Long-Acting Drug Delivery Technologies and Services Market Industry Trends and Global Forecasts to 2035, by Compatible Dosage Form, Principle, Strategy, Type of Molecule Delivered, Type of Material Used, and Key Geographical Regions

The global long-acting drug delivery technologies and services market is estimated to grow from USD 1.06 billion in the current year to USD 4.62 billion by 2035, at a CAGR of 13.1% during the forecast period to 2035.

Long-Acting Drug Delivery Technologies and Services Market: Growth and Trends

Long-acting drug delivery systems are being widely adopted for sustained delivery of pharmaceutical drugs to treat a plethora of disease indications, including neurological diseases, infectious diseases, pulmonary diseases, ophthalmological diseases and opioid use disorders. These systems enable effective administration and improved efficacy of peptides, antibodies and vaccines. These novel delivery systems also enable the effective administration of macromolecules for a long-term effect, which are otherwise difficult to administer. Given the potential of long-acting drug delivery systems to improve patient compliance and adherence to medication, industry players have undertaken numerous initiatives to enable the clinical and commercial translation of long-acting drugs under development. This has led to the development of drugs that exhibit prolonged effects (for a few months or years). The application of long-acting therapeutics has the potential to benefit not only the patients but also the healthcare system. In particular, these formulations are beneficial to treat women living in low / middle income countries, as it will result in a substantial drop in the anticipated clinic visits and associated costs.

Furthermore, owing to the formulation and developmental challenges associated with complex dosage forms, the reliability of stakeholders having expertise in the long-acting drug delivery field has grown significantly. This will eventually aid drug developers to address bottlenecks stemming from conventional treatment options and improve the overall clinical outcome. Driven by the technological advancements in the field and rising demand for long-acting drugs, the long-acting drug delivery technologies and services market is anticipated to witness notable growth in the foreseen future.

Long-Acting Drug Delivery Technologies and Services Market: Key Insights

The report delves into the current state of the long-acting drug delivery technologies and services market and identifies potential growth opportunities within the industry.

Some key findings from the report include:

• At present, more than 100 long-acting drug delivery technologies are being offered by companies across the globe in order to develop long-acting drugs for a myriad of disease indications.

• Nearly 90% of the technologies are based on manipulation of drug release profile; majority of these technologies can support the development of long-acting injectables with dosing intervals of at least a month.
• In pursuit of gaining a competitive edge, industry stakeholders are actively innovating and developing novel long-acting drug delivery technologies that can be utilized across multiple therapeutic areas.
• The current service providers landscape features the presence of over 40 companies, offering a wide range of development and manufacturing services for the long-acting delivery of drugs.
• The market is fragmented, featuring the presence of both established players and small firms that have the expertise to develop / manufacture long-acting drugs / delivery systems for various dosage forms.
• The growing interest in this domain is clearly evident from the rise in partnership activity; in fact, more than 60 collaborations related to long-acting drug delivery were inked in the last three years.
• ~575 scientific articles published recently signify the focused efforts being led by researchers to identify and develop novel long-acting technologies and therapeutic interventions.
• Over 1,200 patents related to long-acting drug delivery have been filed / granted by various stakeholders in order to protect the intellectual property generated within this field.
• 400+ grants have been awarded for the ongoing R&D efforts for long-acting drug delivery; University of North Carolina and John Hopkins University have emerged as the most popular recipient organizations.
• The market opportunity associated with long-acting drug delivery technologies is anticipated to witness an annualized growth of nearly 13% over the next decade.

Long-Acting Drug Delivery Technologies and Services Market: Key Segments

Manipulation of Drug Release from Delivery Systems Occupy the Largest Share of the Long-Acting Drug Delivery Technologies and Services Market

Based on the principle, the market is segmented into manipulation of drug release from delivery systems and manipulation of in vivo clearance. At present, manipulation of drug release from delivery systems segment holds the maximum share of the long-acting drug delivery technologies and services market. This trend is unlikely to change in the near future.

Micro-Encapsulation is Likely to Dominate the Long-Acting Drug Delivery Technologies and Services Market During the Forecast Period

Based on the strategy, the market is segmented into chemical modification, micro-encapsulation, long-acting hydrogels, long acting implants, long acting microneedles, multivesicular liposomes, nanocrystal suspensions and protein fusion. Currently, micro-encapsulation holds the maximum share of the long-acting drug delivery technologies and services market. This trend is unlikely to change in the near future. Further, the long-acting drug delivery technologies and services market for long-acting microneedles is likely to grow at a relatively higher CAGR.

Long Acting Injectables Occupy the Largest Share of the Long-Acting Drug Delivery Technologies and Services Market

Based on the compatible dosage form, the market is segmented into long acting injectables, long acting implantable, long-acting orals, long acting topicals / transdermals and other dosage forms. At present, long-acting injectables captures the highest share of the long-acting drug delivery technologies and services market. It is worth highlighting that long-acting drug delivery technologies and services market for implantable is likely to grow at relatively higher CAGR.

Small Molecules are the Fastest Growing Segment of the Long-Acting Drug Delivery Technologies and Services Market During the Forecast Period

Based on the type of molecules delivered, the market is segmented into small molecules, biologics and other molecules. It is worth highlighting that, currently, small molecules hold a larger portion of the long-acting drug delivery technologies and services market. This trend is likely to remain the same in the coming decade.

Polymer based Materials are likely to Dominate the Long-Acting Drug Delivery Technologies and Services Market During the Forecast Period

Based on the type of material used, the market is segmented into polymer-based materials and non-polymer based materials. It is worth highlighting that majority of the current long-acting drug delivery technologies and services market is captured by the polymer-based materials.

North America Accounts for the Largest Share of the Market

Based on key geographical regions, the market is segmented into North America, Europe, Asia-Pacific, and Middle East and North Africa. The majority of the share is expected to be captured by players based in North America and Europe. It is worth highlighting that, over the years, the market in Europe is expected to grow at a higher CAGR.

The market sizing and opportunity analysis has been segmented across the following parameters:

Principle 

• Manipulation of drug release from delivery systems
• Manipulation of in vivo clearance 

Strategy 

• Chemical Modification
• Micro-encapsulation
• Long-Acting Hydrogels
• Long-Acting Implants
• Long-Acting Microneedles
• Multivesicular Liposomes
• Nanocrystal Suspensions
• Protein Fusion

Compatible Dosage Form

• Long-Acting Injectables
• Long-Acting Implantables
• Long-Acting Oral,
• Topical / Transdermal
• Vaginal
• Other Dosage Forms

Type of Molecule Delivered

• Small Molecules
• Biologics
• Other Molecules

Type of Material Used 

• Polymer based
• Non-polymer based

Key Geographical Regions

• North America
• Europe
• Asia-Pacific
• Middle East and North Africa

Key Players in the Long-Acting Drug Delivery Technologies and Services Market, Profiled in the Report Include:

• Adare Pharma Solutions
• AMW
• Bostal Drug Delivery
• Creative Biolabs
• ForDoz Pharma
• Innocore Pharmaceuticals
• Integral BioSystems
• LATITUDE Pharmaceuticals
• Navin Saxena Research and Technology Centre (NSRT)
• Samyang Biopharm

Long-Acting Drug Delivery Technologies and Services Market: Research Coverage

• Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the long-acting drug delivery technologies and services market, focusing on key market segments, including principle, strategy, compatible dosage form, type of molecule delivered, type of material used and key geographical regions.
• Market Landscape 1: A comprehensive evaluation of long-acting drug delivery technologies, considering various parameters, such as principle, strategy, type of material used, compatible dosage form(s), extended dosing interval(s), type of molecule(s) delivered, highest phase of development, number of approved drugs and therapeutic area(s). Additionally, the chapter includes information on various technology developers, along with analysis based on multiple parameters, such as their year of establishment, company size, location of headquarters and most active players (in terms of number of technologies developed).
• Market Landscape 2: A comprehensive evaluation of contract service providers engaged in the long-acting drug delivery technologies and services market, considering various parameters, such as year of establishment, company size (in terms of number of employees), location of headquarters, location of facilities, type of service provider(s), scale of operation, compatible dosage form(s), service(s) offered and type of molecule(s) supported.
• Technology Competitiveness Analysis: A comprehensive competitive analysis of long-acting drugs delivery technologies, examining factors, such as developer power and technology strength.
• Company Competitiveness Analysis: A comprehensive competitive analysis of long-acting drugs delivery service providers, examining factors, such as company strength and service strength.
• Company Profiles: In-depth profiles of key industry players offering technologies and offering services in the field of long-acting drugs delivery, focusing on company overviews, technology portfolio, service portfolio, recent developments and an informed future outlook.
• Partnerships and Collaborations: An analysis of partnerships established in this sector, since 2018, covering acquisitions, manufacturing agreements, product development and commercialization agreements, service alliance, technology licensing agreements, and other relevant agreements.
• Publication Analysis: A detailed analysis of over 570 peer-reviewed, scientific articles focused on research related to long acting drugs delivery, based on several relevant parameters, such as year of publication, type of publication, popular keywords, top journals, top publishers, top copyright holders and key funding institutes (in terms of number of articles published).
• Patent Analysis: Detailed analysis of various patents filed / granted related to long-acting drug delivery based on publication year, geographical region, CPC symbols, leading players (in terms of number of patents filled / granted) and type of organization. It also includes a patent benchmarking analysis and a detailed valuation analysis.
• Grant Analysis: A comprehensive evaluation of various grants that have been awarded to research institutes engaged in conducting research related to long-acting drug delivery, since 2018, based on various important parameters, such as year of grant award, amount awarded, support period, type of funding institute center, type of grant application, purpose of grant award, activity code, NIH spending category, study section involved, popular NIH departments (in terms of number of grants), type of recipient organization, prominent program officers (in terms of number of grants) and popular recipient organizations (in terms of number of grants and amount awarded).

Key Questions Answered in this Report

• How many companies are currently engaged in this market?
• Which are the leading companies in this market?
• What kind of partnership models are commonly adopted by industry stakeholders?
• What factors are likely to influence the evolution of this market?
• What is the current and future market size?
• What is the CAGR of this market?
• How is the current and future market opportunity likely to be distributed across key market segments?

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• The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
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