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A Researcher's Guide to Rodent Behavior. Experimental Designs, Methods and Protocols. Handbook of Behavioral Neuroscience Volume 32

  • Book

  • March 2024
  • Elsevier Science and Technology
  • ID: 5789636

A Researcher's Guide to Rodent Behavior: Experimental Designs, Methods and Protocols, Volume 32 provides a comprehensive guide to all forms of behavioral processes found in mice, rats and other rodents used in behavioral and cognitive research. Sections discuss basic skills necessary for successful rodent behavior research, including experimental design, animal selection, building any necessary apparatus, ethical considerations and interpretation of results. The book provides useful guidance for researchers at all stages of their careers, including a detailed description of how to perform stereotaxic surgery on the rat or mouse brain, advice on how to non-appetitively motivate rodents, and more.

Most significantly, the book contains 35 proven, clearly defined protocols to aid readers in their research, making it one of the few books available that provides a collection of such protocols in a single publication. The cognitive, motor, sensory, affective, and species-typical protocols are profusely illustrated with full-color photographs from the author's own research, to help readers more fully understand the studies and methods discussed in the text and provide further instruction on the ideal ways to re-create research projects themselves.

Table of Contents

1. Why Use Animals?
2. Laboratory Animals: Brief History, Choosing the Best Animal for the Job
3. Making Apparatus
4. Dementia and Other Illnesses
5. The Hippocampus in Man and Animals
6. Planning
7. Statistical Analysis
8. Motor Protocols
9. Sensory Protocols
10. Species-Typical Protocols
11. Cognitive Protocols
12. Affective Protocols
13. Stereotaxic Techniques

Authors

Robert M.J. Deacon research lecturer, Department of Experimental Psychology, South Parks Road, University of Oxford, Oxford, UK. Dr. Deacon is a research lecturer in the Department of Experimental Psychology, University of Oxford, who specializes in animal models of neurodegenerative diseases, particularly in the role of the hippocampus and associated cortex in Alzheimer's disease. He has more than forty years of experience "at the bench� performing behavioral testing on manifold rodent species, and has published more than 100 research articles and methods papers on rodent behavior investigations. Daniela Schulz Associate Professor, Bogazi�i University, Institute of Biomedical Engineering, Center for Life Sciences and Technologies, Kandilli Campus, Istanbul, T�rkiye. Dr. Schulz is faculty at Bogazi�i University, Institute of Biomedical Engineering and Center for Life Sciences and Technologies, in Istanbul, T�rkiye. Trained in psychology, behavioral neuroscience, and behavioral neuroimaging, the behavioral sciences are key to all of her projects. Her research typically focuses on methods development, including animal models of psychiatric and neurological disease, preclinical neuroimaging, experience-dependent deep brain stimulation, and more. While her work is inter-disciplinary and inter-sectoral, behavior remains the gateway to studying the brain systemically, dynamically, and in all its complexity.