav, Umesh Gupta And Prem N. Gupta Introduction
  • Nano Approaches
  • Mucoadhesion Approach
  • Ph Responsive Nanoparticles
  • Receptor Mediated Targeting
  • Liposomes
  • Nanolipobeads, Polymeric Nano-Micelles And Nanogels
  • Herbal Approach
  • Nanoparticulate Vaccine
  • Conclusion
  • Consent For Publication
  • Conflict Of Interest
  • Acknowledgement
  • References
Chapter 7 Gastro-Retentive Nanocarriers In Drug Delivery
  • Kuldeep Rajpoot, Sunil K. Jain And Saroj Dangi Rajpoot Introduction
  • Physiological Aspects Of Stomach
  • Factors Influencing The Activity Of Grncs In The Stomach
  • Physiological Factors

Author

  • Akhlesh K. Jain
  • Keerti Mishra