Haleon, formed in 2022 from GSK’s consumer health unit, focuses on over-the-counter solutions. The industry is moderately concentrated, with Takeda and AstraZeneca leading prescription drugs. Innovations target long-acting PPIs and non-drug therapies. Challenges include generic competition, side effect concerns, and regulatory scrutiny, yet rising GERD prevalence drives growth.
Market Size and Growth Forecast
The global GERD & NERD Treatment market is projected to reach USD 7.5-8.5 billion by 2025, with an estimated compound annual growth rate (CAGR) of 2% to 3% through 2030. Growth is driven by aging populations and lifestyle-related GERD cases.Regional Analysis
- North America holds 35-40%, with a growth rate of 2%-3%. The U.S. leads in hospital treatments, with Canada focusing on drugstores. Trends include OTC adoption.
 - Asia Pacific accounts for 25-30%, with a growth rate of 3%-4%. Japan’s Eisai and India’s Dr. Reddy’s drive drugstore sales. Trends focus on generics.
 - Europe holds 30-35%, with a growth rate of 2%-3%. Germany’s STADA focuses on PPIs. Trends include non-drug therapies.
 - Middle East and Africa hold 2-3%, with a growth rate of 1%-2%. The UAE’s hospitals grow, but access lags. Trends include affordability.
 - South America accounts for 1-2%, with a growth rate of 1%-2%. Brazil’s drugstores support demand. Trends focus on generics.
 
Application Analysis
- Hospitals & Clinics: Holds 50-60%, with a growth rate of 2%-3%. Takeda’s PPIs dominate hospital prescriptions. Trends include combination therapies.
 - Drugstore: Accounts for 40-45%, with a growth rate of 2.5%-3.5%. Haleon’s OTC solutions lead. Trends focus on self-medication.
 - Research Centers: Holds 0-1%, with a growth rate of 1%-2%. AbbVie’s trials grow. Trends include novel drugs.
 - Others: Accounts for 0-1%, with a growth rate of 1%-2%. Niche therapies grow with Sandoz’s offerings.
 
Type Analysis
- Proton Pump Inhibitors: Holds 75-80%, with a growth rate of 2%-3%. AstraZeneca’s PPIs lead. Trends include long-acting formulations.
 - H2 Receptor Blocker: Accounts for 5-10%, with a growth rate of 1%-2%. Teva’s blockers grow. Trends focus on affordability.
 - Petroleum Cracking Method (Antacids): Holds 10-15%, with a growth rate of 1.5%-2.5%. Haleon’s antacids lead. Trends include fast-acting solutions.
 - Others: Accounts for 1-3%, with a growth rate of 1%-2%. Novel therapies grow with Eisai’s offerings.
 
Key Market Players
- Takeda Pharmaceutical: A Japanese firm, Takeda develops PPIs for hospitals.
 - AstraZeneca: A UK company, AstraZeneca focuses on PPIs for clinics.
 - Haleon: A UK firm, Haleon supplies OTC antacids.
 - Teva Pharmaceutical: An Israeli company, Teva develops H2 blockers.
 - Eisai: A Japanese firm, Eisai focuses on novel therapies.
 - Aurobindo Pharma: An Indian company, Aurobindo supplies generics.
 - Dr. Reddy’s Laboratories: An Indian firm, Dr. Reddy’s develops PPIs.
 - STADA: A German company, STADA focuses on OTC PPIs.
 - AbbVie: A U.S. firm, AbbVie supplies hospital therapies.
 - Johnson & Johnson: A U.S. company, Johnson & Johnson develops antacids.
 - Sandoz: A Swiss firm, Sandoz focuses on generics.
 - Viatris: A U.S. company, Viatris supplies H2 blockers.
 
Porter’s Five Forces Analysis
- Threat of New Entrants: Low. Regulatory barriers deter entry, with AstraZeneca dominating.
 - Threat of Substitutes: Moderate. Non-drug therapies compete, but Takeda’s PPIs retain efficacy.
 - Bargaining Power of Buyers: High. Pharmacies switch suppliers, pressuring Haleon for pricing.
 - Bargaining Power of Suppliers: Low. API suppliers have limited influence, with Teva’s scale reducing dependency.
 - Competitive Rivalry: High. AstraZeneca and Takeda compete on efficacy and pricing.
 
Market Opportunities and Challenges
Opportunities
- Aging Population: GERD prevalence boosts Takeda’s sales.
 - OTC Growth: Self-medication drives Haleon’s expansion.
 - Generic Expansion: India’s demand favors Dr. Reddy’s growth.
 - Emerging Markets: Brazil’s drugstores support Aurobindo’s share.
 - Novel Therapies: Non-drug solutions boost Eisai’s adoption.
 - Hospital Demand: Combination therapies favor AbbVie’s growth.
 - Lifestyle Trends: Dietary habits enhance STADA’s revenue.
 
Challenges
- Generic Competition: Low-cost drugs pressure AstraZeneca’s margins.
 - Side Effect Concerns: PPI risks affect Takeda’s adoption.
 - Regulatory Scrutiny: Approvals slow Haleon’s innovation.
 - Market Saturation: Mature markets challenge Dr. Reddy’s expansion.
 - Supply Chain Issues: API delays disrupt Aurobindo’s delivery.
 - Non-Drug Therapies: Lifestyle changes threaten Eisai’s share.
 - Pricing Pressures: Reimbursement cuts affect STADA’s profitability.
 
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Table of Contents
Companies Mentioned
- Takeda Pharmaceutical
 - AstraZeneca
 - Haleon
 - Teva Pharmaceutical
 - Eisai
 - Aurobindo Pharma
 - Dr. Reddy's Laboratories
 - STADA
 - AbbVie
 - Johnson & Johnson
 - Sandoz
 - Viatris
 

