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Dupuytren's Disease. A Scientific Review

  • Book

  • June 2023
  • Elsevier Health Science
  • ID: 5755393
Dupuytren's Disease: A Scientific Review offers consolidated, up-to-date coverage of both the basic normal (nonpathologic) science and cutting-edge science of this progressive disorder. Drs. Lawrence C. Hurst, Marie A. Badalamente, and David Edward Komatsu break down the complex topic of Dupuytren’s contracture into its basic scientific components. Hand surgeons, plastic surgeons, and orthopaedic surgeons will find this unique, concise title to be especially helpful in their practices.- Includes chapters on prevalence of Dupuytren's disease, normal genetics and the genetic abnormalities associated with Dupuytren's disease, and collagen and collagen synthesis in healthy fascia and Dupuytren's disease- Provides numerous illustrations throughout- Contains an in-depth bibliography and a useful, complete glossary of related terms- Consolidates today's available information on Dupuytren’s science into a single, convenient resource

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Table of Contents

1. Incidence and prevalence of Dupuytren’s disease
2. Epidemiology and risk factors in Dupuytren's disease
3. Anatomy and pathoanatomy in Dupuytren's disease
4. Genetics of Dupuytren’s disease
5. Cells of Dupuytren’s disease
6. Growth factors, hormones, cytokines, and free radicals in Dupuytren’s disease
7. MicroRNAs in Dupuytren's disease
8. Signaling pathways in Dupuytren’s disease
9. Collagen and collagen synthesis in Dupuytren’s disease
10. Collagenase
11. Extracellular matrix in Dupuytren’s disease
12. Developing new therapeutics for Dupuytren’s disease

Authors

Lawrence C. Hurst Professor and Vice Chairman, Department of Orthopaedics, USA. Marie A. Badalamente Dept. Orthopaedics, Health Science Center State University, USA. David Edward Komatsu