Rheumatoid Arthritis Therapeutics Market Report and Forecast 2025-2034

The rheumatoid arthritis therapeutics market was valued at USD 29.50 billion in 2024, driven by the increasing prevalence of rheumatoid arthritis across the globe. The market is expected to grow at a CAGR of 4.60% during the forecast period of 2025-2034, reaching a value of USD 46.26 billion by 2034.

Rheumatoid Arthritis Therapeutics Market Overview

Rheumatoid arthritis (RA) is an auto-immune disorder, a condition in which a person's immune system identifies one's cellular and organ makeup as antigenic entities, resulting in the synthesis of antibodies against one's own body. The disease tends to attack the linings of the joints leading to bone abrasion, joint inflammation, and severe pain. If left untreated, the disease could spread across various organs, which initially affect the joints of fingers and toes. A surge in obesity rates, increasing awareness concerning rheumatic disorders, and the rising geriatric population have significantly contributed to the market growth. Additionally, the rise in generic drug approvals and growth in clinical trials reflects the ongoing expansion of the market.

Rheumatoid Arthritis Therapeutics Market Growth Drivers

Growing Prevalence of Rheumatoid Arthritis Drives the Market Demand

A significant driver in the market includes the growing prevalence of the disease. Recent data reveals that around 1.5 million people in the United States are affected by rheumatoid arthritis. Moreover, females are reported to be nearly three times more likely to develop the autoimmune condition as compared to males. Research has shown that early treatment can put the disease into remission, reflecting the importance of effective therapeutics to manage the condition. Thus, with the rising cases of the disease, the market demand for these drugs is expected to witness a rise. Further, the increasing aging population which is at a higher risk of developing the disorder is poised to influence the market landscape.

Rheumatoid Arthritis Therapeutics Market Trends

Several trends and developments are being observed in the market to enhance the current situation. Some of the noteworthy trends are as follows:

Rising Entry of Generic Drugs Supports the Market Expansion

In August 2023, an Indian multinational pharmaceutical company Zydus Lifesciences Limited received the United States US Food and Drug Administration's (FDA) approval to manufacture and market its generic Indomethacin suppositories (50 mg strength), a non-steroidal and anti-inflammatory drug used for the treatment of moderate to severe rheumatoid arthritis. The FDA also granted a 180-day competitive generic therapy (CGT) exclusivity to market the generic treatment drug as it deemed there is inadequate generic competition for the drug in the United States market. The rise in the approval of generic therapeutics indicated for rheumatoid arthritis is likely to improve the accessibility of treatment alternatives to the growing patient pool, which is projected to bolster the market growth in the forecast period.

Surge in Clinical Trials of Novel Therapies to Meet the Rising Rheumatoid Arthritis Therapeutics Market Demand

One of the major market trends is the growth in clinical trials of new and advanced rheumatoid arthritis medications which are anticipated to enhance patient outcomes and stimulate market expansion. In October 2023, a United States-based biotechnology company Rise Therapeutics revealed that the regulatory agency FDA has accepted its investigational new drug (IND) application that will allow initiation of the Phase I clinical trial of R-2487 intended for the treatment of rheumatoid arthritis. In the single and repeat-dose clinical study enrolling 36 subjects, the cellular immunotherapy R-2487 will be assessed for tolerability, drug exposure, safety, and clinical activity. It is reported that the clinical activity of R-2487 will be evaluated by measuring improvement in rheumatoid arthritis disease severity and other biomarkers. The development of such oral immunotherapy treatments that can facilitate ease of delivery of protein-based biologics therapy and are available at reduced costs are projected to positively impact the market dynamics.

Rising Preference for Combination Therapies is Projected to Boost Rheumatoid Arthritis Therapeutics Market Size

Treatments for rheumatoid arthritis manage inflammation in the affected patients and can ease associated symptoms like pain and stiffness. However, sometimes a single drug is not sufficient to treat this autoimmune disease. In such cases, patients are prescribed with more than one drug to effectively control the symptoms. For example, a treatment that combines ethotrexate with leflunomide or methotrexate with sulfasalazine is reported to be the most effective two-drug combinations of conventional disease-modifying antirheumatic drugs (DMARDs) . The rising demand for combination therapies due to their ability to provide better clinical benefits is anticipated to fuel the market size.

Advances in Personalized Medicine is Likely to Elevate Rheumatoid Arthritis Therapeutics Market Value

The rising advancements in personalized treatment approaches supported by robust research initiatives is resulting in tailored therapies that can improve patient outcomes. Biomarkers are increasingly employed as key tools in the development of personalized medicine towards rheumatoid arthritis to accurately predict the patient’s disease phenotype and response to treatment. Further, the growing innovation in omic technologies and clinical study design is expected to accelerate rheumatoid biomarker discovery, which is likely to amplify the demand for precision medicine, thereby stimulating market growth.

Rheumatoid Arthritis Therapeutics Market Segmentation

“Rheumatoid Arthritis Therapeutics Market Report and Forecast 2025-2034” offers a detailed analysis of the market based on the following segments:

Market Breakup by Product Type

• Biologics
• Non-Biologics
• Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
• Synthetic Disease-Modifying Antirheumatic Drugs (SDMARDs)
• Others

Market Breakup by Sales Type

• Prescription
• Over The Counter (OTC)
• Others

Market Breakup by Route of Administration

• Oral
• Parenteral

Market Breakup by Distribution Channel

• Hospital Pharmacy
• Retail Pharmacy
• Online

Market Breakup by End User

• Hospitals & Clinics
• Research and Academic Laboratories
• Others

Market Breakup by Region

• United States
• EU-4 and United Kingdom
• Germany
• France
• Italy
• Spain
• United Kingdom
• Japan
• India

Rheumatoid Arthritis Therapeutics Market Share

Market Segmentation Based on Product Type is Poised to Propel Market Growth

The market segmentation by product type includes biologics and non-biologics. Biologics include advanced drugs such as tumor necrosis factor (TNF) inhibitors and interleukin inhibitors. These medications target specific parts of the immune system responsible for inflammation in rheumatoid arthritis. Non-biologics are further subdivided into non-steroidal anti-inflammatory drugs (NSAIDs), synthetic disease-modifying antirheumatic drugs (SDMARDs) like methotrexate, and other medications including corticosteroids that help manage symptoms or certain complications. There is a growing demand for biologics due to their ability to prevent long-term disability associated with the disease is likely to augment the rheumatoid arthritis therapeutics market demand.

Prescription and Over-the-Counter Rheumatoid Arthritis Therapeutics are Witnessing Market Demand

Based on the sales type, the market comprises prescription, and over-the-counter rheumatoid arthritis therapeutics, among others. Prescription drugs hold a significant share, including majority of rheumatoid arthritis therapies that require medical oversight due to their potential side effects. Over-the-counter (OTC) drugs, mainly some non-steroidal anti-inflammatory (NSAIDs), are available without a prescription to manage pain and inflammation. Advil and Aleve are some examples of widely used rheumatoid arthritis drugs that are sold over-the-counter.

Rheumatoid Arthritis Therapeutics Market Analysis by Region

The market is witnessing colossal growth in United States due to the highest reported disease cases. Moreover, the increasing awareness and health consciousness among people have significantly contributed to the dominant share of the regional market. Also, the increasing budget allocation in the arena of rheumatoid arthritis therapeutics equally raises its market value.

EU-4 and the United Kingdom has seen significant propellants in the form of innovative drugs, advanced healthcare alternatives to grapple with the disease, and an increment in cases. In the Asia Pacific region, Japan, and India’s market growth is catalyzed by the improvement in healthcare infrastructure, increasing awareness, and growing adoption of biologics.

Leading Players in the Rheumatoid Arthritis Therapeutics Market

The key features of the market report include patent analysis, grants analysis, clinical trials analysis, funding and investment analysis, partnerships, and collaborations analysis by the leading key players. The major companies in the market are as follows:

• Pfizer Inc
• Amgen Inc
• Bristol-Myers Squibb Company
• F. Hoffmann-La Roche Ltd
• UCB S.A.
• Gilead Sciences, Inc
• Boehringer Ingelheim GmbH
• Novartis International AG
• Regeneron Pharmaceuticals, Inc
• AbbVie
• Eli Lilly and Company
• Celgene Corporation

Kindly note that this only represents a partial list of companies, and the complete list has been provided in the report.

Key Questions Answered in the Rheumatoid Arthritis Therapeutics Market Report

• What was the rheumatoid arthritis therapeutics market value in 2023?
• What is the rheumatoid arthritis therapeutics market forecast outlook for 2025-2034?
• What are the regional markets covered in the report?
• What is market segmentation based on product type?
• What is the market breakup based on sales type?
• What is the market breakup by route of administration?
• What are the various distribution channels present in the market?
• What are the major end users in the market?
• What are the major factors aiding the rheumatoid arthritis therapeutics market demand?
• How has the market performed so far and how is it anticipated to perform in the coming years?
• What are the market's major drivers, opportunities, and restraints?
• Which regional market is expected to lead the market share in the forecast period?
• Which country is expected to experience expedited growth during the forecast period?
• How does the prevalence and incidence of rheumatoid arthritis affect the market landscape?
• What are the major rheumatoid arthritis therapeutics market trends?
• How does the rise in the geriatric population impact the market size?
• Which product type will dominate the market share?
• Which sales type is expected to have a high market value in the coming years?
• Which route of administration will experience the highest demand in the market segment?
• Which distribution channel is poised to cover a major market share?
• Which end user is anticipated to drive market growth?
• Who are the key players involved in the rheumatoid arthritis therapeutics market?
• What clinical trials are undergoing in the market?
• What is the patent landscape of the market?
• What are the current unmet needs and challenges in the market?
• How are partnerships, collaborations, mergers and acquisitions among the key market players shaping the market dynamics?

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