Bioresorbable Polymers and their Composites: Characterization and Fundamental Processing for Pharmaceutical and Medical Device Development provides a holistic view of these unique materials and their usage in a range of biomedical applications. The book is evenly divided between fundamentals, processing methods and modeling approaches, and includes detailed coverage of a variety of applications, such as drug delivery, medical devices and wound healing. Key aspects including biocompatibility, biodegradability and toxicology are also thoroughly covered, enabling the reader to be fully informed when fabricating and utilizing their selected bioresorbable polymer.
This book is an interdisciplinary and important reference for researchers in the fields of materials science, biomedical engineering, pharmaceutical science and regenerative medicine, as well as R&D groups in the development of medical devices.
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Table of Contents
SECTION 1 Fundamentals, processing, and modelling 1. Introduction to bioresorbable polymers: Types and biomedical applications 2. Bioresorbable polymers and their composites for biomedical applications 3. Processing techniques for bioresorbable-based composites for medical device applications 4. PCL-based composites and their utilizations in the medical sector 5. Processing of PLA/PLLA-based composites for medical device applications 6. PHA/PHB/PHBV-based composites: development and biomedical applications 7. Synthesis and applications of bioresorbable polymers for tissue engineering scaffolds 8. Gelation and fabrication of bioresorbable-based hydrogels for drug-release applications 9. Molecular modeling of polymers for efficient drug-carrier applications 10. Electrospinning technique: A potential method to develop bioresorbable-based medical devices 11. Modeling of drug release from a bioresorbable polymer matrix system SECTION 2 Biomedical applications 12. Bioresorbable polymers: A prospective utilization as an implant 13. Polymeric (PLGA-based) nanocomposites for application in drug delivery: Current state of the art and forthcoming perspectives 14. Bioresorbable polymers: Challenges and opportunities for development and applications of medical devices 15. Bioresorbable polymers for wound healing 16. Bioresorbable polymers/HNT blend composite wound dressings 17. Biobehavioral structure, elastic, optical, and thermoluminescence properties of AlxCay-xNd01P70 bioglasses 18. A prospective utilization of biodegradable polymers for controlled drug-delivery applications 19. Bioresorbable polymer-based sensors for medical applications
Authors
Deepak Verma Assistant Professor, Department of Mechanical Engineering, Graphic Era Hill University, Dehradun, India. Deepak Verma is currently working as an Assistant Professor, in the Department of Mechanical Engineering, at Graphic Era Hill University, Dehradun, India. He received his M.Tech from the College of Technology, GBPUA&T Pantnagar, India. He has more than 7 years of experience in teaching, research, and working within industry. His research interests include: Hybrid Reinforced/Filled Polymer Composites, Advance Materials: Graphene and Nanoclay, Wood fiber Reinforced/Filled Polymer Composites, Modification and Treatment of Natural Fibres and Solid Wood Composites, and Polymer blends. He has published 2 books, 16 book chapters, and more than 10 International journal papers in reputed journals. Manunya Okhawilai Researcher, Metallurgy and Materials Science Research Institute, Chulalongkorn University, Bangkok, Thailand. Dr. Manunya Okhawilai is a researcher at Metallurgy and Materials Science Research Institute, Chulalongkorn University. Her interest lies in polymer blends and polymer composite. Her main research areas are ballistic armour made from pure polymer composite, bipolar plate for polymer electrolyte membrane fuel cell and solid-state polymer electrolyte for energy storage.She has published over 20 publications including conference papers. Moreover, she has published book chapters in "Advanced and Emerging Polybenzoxazine Science and Technology� published by Elsevier. Kheng-Lim Goh Director of Research and Associate Professor in Mechanics of Materials, Newcastle University of Singapore, Singapore. Prof Kheng-Lim Goh is the director of research at the Newcastle University of Singapore, and associate professor in mechanics of materials. He leads the Advanced Composite Research Group where the research is focused on the mechanics of composite materials, covering development (lightweight composite materials), damage studies and repair, sustainability (UN SDG, Net Zero), mechanical systems and structures underpinning composite materials, with applications from aerospace, to automotive, construction and biomedical industry. He has published 100+ research articles in several international journals, conference proceedings and book chapters. As a Global Engagement Fellow presently he is working with his colleagues at University of Pittsburg, USA, on materials and sustainability. Seeram Ramakrishna Professor, Department of Mechanical Engineering, National University of Singapore, Singapore. Seeram Ramakrishna is the Director of the Center for Nanofibres and Nanotechnology at the National University of Singapore (NUS), which is ranked among the top 20 universities in the world. He is regarded as the modern father of electrospinning. He is an elected Fellow of UK Royal Academy of Engineering (FREng); Singapore Academy of Engineering; Indian National Academy of Engineering; and ASEAN Academy of Engineering & Technology. He is an elected Fellow of the International Union of Societies of Biomaterials Science and Engineering (FBSE); Institution of Engineers Singapore; ISTE, India; Institution of Mechanical Engineers and Institute of Materials, Minerals & Mining, UK; and American Association of the Advancement of Science; ASM International; American Society for Mechanical Engineers; American Institute for Medical & Biological Engineering, USA. He is an editor of Elsevier journal Current Opinion in Biomedical Engineering. Pooria Pasbakhsh Associate Professor, Department of Mechanical Engineering, School of Engineering, Monash University Malaysia, Selangor Darul Ehsan, Malaysia. Dr. Pooria Pasbakhsh has been an Associate Professor in the School of Engineering at Monash University Malaysia since 2010. His research interests include clay nanoparticles, self-healing materials, rubber nanocomposites, and industrial applications of polymer composites. Dr. Pasbakhsh has published over 100 journal or conference papers, co-edited 3 books, and participated as an invited speaker or chair at several conferences. He has also participated in numerous collaborations aiming to integrate industry needs into academic research, and to support composite industry applications. Mohit Sharma A*STAR (Agency for Science, Technology and Research), Singapore. Dr Sharma's current assignments are focused on lead technology acquisition for advanced materials innovative. He has lead major research projects in liaison with key industries and high value ventures, which aims to create social impact and value capture. He is proficiently contributing to filing patents (US, Singapore), industrial know-hows, technology showcases and publishing peer reviewed research papers in the area of advanced composites materials, energy saving/heat regulating coatings and tribological materials. His current research interests are composites materials processing & analyses, Nano-structured fiber-polymer interphases, Carbon/glass/polymer/natural fibers reinforced nano-composites, Nano-ceramics/metal oxide based coatings for energy saving and UV shielding applications, Industrial coatings and paint additives, Aviation grease degradation and RUL, Solid lubricants, Tribological analysis of materials in harsh environments, advanced structural materials development for aerospace, marine offshore and biomedical arenas. Before joining A*STAR in 2013, Dr Sharma worked as a Guest Scientist at Leibniz Institute of Polymer Research (IPF) Dresden, Germany and Institute of Lightweight Structures and Polymer Technology (ILK) Technical University (TU) Dresden, Germany.
