Surgical Sealants & Adhesives Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2020-2030F

The Surgical Sealants & Adhesives Market was valued at USD 2.41 Billion in 2024, and is expected to reach USD 3.87 Billion by 2030, rising at a CAGR of 8.31%.

The global surgical sealants and adhesives market is witnessing significant growth, driven by their critical role in modern surgical procedures across cardiovascular, cosmetic, orthopedic, and general surgery applications. These products, including fibrin sealants, cyanoacrylates, and hydrogels, facilitate wound closure, reduce postoperative complications, and enhance patient recovery by minimizing blood loss and infection risks.

The market is propelled by the rising prevalence of chronic diseases, such as cardiovascular disorders and cancer, which increase surgical interventions globally. The World Health Organization estimates millions of surgeries performed annually, underscoring the need for effective sealing solutions. Additionally, the shift toward minimally invasive procedures, supported by policies like the U.S. Affordable Care Act, boosts demand for advanced sealants that offer rapid healing and reduced scarring.

The market is further driven by growing healthcare expenditure in emerging economies and the aging population, which is more prone to surgical interventions. Regulatory frameworks, such as the FDA’s approval processes and the EU’s Medical Device Regulation, encourage the development of biocompatible and bioresorbable sealants, aligning with patient safety goals. The cosmetics industry increasingly adopts these products for scar-free outcomes, while cardiovascular surgeries leverage them for hemostasis. Despite challenges like high costs and regulatory hurdles, innovations in bio-based and synthetic formulations enhance market potential. The forecast period of 2020-2030F is expected to see sustained growth as manufacturers focus on patient-centric solutions and healthcare systems prioritize efficient surgical outcomes.

Key Market Drivers

Rising Prevalence of Chronic Diseases and Surgical Procedures

The global surgical sealants and adhesives market is significantly driven by the rising prevalence of chronic diseases, including cardiovascular disorders, cancer, and diabetes, which necessitate frequent surgical interventions. According to the World Health Organization (WHO), more than 310 million major surgical procedures are performed annually worldwide, reflecting the growing burden of chronic conditions. The Centers for Disease Control and Prevention (CDC) reports over 1.9 million new cancer cases annually in the U.S. (2023), many requiring surgical management. Similarly, the World Heart Federation estimates that cardiovascular diseases account for over 20.5 million deaths annually (2023), with millions of patients undergoing bypass, valve repair, and transplant surgeries.

Policies promoting early detection and treatment, such as the EU’s Cancer Mission targeting 3 million lives saved by 2030, further increase surgical volumes and drive demand for effective sealants to manage tissue closure and bleeding. Manufacturers are innovating with fibrin and cyanoacrylate-based sealants that offer rapid hemostasis and biocompatibility for complex surgeries. In India, government programs like Ayushman Bharat, which aims to provide healthcare coverage to over 500 million citizens, enhance access to surgical care, boosting market adoption. This trend is expected to accelerate through 2030, with chronic disease prevalence and surgical needs expanding worldwide.

Key Market Challenges

High Costs of Advanced Sealants and Adhesives

The high cost of advanced surgical sealants and adhesives poses a significant challenge, particularly in cost-sensitive regions like Asia-Pacific and the Middle East & Africa. Developing bioresorbable and biocompatible formulations requires substantial R&D investments, increasing product prices. This limits adoption in low-income healthcare systems, where traditional sutures remain prevalent.

Smaller hospitals and clinics struggle to afford these products, hindering market penetration. The need for clinical trials to meet regulatory standards, such as FDA and EMA requirements, further escalates costs. Addressing this challenge requires cost-effective production and reimbursement policies, but economic constraints pose barriers. The industry must navigate these cost issues to ensure broader adoption through 2030.

Key Market Trends

Development of Bio-Based and Bioresorbable Sealants

The development of bio-based and bioresorbable surgical sealants is a key trend, driven by demand for biocompatible solutions that reduce postoperative complications. Manufacturers like Baxter are focusing on fibrin and collagen-based sealants that degrade naturally, aligning with policies like the EU’s Green Deal. This trend is prominent in North America, where hospitals prioritize patient safety.

These sealants improve outcomes in cardiovascular and cosmetic surgeries, reducing infection risks. Reports highlight increased R&D investments in bio-based materials, enhancing tissue regeneration. This trend is expected to drive growth through 2030, as sustainability and patient-centric care gain traction.

Key Market Players

• Tricol Biomedical, Inc.
• Baxter International, Inc.
• Johnson & Johnson
• Becton, Dickinson and Company
• CryoLife, Inc.
• Cardinal Health, Inc.
• B. Braun Melsungen AG
• Integra Lifesciences Holdings Corporation
• Medline Industries, Inc.
• Adhezion Biomedical, LLC

Report Scope:

In this report, global surgical sealants & adhesives market has been segmented into following categories, in addition to the industry trends which have also been detailed below:

Surgical Sealants & Adhesives Market, by type:

• Natural/Biological
• Fibrin Sealants
• Collagen Based Adhesives
• Gelatin Based Adhesives
• Synthetic/Semi-Synthetic
• Cyanoacrylates
• Polymeric Hydrogels
• Urethane Based Adhesives

Surgical Sealants & Adhesives Market, By Indication:

• Tissue Sealing
• Surgical Hemostasis
• Tissue Engineering

Surgical Sealants & Adhesives Market, By Application:

• Cardiovascular Surgery
• General Surgery
• CNS Surgery
• Orthopedic Surgery
• Cosmetic Surgery
• Others

Surgical Sealants & Adhesives Market, By Region:

• North America
• United States
• Canada
• Mexico
• Asia-Pacific
• China
• India
• South Korea
• Australia
• Japan
• Europe & CIS
• Germany
• France
• United Kingdom
• Spain
• Italy
• South America
• Brazil
• Argentina
• Colombia
• Middle East & Africa
• South Africa
• Saudi Arabia
• UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in global Surgical Sealants & Adhesives market.

Available Customizations:

With the given market data, the publisher offers customizations according to a company’s specific needs. The following customization options are available for the report.

Company Information

• Detailed analysis and profiling of additional market players (up to five).

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