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Menopausal Hot Flashes Treatment Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2020-2031F

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  • 188 Pages
  • July 2025
  • Region: Global
  • TechSci Research
  • ID: 5778560
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The Menopausal Hot Flashes Treatment Market was valued at USD 6.45 Billion in 2024, and is expected to reach USD 8.79 Billion by 2030, rising at a CAGR of 5.43%. The global menopausal hot flashes treatment market is evolving rapidly, driven by growing awareness of women's health issues and increasing demand for effective symptom management during menopause. As more women seek relief from the discomfort and disruption caused by hot flashes, the market is witnessing the introduction of a diverse range of treatment options. These include hormone replacement therapies, non-hormonal pharmaceuticals, herbal remedies, and lifestyle-oriented solutions such as dietary supplements and wellness programs.

Pharmaceutical companies are continuously investing in research and development to formulate therapies that are both effective and carry fewer side effects. For example, a December 2023 article in the Journal of the Menopause Society reported findings from an online study involving 12,268 postmenopausal women across countries like Brazil, Canada, Mexico, and several Nordic nations. It revealed that around 15.6% experienced moderate to severe vasomotor symptoms (VMS). This widespread prevalence is anticipated to fuel market growth in the coming years. Hormone-based treatments remain widely used due to their proven efficacy, but concerns around long-term safety have led to a rising interest in non-hormonal alternatives.

These alternatives are particularly appealing to women who are unable or unwilling to undergo hormone therapy, fueling innovation in selective serotonin reuptake inhibitors, plant-based treatments, and wearable cooling technologies. In addition to traditional treatment avenues, there is a notable shift toward personalized care and holistic wellness approaches. Healthcare providers are increasingly adopting integrated treatment plans that consider not only physical symptoms but also the emotional and psychological aspects of menopause. Telemedicine platforms and digital health tools are also playing a growing role in patient engagement, enabling better management and follow-up care.

The market is also being shaped by demographic and social changes, such as the growing population of aging women and the destigmatization of menopause in many regions. This cultural shift is empowering more women to seek professional medical help and demand high-quality treatments. As a result, the market is poised for continued growth, with opportunities emerging for both established players and new entrants offering innovative therapies that cater to the diverse and changing needs of menopausal women across the globe.

Key Market Drivers

Rising Awareness of Menopause-Related Health Issues

Rising awareness of menopause-related health issues has become a pivotal force driving the global menopausal hot flashes treatment market. For many years, menopause was considered a private or even taboo topic, leading to limited discussion and a lack of proactive medical engagement. However, in recent years, societal attitudes have shifted significantly.

Health organizations, advocacy groups, and media platforms are increasingly highlighting the challenges women face during menopause, especially the disruptive symptoms such as hot flashes, night sweats, and sleep disturbances. This growing visibility has empowered women to seek medical advice and explore available treatment options more confidently. For example, in May 2023, the U.S. Food and Drug Administration approved Veozah (fezolinetant), an oral treatment for moderate to severe vasomotor symptoms, commonly known as hot flashes, associated with menopause. The introduction of such innovative therapies is likely to enhance access to menopausal treatments and support market growth in the coming years.

Educational initiatives and awareness campaigns are playing a critical role in informing women about the physiological changes associated with menopause and the importance of timely intervention. These efforts are not only helping women recognize symptoms earlier but also encouraging open dialogue with healthcare providers. As a result, there is a notable increase in consultations related to menopause management, leading to greater demand for both pharmaceutical and non-pharmaceutical solutions.

Healthcare professionals are also becoming more proactive in addressing menopausal symptoms during routine check-ups, further normalizing the conversation around menopause. At the same time, the digital era has enabled access to a vast pool of information, forums, and telemedicine services, making it easier for women to educate themselves and connect with specialists from the comfort of their homes.

The increased focus on women's health across global health agendas is also pushing policymakers and healthcare providers to prioritize menopause management. This has led to the development of specialized clinics, wellness programs, and tailored treatment regimens, all aimed at improving quality of life during this transition. In turn, this heightened awareness is translating into a larger, more engaged consumer base actively seeking effective solutions for hot flashes, thereby propelling the growth of the menopausal hot flashes treatment market.

Key Market Challenges

Safety Concerns Around Hormone Therapy

Safety concerns around hormone therapy remain one of the most significant challenges in the global menopausal hot flashes treatment market. While Hormone Replacement Therapy (HRT) has long been considered the most effective option for alleviating hot flashes and other vasomotor symptoms associated with menopause, its potential risks have created a climate of caution among both patients and healthcare providers. Studies linking long-term hormone use - particularly estrogen-progestin combinations - to increased risks of breast cancer, blood clots, stroke, and cardiovascular events have led to heightened scrutiny of HRT prescriptions.

These safety concerns have prompted regulatory authorities to issue strict guidelines on the use of hormone therapy, recommending the lowest effective dose for the shortest possible duration. As a result, many women and clinicians are either reluctant to initiate or continue HRT, particularly in cases where the patient has a personal or family history of hormone-sensitive conditions. This has limited the therapy’s appeal, despite its proven efficacy, and has created a significant demand for safer, non-hormonal alternatives. Moreover, the fear surrounding hormone therapy has contributed to misinformation and confusion, causing some women to avoid treatment altogether even when they might benefit from it. This underscores the need for clearer patient education and better risk-benefit communication by healthcare professionals.

These ongoing safety concerns are reshaping the treatment landscape, pushing pharmaceutical companies to innovate and develop non-hormonal therapies with better safety profiles. Addressing these concerns effectively is crucial for expanding patient access and building trust in the evolving options available for managing menopausal hot flashes.

Key Market Trends

Growing Preference for Non-Hormonal Therapies

The growing preference for non-hormonal therapies is emerging as a defining trend in the global menopausal hot flashes treatment market. Historically, hormone replacement therapy (HRT) has been the most widely used and effective option for managing vasomotor symptoms like hot flashes. However, concerns surrounding the long-term safety of HRT - including increased risks of breast cancer, stroke, and cardiovascular conditions - have led many women to seek alternative treatments. This shift in preference has opened the door for the development and adoption of non-hormonal therapies that offer relief without the potential complications associated with hormones.

Non-hormonal treatments encompass a wide range of options, including selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), gabapentin, and clonidine. These medications, often prescribed off-label, have shown effectiveness in reducing hot flashes and night sweats. More recently, advancements in drug development have introduced targeted non-hormonal therapies such as neurokinin-3 (NK3) receptor antagonists, which directly act on brain pathways that regulate temperature, offering a novel mechanism of action for symptom relief. In addition to pharmaceuticals, there is increasing consumer interest in herbal supplements and plant-based remedies, such as black cohosh, soy isoflavones, and red clover.

These options appeal to women looking for natural or integrative approaches, further broadening the spectrum of non-hormonal interventions. This trend is particularly important for women who are not eligible for HRT due to medical contraindications or personal choice. As healthcare providers become more aware of and confident in these alternatives, and as patients demand safer and more personalized options, the market for non-hormonal therapies is expected to expand significantly. The growing preference for such treatments underscores a broader movement toward risk-averse, patient-centric care and is reshaping the direction of innovation in the menopausal hot flashes treatment landscape.

Key Market Players

  • Abbvie, Inc.
  • Allergan PLC.
  • Bayer Ag.
  • Cipla, Inc.
  • Eli Lilly and Company.
  • Emcure Pharmaceuticals Ltd.
  • GSK PLC.
  • Glenmark Pharmaceuticals Ltd.
  • Hisamitsu Pharmaceutical Co. Inc.
  • Merck & Co. Inc.

Report Scope:

In this report, the Global Menopausal Hot Flashes Treatment Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Menopausal Hot Flashes Treatment Market, By Type:

  • Oral
  • Liquid
  • Pill

Menopausal Hot Flashes Treatment Market, By Treatment Type:

  • Hormonal Treatment
  • Non-Hormonal Treatment
  • Alternative Treatment

Menopausal Hot Flashes Treatment Market, By Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Menopausal Hot Flashes Treatment Market, By Region:

  • North America
  • United States
  • Canada
  • Mexico
  • Europe
  • France
  • United Kingdom
  • Italy
  • Germany
  • Spain
  • Asia-Pacific
  • China
  • India
  • Japan
  • Australia
  • South Korea
  • South America
  • Brazil
  • Argentina
  • Colombia
  • Middle East & Africa
  • South Africa
  • Saudi Arabia
  • UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Menopausal Hot Flashes Treatment Market.

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Global Menopausal Hot Flashes Treatment Market report with the given market data, TechSci Research, offers customizations according to a company's specific needs. The following customization options are available for the report.

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Table of Contents

1. Product Overview
1.1. Market Definition
1.2. Scope of the Market
1.2.1. Markets Covered
1.2.2. Years Considered for Study
1.2.3. Key Market Segmentations
2. Research Methodology
2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations
3. Executive Summary
3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends
4. Voice of Customer
5. Global Menopausal Hot Flashes Treatment Market Outlook
5.1. Market Size & Forecast
5.1.1. By Value
5.2. Market Share & Forecast
5.2.1. By Type (Oral Liquid v/s Pill)
5.2.2. By Treatment Type (Hormonal Treatment, Non-Hormonal Treatment, Alternative Treatment)
5.2.2.1 Hormonal Treatment (Oestrogen, Oestrogen-Progesterone Combination, Progesterone)
5.2.2.2 Non-Hormonal Treatment (Clonidine, Gabapentin, Pregabalin, Brisdelle, Antidepressants)
5.2.2.3 Alternative Treatment (Vitamin E, Herbal Medicines, Black Cohosh)
5.2.3. By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies)
5.2.4. By Region
5.2.5. By CompaBy (2024)
5.3. Product Map
6. North America Menopausal Hot Flashes Treatment Market Outlook
6.1. Market Size & Forecast
6.1.1. By Value
6.2. Market Share & Forecast
6.2.1. By Type (Oral Liquid v/s Pill)
6.2.2. By Treatment Type (Hormonal Treatment, Non-Hormonal Treatment, Alternative Treatment)
6.2.2.1 Hormonal Treatment (Oestrogen, Oestrogen-Progesterone Combination, Progesterone)
6.2.2.2 Non-Hormonal Treatment (Clonidine, Gabapentin, Pregabalin, Brisdelle, Antidepressants)
6.2.2.3 Alternative Treatment (Vitamin E, Herbal Medicines, Black Cohosh)
6.2.3. By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies)
6.2.4. By Country
6.3. North America: Country Analysis
6.3.1. United States Menopausal Hot Flashes Treatment Market Outlook
6.3.1.1. Market Size & Forecast
6.3.1.1.1. By Value
6.3.1.2. Market Share & Forecast
6.3.1.2.1. By Type
6.3.1.2.2. By Treatment Type
6.3.1.2.3. By Distribution Channel
6.3.2. Canada Menopausal Hot Flashes Treatment Market Outlook
6.3.2.1. Market Size & Forecast
6.3.2.1.1. By Value
6.3.2.2. Market Share & Forecast
6.3.2.2.1. By Type
6.3.2.2.2. By Treatment Type
6.3.2.2.3. By Distribution Channel
6.3.3. Mexico Menopausal Hot Flashes Treatment Market Outlook
6.3.3.1. Market Size & Forecast
6.3.3.1.1. By Value
6.3.3.2. Market Share & Forecast
6.3.3.2.1. By Type
6.3.3.2.2. By Treatment Type
6.3.3.2.3. By Distribution Channel
7. Europe Menopausal Hot Flashes Treatment Market Outlook
7.1. Market Size & Forecast
7.1.1. By Value
7.2. Market Share & Forecast
7.2.1. By Type (Oral Liquid v/s Pill)
7.2.2. By Treatment Type (Hormonal Treatment, Non-Hormonal Treatment, Alternative Treatment)
7.2.2.1 Hormonal Treatment (Oestrogen, Oestrogen-Progesterone Combination, Progesterone)
7.2.2.2 Non-Hormonal Treatment (Clonidine, Gabapentin, Pregabalin, Brisdelle, Antidepressants)
7.2.2.3 Alternative Treatment (Vitamin E, Herbal Medicines, Black Cohosh)
7.2.3. By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies)
7.2.4. By Country
7.3. Europe: Country Analysis
7.3.1. France Menopausal Hot Flashes Treatment Market Outlook
7.3.1.1. Market Size & Forecast
7.3.1.1.1. By Value
7.3.1.2. Market Share & Forecast
7.3.1.2.1. By Type
7.3.1.2.2. By Treatment Type
7.3.1.2.3. By Distribution Channel
7.3.2. GermaBy Menopausal Hot Flashes Treatment Market Outlook
7.3.2.1. Market Size & Forecast
7.3.2.1.1. By Value
7.3.2.2. Market Share & Forecast
7.3.2.2.1. By Type
7.3.2.2.2. By Treatment Type
7.3.2.2.3. By Distribution Channel
7.3.3. United Kingdom Menopausal Hot Flashes Treatment Market Outlook
7.3.3.1. Market Size & Forecast
7.3.3.1.1. By Value
7.3.3.2. Market Share & Forecast
7.3.3.2.1. By Type
7.3.3.2.2. By Treatment Type
7.3.3.2.3. By Distribution Channel
7.3.4. Italy Menopausal Hot Flashes Treatment Market Outlook
7.3.4.1. Market Size & Forecast
7.3.4.1.1. By Value
7.3.4.2. Market Share & Forecast
7.3.4.2.1. By Type
7.3.4.2.2. By Treatment Type
7.3.4.2.3. By Distribution Channel
7.3.5. Spain Menopausal Hot Flashes Treatment Market Outlook
7.3.5.1. Market Size & Forecast
7.3.5.1.1. By Value
7.3.5.2. Market Share & Forecast
7.3.5.2.1. By Type
7.3.5.2.2. By Treatment Type
7.3.5.2.3. By Distribution Channel
8. Asia-Pacific Menopausal Hot Flashes Treatment Market Outlook
8.1. Market Size & Forecast
8.1.1. By Value
8.2. Market Share & Forecast
8.2.1. By Type (Oral Liquid v/s Pill)
8.2.2. By Treatment Type (Hormonal Treatment, Non-Hormonal Treatment, Alternative Treatment)
8.2.2.1 Hormonal Treatment (Oestrogen, Oestrogen-Progesterone Combination, Progesterone)
8.2.2.2 Non-Hormonal Treatment (Clonidine, Gabapentin, Pregabalin, Brisdelle, Antidepressants)
8.2.2.3 Alternative Treatment (Vitamin E, Herbal Medicines, Black Cohosh)
8.2.3. By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies)
8.2.4. By Country
8.3. Asia-Pacific: Country Analysis
8.3.1. China Menopausal Hot Flashes Treatment Market Outlook
8.3.1.1. Market Size & Forecast
8.3.1.1.1. By Value
8.3.1.2. Market Share & Forecast
8.3.1.2.1. By Type
8.3.1.2.2. By Treatment Type
8.3.1.2.3. By Distribution Channel
8.3.2. India Menopausal Hot Flashes Treatment Market Outlook
8.3.2.1. Market Size & Forecast
8.3.2.1.1. By Value
8.3.2.2. Market Share & Forecast
8.3.2.2.1. By Type
8.3.2.2.2. By Treatment Type
8.3.2.2.3. By Distribution Channel
8.3.3. Japan Menopausal Hot Flashes Treatment Market Outlook
8.3.3.1. Market Size & Forecast
8.3.3.1.1. By Value
8.3.3.2. Market Share & Forecast
8.3.3.2.1. By Type
8.3.3.2.2. By Treatment Type
8.3.3.2.3. By Distribution Channel
8.3.4. South Korea Menopausal Hot Flashes Treatment Market Outlook
8.3.4.1. Market Size & Forecast
8.3.4.1.1. By Value
8.3.4.2. Market Share & Forecast
8.3.4.2.1. By Type
8.3.4.2.2. By Treatment Type
8.3.4.2.3. By Distribution Channel
8.3.5. Australia Menopausal Hot Flashes Treatment Market Outlook
8.3.5.1. Market Size & Forecast
8.3.5.1.1. By Value
8.3.5.2. Market Share & Forecast
8.3.5.2.1. By Type
8.3.5.2.2. By Treatment Type
8.3.5.2.3. By Distribution Channel
9. South America Menopausal Hot Flashes Treatment Market Outlook
9.1. Market Size & Forecast
9.1.1. By Value
9.2. Market Share & Forecast
9.2.1. By Type (Oral Liquid v/s Pill)
9.2.2. By Treatment Type (Hormonal Treatment, Non-Hormonal Treatment, Alternative Treatment)
9.2.2.1 Hormonal Treatment (Oestrogen, Oestrogen-Progesterone Combination, Progesterone)
9.2.2.2 Non-Hormonal Treatment (Clonidine, Gabapentin, Pregabalin, Brisdelle, Antidepressants)
9.2.2.3 Alternative Treatment (Vitamin E, Herbal Medicines, Black Cohosh)
9.2.3. By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies)
9.2.4. By Country
9.3. South America: Country Analysis
9.3.1. Brazil Menopausal Hot Flashes Treatment Market Outlook
9.3.1.1. Market Size & Forecast
9.3.1.1.1. By Value
9.3.1.2. Market Share & Forecast
9.3.1.2.1. By Type
9.3.1.2.2. By Treatment Type
9.3.1.2.3. By Distribution Channel
9.3.2. Argentina Menopausal Hot Flashes Treatment Market Outlook
9.3.2.1. Market Size & Forecast
9.3.2.1.1. By Value
9.3.2.2. Market Share & Forecast
9.3.2.2.1. By Type
9.3.2.2.2. By Treatment Type
9.3.2.2.3. By Distribution Channel
9.3.3. Colombia Menopausal Hot Flashes Treatment Market Outlook
9.3.3.1. Market Size & Forecast
9.3.3.1.1. By Value
9.3.3.2. Market Share & Forecast
9.3.3.2.1. By Type
9.3.3.2.2. By Treatment Type
9.3.3.2.3. By Distribution Channel
10. Middle East and Africa Menopausal Hot Flashes Treatment Market Outlook
10.1. Market Size & Forecast
10.1.1. By Value
10.2. Market Share & Forecast
10.2.1. By Type (Oral Liquid v/s Pill)
10.2.2. By Treatment Type (Hormonal Treatment, Non-Hormonal Treatment, Alternative Treatment)
10.2.2.1 Hormonal Treatment (Oestrogen, Oestrogen-Progesterone Combination, Progesterone)
10.2.2.2 Non-Hormonal Treatment (Clonidine, Gabapentin, Pregabalin, Brisdelle, Antidepressants)
10.2.2.3 Alternative Treatment (Vitamin E, Herbal Medicines, Black Cohosh)
10.2.3. By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies)
10.2.4. By Country
10.3. MEA: Country Analysis
10.3.1. South Africa Menopausal Hot Flashes Treatment Market Outlook
10.3.1.1. Market Size & Forecast
10.3.1.1.1. By Value
10.3.1.2. Market Share & Forecast
10.3.1.2.1. By Type
10.3.1.2.2. By Treatment Type
10.3.1.2.3. By Distribution Channel
10.3.2. Saudi Arabia Menopausal Hot Flashes Treatment Market Outlook
10.3.2.1. Market Size & Forecast
10.3.2.1.1. By Value
10.3.2.2. Market Share & Forecast
10.3.2.2.1. By Type
10.3.2.2.2. By Treatment Type
10.3.2.2.3. By Distribution Channel
10.3.3. UAE Menopausal Hot Flashes Treatment Market Outlook
10.3.3.1. Market Size & Forecast
10.3.3.1.1. By Value
10.3.3.2. Market Share & Forecast
10.3.3.2.1. By Type
10.3.3.2.2. By Treatment Type
10.3.3.2.3. By Distribution Channel
11. Market Dynamics
11.1. Drivers
11.2. Challenges
12. Market Trends & Developments
12.1. Recent Development
12.2. Mergers & Acquisitions
12.3. Product Launches
13. Global Menopausal Hot Flashes Treatment Market: SWOT Analysis
14. Porter’s Five Forces Analysis
14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products
15. Competitive Landscape
15.1 Abbvie, Inc.
15.2 Allergan PLC.
15.3 Bayer Ag.
15.4 Cipla, Inc.
15.5 Eli Lilly and CompaBy.
15.6 Emcure Pharmaceuticals Ltd.
15.7 GSK PLC.
15.8 Glenmark Pharmaceuticals Ltd.
15.9 Hisamitsu Pharmaceutical Co. Inc.
15.10 Merck & Co. Inc.
16. Strategic Recommendations17. About the Publisher & Disclaimer

Companies Mentioned

  • Abbvie, Inc.
  • Allergan PLC.
  • Bayer Ag.
  • Cipla, Inc.
  • Eli Lilly and Company.
  • Emcure Pharmaceuticals Ltd.
  • GSK PLC.
  • Glenmark Pharmaceuticals Ltd.
  • Hisamitsu Pharmaceutical Co. Inc.
  • Merck & Co. Inc.

Table Information